AIM:To diagnose the clinical and histologic features that may be associated with or predictive of the need for dilation and dilation related complications;examine the safety of dilation in patients with eosinophilic e...AIM:To diagnose the clinical and histologic features that may be associated with or predictive of the need for dilation and dilation related complications;examine the safety of dilation in patients with eosinophilic esophagitis(EoE).METHODS:The medical records of all patients diagnosed with EoE between January 2002 and July 2010were retrospectively reviewed.Esophageal biopsies were reexamined by an experienced pathologist to confirm the diagnosis(≥15 eos/hpf per current guidelines).Patients were divided into 2 groups:patients who did not receive dilation therapy and those who did.Demographics,clinical history,the use of pharmacologic therapy,endoscopic and pathology findings,and the number of biopsies and dilations carried out,if any,and their locations were recorded for each patient.The dilation group was further examined based on the interval between diagnosis and dilation,and whether or not a complication occurred.RESULTS:Sixty-one patients were identified with EoE and 22(36%)of them underwent esophageal dilations for stricture/narrowing.The peak eos/hpf was significantly higher in patients who received a dilation(P=0.04).Four(18%of pts.)minor complications occurred:deep mucosal tear 1,and small mucosal tears3.There were no cases of esophageal perforations.Higher peak eos/hpf counts were not associated with increased risk of complications.CONCLUSION:Esophageal dilation appears to be a safe procedure in EoE patients,carrying a low complication rate.No correlation was found between the peak of eosinophil count and complication rate.Complications can occur independently of the histologic features.The long-term outcome of EoE treatment,with or without dilation,needs to be determined.展开更多
对不完全规定函数的无关项进行合理赋值,有助于降低其积之异或和(Exclusive-or Sum of Products,ESOP)表示的复杂度.提出一种边实施无关项赋值边进行ESOP化简的不完全规定函数的启发式ESOP最小化算法.该算法采用立方体集合表示函数,首...对不完全规定函数的无关项进行合理赋值,有助于降低其积之异或和(Exclusive-or Sum of Products,ESOP)表示的复杂度.提出一种边实施无关项赋值边进行ESOP化简的不完全规定函数的启发式ESOP最小化算法.该算法采用立方体集合表示函数,首先借助前瞻策略根据立方体间的邻近关系在ReedMuller域实施无关项赋值,然后使用Exorlink运算进行ESOP化简,并对不能降低ESOP复杂度的无关项赋值采用回溯策略进行回溯.使用一组不同规模的MCNC(Microelectronics Center of North China)不完全规定函数对算法进行验证的结果表明,所提算法能够减少ESOP的立方体数以及文字数,并且能够适用于输入数较多的不完全规定函数.展开更多
文摘AIM:To diagnose the clinical and histologic features that may be associated with or predictive of the need for dilation and dilation related complications;examine the safety of dilation in patients with eosinophilic esophagitis(EoE).METHODS:The medical records of all patients diagnosed with EoE between January 2002 and July 2010were retrospectively reviewed.Esophageal biopsies were reexamined by an experienced pathologist to confirm the diagnosis(≥15 eos/hpf per current guidelines).Patients were divided into 2 groups:patients who did not receive dilation therapy and those who did.Demographics,clinical history,the use of pharmacologic therapy,endoscopic and pathology findings,and the number of biopsies and dilations carried out,if any,and their locations were recorded for each patient.The dilation group was further examined based on the interval between diagnosis and dilation,and whether or not a complication occurred.RESULTS:Sixty-one patients were identified with EoE and 22(36%)of them underwent esophageal dilations for stricture/narrowing.The peak eos/hpf was significantly higher in patients who received a dilation(P=0.04).Four(18%of pts.)minor complications occurred:deep mucosal tear 1,and small mucosal tears3.There were no cases of esophageal perforations.Higher peak eos/hpf counts were not associated with increased risk of complications.CONCLUSION:Esophageal dilation appears to be a safe procedure in EoE patients,carrying a low complication rate.No correlation was found between the peak of eosinophil count and complication rate.Complications can occur independently of the histologic features.The long-term outcome of EoE treatment,with or without dilation,needs to be determined.
文摘对不完全规定函数的无关项进行合理赋值,有助于降低其积之异或和(Exclusive-or Sum of Products,ESOP)表示的复杂度.提出一种边实施无关项赋值边进行ESOP化简的不完全规定函数的启发式ESOP最小化算法.该算法采用立方体集合表示函数,首先借助前瞻策略根据立方体间的邻近关系在ReedMuller域实施无关项赋值,然后使用Exorlink运算进行ESOP化简,并对不能降低ESOP复杂度的无关项赋值采用回溯策略进行回溯.使用一组不同规模的MCNC(Microelectronics Center of North China)不完全规定函数对算法进行验证的结果表明,所提算法能够减少ESOP的立方体数以及文字数,并且能够适用于输入数较多的不完全规定函数.
