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Symbolic Model Checking and Analysis for E-Commerce Protocol
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作者 文静华 张梅 李祥 《Journal of Electronic Science and Technology of China》 2005年第3期213-217,共5页
A new approach is proposed for analyzing non-repudiation and fairness of e-commerce protocols. The authentication e-mail protocol CMP1 is modeled as finite state machine and analyzed in two vital aspects- non-repudiat... A new approach is proposed for analyzing non-repudiation and fairness of e-commerce protocols. The authentication e-mail protocol CMP1 is modeled as finite state machine and analyzed in two vital aspects- non-repudiation and fairness using SME. As a result, the CMP1 protocol is not fair and we have improved it. This result shows that it is effective to analyze and check the new features of e-commerce protocols using SMV model checker. 展开更多
关键词 e-commerce protocols FAIRNESS symbolic model verification
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Optimistic fair exchange E-commerce protocol based on secret sharing 被引量:3
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作者 Ma Changshe Lei Feiyu Chen Kefei 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2006年第4期858-863,共6页
A key problem of electronic commerce (for short e-commerce) is fair exchange which guarantees that at the end of the transaction, either both parties involved in the trausaction receive each other's items or none d... A key problem of electronic commerce (for short e-commerce) is fair exchange which guarantees that at the end of the transaction, either both parties involved in the trausaction receive each other's items or none do. A non-interactive optimistic fair exchange e-commerce protocol model based on the publicly verifiable secret sharing is presented. The main idea of our exchange protocol is to interchange verifiable and recoverable keys of the symmetric encryption for participants' items. So it is especially suitable for exchange of large-size items. Furthermore, our protocol is efficient and simple as it does not need interactive proof system which has been adopted by a large quantity of previously proposed fair exchange protocols. Based on a modified (2,2) secret sharing scheme, a concrete non-interactive fair exchange e-commerce protocol is designed. 展开更多
关键词 e-commerce optimistic fair-exchange publicly verfiable secret sharing.
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Impacts of agri-food e-commerce on traditional wholesale industry:Evidence from China
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作者 Ruyi Yang Jifang Liu +2 位作者 Shanshan Cao Wei Sun Fantao Kong 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第4期1409-1428,共20页
Rapidly expanding studies investigate the effects of e-commerce on company operations in the retail market.However,the interaction between agri-food e-commerce(AEC)and the traditional agri-food wholesale industry(AWI)... Rapidly expanding studies investigate the effects of e-commerce on company operations in the retail market.However,the interaction between agri-food e-commerce(AEC)and the traditional agri-food wholesale industry(AWI)has not received enough attention in the existing literature.Based on the provincial panel data from 2013 to 2020 in China,this paper examines the effect of AEC on AWI,comprising three dimensions:digitalization(DIGITAL),agrifood e-commerce infrastructure and supporting services(AECI),and agri-food e-commerce economy(AECE).First,AWI and AEC are measured using an entropy-based combination of indicators.The results indicate that for China as a whole,AWI has remained practically unchanged,whereas AEC exhibits a significant rising trend.Second,the findings of the fixed-effect regression reveal that DIGITAL and AECE tend to raise AWI,whereas AECI negatively affects AWI.Third,threshold regression results indicate that AECI tends to diminish AWI with three-stage inhibitory intensity,which manifests as a first increase and then a drop in the inhibition degree.These results suggest that with the introduction of e-commerce for agricultural product circulation,digital development will have catfish effects that tend to stimulate the vitality of the conventional wholesale industry and promote technical progress.Furthermore,the traditional wholesale industry benefits financially from e-commerce even while it diverts part of the traditional wholesale circulation for agricultural products. 展开更多
关键词 agri-food e-commerce traditional wholesale industry panel threshold model dual-channel circulation
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Impact of BRICS Trade Facilitation on China's Exports Using Cross-Border E-Commerce
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作者 Longling LI Kaimei CHEN Zijian LONG 《Asian Agricultural Research》 2024年第5期1-7,共7页
With the rapid growth of the global digital economy, cross-border e-commerce, as an emerging form of trade, has gradually become a powerful engine to promote the development of global trade. BRICS is an important forc... With the rapid growth of the global digital economy, cross-border e-commerce, as an emerging form of trade, has gradually become a powerful engine to promote the development of global trade. BRICS is an important force in the global economy, and the progress of the BRICS countries' trade facilitation level has an important impact on the global trade environment. This paper conducts an in-depth study of the dynamic changes in BRICS trade facilitation from 2013 to 2022, and uses an extended gravity model to analyze the specific impact of this change on China's exports using cross-border e-commerce. The results show that although the BRICS countries have made some progress in trade facilitation, the overall level still needs to be improved, and there are obvious differences among member countries. However, the improvement of trade facilitation among BRICS countries has undoubtedly brought significant positive effects to China's exports using cross-border e-commerce. 展开更多
关键词 Trade facilitation BRICS Cross-border e-commerce Export trade
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Predicting Purchasing Behavior on E-Commerce Platforms: A Regression Model Approach for Understanding User Features that Lead to Purchasing
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作者 Abraham Jallah Balyemah Sonkarlay J. Y. Weamie +2 位作者 Jiang Bin Karmue Vasco Jarnda Felix Jwakdak Joshua 《International Journal of Communications, Network and System Sciences》 2024年第6期81-103,共23页
This research introduces a novel approach to improve and optimize the predictive capacity of consumer purchase behaviors on e-commerce platforms. This study presented an introduction to the fundamental concepts of the... This research introduces a novel approach to improve and optimize the predictive capacity of consumer purchase behaviors on e-commerce platforms. This study presented an introduction to the fundamental concepts of the logistic regression algorithm. In addition, it analyzed user data obtained from an e-commerce platform. The original data were preprocessed, and a consumer purchase prediction model was developed for the e-commerce platform using the logistic regression method. The comparison study used the classic random forest approach, further enhanced by including the K-fold cross-validation method. Evaluation of the accuracy of the model’s classification was conducted using performance indicators that included the accuracy rate, the precision rate, the recall rate, and the F1 score. A visual examination determined the significance of the findings. The findings suggest that employing the logistic regression algorithm to forecast customer purchase behaviors on e-commerce platforms can improve the efficacy of the approach and yield more accurate predictions. This study serves as a valuable resource for improving the precision of forecasting customers’ purchase behaviors on e-commerce platforms. It has significant practical implications for optimizing the operational efficiency of e-commerce platforms. 展开更多
关键词 e-commerce Platform Purchasing Behavior Prediction Logistic Regression Algorithm
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Research on Current Situation and Legal Regulation of Cosmetics Live Streaming E-commerce in China
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作者 Jiang Ying 《China Detergent & Cosmetics》 CAS 2024年第1期63-70,共8页
Analyze the compatibility between cosmetics and live streaming e-commerce from its own nature,marketing means and supply chain characteristics.According to the prominent problems,sort out the relationship between all ... Analyze the compatibility between cosmetics and live streaming e-commerce from its own nature,marketing means and supply chain characteristics.According to the prominent problems,sort out the relationship between all parties in the cosmetics live e-commerce industry chain.Combined with the latest regulatory policies of live streaming e-commerce and cosmetics,the responsibilities of different subjects in cosmetics live streaming e-commerce are summarized,and relevant suggestions and countermeasures are put forward for the standardization and development of live streaming e-commerce.Cosmetics brand owners are the first responsible persons for product quality.Anchors,as a mixed identity between intermediary,advertising spokesperson and operator,should bear stricter joint and several liability when recommending products related to consumers’health.If anchors fail to clearly identify themselves in the recommendation process,thus causing consumers to mistake them for the operator of the cosmetics,they should assume the obligations of the operator. 展开更多
关键词 COSMETICS live streaming e-commerce legal relationship responsibilities of parties
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How Does E-Commerce Policy Affect Consumption Disparities of Rural Households?-Evidence from China
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作者 Zhang Cheng Weng Xiyan 《China Economist》 2024年第4期107-128,共22页
In the context of China’s ongoing efforts to promote countryside revitalization and facilitate domestic economic circulation,it is of great significance to reduce the consumption disparity among rural households and ... In the context of China’s ongoing efforts to promote countryside revitalization and facilitate domestic economic circulation,it is of great significance to reduce the consumption disparity among rural households and unleash the consumption potential in the countryside.Based on data from China Family Panel Studies,this paper adopts a staggered difference-in-differences method to assess the impact of the e-commerce to enter rural areas on the consumption disparity among rural households.Findings:the comprehensive demonstration work of promoting e-commerce to enter rural areas has reduced the consumption disparity among rural households through the following mechanisms.Firstly,this policy initiative has mitigated the consumption-inhibiting effect on rural household consumption due to the local market size and external market accessibility by promoting the distribution of consumer goods to villages.Secondly,this policy initiative has also increased the agricultural income of rural households and reduced their consumption disparity by distributing farm produce to cities and enhancing the agricultural income of rural households.Moreover,the work is characterized by inclusive growth and is not susceptible to the“elite capture”phenomenon. 展开更多
关键词 e-commerce to enter rural areas consumption disparity among rural household market accessibility market size income of rural households
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The Impact of E-Commerce Live Broadcasts on Consumers’Purchase Intention
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作者 Xingchao Bian Thanakon Ratchatakulpat Rattanavalee Maisak 《Proceedings of Business and Economic Studies》 2024年第4期263-268,共6页
E-commerce live broadcast has an important influence on consumers’purchase intention.The three dimensions of live broadcast content in the broadcast room are the number of comments,product quality,and live content as... E-commerce live broadcast has an important influence on consumers’purchase intention.The three dimensions of live broadcast content in the broadcast room are the number of comments,product quality,and live content as independent variables.A theoretical model is constructed with perceived value and risk as intermediaries and the consumers’purchase intention as the dependent variable,and corresponding hypotheses are put forward.We designed the scale,collected relevant data,and tested the model hypothesis using Statistical Package for Social Sciences(SPSS)and Analysis of Moment Structure(AMOS)software.The study found that the number of comments and product quality had a significant impact on perceived value,perceived risk,and consumers’purchase intention.From this conclusion,it is suggested that businesses should control the number of comments,strengthen the product quality of comments,and distinguish the repetition degree of the content of live broadcasts. 展开更多
关键词 Livestreaming e-commerce Perceived value Perceived risk Purchase intention
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Analysis of the Current Situation, Influential Factors, and Countermeasures of Rural E-commerce Development
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作者 Yi Wei Guizhen He 《Journal of Electronic Research and Application》 2024年第2期140-145,共6页
The development of rural e-commerce is becoming an important driver for the transformation of China’s rural economy,and with the rapid development of information technology and the upgrading of the agricultural indus... The development of rural e-commerce is becoming an important driver for the transformation of China’s rural economy,and with the rapid development of information technology and the upgrading of the agricultural industry,rural e-commerce is showing a vigorous momentum of development.Traditionally,agricultural products are mainly sold through traditional farmers’markets,which are subjected to geography and channel limitations,resulting in inefficient circulation of agricultural products.This paper analyzes the definition,the status quo,as well as the influencing factors of rural e-commerce development.On this basis,countermeasures for the advancement of rural e-commerce development are put forward. 展开更多
关键词 Rural e-commerce Influencing factors Industrial clusters RESPONSE
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Research on Professional Teaching Reform of the E-Commerce Major in Vocational Colleges Under the Internet Era
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作者 Yong Liang 《Journal of Contemporary Educational Research》 2024年第5期21-26,共6页
With the rapid development of science and technology,the face of human society has undergone great changes;with the emergence of the Internet era,all kinds of educational technology,equipment,and software in vocationa... With the rapid development of science and technology,the face of human society has undergone great changes;with the emergence of the Internet era,all kinds of educational technology,equipment,and software in vocational colleges have been widely used to carry out education and teaching,and has achieved remarkable results.Based on this,colleges and universities’electronic commerce(e-commerce)professional teachers should try to rely on the Internet to build information teaching classrooms,introduce advanced methods to build efficient classrooms by integrating teaching resources,and optimize the top-level design,so as to activate the classroom atmosphere,mobilize students’emotions,make them immersed in the teaching of electronic commerce courses.In view of this,this paper combines the existing theory and experience,first analyzes the dilemma faced by the current teaching of e-commerce in vocational colleges,then discusses the practical significance of teaching reform based on the Internet era,and lastly puts forward the specific practice path. 展开更多
关键词 INTERNET Vocational colleges e-commerce major Teaching reform
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Optimization and Innovation of the Operation Model of Mobile Social E-commerce under AI Empowerment:Taking the Female Community Platform“Little Red Book”as an Example
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作者 Mi Liu Jia Yu +1 位作者 Yan Li Jun Zheng 《Proceedings of Business and Economic Studies》 2024年第4期269-274,共6页
This article takes the female community platform“Little Red Book”as an example to explore the optimization and innovation of mobile community e-commerce operation mode under Artificial Intelligence(AI)empowerment.Fi... This article takes the female community platform“Little Red Book”as an example to explore the optimization and innovation of mobile community e-commerce operation mode under Artificial Intelligence(AI)empowerment.Firstly,the relevant concepts were defined,and then the unique attributes of mobile community e-commerce were analyzed.As a typical representative of mobile community e-commerce,Little Red Book introduces the background and characteristics of its platform,analyzes its mobile community operation mode,and focuses on exploring how to establish a mobile community e-commerce platform and effective operation mode under the empowerment of AI technology,to provide some reference and inspiration for the development and operation of Little Red Book and other e-commerce platform enterprises. 展开更多
关键词 Mobile social e-commerce Little Red Book Female community platform AI User experience UGC
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Spatial Structure of China's E-commerce Express Logistics Network Based on Space of Flows 被引量:3
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作者 LI Yuanjun WU Qitao +2 位作者 ZHANG Yuling HUANG Guangqing ZHANG Hongou 《Chinese Geographical Science》 SCIE CSCD 2023年第1期36-50,共15页
The intermediate link compression characteristics of e-commerce express logistics ne tworks influence the tradition al mode of circulation of goods and economic organization,and alter the city spatial pattern.Based on... The intermediate link compression characteristics of e-commerce express logistics ne tworks influence the tradition al mode of circulation of goods and economic organization,and alter the city spatial pattern.Based on the theory of space of flows,this study adopts China Smart Logistics Network relational data to build China's e-commerce express logistics network and explore its spatial structure characteristics through social network analysis(SNA),the PageRank technique,and geospatial methods.The results are as follows:the network density is 0.9270,which is close to 1;hence,indicating that e-commerce express logistics lines between Chinese cities are nearly complete and they form a typical network structure,thereby eliminating fragmented spaces.Moreover,the average minimum number of edges is 1.1375,which indicates that the network has a small world effect and thus has a high flow efficiency of logistics elements.A significant hierarchical diffusion effect was observed in dominant flows with the highest edge weights.A diamond-structured network was formed with Shanghai,Guangzhou,Chongqing,and Beijing as the four core nodes.Other node cities with a large logistics scale and importance in the network are mainly located in the 19 city agglomerations of China,revealing the fact that the development of city agglomerations is essential for promoting the separation of experience space and changing the urban spatial pattern.This study enriches the theory of urban networks,reveals the flow laws of modern logistics elements,and encourages coordinated development of urban logistics. 展开更多
关键词 space of flows e-commerce express logistics urban logistics network logistics big data
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Safety and effectiveness of butorphanol in epidural labor analgesia:A protocol for a systematic review and meta-analysis 被引量:3
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作者 Guan-Cheng Tang Man He +1 位作者 Zhen-Zhao Huang Yan Cheng 《World Journal of Clinical Cases》 SCIE 2024年第8期1416-1421,共6页
BACKGROUND Epidural analgesia is the most effective analgesic method during labor.Butorphanol administered epidurally has been shown to be a successful analgesic method during labor.However,no comprehensive study has ... BACKGROUND Epidural analgesia is the most effective analgesic method during labor.Butorphanol administered epidurally has been shown to be a successful analgesic method during labor.However,no comprehensive study has examined the safety and efficacy of using butorphanol as an epidural analgesic during labor.AIM To assess butorphanol's safety and efficacy for epidural labor analgesia.METHODS The PubMed,Cochrane Library,EMBASE,Web of Science,China National Knowledge Infrastructure,and Google Scholar databases will be searched from inception.Other types of literature,such as conference abstracts and references to pertinent reviews,will also be reviewed.We will include randomized controlled trials comparing butorphanol with other opioids combined with local anesthetics for epidural analgesia during labor.There will be no language restrictions.The primary outcomes will include the visual analog scale score for the first stage of labor,fetal effects,and Apgar score.Two independent reviewers will evaluate the full texts,extract data,and assess the risk of bias.Publication bias will be evaluated using Egger's or Begg's tests as well as visual analysis of a funnel plot,and heterogeneity will be evaluated using the Cochran Q test,P values,and I2 values.Meta-analysis,subgroup analysis,and sensitivity analysis will be performed using RevMan software version 5.4.This protocol was developed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)Protocols statement,and the PRISMA statement will be used for the systematic review.RESULTS This study provides reliable information regarding the safety and efficacy of using butorphanol as an epidural analgesic during labor.CONCLUSION To support clinical practice and development,this study provides evidence-based findings regarding the safety and efficacy of using butorphanol as an epidural analgesic during labor. 展开更多
关键词 Epidural analgesia during labor BUTORPHANOL SAFETY protocol META-ANALYSIS
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Transaction Frequency Based Trust for E-Commerce
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作者 Dong Huang Sean Xu 《Computers, Materials & Continua》 SCIE EI 2023年第3期5319-5329,共11页
Most traditional trust computing models in E-commerce do not take the transaction frequency among participating entities into consideration,which makes it easy for one party of the transaction to obtain a high trust v... Most traditional trust computing models in E-commerce do not take the transaction frequency among participating entities into consideration,which makes it easy for one party of the transaction to obtain a high trust value in a short time,and brings many disadvantages,uncertainties and even attacks.To solve this problem,a transaction frequency based trust is proposed in this study.The proposed method is composed of two parts.The first part is built on the classic Bayes analysis based trust modelswhich are ease of computing for the E-commerce system.The second part is the transaction frequency module which can mitigate the potential insecurity caused by one participating entity gaining trust in a short time.Simulations show that the proposed method can effectively mitigate the self-promoting attacks so as to maintain the function of E-commerce system. 展开更多
关键词 Transaction frequency TRUST Bayes analysis e-commerce
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Enhanced E-commerce Fraud Prediction Based on a Convolutional Neural Network Model
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作者 Sumin Xie Ling Liu +3 位作者 Guang Sun Bin Pan Lin Lang Peng Guo 《Computers, Materials & Continua》 SCIE EI 2023年第4期1107-1117,共11页
The rapidly escalating sophistication of e-commerce fraud in recent years has led to an increasing reliance on fraud detection methods based on machine learning.However,fraud detection methods based on conventional ma... The rapidly escalating sophistication of e-commerce fraud in recent years has led to an increasing reliance on fraud detection methods based on machine learning.However,fraud detection methods based on conventional machine learning approaches suffer from several problems,including an excessively high number of network parameters,which decreases the efficiency and increases the difficulty of training the network,while simultaneously leading to network overfitting.In addition,the sparsity of positive fraud incidents relative to the overwhelming proportion of negative incidents leads to detection failures in trained networks.The present work addresses these issues by proposing a convolutional neural network(CNN)framework for detecting ecommerce fraud,where network training is conducted using historical market transaction data.The number of network parameters reduces via the local perception field and weight sharing inherent in the CNN framework.In addition,this deep learning framework enables the use of an algorithmiclevel approach to address dataset imbalance by focusing the CNN model on minority data classes.The proposed CNN model is trained and tested using a large public e-commerce service dataset from 2018,and the test results demonstrate that the model provides higher fraud prediction accuracy than existing state-of-the-art methods. 展开更多
关键词 CNN model detection e-commerce FRAUD
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Falcon Optimization Algorithm-Based Energy Efficient Communication Protocol for Cluster-Based Vehicular Networks 被引量:1
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作者 Youseef Alotaibi B.Rajasekar +1 位作者 R.Jayalakshmi Surendran Rajendran 《Computers, Materials & Continua》 SCIE EI 2024年第3期4243-4262,共20页
Rapid development in Information Technology(IT)has allowed several novel application regions like large outdoor vehicular networks for Vehicle-to-Vehicle(V2V)transmission.Vehicular networks give a safe and more effect... Rapid development in Information Technology(IT)has allowed several novel application regions like large outdoor vehicular networks for Vehicle-to-Vehicle(V2V)transmission.Vehicular networks give a safe and more effective driving experience by presenting time-sensitive and location-aware data.The communication occurs directly between V2V and Base Station(BS)units such as the Road Side Unit(RSU),named as a Vehicle to Infrastructure(V2I).However,the frequent topology alterations in VANETs generate several problems with data transmission as the vehicle velocity differs with time.Therefore,the scheme of an effectual routing protocol for reliable and stable communications is significant.Current research demonstrates that clustering is an intelligent method for effectual routing in a mobile environment.Therefore,this article presents a Falcon Optimization Algorithm-based Energy Efficient Communication Protocol for Cluster-based Routing(FOA-EECPCR)technique in VANETS.The FOA-EECPCR technique intends to group the vehicles and determine the shortest route in the VANET.To accomplish this,the FOA-EECPCR technique initially clusters the vehicles using FOA with fitness functions comprising energy,distance,and trust level.For the routing process,the Sparrow Search Algorithm(SSA)is derived with a fitness function that encompasses two variables,namely,energy and distance.A series of experiments have been conducted to exhibit the enhanced performance of the FOA-EECPCR method.The experimental outcomes demonstrate the enhanced performance of the FOA-EECPCR approach over other current methods. 展开更多
关键词 Vehicular networks communication protocol CLUSTERING falcon optimization algorithm ROUTING
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An Enhanced Intelligent Intrusion Detection System to Secure E-Commerce Communication Systems
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作者 Adil Hussain Kashif Naseer Qureshi +1 位作者 Khalid Javeed Musaed Alhussein 《Computer Systems Science & Engineering》 SCIE EI 2023年第11期2513-2528,共16页
Information and communication technologies are spreading rapidly due to their fast proliferation in many fields.The number of Internet users has led to a spike in cyber-attack incidents.E-commerce applications,such as... Information and communication technologies are spreading rapidly due to their fast proliferation in many fields.The number of Internet users has led to a spike in cyber-attack incidents.E-commerce applications,such as online banking,marketing,trading,and other online businesses,play an integral role in our lives.Network Intrusion Detection System(NIDS)is essential to protect the network from unauthorized access and against other cyber-attacks.The existing NIDS systems are based on the Backward Oracle Matching(BOM)algorithm,which minimizes the false alarm rate and causes of high packet drop ratio.This paper discussed the existing NIDS systems and different used pattern-matching techniques regarding their weaknesses and limitations.To address the existing system issues,this paper proposes an enhanced version of the BOM algorithm by using multiple pattern-matching methods for the NIDS system to improve the network performance.The proposed solution is tested in simulation with existing solutions using the Snort and NSL-KDD datasets.The experimental results indicated that the proposed solution performed better than the existing solutions and achieved a 5.17%detection rate and a 0.22%lower false alarm rate than the existing solution. 展开更多
关键词 e-commerce NIDS security algorithm network applications CIA detection
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Cell replacement with stem cell-derived retinal ganglion cells from different protocols 被引量:1
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作者 Ziming Luo Kun-Che Chang 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第4期807-810,共4页
Glaucoma,characterized by a degenerative loss of retinal ganglion cells,is the second leading cause of blindness worldwide.There is currently no cure for vision loss in glaucoma because retinal ganglion cells do not r... Glaucoma,characterized by a degenerative loss of retinal ganglion cells,is the second leading cause of blindness worldwide.There is currently no cure for vision loss in glaucoma because retinal ganglion cells do not regenerate and are not replaced after injury.Human stem cell-derived retinal ganglion cell transplant is a potential therapeutic strategy for retinal ganglion cell degenerative diseases.In this review,we first discuss a 2D protocol for retinal ganglion cell differentiation from human stem cell culture,including a rapid protocol that can generate retinal ganglion cells in less than two weeks and focus on their transplantation outcomes.Next,we discuss using 3D retinal organoids for retinal ganglion cell transplantation,comparing cell suspensions and clusters.This review provides insight into current knowledge on human stem cell-derived retinal ganglion cell differentiation and transplantation,with an impact on the field of regenerative medicine and especially retinal ganglion cell degenerative diseases such as glaucoma and other optic neuropathies. 展开更多
关键词 cell clumps cell suspension cell transplantation DIFFERENTIATION direct-induced protocol GLAUCOMA optic neuropathy regenerative medicine retinal ganglion cell retinal organoids stem cells
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Corneal collagen cross-linking in patients with keratoconus from the Dresden protocol to customized solutions:theoretical basis
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作者 Ciro Caruso Luca D’Andrea +4 位作者 Mario Troisi Michele Rinaldi Raffaele Piscopo Salvatore Troisi Ciro Costagliola 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第5期951-962,共12页
Keratoconus is an ectatic condition characterized by gradual corneal thinning,corneal protrusion,progressive irregular astigmatism,corneal fibrosis,and visual impairment.The therapeutic options regarding improvement o... Keratoconus is an ectatic condition characterized by gradual corneal thinning,corneal protrusion,progressive irregular astigmatism,corneal fibrosis,and visual impairment.The therapeutic options regarding improvement of visual function include glasses or soft contact lenses correction for initial stages,gas-permeable rigid contact lenses,scleral lenses,implantation of intrastromal corneal ring or corneal transplants for most advanced stages.In keratoconus cases showing disease progression corneal collagen crosslinking(CXL)has been proven to be an effective,minimally invasive and safe procedure.CXL consists of a photochemical reaction of corneal collagen by riboflavin stimulation with ultraviolet A radiation,resulting in stromal crosslinks formation.The aim of this review is to carry out an examination of CXL methods based on theoretical basis and mathematical models,from the original Dresden protocol to the most recent developments in the technique,reporting the changes proposed in the last 15y and examining the advantages and disadvantages of the various treatment protocols.Finally,the limits of non-standardized methods and the perspectives offered by a customization of the treatment are highlighted. 展开更多
关键词 corneal collagen cross linking KERATOCONUS custom fast protocol Dresden protocol lambert-beer law Bunsen-roscoe law
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Home Monitoring of Estrone-3-Glucuronide (E1-3G) Levels in Two Different Ovarian Stimulation Protocols: A Pilot Study
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作者 Iavor K. Vladimirov Desislava Tacheva +2 位作者 Evan Gatev Magdalena Rangelova Martin Vladimirov 《Open Journal of Obstetrics and Gynecology》 2024年第10期1640-1656,共17页
Background: Studies have shown a strong correlation between the growth of E2 in serum and estrone-3-glucuronide (E1-3G) in urine during ovarian stimulation. Thus, we developed theoretical models for using urinary E1-3... Background: Studies have shown a strong correlation between the growth of E2 in serum and estrone-3-glucuronide (E1-3G) in urine during ovarian stimulation. Thus, we developed theoretical models for using urinary E1-3G in ovarian stimulation and focused on their experimental verification and analysis. Methods: A prospective, observational pilot study was conducted involving 54 patients who underwent 54 cycles of ovarian stimulation. The goal was to establish the growth rate of urinary E1-3G during the course of stimulation and to determine the daily upper and lower limits of growth rates at which stimulation is appropriate and safe. Controlled ovarian stimulation was performed using two different stimulation protocols—an antagonist protocol in 25 cases and a progestin-primed ovarian stimulation protocol (PPOS) in 29 cases, with fixed doses of gonadotropins. From the second day of stimulation, patients self-measured their daily urine E1-3G levels at home using a portable analyzer. In parallel, a standard ultrasound follow-up protocol accompanied by a determination of E2, LH, and P levels was applied to optimally control stimulation. Results: The average daily growth rates in both groups were about 50%. The daily increase in E1-3G for the antagonist protocol ranged from 14% to 79%, while they were 28% to 79% for the PPOS protocol. Conclusion: This is the first study to analyze the dynamics of E1-3G in two different protocols and to estimate the limits of its increase during the entire course of the stimulation. The results confirm our theoretical model for the viability of using urinary E1-3G for monitoring ovarian stimulation. 展开更多
关键词 Ovarian Stimulation Monitoring E1-3G Antagonist protocol PPOS protocol IVF ART
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