针刺对老年痴呆大鼠海马、皮层电图的影响

目的 :探讨针刺对老年痴呆大鼠海马、皮层电图的影响。方法 :采用腹腔注射东莨菪碱造成记忆损伤的“老年痴呆”模型 ,按照整合生物学的观点进行活体记录海马、皮层电活动变化。结果 :注射东莨菪碱后 ,大鼠海马、皮层电活动受到抑制 ,从注射后 15min起与注射前比较 ,均有极显著性差异 (P <0 0 1) ;但针刺后频率持续回升 ,海马电图在针后 15min及 2 0minEHG与模型组比较有显著性差异 (P <0 0 5 ) ,皮层电图在针后 5min与模型组比较有显著性差异 (P <0 0 5 ) ,针后10、15、2 0min与模型组比较有极显著性差异 (P <0 0 1)。结论 :针刺对老年痴呆海马、皮层电活动有一定程度的兴奋效应。

Enhancement of Spatial Learning-Memory in Developing Rats via Mozart Music

This paper studies the effect of musical stimulations on the capability of the spatial learningmemory in developing rats by behavioral and electrophysiological techniques. Rats, which are exposed to Mozart＇s Sonata for Two Pianos in D Major, complete learning tasks of the Moriss water maze with significantly shorter latencies, and the power spectrum of alpha band of electrohippocampogram （EHG） significantly increase, compared with the control rats and rats exposed to the horror music. The results indicate that if given the stimulation of Mozart music in the developmental period of the auditory cortex, the capability of the spatial learning-memory can be significantly changed. The enhancement of alpha band of EHG may be related to the change of this function mainly.