To the Editor:Tropomyosin receptor kinase A/B/C(TRKA/B/C)are encoded by neurotrophic tyrosine receptor kinase 1/2/3(NTRK1/2/3),respectively.NTRK gene fusions are the most common drivers of malignancies.Additionally,TR...To the Editor:Tropomyosin receptor kinase A/B/C(TRKA/B/C)are encoded by neurotrophic tyrosine receptor kinase 1/2/3(NTRK1/2/3),respectively.NTRK gene fusions are the most common drivers of malignancies.Additionally,TRKA is the most common oncogene in TRK family,which is detected in 7.4%of human tumors.展开更多
基金supported by the National Natural Science Foundation of China (Grants 81922064, 22177083, 82273770)Natural Science Foundation of Sichuan Province (Grant 2022NSFSC1290, China)the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences (Grant 2020-JKCS-014, China)
文摘To the Editor:Tropomyosin receptor kinase A/B/C(TRKA/B/C)are encoded by neurotrophic tyrosine receptor kinase 1/2/3(NTRK1/2/3),respectively.NTRK gene fusions are the most common drivers of malignancies.Additionally,TRKA is the most common oncogene in TRK family,which is detected in 7.4%of human tumors.