Objectives To evaluate the changes of the left ventricular form and function after closure of moderate- to large-sized patent ductus arteriosus （PDA） using domestic-made occluder. Methods 22 patients with PDA underw...Objectives To evaluate the changes of the left ventricular form and function after closure of moderate- to large-sized patent ductus arteriosus （PDA） using domestic-made occluder. Methods 22 patients with PDA underwent procedure successfuly using the domestic-made occluder. The mean PDA minimal （pulmonary end） diameter by aortography was 8.01±2.47 mm （range 4 to 15.5mm）. All patients underwent transthoracic echocardiography （TTE） study before the procedure and the following 48 hours, 3 months after procedure. Results All patients had been implanted the domestic-made occluders successfully with no haematolysis, infective endocarditis, recanalization and other complications. At 3 months, mean LVED was decreased to 50.05±6.55 mm, compared to the pre-procedure （55.67 ±8.48 mm）, P 〈 0.01. After 48 hours of the procedure, mean LVEDD and LVESD decreased significantly （156.22± 51.40 mL vs. 121.28±35.73ml, 57.16±32.07 mL vs. 45.88±15.97 mL）, P〈 0.05. At 3 months, LVEDD decreased to 110.93 ±15.08ml, LVSV reached 73.50± 9.19 mL, compared to the pre-procedure, P 〈 0.01. LVESD decreased to 37.43±10.44 mL at 3 months, P〈 0.05. Conclusions Closuring of moderate- to largesized PDA using domestic-made occluder is effective and safe. After procedure, left ventricular form and function improved.展开更多
基金Items of tackle key problems in science andtechnology, Guangxi (0472002-30)
文摘Objectives To evaluate the changes of the left ventricular form and function after closure of moderate- to large-sized patent ductus arteriosus （PDA） using domestic-made occluder. Methods 22 patients with PDA underwent procedure successfuly using the domestic-made occluder. The mean PDA minimal （pulmonary end） diameter by aortography was 8.01±2.47 mm （range 4 to 15.5mm）. All patients underwent transthoracic echocardiography （TTE） study before the procedure and the following 48 hours, 3 months after procedure. Results All patients had been implanted the domestic-made occluders successfully with no haematolysis, infective endocarditis, recanalization and other complications. At 3 months, mean LVED was decreased to 50.05±6.55 mm, compared to the pre-procedure （55.67 ±8.48 mm）, P 〈 0.01. After 48 hours of the procedure, mean LVEDD and LVESD decreased significantly （156.22± 51.40 mL vs. 121.28±35.73ml, 57.16±32.07 mL vs. 45.88±15.97 mL）, P〈 0.05. At 3 months, LVEDD decreased to 110.93 ±15.08ml, LVSV reached 73.50± 9.19 mL, compared to the pre-procedure, P 〈 0.01. LVESD decreased to 37.43±10.44 mL at 3 months, P〈 0.05. Conclusions Closuring of moderate- to largesized PDA using domestic-made occluder is effective and safe. After procedure, left ventricular form and function improved.
