Allylation of bulky-substituted aromatic aldehydes with allyltrichlorosilanes were catalyzed by axial biscarboline N.N-dioxide esters with high enaiitioselectivities up to 92% e.e. for l-(4-chlorophenyl)-9-methyl-9Hpy...Allylation of bulky-substituted aromatic aldehydes with allyltrichlorosilanes were catalyzed by axial biscarboline N.N-dioxide esters with high enaiitioselectivities up to 92% e.e. for l-(4-chlorophenyl)-9-methyl-9Hpyrido[3,4-b]indole-3-carbaldehyde and 90% e.e.for 1-(3-methoxyphenyl)-9-methyl-9H-pyrido[3,4-b]indole-3-carbaldehyde, respectively.Total 22 aldehydes were tested with good yields and enantioselectivities.Catalyst 4f exhibited good catalytic enantioselectivity.展开更多
文摘Allylation of bulky-substituted aromatic aldehydes with allyltrichlorosilanes were catalyzed by axial biscarboline N.N-dioxide esters with high enaiitioselectivities up to 92% e.e. for l-(4-chlorophenyl)-9-methyl-9Hpyrido[3,4-b]indole-3-carbaldehyde and 90% e.e.for 1-(3-methoxyphenyl)-9-methyl-9H-pyrido[3,4-b]indole-3-carbaldehyde, respectively.Total 22 aldehydes were tested with good yields and enantioselectivities.Catalyst 4f exhibited good catalytic enantioselectivity.
