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FOXO3-engineered human ESC-derived vascular cells promote vascular protection and regeneration 被引量:2
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《Science Foundation in China》 CAS 2019年第1期34-34,共1页
With the support by the National Natural Science Foundation of China and the Chinese Academy of Sciences,the research team led by Prof.Liu GuangHui(刘光慧)at the CAS National Laboratory of Biomacromolecules,Institute ... With the support by the National Natural Science Foundation of China and the Chinese Academy of Sciences,the research team led by Prof.Liu GuangHui(刘光慧)at the CAS National Laboratory of Biomacromolecules,Institute of Biophysics,Chinese Academy of Sciences,generated the world's first genetically enhanced human vascular cells by targeting a single longevity gene,FOXO3.This study was recently published in Cell Stem Cell(2019)as a cover story. 展开更多
关键词 FOXO3-engineered HUMAN esc-derived VASCULAR cells PROMOTE VASCULAR protection REGENERATION
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Ocular stem cells:a narrative review of current clinical trials
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作者 Konstadinos Sotiropulos Dimitrios Kourkoutas +2 位作者 Diamantis Almaliotis Katherine Ploumidou Vasileios Karampatakis 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2022年第9期1529-1537,共9页
·Stem cells are undifferentiated cells showcasing a remarkable capacity of self-replenishing and differentiating into mature cells.Their ability to proliferate connotes that a designated stem cell source is capab... ·Stem cells are undifferentiated cells showcasing a remarkable capacity of self-replenishing and differentiating into mature cells.Their ability to proliferate connotes that a designated stem cell source is capable of generating an unrestricted number of mature cells.The ever-increasing comprehension of position,activity,and function of ocular stem cells has led to rapid progress and incessant improvement of possible procedures and therapies.A narrative review was conducted to summarize the current evidence on clinical trials and respective literature,regarding current evolution in the field of ocular regenerative medicine.We tried to ascertain the safety of experimental and clinical procedures,their effectiveness,and the ethical repercussion of their use. 展开更多
关键词 stem cells cell-based therapies limbal stem cells h esc-derived retinal pigment epithelium human induced pluripotent stem cells olfactory mucosa mesenchymal stem cells
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