A novel thiazolothiazole-bridged imidazole derivative(1) was found to exhibit blue fluorescence in gaseous state or in methanol and yellow fluorescence in solid state. The N-alkylation of imidazole subunit(s) in 1 usi...A novel thiazolothiazole-bridged imidazole derivative(1) was found to exhibit blue fluorescence in gaseous state or in methanol and yellow fluorescence in solid state. The N-alkylation of imidazole subunit(s) in 1 using n-propyl iodide generated unsymmetrically or symmetrically alkylated thiazolothiazolebridged imidazolium salts with good water solubility and remarkably strong emission in solution. Furthermore, the replacement of iodide counter-anion by triflate or bis(trifluoromethane sulfonyl)imide achieved remarkably strong emission in solid state and in solution as well as good water solubility. The strong fluorescence of dicationic salts with triflate and NTf_(2)^(-)counter-anions in solid state can be ascribed to their twisted and rigid structures induced by interionic C-H···F hydrogen bonding.展开更多
To discover novel fluoro p hores of solution and solid dual-state emission(DSE) materials,unique V-shape furo[2,3-b]furans have been designed and synthesized by a one-pot method for the first time and their photolumin...To discover novel fluoro p hores of solution and solid dual-state emission(DSE) materials,unique V-shape furo[2,3-b]furans have been designed and synthesized by a one-pot method for the first time and their photoluminescent properties have been explored in benzene,THF,DMF and DMSO,as well as in the solid state.As the best example,2,5-bis(4-(9 H-carbazol-9-yl)phenyl)-6 a-amino-3 a,6 a-dihydrofuro[2,3-b]furan-3,3 a,4-trica rbonitrile(3 g) exhibited solution and solid DSE properties in THF,benzene,and in the solid state with quantum yields of 55%,92%,and 45%,respectively.展开更多
Developing dual-state luminophores(DSLs)with strong fluorescence in both the monomer and aggregate states is urgently needed but remains a huge challenge because most current luminophores are either aggregation-induce...Developing dual-state luminophores(DSLs)with strong fluorescence in both the monomer and aggregate states is urgently needed but remains a huge challenge because most current luminophores are either aggregation-induced emission or aggregation-caused quenching molecules.Moreover,limited by the structural conservation of the few existing DSLs,there are not enough response sites that can be used to customize various activatable fluorescent probes for specific molecular imaging.Herein,we engineered a general integration strategy for the fabrication of such DSLs with excellent photophysical properties.The DSLs,with their tunable spectra,a large Stokes shift(>170 nm),and achievable near-infrared(NIR)emission,show great potential for high-contrast imaging.Importantly,DSLs can be used as a universal platform for probe customization due to their activatable fluorescence through protection-deprotection of the phenolic hydroxyl group.Based on this,an NIR fluorescent probe DSL-Gal was developed for sensing of β-galactosidase in solutions,senescent cells,and liver metastases with high contrast,further confirming the superiority and universal feasibility of DSLs in probe design.The integration strategy may provide a novel approach for the generation of other DSLs and have great potential applications in bioimaging.展开更多
A new dual-state emission(DSE) dye comprised of tetraphenylethene(TPE), triphenylamine(TPA), and indoline groups has been synthesized, which showed efficient fluorescence in both solution and solid. The dye is compris...A new dual-state emission(DSE) dye comprised of tetraphenylethene(TPE), triphenylamine(TPA), and indoline groups has been synthesized, which showed efficient fluorescence in both solution and solid. The dye is comprised of three parts and these parts show different fluorescence properties which can be very useful in some applications since the dye can produce information-rich responses. For example, the dye is p H-sensitive in both solution and solid states, and it emits yellow fluorescence in normal p H and red/NIR fluorescence in acidic condition. Cytotoxicity of the dye is low at concentration of 3 μM which was confirmed by a methyl thiazolyl tetrazolium(MTT) experiment, and in vitro experiments revealed that the p H responsive performance can be used in bioimaging. It provides a novel p H-sensitive DSE dye ever reported, which has potential application in many fields.展开更多
In the multi-radar networking system,aiming at the problem of locating long-distance targets synergistically with difficulty and low accuracy,a dual-station joint positioning method based on the target measurement err...In the multi-radar networking system,aiming at the problem of locating long-distance targets synergistically with difficulty and low accuracy,a dual-station joint positioning method based on the target measurement error feature complementarity is proposed.For dual-station joint positioning,by constructing the target positioning error distribution model and using the complementarity of spatial measurement errors of the same long-distance target,the area with high probability of target existence can be obtained.Then,based on the target distance information,the midpoint of the intersection between the target positioning sphere and the positioning tangent plane can be solved to acquire the target's optimal positioning result.The simulation demonstrates that this method greatly improves the positioning accuracy of target in azimuth direction.Compared with the traditional the dynamic weighted fusion(DWF)algorithm and the filter-based dynamic weighted fusion(FBDWF)algorithm,it not only effectively eliminates the influence of systematic error in the azimuth direction,but also has low computational complexity.Furthermore,for the application scenarios of multi-radar collaborative positioning and multi-sensor data compression filtering in centralized information fusion,it is recommended that using radar with higher ranging accuracy and the lengths of baseline between radars are 20–100 km.展开更多
基金National Natural Science Foundation of China(Nos.U20041101,21772034,U1704251)the Top-notch Personnel Fund of Henan Agricultural University(No.30500418)for financial support。
文摘A novel thiazolothiazole-bridged imidazole derivative(1) was found to exhibit blue fluorescence in gaseous state or in methanol and yellow fluorescence in solid state. The N-alkylation of imidazole subunit(s) in 1 using n-propyl iodide generated unsymmetrically or symmetrically alkylated thiazolothiazolebridged imidazolium salts with good water solubility and remarkably strong emission in solution. Furthermore, the replacement of iodide counter-anion by triflate or bis(trifluoromethane sulfonyl)imide achieved remarkably strong emission in solid state and in solution as well as good water solubility. The strong fluorescence of dicationic salts with triflate and NTf_(2)^(-)counter-anions in solid state can be ascribed to their twisted and rigid structures induced by interionic C-H···F hydrogen bonding.
基金supported by grants from the National Natural Science Foundation of China(No.21702239)Guangzhou Science and Technology Plan Projects(No.201707010271)the Fundamental Research Funds for the Central Universities(No.16lgpy16)。
文摘To discover novel fluoro p hores of solution and solid dual-state emission(DSE) materials,unique V-shape furo[2,3-b]furans have been designed and synthesized by a one-pot method for the first time and their photoluminescent properties have been explored in benzene,THF,DMF and DMSO,as well as in the solid state.As the best example,2,5-bis(4-(9 H-carbazol-9-yl)phenyl)-6 a-amino-3 a,6 a-dihydrofuro[2,3-b]furan-3,3 a,4-trica rbonitrile(3 g) exhibited solution and solid DSE properties in THF,benzene,and in the solid state with quantum yields of 55%,92%,and 45%,respectively.
基金the generous financial support of the National Key R&D Program of China(grant no.2019YFA0210100)the National Natural Science Foundation of China(grant nos.21890744 and 21877029)+1 种基金the Hunan Postgraduate Research and Innovation Project(grant no.CX2018B187)the China Postdoctoral Science Foundation(grant nos.2019TQ0085 and 2020M682538).
文摘Developing dual-state luminophores(DSLs)with strong fluorescence in both the monomer and aggregate states is urgently needed but remains a huge challenge because most current luminophores are either aggregation-induced emission or aggregation-caused quenching molecules.Moreover,limited by the structural conservation of the few existing DSLs,there are not enough response sites that can be used to customize various activatable fluorescent probes for specific molecular imaging.Herein,we engineered a general integration strategy for the fabrication of such DSLs with excellent photophysical properties.The DSLs,with their tunable spectra,a large Stokes shift(>170 nm),and achievable near-infrared(NIR)emission,show great potential for high-contrast imaging.Importantly,DSLs can be used as a universal platform for probe customization due to their activatable fluorescence through protection-deprotection of the phenolic hydroxyl group.Based on this,an NIR fluorescent probe DSL-Gal was developed for sensing of β-galactosidase in solutions,senescent cells,and liver metastases with high contrast,further confirming the superiority and universal feasibility of DSLs in probe design.The integration strategy may provide a novel approach for the generation of other DSLs and have great potential applications in bioimaging.
基金supported by the National Natural Science Foundation of China (51673180, 51373162)
文摘A new dual-state emission(DSE) dye comprised of tetraphenylethene(TPE), triphenylamine(TPA), and indoline groups has been synthesized, which showed efficient fluorescence in both solution and solid. The dye is comprised of three parts and these parts show different fluorescence properties which can be very useful in some applications since the dye can produce information-rich responses. For example, the dye is p H-sensitive in both solution and solid states, and it emits yellow fluorescence in normal p H and red/NIR fluorescence in acidic condition. Cytotoxicity of the dye is low at concentration of 3 μM which was confirmed by a methyl thiazolyl tetrazolium(MTT) experiment, and in vitro experiments revealed that the p H responsive performance can be used in bioimaging. It provides a novel p H-sensitive DSE dye ever reported, which has potential application in many fields.
文摘In the multi-radar networking system,aiming at the problem of locating long-distance targets synergistically with difficulty and low accuracy,a dual-station joint positioning method based on the target measurement error feature complementarity is proposed.For dual-station joint positioning,by constructing the target positioning error distribution model and using the complementarity of spatial measurement errors of the same long-distance target,the area with high probability of target existence can be obtained.Then,based on the target distance information,the midpoint of the intersection between the target positioning sphere and the positioning tangent plane can be solved to acquire the target's optimal positioning result.The simulation demonstrates that this method greatly improves the positioning accuracy of target in azimuth direction.Compared with the traditional the dynamic weighted fusion(DWF)algorithm and the filter-based dynamic weighted fusion(FBDWF)algorithm,it not only effectively eliminates the influence of systematic error in the azimuth direction,but also has low computational complexity.Furthermore,for the application scenarios of multi-radar collaborative positioning and multi-sensor data compression filtering in centralized information fusion,it is recommended that using radar with higher ranging accuracy and the lengths of baseline between radars are 20–100 km.
