Alongside clinical achievements,experiments conducted on animal models (including primate or non-primate) have been effective in the understanding of various pathophysiological aspects of perinatal hypoxic/ ischemic e...Alongside clinical achievements,experiments conducted on animal models (including primate or non-primate) have been effective in the understanding of various pathophysiological aspects of perinatal hypoxic/ ischemic encephalopathy (HIE).Due to the reasonably fair degree of flexibility with experiments,most of the research around HIE in the literature has been largely concerned with the neurodevelopmental outcome or how the frequency and duration of HI seizures could relate to the severity of perinatal brain injury,following HI insult.This survey concentrates on how EEG experimental studies using asphyxiated animal models (in rodents,piglets,sheep and non-human primate monkeys) provide a unique opportunity to examine from the exact time of HI event to help gain insights into HIE where human studies become difficult.展开更多
Emotions serve various functions.The traditional emotion recognition methods are based primarily on readily accessible facial expressions,gestures,and voice signals.However,it is often challenging to ensure that these...Emotions serve various functions.The traditional emotion recognition methods are based primarily on readily accessible facial expressions,gestures,and voice signals.However,it is often challenging to ensure that these non-physical signals are valid and reliable in practical applications.Electroencephalogram(EEG)signals are more successful than other signal recognition methods in recognizing these characteristics in real-time since they are difficult to camouflage.Although EEG signals are commonly used in current emotional recognition research,the accuracy is low when using traditional methods.Therefore,this study presented an optimized hybrid pattern with an attention mechanism(FFT_CLA)for EEG emotional recognition.First,the EEG signal was processed via the fast fourier transform(FFT),after which the convolutional neural network(CNN),long short-term memory(LSTM),and CNN-LSTM-attention(CLA)methods were used to extract and classify the EEG features.Finally,the experiments compared and analyzed the recognition results obtained via three DEAP dataset models,namely FFT_CNN,FFT_LSTM,and FFT_CLA.The final experimental results indicated that the recognition rates of the FFT_CNN,FFT_LSTM,and FFT_CLA models within the DEAP dataset were 87.39%,88.30%,and 92.38%,respectively.The FFT_CLA model improved the accuracy of EEG emotion recognition and used the attention mechanism to address the often-ignored importance of different channels and samples when extracting EEG features.展开更多
Purpose: Implant therapy restores masticatory function by restoring lost tooth morphology. It has been shown that mastication contributes not only to food intake and digestion, but also to the improvement of overall h...Purpose: Implant therapy restores masticatory function by restoring lost tooth morphology. It has been shown that mastication contributes not only to food intake and digestion, but also to the improvement of overall health. However, there have been no studies on the effects of implant treatment on electroencephalography (EEG). In this study, we investigated the effects of restoration of masticatory function by implant treatment on EEG and stress. Methods: 13 subjects (6 males, 7 females, age 64.1 ± 5.8 years) who had lost masticatory function due to tooth loss and 11 healthy subjects (6 males, 5 females, age 47.6 ± 2.4 years) as a control group. EEG (θ, α, β waves, α/β ratio) and salivary cortisol were measured before immediate dental implant treatment and every month of treatment for 6 months. EEG (θ, α, β waves, α/β ratio) was measured with a simple electroencephalograph miniature DAQ terminal (Intercross-410, Intercross Co., Ltd., Japan) in a resting closed-eye condition, and salivary cortisol was measured using an ELISA kit. Results: Compared to the control group, the appearance of θ and α waves were significantly decreased and β waves were increased, and α/β ratio was significantly decreased. The cortisol level of the subject group was significantly higher compared with the control group. With the course of implant treatment, the appearance of θ and α waves of the subject group increased, while β waves decreased. However, no significant difference was observed. The α/β ratio of the subject group increased from the first month after implant treatment and increased significantly after 5 and 6 months (0 vs. 5 months: p < 0.05, 0 vs. 6 months: p < 0.01). The cortisol levels in the subject group decreased from the first month after implant treatment and significantly decreased after 3 or 4 months (0 vs. 3 months: p < 0.05, 0 vs. 4 months: p < 0.01). These results suggest that tooth loss causes mental stress, which decreases brain stimulation and affects function. Restoration of masticatory function by implants was suggested to alleviate the effects on brain function and stress.展开更多
基金supported by the Auckland Medical Research Foundation,No.1117017(to CPU)
文摘Alongside clinical achievements,experiments conducted on animal models (including primate or non-primate) have been effective in the understanding of various pathophysiological aspects of perinatal hypoxic/ ischemic encephalopathy (HIE).Due to the reasonably fair degree of flexibility with experiments,most of the research around HIE in the literature has been largely concerned with the neurodevelopmental outcome or how the frequency and duration of HI seizures could relate to the severity of perinatal brain injury,following HI insult.This survey concentrates on how EEG experimental studies using asphyxiated animal models (in rodents,piglets,sheep and non-human primate monkeys) provide a unique opportunity to examine from the exact time of HI event to help gain insights into HIE where human studies become difficult.
基金This work was supported by the National Nature Science Foundation of China(No.61503423,H.P.Jiang).The URL is http://www.nsfc.gov.cn/.
文摘Emotions serve various functions.The traditional emotion recognition methods are based primarily on readily accessible facial expressions,gestures,and voice signals.However,it is often challenging to ensure that these non-physical signals are valid and reliable in practical applications.Electroencephalogram(EEG)signals are more successful than other signal recognition methods in recognizing these characteristics in real-time since they are difficult to camouflage.Although EEG signals are commonly used in current emotional recognition research,the accuracy is low when using traditional methods.Therefore,this study presented an optimized hybrid pattern with an attention mechanism(FFT_CLA)for EEG emotional recognition.First,the EEG signal was processed via the fast fourier transform(FFT),after which the convolutional neural network(CNN),long short-term memory(LSTM),and CNN-LSTM-attention(CLA)methods were used to extract and classify the EEG features.Finally,the experiments compared and analyzed the recognition results obtained via three DEAP dataset models,namely FFT_CNN,FFT_LSTM,and FFT_CLA.The final experimental results indicated that the recognition rates of the FFT_CNN,FFT_LSTM,and FFT_CLA models within the DEAP dataset were 87.39%,88.30%,and 92.38%,respectively.The FFT_CLA model improved the accuracy of EEG emotion recognition and used the attention mechanism to address the often-ignored importance of different channels and samples when extracting EEG features.
文摘Purpose: Implant therapy restores masticatory function by restoring lost tooth morphology. It has been shown that mastication contributes not only to food intake and digestion, but also to the improvement of overall health. However, there have been no studies on the effects of implant treatment on electroencephalography (EEG). In this study, we investigated the effects of restoration of masticatory function by implant treatment on EEG and stress. Methods: 13 subjects (6 males, 7 females, age 64.1 ± 5.8 years) who had lost masticatory function due to tooth loss and 11 healthy subjects (6 males, 5 females, age 47.6 ± 2.4 years) as a control group. EEG (θ, α, β waves, α/β ratio) and salivary cortisol were measured before immediate dental implant treatment and every month of treatment for 6 months. EEG (θ, α, β waves, α/β ratio) was measured with a simple electroencephalograph miniature DAQ terminal (Intercross-410, Intercross Co., Ltd., Japan) in a resting closed-eye condition, and salivary cortisol was measured using an ELISA kit. Results: Compared to the control group, the appearance of θ and α waves were significantly decreased and β waves were increased, and α/β ratio was significantly decreased. The cortisol level of the subject group was significantly higher compared with the control group. With the course of implant treatment, the appearance of θ and α waves of the subject group increased, while β waves decreased. However, no significant difference was observed. The α/β ratio of the subject group increased from the first month after implant treatment and increased significantly after 5 and 6 months (0 vs. 5 months: p < 0.05, 0 vs. 6 months: p < 0.01). The cortisol levels in the subject group decreased from the first month after implant treatment and significantly decreased after 3 or 4 months (0 vs. 3 months: p < 0.05, 0 vs. 4 months: p < 0.01). These results suggest that tooth loss causes mental stress, which decreases brain stimulation and affects function. Restoration of masticatory function by implants was suggested to alleviate the effects on brain function and stress.