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Excess Molar Volume, Viscosity and Heat Capacity for the Mixture of 1,2-Propanediol-Water at Different Temperatures 被引量:5
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作者 杨长生 马沛生 +1 位作者 唐多强 靳凤民 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2003年第2期175-180,共6页
Experimental densities, viscosities and heat capacities at different temperatures were presented over the entire mole fraction range for the binary mixture of 1,2-propanediol and water. Density values were used in the... Experimental densities, viscosities and heat capacities at different temperatures were presented over the entire mole fraction range for the binary mixture of 1,2-propanediol and water. Density values were used in the determination of excess molar volumes, VE. At the same time, the excess viscosity was investigated. The values of VE and E were fitted to the Redlich-Kister equation. Good agreement was observed. The excess volumes are negative over the entire range of composition. They show an U-shaped-concentration dependence and decrease in absolute values with increase of temperature. Values of E are negative over the entire range of the composition, and has a trend very similar to that of VE . The analysis shows that at any temperature the specific heat of mixture is a linear function of the composition as x1 > 20%. All the extended lines intersect at one point. An empirical equation is obtained to calculate the specific heat to mixture at any composition and temperature in the experimental range. 展开更多
关键词 VISCOSITY heat capacity DENSITY excess molar volume molecular interaction
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Occurrences of Excess ^(40)Ar in Hydrothermal Tourmaline: Interpretations from ^(40)Ar-^(39)Ar Dating Results by Stepwise Heating 被引量:1
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作者 QIU Huaning PU Zhiping DAI Tongmo 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2007年第3期510-516,共7页
The occurrences of excess ^40Ar within a hydrothermal tourmaline is discussed in term of the analysis data of syngenetic muscovite and tourmaline from the Lushui hydrothermal tin-tungsten deposit in western Yunnan, Ch... The occurrences of excess ^40Ar within a hydrothermal tourmaline is discussed in term of the analysis data of syngenetic muscovite and tourmaline from the Lushui hydrothermal tin-tungsten deposit in western Yunnan, China, using the ^40Ar-^39Ar stepwise heating technique. About 80% excess ^40 Ar was released in the last step when the tourmaline was fused, corresponding to a release of only -3% ^39 Ar (K), which indicates that most excess ^40 Ar was held in the mineral lattice rather than in the channels parallel to the Z-axis. This suggests that the excess ^40 Ar was incorporated during crystallization and not diffused into the tourmaline during the post-crystallization history. 展开更多
关键词 excess ^40 Ar tourmaline ^40 Ar-^39 Ar stepwise heating hydrothermal tin-tungsten deposit Yunnan
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Excess Molar Volume, Viscosity and Heat Capacity for the Binary Mixture of p-Xylene and Acetic Acid at Different Temperatures 被引量:1
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作者 杨长生 马沛生 +2 位作者 唐多强 尹秋响 赵长伟 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2002年第5期604-609,共6页
Experimental densities, viscosities and heat capacities atdifferent temperatures were presented over the entire range of molefraction for the binary mixture of p-xylene and acetic acid. Densityvalues were used in the ... Experimental densities, viscosities and heat capacities atdifferent temperatures were presented over the entire range of molefraction for the binary mixture of p-xylene and acetic acid. Densityvalues were used in the determination of excess molar volumes, V^E.At the same time, the excess viscosity and excess molar heatcapacities were calculated. The values of V^E, η~E and c^E_p werefitted to the Redlich-Kister equation. Good agreements were observed.The excess molar volumes are positive with a large maximum valuelocated in the central concentration range. 展开更多
关键词 VISCOSITY heat capacity DENSITY excess molar volume
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Excess Heat Triggered by Different Current in a D/Pd Gas-Loading System 被引量:3
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作者 Xin Lu Bingjun Shen +3 位作者 Lihong Jin Xinle Zhao Hongyu Wang Jian Tian 《Journal of Energy and Power Engineering》 2013年第7期1299-1303,共5页
In order to study the relationship between the triggering current, deuterium pressure and the excess heat, a series of experiments were made in a D/Pd gas-loading system. By comparing the system constants (k = AT//kP... In order to study the relationship between the triggering current, deuterium pressure and the excess heat, a series of experiments were made in a D/Pd gas-loading system. By comparing the system constants (k = AT//kP) in both nitrogen and deuterium atmosphere we found an optimum current (8 A) and a deuterium pressure (9 x 104 Pa) in which the system could release a maximum excess power (more than 80 W). The reproducibility was 16/16 and the excess energy released in the longest experiment was about 300 MJ within 40 days, which was corresponding to 104 eV for each palladium atom. Analysis of the palladium surface with a SEM (scanning electron microscopy) and an EDS (energy dispersive spectrometer) revealed that some new surface topographical feature with concentrations of unexpected elements (such as Ag, Sn, Pb and Ca) appeared after the current triggering. The results implied that the excess heat might come from a nuclear transmutation. 展开更多
关键词 Current triggering deuterium pressure D/Pd gas-loading system excess heat.
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Excess Heat Power Registration in High Voltage Electrolysis Cell Experiments
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作者 Alexander Karabut 《Journal of Environmental Science and Engineering(A)》 2013年第11期697-711,共15页
Experimental research of the heat and high-energy processes occurring in the cathode solid medium in the high voltage electric discharge system (electrolysis cell and glow discharge device) is presented. The experim... Experimental research of the heat and high-energy processes occurring in the cathode solid medium in the high voltage electric discharge system (electrolysis cell and glow discharge device) is presented. The experiments were carried out: Electrolysis in heavy water with a Pd cathode, electrolysis in light water with Ni and Pd cathodes, the glow discharge in deuterium with a Pd cathode. Excess heat was observed in experiments with high-voltage electrolysis (1,000 V or more). The experiments showed that the maximum excess heat power values of 5-8 W for glow discharge and 180-280 W for high-voltage electrolysis and heat efficiency up to 170% for glow discharge, and 800% for high-voltage electrolysis. The production of impurity nuclide yield showing a shift of up to a few per cent from natural isotopic abundances was detected by spark mass spectrometry and by secondary ionic mass spectrometry. The authors propose based on these experimental results a phenomenological model for low energy nuclear reaction. 展开更多
关键词 Electric discharge excess heat power heat efficiency impurity nuclides.
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Experimental Results on Excess Heat Power, Impurity Nuclides and X-Ray Production in Experiments with a High-Voltage Electric Discharge System
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作者 Alexander Karabut 《Journal of Physical Science and Application》 2014年第2期71-83,共13页
It reviewed results on low-energy nuclear reaction (LENR) processes in a high-voltage (1,000-4,000 V) electric discharge system. The experimental results are divided into three sets: excess heat measurements; yie... It reviewed results on low-energy nuclear reaction (LENR) processes in a high-voltage (1,000-4,000 V) electric discharge system. The experimental results are divided into three sets: excess heat measurements; yield of impurity nuclides (nuclear ash); X-ray measurements. Up to 8 W of excess power was observed, with a power gain of up to 170% was seen in glow discharge experiments. Up to 300 W of excess power, with a power gain up to 340% was observed in experiments using a high-voltage electrolysis cell. The impurity nuclide yield showing a shift of up to a few per cent from natural isotopic abundances was detected by spark mass spectrometry, by secondary ionic mass spectrometry, and by secondary neutral mass spectrometry. X-ray emission in the range of 0.6-6.0 keV, has been observed. Based on these experimental results we propose a phenomenological model for LENR based on the interaction of an electric discharge with condensed matter (of the cathode). 展开更多
关键词 Electric discharge excess heat impurity nuclides X-ray emission
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The crystal change and "excess heat" produced by long time electrolysis of heavy water with titanium cathode
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作者 SUN Yue, ZHANG Qing-fu, GOU Qing-quan (Institute of Atomic and Molecular Physics, Sichuan University, Chengdu 610065, China) 《原子与分子物理学报》 CAS CSCD 北大核心 2003年第1期69-74,共6页
According to the theory given in the paper , the long time electrolysis experiment with titanium cathode in heavy water (D 2O) were done for many times by using the open-loop multi-parameters electrolysis calorimetry ... According to the theory given in the paper , the long time electrolysis experiment with titanium cathode in heavy water (D 2O) were done for many times by using the open-loop multi-parameters electrolysis calorimetry system, which is established by us. The specialty is that the cathode is titanium rod and the anode is platinum wire. The early experiment result is still repeated in our recent experiment. The obvious "excess heat" phenomenon can take place only when the electrolysis last more than ten days and amount of "excess heat" increased with the electrolysis time. The "excess heat" can also be obtained from the "boiling to dry" experiment. In the recent experiment, we obtain the results that the amount of "excess heat" is about 3.6 times the input energy, the "excess heat" power is 76.5 W, and the "excess heat" power density is 121.7 W/cm 3. After the electrolysis, the crystal structure of the Ti cathode was measured with x-ray diffraction apparatus. We found that the crystal structure of Ti cathode was changed to face-centered cubic structure of TiD 2 from its hexagonal structure. This result is in agreement with the Gou’s theory mentioned in reference . 展开更多
关键词 重水 电解实验 热力学 物态变化 晶体结构 热量测定 原子核物理 聚变
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Effect of Metabolic Excesses from Dietary Proteins on Blood Profile of Heat-stressed Broilers
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作者 Ibukun Olukorede Popoola Oluwabukola Rashidat Popoola +4 位作者 Ibukun Oluwatobi Busari Ibikunle Funso Olaleru Damilola Deborah Popoola Omobolanle Ayobami David Oluwaseyi Olamide Olajide 《Journal of Zoological Research》 2021年第4期32-40,共9页
Although,dietary proteins play a crucial role in poultry profit maximization,through the sustenance of birds`welfare,growth and development,yet metabolic excesses from crude protein(CP)degradation is detrimental to br... Although,dietary proteins play a crucial role in poultry profit maximization,through the sustenance of birds`welfare,growth and development,yet metabolic excesses from crude protein(CP)degradation is detrimental to broiler chickens(BC)affected by heat stress.This study evaluated the effect of dietary protein levels on blood profile of heat-stressed BC at starter phase(SP)and finisher phase(FP).Arbor Acre BC(n=288)were randomly allotted to four dietary treatments(T1-23%CP;T2-21%CP;T3-19%CP;and T4-17%CP)with six replicate groups in a completely randomized design.Data were subjected to descriptive analysis,analysis of variance(p=0.05)and correlation statistics.Protein intake(PI)was not significantly affected by varying CP in diets at SP,but not at FP,where PI significantly increased with increasing dietary CP.PER had a negative correlation with PCV(r=-0.89,p<0.01),Hb(r=-0.88,p<0.01),RBC(r=-0.93,p<0.01)and PI(r=-0.78,p<0.01).Metabolic excesses including heat dissipation from dietary proteins influenced PCV,Hb,platelets and glucose of heat-stressed broilers. 展开更多
关键词 Crude protein BROILERS Metabolic excesses heat stress HAEMATOLOGY Protein efficiency
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Excess Heat Power Registration in Experiments with High Voltage Electric Discharge Systems
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作者 Alexander Karabut 《Journal of Energy and Power Engineering》 2013年第9期1735-1744,共10页
The author review results on LENR (low-energy nuclear reaction) processes in the cathodes of a high current glow discharge and a HVEC (high-voltage electrolysis cell). The cathodes used in the experiments were mad... The author review results on LENR (low-energy nuclear reaction) processes in the cathodes of a high current glow discharge and a HVEC (high-voltage electrolysis cell). The cathodes used in the experiments were made of Ni foil, Pd foil, Pd coated Re and solid-state nanostructured Pd. Up to 300 W of excess heat power, with a power gain up to 340%, was observed in experiments using a high-voltage electrolysis cell. Based on these experimental results, we propose a phenomenological model for LENR. 展开更多
关键词 High-voltage discharge excess heat impurity nuclides X-ray emission.
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“瘦人多火症”的因机证治探析
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作者 叶放 孙萌 +3 位作者 周崇怡 万洁 豆晓云 陈潇颖 《南京中医药大学学报》 CAS CSCD 北大核心 2024年第9期880-884,共5页
提出消瘦是临床常见的体质状态,常常会伴随“瘦人多火症”相关证候表现。阴气不足是形体消瘦的主要生理、病理基础,燥火偏旺是形体消瘦的继发表现,病位涉及五脏,核心在脾。治疗原则以滋养阴气为主,宣发郁热为辅。具体包括治本与治标两... 提出消瘦是临床常见的体质状态,常常会伴随“瘦人多火症”相关证候表现。阴气不足是形体消瘦的主要生理、病理基础,燥火偏旺是形体消瘦的继发表现,病位涉及五脏,核心在脾。治疗原则以滋养阴气为主,宣发郁热为辅。具体包括治本与治标两个方面,治本当滋养阴气以改善“消瘦”体质,治标在发散郁热以消除“多火”状态,二者孰轻孰重应依据火旺轻重缓急而定。临床根据病情之标本缓急、消瘦而能食不能食、火热之虚实微盛、病机兼夹以及季节等因素进行药味加减。 展开更多
关键词 千金润脾膏 瘦人多火 阴虚燥热 证治探析 病机 体质
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肺肠同治理论下宣白承气汤结合肠内营养支持在慢性阻塞性肺疾病急性加重期治疗中的应用价值
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作者 朱国清 周妍 +3 位作者 李仙珍 唐丽丽 陈贺 刘志亮 《广州中医药大学学报》 CAS 2024年第9期2312-2318,共7页
【目的】探析肺肠同治理论指导下宣白承气汤结合肠内营养支持在慢性阻塞性肺疾病急性加重(AECOPD)治疗中的应用价值。【方法】将92例AECOPD肺热腑实型患者随机分为观察组和对照组,每组各46例。2组患者均给予常规对症治疗,在此基础上,对... 【目的】探析肺肠同治理论指导下宣白承气汤结合肠内营养支持在慢性阻塞性肺疾病急性加重(AECOPD)治疗中的应用价值。【方法】将92例AECOPD肺热腑实型患者随机分为观察组和对照组,每组各46例。2组患者均给予常规对症治疗,在此基础上,对照组给予肠内营养支持干预,观察组给予宣白承气汤结合肠内营养支持干预,疗程为2周。观察2组患者治疗前后血清白蛋白(albumin,ALB)、前白蛋白(prealbumin,PA)、转铁蛋白(transferrin,TF)等营养指标及肠道菌群分布的变化情况,并比较2组患者的临床疗效及不良反应发生率。【结果】(1)疗效方面,治疗2周后,观察组的总有效率为97.83%(45/46),对照组为82.61%(38/46),组间比较(χ^(2)检验),观察组的疗效明显优于对照组,差异有统计学意义(P<0.05)。(2)营养指标方面,治疗后,2组患者的血清ALB、PA、TF水平均较治疗前明显升高(P<0.05),且观察组对血清ALB、PA、TF水平的升高幅度均明显优于对照组,差异均有统计学意义(P<0.05或P<0.01)。(3)肠道菌群分布方面,治疗后,2组患者的乳杆菌、双歧杆菌菌种数量均较治疗前明显升高(P<0.05),肠球菌菌种数量均较治疗前明显降低(P<0.05),且观察组对肠道乳杆菌、双歧杆菌菌种数量的升高幅度及对肠球菌菌种数量的降低幅度均明显优于对照组,差异均有统计学意义(P<0.05或P<0.01)。(4)不良反应方面,观察组的不良反应发生率为4.35%(2/46),明显低于对照组的19.57%(9/46),组间比较,差异有统计学意义(P<0.05)。【结论】肺肠同治理论指导下宣白承气汤结合肠内营养支持应用于AECOPD肺热腑实型患者临床效果显著,可有效改善患者营养状态及肠道菌群失衡,降低不良反应发生风险。 展开更多
关键词 慢性阻塞性肺疾病急性加重期(AECOPD) 肺热腑实型 宣白承气汤 肺肠同治 肠内营养支持 肠道菌群
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穴位注射结合四妙勇安汤辅助治疗糖尿病足溃疡临床效果观察 被引量:1
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作者 李晨阳 赵钢 +1 位作者 李欣然 于文慧 《中国中西医结合外科杂志》 CAS 2024年第1期18-23,共6页
目的:探讨穴位注射维生素B1结合四妙勇安汤辅助治疗糖尿病足溃疡(DFU)的临床疗效。方法:选取2021年10月-2023年2月我院收治的湿热毒盛型DFU患者96例,随机分为观察组与对照组各48例,对照组给予西医常规治疗,观察组在对照组基础上给予穴... 目的:探讨穴位注射维生素B1结合四妙勇安汤辅助治疗糖尿病足溃疡(DFU)的临床疗效。方法:选取2021年10月-2023年2月我院收治的湿热毒盛型DFU患者96例,随机分为观察组与对照组各48例,对照组给予西医常规治疗,观察组在对照组基础上给予穴位注射结合四妙勇安汤治疗。观察两组患者治疗前后的临床疗效、中医证候评分、踝肱指数及创面情况(创面面积、创面深度),血清炎症指标(超敏C反应蛋白、白细胞介素-1、肿瘤坏死因子-α)、超声检查指标(足背动脉的血流速度、血管内径、阻力指数),血管内皮功能(血管内皮生长因子及血清碱性成纤维细胞生长因子)及复发率。结果:治疗后观察组总有效率为91.67%,显著高于对照组的77.08%(P <0.05);治疗后两组中医证候评分、血清炎症指标、创面面积、创面深度均较治疗前降低,且观察组低于对照组(P <0.05);两组治疗后血清血管内皮生长因子、血清碱性成纤维细胞生长因子水平、踝肱指数及各超声检查指标均较治疗前升高,且观察组高于对照组(P<0.05);观察组复发率10.42%低于对照组的27.08%(P<0.05)。结论:穴位注射维生素B1结合四妙勇安汤辅助治疗湿热毒盛型DFU患者临床疗效显著。 展开更多
关键词 穴位注射 四妙勇安汤 湿热毒盛型 糖尿病足溃疡 创面情况 血管内皮功能
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宣白承气汤对痰热腑实型哮喘大鼠肺组织病理损伤及Th1/Th2失衡影响 被引量:1
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作者 王禹清 张露 +3 位作者 郭松伟 李晨 陆柯 张庆祥 《辽宁中医药大学学报》 CAS 2024年第2期26-30,共5页
目的观察宣白承气汤对痰热腑实型哮喘大鼠肺组织病理损伤情况及血清中Th1/Th2失衡的影响。方法将50只Wistar雄性大鼠随机分为空白组、模型组、定喘汤组、宣白承气汤组、地塞米松组,每组10只。利用卵清蛋白(OVA)诱导哮喘模型,并施加痰热... 目的观察宣白承气汤对痰热腑实型哮喘大鼠肺组织病理损伤情况及血清中Th1/Th2失衡的影响。方法将50只Wistar雄性大鼠随机分为空白组、模型组、定喘汤组、宣白承气汤组、地塞米松组,每组10只。利用卵清蛋白(OVA)诱导哮喘模型,并施加痰热腑实因素,造模成功后,实验组按体质量1.5 mL/100 g分别给予定喘汤、宣白承气汤和地塞米松溶液,空白对照组与模型组按等比例给予0.9%氯化钠溶液,1次/d,连续用药14 d后,观察各组大鼠一般情况;记录各组大鼠体质量、肛温及代谢情况;HE染色观察大鼠肺组织病理改变情况,酶联免疫吸附测定法(ELISA)比较大鼠血清中Th1细胞因子白细胞介素(IL)-4和Th2细胞因子干扰素-γ(IFN-γ)的含量。结果空白组大鼠一般状态良好,毛发柔顺光泽,呼吸节律均匀平稳,四肢温和,体质量呈稳定增长趋势,肛温无异常增高,日均进食进水量平稳,大便量多质润;模型组大鼠精神状态差,毛发粗糙凌乱,呼吸节奏加快,可闻及哮鸣音,且抓挠口鼻频率增高,周围可见淡黄色黏性分泌物,体质量增长趋势较空白组减缓,且整体体质量偏低,肛温较空白组显著升高(P<0.01),日均进食进水量显著下降(P<0.01),24 h排便量明显减少(P<0.01)且质地坚硬;定喘汤组大鼠精神状态良好,毛发较模型组平整,口鼻处少见黏性分泌物,偶见喘息气急、搔鼻、打喷嚏,呼吸节律随给药时间延长趋于平稳,体质量增长与模型组相近,给药后肛温明显降低(P<0.05),日均进水量较模型组稍有升高(P>0.05),进食量稍有增多(P<0.05),24 h排便量增多(P>0.05)且质地变软;宣白承气汤组大鼠服药后整体状态良好,毛发光泽平整,口鼻黏性分泌物减少,呼吸喘息急促等症状相应改善,大鼠哮鸣音减少,抓挠口鼻频率低,体质量增长趋势较模型组更缓,且整体体质量小于模型组(P<0.01),给药后大鼠肛温显著降低(P<0.01),日均进食量进水量均增多(P<0.01),大便质软量多(P<0.01);地塞米松组大鼠用药1周期间各项状态较为稳定,继续用药后虽喘息气促明显改善,口鼻分泌物减少,但大鼠性情逐渐暴躁,肌肉僵直,皮肤松垮,毛发杂乱枯燥,体质量较模型组显著减少(P<0.01),肛温明显降低(P<0.01),日均进水量稍有增多(P>0.05),给药1周后日均进食量显著减少(P<0.01),继续给药后日均进食量稍有减少(P>0.05),24 h排便量增多(P>0.05),且质稀软。组织病理切片显示空白组大鼠未见炎性病理改变,模型组可见明显炎性浸润,治疗后定喘汤组、宣白承气汤组、地塞米松组大鼠肺组织病理情况均有所缓解;ELISA结果显示模型组大鼠血清Th1细胞因子IFN-γ水平较空白组显著下降(P<0.01),Th2细胞因子IL-4水平较空白组显著升高(P<0.01),经宣白承气汤给药后大鼠IFN-γ水平显著升高(P<0.01),IL-4水平显著降低(P<0.01)。结论宣白承气汤可以通过泄热通腑的方法治疗痰热腑实型哮喘,改善哮喘症状,缓解大鼠肺组织病理损伤,改变血清中IL-4和IFN-γ的含量,从而调节Th1/Th2失衡。 展开更多
关键词 宣白承气汤 痰热腑实 哮喘 病理改变 TH1/TH2
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缺血性脑卒中痰热腑实证大鼠模型的建立与评价
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作者 平兴枫 吕军影 +2 位作者 李凯 黄宗轩 尹建新 《中国组织工程研究》 CAS 北大核心 2025年第11期2301-2309,共9页
背景:中医药在治疗缺血性脑卒中痰热腑实证中具有丰富的经验和独特的优势,为深入挖掘中医药对该病的治疗靶点和治疗机制,建立稳定、可靠的缺血性脑卒中痰热腑实证病证结合动物模型是关键。目的:探讨缺血性脑卒中痰热腑实证大鼠模型的建... 背景:中医药在治疗缺血性脑卒中痰热腑实证中具有丰富的经验和独特的优势,为深入挖掘中医药对该病的治疗靶点和治疗机制,建立稳定、可靠的缺血性脑卒中痰热腑实证病证结合动物模型是关键。目的:探讨缺血性脑卒中痰热腑实证大鼠模型的建立方法及评价体系。方法:采用随机数字表法将60只SD大鼠随机分为4组:空白对照组(n=12)、缺血性脑卒中组(n=18)给予普通饲料喂养25 d,病证结合组(n=18)、痰热腑实证组(n=12)给予高脂饲料喂养25 d;第26天,空白对照组、缺血性脑卒中组灌胃给予生理盐水,病证结合组、痰热腑实证组灌胃给予自体粪便混悬液,连续灌胃3 d(灌胃期间继续给予高脂饲料);灌胃结束后,缺血性脑卒中组、病证结合组采用线栓法建立缺血性脑卒中模型,记录各组大鼠饮食量、饮水量、体质量、体温、粪便性状、鼻分泌物、喉中痰鸣、舌象等表征变化。造模结束后24 h,进行神经功能缺损评分、舌象表征、血脂水平检测、脑组织及颈动脉形态学观察以及血清胃动素和生长抑素水平检测。结果与结论:(1)与空白对照组比较,病证结合组大鼠呼吸急促、精神萎靡、烦躁、行动迟缓,鼻周可见大量分泌物、可闻及厚重的喉中痰鸣,饮食量、饮水量下降,体质量、体温及舌下脉络评分升高,粪便粒数、Bristol评分及粪便含水率降低;血清总胆固醇、三酰甘油、低密度脂蛋白胆固醇及生长抑素水平升高,胃动素水平降低,神经功能缺损评分升高,颈动脉发生显著病理改变,脑组织显示明显缺血形态学改变。缺血性脑卒中组仅能造成缺血性脑组织病理改变,不能复制出痰热腑实证的证候特征。痰热腑实证组能复制出典型的中医证候特征,但不能构建出缺血性脑卒中的脑组织病理改变。(2)结果表明,高脂诱导结合线栓法及自体粪便灌胃的多因素复合造模方法,可建立缺血性脑卒中痰热腑实证病证结合动物模型。 展开更多
关键词 缺血性脑卒中 痰热腑实证 病证结合 动物模型 症候因素
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通腑逐瘀方联合常规西药治疗腑实热结证急性胰腺炎临床研究 被引量:1
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作者 李芝萍 汪娅君 +2 位作者 张菊萍 徐涛 李俊华 《新中医》 CAS 2024年第10期81-85,共5页
目的:观察通腑逐瘀方辅助西药治疗腑实热结证急性胰腺炎的临床疗效。方法:选择98例急性胰腺炎患者,按随机数字表法分为联合组和对照组各49例。对照组给予常规西医治疗,联合组在对照组基础上联合通腑逐瘀方治疗。治疗7 d后,比较2组临床... 目的:观察通腑逐瘀方辅助西药治疗腑实热结证急性胰腺炎的临床疗效。方法:选择98例急性胰腺炎患者,按随机数字表法分为联合组和对照组各49例。对照组给予常规西医治疗,联合组在对照组基础上联合通腑逐瘀方治疗。治疗7 d后,比较2组临床疗效、中医证候评分、临床症状恢复时间、炎症因子和肠黏膜屏障功能指标变化。结果:治疗后,联合组总有效率为93.88%,对照组为79.59%,2组比较,差异有统计学意义(P<0.05)。治疗后,联合组腹胀缓解时间、腹痛减轻时间、肠鸣音恢复时间、首次排气时间均短于对照组,差异有统计学意义(P<0.05)。治疗后,2组主、次症中医证候评分及总分均较治疗前降低(P<0.05),且联合组主、次症评分及总分均低于对照组(P<0.05)。治疗后,2组白细胞计数(WBC)、C-反应蛋白(CRP)、白细胞介素-6(IL-6)水平较治疗前降低(P<0.05),且联合组3项指标水平均低于对照组(P<0.05)。治疗后,2组二胺氧化酶(DAO)、D-乳酸、内毒素水平均较治疗前降低(P<0.05),且联合组3项指标水平均低于对照组(P<0.05)。结论:通腑逐瘀方联合常规西药治疗急性胰腺炎,可以进一步提高疗效,改善中医证候,加快临床症状康复,减轻炎症反应并改善肠黏膜屏障功能。 展开更多
关键词 急性胰腺炎 腑实热结证 通腑逐瘀方 炎症因子 肠黏膜屏障功能
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白虎二至汤治疗热盛阴虚型糖尿病肾病Ⅲ期临床观察 被引量:1
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作者 王国玉 姜敏 +3 位作者 刘馨心 马思懿 黄博臻 宋姗姗 《光明中医》 2024年第5期920-923,共4页
目的 观察白虎二至汤对热盛阴虚型糖尿病肾病(DKD)Ⅲ期患者的临床疗效。方法 将66例DKD患者随机分为对照组和治疗组,各33例。对照组采用缬沙坦胶囊治疗,治疗组在对照组治疗上加用白虎二至汤,观察2组患者空腹血糖(FBG)、餐后2 h血糖(2 h ... 目的 观察白虎二至汤对热盛阴虚型糖尿病肾病(DKD)Ⅲ期患者的临床疗效。方法 将66例DKD患者随机分为对照组和治疗组,各33例。对照组采用缬沙坦胶囊治疗,治疗组在对照组治疗上加用白虎二至汤,观察2组患者空腹血糖(FBG)、餐后2 h血糖(2 h PG)、糖化血红蛋白(HbA1c)、尿蛋白/肌酐比(UACR)、尿素氮(BUN)、血肌酐(Scr)以及中医证候积分水平。结果 治疗组有效率显著优于对照组(P<0.05)。治疗后2组患者的2 h PG、HbA1c、UACR、BUN、Scr及中医证候积分水平均低于治疗前(P<0.05),且治疗组均低于对照组(P<0.05)。结论 白虎二至汤可显著改善早期糖尿病肾病患者的临床症状及中医证候,控制血糖水平,改善肾功能,延缓患者疾病进展,提高患者生活质量。 展开更多
关键词 消渴 糖尿病肾病 热盛阴虚证 白虎二至汤 中医药疗法
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《金匮要略》柔痉的再辨析
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作者 王爽 李小会 +2 位作者 辜桂兰 陈丽名 屈杰 《四川中医》 2024年第6期26-28,共3页
由于历史背景的原因,仲景论治柔痉多从外感风寒入手,认为柔痉多由外感风寒过汗误治化热而来,瓜蒌桂枝汤为治疗柔痉一病的专方。而后世医家受温病学启发认为柔痉亦可由津液亏虚外感风热而发,瓜蒌桂枝汤非治疗柔痉之良方。通过分析原文与... 由于历史背景的原因,仲景论治柔痉多从外感风寒入手,认为柔痉多由外感风寒过汗误治化热而来,瓜蒌桂枝汤为治疗柔痉一病的专方。而后世医家受温病学启发认为柔痉亦可由津液亏虚外感风热而发,瓜蒌桂枝汤非治疗柔痉之良方。通过分析原文与各家注释,旁参《伤寒论》中相关条文对《金匮要略》中柔痉的相关内容再次进行辨析,认为《金匮要略》中所论述的柔痉既可起于风寒误治,亦可源于津液亏虚直接外感风热,但其基本病机均为热盛津伤。而瓜蒌桂枝汤为治疗柔痉的主方,应当根据临床实际辨证用之。 展开更多
关键词 柔痉 热盛津伤 瓜蒌桂枝汤 《金匮要略》
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宣白承气汤对痰热腑实型哮喘大鼠肺组织病理损伤及Th17/Treg失衡的影响
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作者 王禹清 张露 +3 位作者 郭松伟 李晨 陆柯 张庆祥 《中医药信息》 2024年第2期33-38,共6页
目的:观察宣白承气汤对痰热腑实型哮喘大鼠肺组织病理损伤情况及肺泡灌洗液(BALF)中Th17/Treg失衡的影响。方法:将50只Wistar雄性大鼠随机分为空白对照组(A组)、模型组(B组)、定喘汤组(C组)、宣白承气汤组(D组)和地塞米松组(E组),每组1... 目的:观察宣白承气汤对痰热腑实型哮喘大鼠肺组织病理损伤情况及肺泡灌洗液(BALF)中Th17/Treg失衡的影响。方法:将50只Wistar雄性大鼠随机分为空白对照组(A组)、模型组(B组)、定喘汤组(C组)、宣白承气汤组(D组)和地塞米松组(E组),每组10只。利用OVA诱导哮喘模型,并施加痰热腑实因素,造模成功后,C组、D组和E组分别按1.5mL/100g给予定喘汤(0.067g/mL)、宣白承气汤(0.036g/mL)和地塞米松溶液[0.05 mg/(100 g·d)],A组和B组按等比例给予生理盐水,1次/d,连续用药14 d后,观察各组大鼠一般情况;HE染色观察大鼠肺组织病理改变情况,酶联免疫吸附法(ELISA)比较大鼠肺泡灌洗液中IL-6、转化生长因子-β(TGF-β)、IL-17、IL-10的含量。结果:病理切片结果显示,A组未见炎性细胞浸润,肺泡扩张良好、支气管黏膜正常;B组可见大量嗜酸性粒细胞及淋巴细胞浸润等支气管哮喘病理表现;C组、D组和E组细胞炎性浸润均减少,病理情况均有所改善。ELISA结果显示,与A组比较,B组肺泡灌洗液中IL-6和IL-17水平显著上升(均P<0.01);与B组比较,C组、D组、E组IL-6和IL-17水平均下降(均P<0.01);与A组比较,B组肺泡灌洗液中TGF-β和IL-10水平均下降(均P<0.01);与B组比较,D组两种细胞因子水平均显著上升(均P<0.01);C组TGF-β水平上升(P<0.05),IL-10水平明显上升(P<0.01);E组IL-10水平明显上升(P<0.01),但TGF-β上升不明显(P>0.05)。结论:宣白承气汤可以通过泄热通腑的方法治疗痰热腑实型哮喘,改善哮喘症状,缓解大鼠肺组织病理损伤,改变肺泡灌洗液中IL-6、TGF-β、IL-17、IL-10的含量,从而调节Th17/Treg失衡。 展开更多
关键词 宣白承气汤 痰热腑实 哮喘 病理改变 TH17/TREG
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出生日期五运六气对后天罹患乳房肿瘤良恶性倾向的趋势性分析
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作者 钟莎 叶甜婧 +2 位作者 林颖曈 李军 谢丹 《广州中医药大学学报》 CAS 2024年第6期1393-1400,共8页
【目的】探讨女性乳房良恶性肿瘤患者出生日期的五运六气特点以及异同性,并围绕罹患乳房肿瘤的良恶性倾向展开趋势性分析。【方法】从广州中医药大学第一附属医院的电子病例系统中采集723例乳房恶性肿瘤(乳腺癌)患者和1595例乳房良性肿... 【目的】探讨女性乳房良恶性肿瘤患者出生日期的五运六气特点以及异同性,并围绕罹患乳房肿瘤的良恶性倾向展开趋势性分析。【方法】从广州中医药大学第一附属医院的电子病例系统中采集723例乳房恶性肿瘤(乳腺癌)患者和1595例乳房良性肿瘤患者的出生日期信息,运用SPSS 25.0统计学软件对2组患者的运气学信息进行统计分析。【结果】(1)岁运方面,木运太过、火运太过、土运不及之年出生的患者倾向性于罹患乳腺癌,而金运不及、木运不及、水运太过之年出生的患者倾向于患乳房良性肿瘤。(2)主气方面,出生于少阴君火的患者更倾向于罹患乳腺癌,而出生于厥阴风木、太阴湿土的患者更倾向于患乳房良性肿瘤。(3)客气方面,出生于厥阴风木、阳明燥金的患者更倾向于罹患乳腺癌,而出生于少阳相火、太阳寒水的患者更倾向于患乳房良性肿瘤。(4)出生季节方面,出生于春季的患者更倾向于罹患乳腺癌。(5)运气相合方面,出生于小逆/不和/天刑的患者患乳腺癌的倾向性更大,而出生于岁会/同岁会的患者更倾向于患乳房良性肿瘤。(6)司天-在泉方面,出生之年的司天-在泉组合情况对乳腺癌和乳房良性肿瘤的影响并无明显的统计学差异。【结论】(1)乳房良恶性肿瘤之间的出生日期的运气信息有一定的差异性和倾向性。(2)从运气学角度分析,乳腺癌患者出生日期的相关运气气候以风、热为特点,病变部位主要涉及肝、脾、心、肾,且相较于乳房良性肿瘤患者,其体质禀赋更偏向于实性、热性。 展开更多
关键词 乳腺肿瘤 乳房良恶性肿瘤 出生日期 五运六气 趋势性分析 体质禀赋 实性 热性
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高温高压氛围下煤体吸附瓦斯特性研究 被引量:2
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作者 申晓静 岳基伟 +3 位作者 梁跃辉 王辰 徐金林 韩奇峻 《中国安全科学学报》 CAS CSCD 北大核心 2024年第2期176-184,共9页
深部开采面临着高温高压环境,为厘清深部煤体的吸附瓦斯特性,采用等温吸附试验、分子动力学等温吸附模型及理论分析相结合的方法,从宏观角度和微观角度,探究高温高压氛围下煤体吸附瓦斯特性。结果表明:瓦斯压力较低时,不同温度下,绝对... 深部开采面临着高温高压环境,为厘清深部煤体的吸附瓦斯特性,采用等温吸附试验、分子动力学等温吸附模型及理论分析相结合的方法,从宏观角度和微观角度,探究高温高压氛围下煤体吸附瓦斯特性。结果表明:瓦斯压力较低时,不同温度下,绝对吸附量与过剩吸附量的差值差别不大;瓦斯压力较高时,绝对吸附量与过剩吸附量的差值随着温度的升高而增大;瓦斯压力从0 MPa逐渐增加到20 MPa的过程中,煤体吸附瓦斯量分为前期快速增加、中期短暂稳定、后期逐渐减小3个阶段;煤的等量吸附热与吸附量满足指数函数关系;基于等量吸附热推演的温度-压力吸附模型可以预测任意温度和压力条件下的等温吸附瓦斯量,预测值与实测值相对误差小于12%。 展开更多
关键词 高温高压 煤体吸附瓦斯 吸附特性 绝对吸附量 过剩吸附 等量吸附热
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