Objective: The purpose of this study is to investigate whether the LE CAT, PROMIS PF CAT, Depression CAT, or Pain CAT can be used as a proxy for the EQ-5D-5L. Background: Patient-reported out-come measures have become...Objective: The purpose of this study is to investigate whether the LE CAT, PROMIS PF CAT, Depression CAT, or Pain CAT can be used as a proxy for the EQ-5D-5L. Background: Patient-reported out-come measures have become vital tools for physicians to understand the effectiveness and value of treatment and care. Methods: This study was conducted in 2012 with 116 patients that took the EQ-5D-5L and a number of patient-reported outcome instruments in a university orthopaedic clinic. Regression analyses were conducted to predict EQ-5D-5L index scores from the LE CAT, PROMIS PF CAT, Depression CAT, and Pain CAT. Results: All predictors, separately or combined, significantly predicted the EQ-5D-5L index scores (p < 0.0001). The LE CAT was the best predictor;it alone accounted for 37% of the variability in the EQ-5D-5L. When combining patient-reported outcome measures, the best predicting model was the one consisting of the LE CAT, Depression CAT and Pain CAT;they explained for 43.9% of the variance in EQ-5D-5L. Conclusions: The findings provide encouraging news that the LE CAT, PF CAT, Depression CAT and Pain CAT can be used alone or in combination as a proxy for the EQ-5D-5L. Researchers have the options of using these patient-reported outcome measures for economic evaluations and medical intervention studies.展开更多
目的探究社会资本对慢性非传染性疾病患者生命质量的影响。方法本研究采用多阶段分层整群抽样方法抽取调查对象,由经过专业培训的调查员入户面对面进行问卷调查,采用五维五水平生存质量量表(European Quality of Life Five Dimension Fi...目的探究社会资本对慢性非传染性疾病患者生命质量的影响。方法本研究采用多阶段分层整群抽样方法抽取调查对象,由经过专业培训的调查员入户面对面进行问卷调查,采用五维五水平生存质量量表(European Quality of Life Five Dimension Five Level Scale Questionnaire,EQ-5D-5L)和自制社会资本量表调查其生命质量和社会资本情况。运用因子分析和Cronbach’sα系数检验自编社会资本量表信效度,χ2检验和Tobit回归模型分析社会资本对慢性非传染性疾病患者生命质量的影响。结果本研究自编的社会资本量表性能良好,Cronbach’sα系数为0.728,KMO值为0.716,Bartlett球形检验的结果为P<0.001,说明该数据适合使用因子分析。4个公因子累计解释了总变异的68.27%。调查对象的健康效用值为(0.869±0.181),能四处走动、自己洗澡穿衣和进行日常活动中完全没问题的调查对象占75.70%、80.10%和74.1%,疼痛或不舒服和焦虑或沮丧自觉没有任何困难的分别占43.40%和58.90%;EQ-5D-5L量表中躯体健康维度的自评健康影响因素为社区安全和人际网络关系,社会功能健康的影响因素为社区安全,精神健康受到社区安全、社区信任和人际网络关系的影响;社区安全提高一个等级,慢性非传染性疾病患者健康效用值增加0.046,人际网络关系增加一个等级,健康效用值增加0.037。结论慢性非传染性疾病患者的生命质量主要问题表现在精神健康维度,在治疗过程中应注重心理疏导,社区安全和人际网络关系是患者自评健康的保护因素,提供安全的社区环境,扩大人际网络改善人际关系有助于提高患者健康水平。展开更多
基金国家自然科学基金青年基金项目“农村地区2型糖尿病Markov模型构建及相关干预策略经济学评价”(7143004)加拿大Lupina基金资助项目“Social derterminants of health in rural Anhui and the policy implications research”
文摘Objective: The purpose of this study is to investigate whether the LE CAT, PROMIS PF CAT, Depression CAT, or Pain CAT can be used as a proxy for the EQ-5D-5L. Background: Patient-reported out-come measures have become vital tools for physicians to understand the effectiveness and value of treatment and care. Methods: This study was conducted in 2012 with 116 patients that took the EQ-5D-5L and a number of patient-reported outcome instruments in a university orthopaedic clinic. Regression analyses were conducted to predict EQ-5D-5L index scores from the LE CAT, PROMIS PF CAT, Depression CAT, and Pain CAT. Results: All predictors, separately or combined, significantly predicted the EQ-5D-5L index scores (p < 0.0001). The LE CAT was the best predictor;it alone accounted for 37% of the variability in the EQ-5D-5L. When combining patient-reported outcome measures, the best predicting model was the one consisting of the LE CAT, Depression CAT and Pain CAT;they explained for 43.9% of the variance in EQ-5D-5L. Conclusions: The findings provide encouraging news that the LE CAT, PF CAT, Depression CAT and Pain CAT can be used alone or in combination as a proxy for the EQ-5D-5L. Researchers have the options of using these patient-reported outcome measures for economic evaluations and medical intervention studies.
文摘目的探究社会资本对慢性非传染性疾病患者生命质量的影响。方法本研究采用多阶段分层整群抽样方法抽取调查对象,由经过专业培训的调查员入户面对面进行问卷调查,采用五维五水平生存质量量表(European Quality of Life Five Dimension Five Level Scale Questionnaire,EQ-5D-5L)和自制社会资本量表调查其生命质量和社会资本情况。运用因子分析和Cronbach’sα系数检验自编社会资本量表信效度,χ2检验和Tobit回归模型分析社会资本对慢性非传染性疾病患者生命质量的影响。结果本研究自编的社会资本量表性能良好,Cronbach’sα系数为0.728,KMO值为0.716,Bartlett球形检验的结果为P<0.001,说明该数据适合使用因子分析。4个公因子累计解释了总变异的68.27%。调查对象的健康效用值为(0.869±0.181),能四处走动、自己洗澡穿衣和进行日常活动中完全没问题的调查对象占75.70%、80.10%和74.1%,疼痛或不舒服和焦虑或沮丧自觉没有任何困难的分别占43.40%和58.90%;EQ-5D-5L量表中躯体健康维度的自评健康影响因素为社区安全和人际网络关系,社会功能健康的影响因素为社区安全,精神健康受到社区安全、社区信任和人际网络关系的影响;社区安全提高一个等级,慢性非传染性疾病患者健康效用值增加0.046,人际网络关系增加一个等级,健康效用值增加0.037。结论慢性非传染性疾病患者的生命质量主要问题表现在精神健康维度,在治疗过程中应注重心理疏导,社区安全和人际网络关系是患者自评健康的保护因素,提供安全的社区环境,扩大人际网络改善人际关系有助于提高患者健康水平。
