朗讯公司OPENetSolution的EXS平台及应用

随着全球信息产业的迅猛发展,电信政策的不断放宽,电信产业在业务方面、网络方面、地理区域上,以及从个人用户到基础设施都在经历一场前所未有的变革。全球化和开放趋势正在刺激人们对网络集成、多种独特的增值业务以及多媒体通信的广泛需求。电信运营商、系统集成商和开发商在这些新出现的市场中享有空前的机遇。

An exsitu underground coal gasification experiment with a siderite interlayer:course of the process,production gas,temperatures and energy efficiency

A 72-h ex situ hard coal gasification test in one large block of coal was carried out.The gasifying agent was oxygen with a constant flow rate of 4.5 m^(3)/h.The surroundings of coal were simulated with wet sand with 11%moisture content.A 2-cm interlayer of siderite was placed in the horizontal cut of the coal block.As a result of this process,gas with an average flow rate of 12.46 m^(3)/h was produced.No direct influence of siderite on the gasification process was observed;however,measurements of CO_(2)content in the siderite interlayer before and after the process allow to determine the location of high-temperature zones in the reactor.The greatest influence on the efficiency of the gasification process was exerted by water contained in wet sand.At the high temperature that prevailed in the reactor,this water evaporated and reacted with the incandescent coal,producing hydrogen and carbon monoxide.This reaction contributes to the relatively high calorific value of the resulting process gas,averaging 9.41 MJ/kmol,and to the high energy efficiency of the whole gasification process,which amounts to approximately 70%.

深度学习下吊装作业工人防护装备及吊钩检测方法

为解决危大工程中吊装作业安全管理的问题,基于深度学习构建目标检测算法(You Only Look Once version 5,YOLOv5)网络模型,针对进入吊装作业区域内人员的防护装备进行多目标融合检测,并对吊钩在施工过程中的状态进行检测。在原始的检测网络模型中引入4种注意力机制,并通过5种训练模型的结果对比分析,进而选择卷积块注意力模块(Convolutional Block Attention Module,CBAM)最优模型。优化后的检测模型对安全帽的平均识别精度达86.5%,对反光衣的平均识别精度达83.0%,对吊钩的状态识别精度达92.0%。将训练好的人员检测模型和吊钩检测模型打包成exe执行文件,应用到施工安全管理人员的中控平台,可帮助管理人员更好地判断吊装作业的工作情况,进而及时进行风险管控。

微生物质谱仪对碳青霉烯类耐药肺炎克雷伯菌的检测性能评价

目的探讨评价EXS3000全自动微生物质谱仪(以下简称质谱仪)在快速检测碳青霉烯类耐药肺炎克雷伯菌(CRKP)检测性能。方法随机选取该医院临床微生物室保存的非重复CRKP菌株97株,碳青霉烯类敏感肺炎克雷伯菌(CSKP)99株。所有保存菌株均为临床分离鉴定率在98%以上的CRKP菌株。采用质谱仪检测肺炎克雷伯菌对亚胺培南的水解能力,通过测定特定的基质峰消失情况来判断细菌对亚胺培南是否耐药。对于质谱仪检测亚胺培南敏感的CRKP菌株进行K-B法、E-test法复核,分别用mCIM试验和免疫显色试剂检测细菌产碳青霉烯酶情况。免疫显色阳性结果,采用PCR扩增相应耐药基因;二代测序检测编码碳青霉烯酶耐药基因。通过比较分析质谱仪对CRKP的检测能力。结果质谱仪对97株CRKP检测中,94株为亚胺培南耐药,3株为亚胺培南敏感,符合率为96.91%;对99株CSKP检测亚胺培南均为敏感,符合率为100%。对亚胺培南敏感CRKP菌株进行K-B法、E-test法复核结果为亚胺培南耐药,经mCIM试验检测为非产碳青霉烯酶菌株,免疫显色法检测显示NDM型碳青霉烯酶为弱阳性,PCR法未扩增到NDM型碳青霉烯酶耐药基因,二代测序结果中未检测到编码碳青霉烯酶的基因。结论EXS3000全自动微生物质谱仪可用于产碳青霉烯酶CRKP的快速检测,对于非产碳青霉烯酶的CRKP菌株检测能力不足,具体机制有待进一步研究。

国际实践视角下我国商事仲裁释明规则的构建

由于理论上和实践中对其性质的争论以及仲裁规则中制度的缺失,我国仲裁释明的行使缺乏明确的指引,根本无法发挥其应有的作用。通过对于国际仲裁法律原则以及主流仲裁机构规则的分析可以确定,仲裁庭释明的基础是源自仲裁庭本身的调查权以及裁判者知法原则的适用,因此应更多地解释为仲裁庭权利的范畴。释明的目的和效果与商事仲裁所追求的理念高度契合,因此在仲裁领域应有着更为广泛的适用空间。对于释明可能带来的负面影响,则可以通过仲裁规则中特定程序的使用、当事人异议权的保障以及司法审查标准的明确等方式充分加以消除。

Ex vivo liver resection and auto-transplantation as an alternative for the treatment of liver malignancies: Progress and challenges

Hepatectomy is still the major curative treatment for patients with liver malignancies.However,it is still a big challenge to remove the tumors in the central posterior area,especially if their location involves the retrohepatic inferior vena cava and hepatic veins.Ex vivo liver resection and auto-transplantation(ELRA),a hybrid technique of the traditional liver resection and transplantation,has brought new hope to these patients and therefore becomes a valid alternative to liver transplantation.Due to its technical difficulty,ELRA is still concentrated in a few hepatobiliary centers that have experienced surgeons in both liver resection and liver transplantation.The efficacy and safety of this technique has already been demonstrated in the treatment of benign liver diseases,especially in the advanced alveolar echinococcosis.Recently,the application of ELRA for liver malignances has gained more attention.However,standardization of clinical practice norms and international consensus are still lacking.The prognostic impact in these oncologic patients also needs further evaluation.In this review,we summarized the principles and recent progresses on ELRA.

870 EX型涡流纺纱机优势分析及应用

为了探索新型涡流纺纱设备的优势,从数字技术、机械与电气自动化、自动接头装置、质量检测和分析系统等方面介绍870 EX型涡流纺纱机的技术创新点,从条干、毛羽、重量不匀率水平3方面分析其工艺优势;详述应用870 EX型涡流纺纱机纺R 19.7 tex麻灰纱的原料选用、工艺参数、测试仪器及标准,并与环锭纺和转杯纺进行成纱质量对比。指出:870 EX型涡流纺纱机技术先进,具有高产、高效、高速的工艺优势;纺R 19.7 tex麻灰纱的纱线毛羽少、抗起毛起球性好,满足针织用纱质量要求;纺纱速度达转杯纺的4倍以上,环锭纺的30倍以上,生产效率高且成纱质量稳定。

Coleus forskohlii shows anti-psoriatic activity in imiquimod-induced psoriasis rats

Objective:To evaluate anti-psoriatic activity of Coleus forskohlii in rats with imiquimod-induced psoriasis.Methods:Imiquimod was used to induce psoriasis in rats.Body weight,skin thickness,erythema,scaling,spleen weight,and histological alternations were measured to assess the effect of Coleus forskohlii.Furthermore,an emulgel formulation containing Coleus forskohlii 10%was prepared and characterized along with its ex vivo permeation studies.Results:The emulgel formulation containing Coleus forskohlii 10%had a pH of 5.40±0.36,with optimum spreadability of(31.67±2.08)g/(cm·s)and viscosity of(15966.67±1274.10)cps,and enhanced both the rate and the extent of drug permeation through psoriatic skin.In an ex vivo study,the quantity of drug permeated(19.18%),deposited(52.38%),and drug remaining in the donor compartments(28.31%)was satisfactory.Coleus forskohlii significantly alleviated imiquimod-induced psoriasis by increasing glutathione and superoxide dismutase activity,decreasing malondialdehyde and nitric oxide levels,and alleviating histological alternations in rat skin.Conclusions:Coleus forskohlii can alleviate imiquimod-induced psoriasis,which may be used as a therapeutic candidate for the treatment of psoriasis.

Storm Liquefaction Deposits:A Possibility of Time Reversal in Sedimentary Strata of an Estuarial Coastal Area

In the sedimentary strata dating of estuarial coastal areas,it is often found that there is phenomenon of time-reversal in strata.The seabed sediments could be liquefied under storm waves.A laboratory wave flume experiment demonstrated that storm-induced liquefaction deposits are formed by the oscillations of liquefied sediments.In this paper,the particle size distribution and ^(210)Pb_(ex) specific activity of the sediment samples from the liquefaction disturbed zone and adjacent stable zone of the Yellow River Delta were tested.The stratigraphic divisions based on storm liquefaction deposit sequence can effectively explain the vertical changes in particle size and ^(210)Pb_(ex) specific activity.Due to the differentiation of particles during the storm induced liquefaction,coarse and fine particles regrouped,which could explain the phenomenon of time-reversal in dating data.

Ex vivo liver resection and auto-transplantation and special systemic therapy in perihilar cholangiocarcinoma treatment

This editorial contains comments on the article“Systematic sequential therapy for ex vivo liver resection and autotransplantation:A case report and review of li-terature”in the recent issue of World Journal of Gastrointestinal Surgery.It points out the actuality and importance of the article and focuses primarily on the role and place of ex vivo liver resection and autotransplantation(ELRAT)and systemic therapy,underlying molecular mechanisms for targeted therapy in perihilar cho-langiocarcinoma(pCCA)management.pCCA is a tough malignancy with a high proportion of advanced disease at the time of diagnosis.The only curative option is radical surgery.Surgical excision and reconstruction become extremely com-plicated and not always could be performed even in localized disease.On the other hand,ELRAT takes its place among surgical options for carefully selected pCCA patients.In advanced disease,systemic therapy becomes a viable option to prolong survival.This editorial describes current possibilities in chemotherapy and reveals underlying mechanisms and projections in targeted therapy with ki-nase inhibitors and immunotherapy in both palliative and adjuvant settings.Fi-broblast grow factor and fibroblast grow factor receptor,human epidermal grow-th factor receptor 2,isocitrate dehydrogenase,and protein kinase cAMP activated catalytic subunit alpha(PRKACA)and beta(PRKACB)pathways have been ac-tively investigated in CCA in last years.Several agents were introduced and approved by the Food and Drug Administration.They all demonstrated mean-ingful activity in CCA patients with no global change in outcomes.That is why every successfully treated patient counts,especially those with advanced disease.In conclusion,pCCA is still hard to treat due to late diagnosis and extremely complicated surgical options.ELRAT also brings some hope,but it could be performed in very carefully selected patients.Advanced disease requires systemic anticancer treatment,which is supposed to be individualized according to the genetic and molecular features of cancer cells.Targeted therapy in combination with chemo-immunotherapy could be effective in susceptible patients.

瓦里安Clinac 23EX医用直线加速器故障维修1例

介绍了瓦里安Clinac 23EX医用直线加速器在开机晨检中出现的FLOW联锁故障,分析了故障产生的原因,提出了具体的故障排除思路与维修方法,为同行维修类似故障提供了参考。

瓦里安23EX医用直线加速器多叶准直器故障维修实例研究

随着医疗领域的快速发展,医用直线加速器多叶准直器成为医用加速器治疗直准器的重要配置,为医疗临床放疗提供重要的设备。同时,在医用直线加速器照射旋转期间,可以结合实际情况,利用多叶准直器对射野形状进行调节,并且根据靶区的头型形状,利用计算机对多叶准直器的运行进行严格控制,从而实况多动态放射治疗。但是,多叶准直器在长期运行中,难免会产生一些故障,所以本文立足瓦里安23EX医用直线加速器,对多叶准直器故障进行总结,有针对性进行维修,确保多叶准直器可以正常运行,满足医疗放射治疗需求,也给相关研究工作提供一定参考。

莱阳市九个南瓜品种的果实品质比较

选取9个南瓜[Cucurbita moschata(Duchesne ex Lam.)Duchesne ex Poir.]品种进行果实品质及营养成分含量的比较,筛选出适宜山东省莱阳市种植的优质南瓜品种。结果表明,红板栗南瓜最轻,德丰银栗和红板栗南瓜的果实品质较好;甜蜜蜜红蜜南瓜的维生素C含量最高,红板栗南瓜次之;德丰银栗的可溶性糖含量最高。可见,德丰银栗和红板栗南瓜在物理性状和营养成分上表现的综合品质较优,是莱阳市值得推广和发展的优良品种。

AXDL-杀菌剂在电厂水处理设备的研究与应用

本文详细论述了EX系列AXDL-杀菌剂发生装置在某电厂的应用情况及出现的问题、解决措施等一系列内容,以EX系列综合法AXDL-杀菌剂发生装置为对象,探究了其发生反应的原理、工艺流程及特点。而后,指出EX系列综合法AXDL-杀菌剂发生装置在现场的应用情况,分析了EX系列综合法AXDL-杀菌剂发生装置在实际运行中的优缺点,以明确EX型AXDL-杀菌剂发生装置在某电厂的应用路径。

SIRT1通过CREB/BDNF通路调控吗啡诱导大鼠条件位置偏爱的机制研究

目的研究腹外侧眶皮层(ventrolateral orbital cortex,VLO)内微量注射sirtuin1(SIRT1)抑制剂EX527对吗啡诱导大鼠条件位置偏爱(conditioned place preference,CPP)的影响,并探讨CREB/BDNF通路在其中的作用。方法应用脑立体定位术在大鼠双侧VLO内留置导管,建立吗啡诱导大鼠CPP模型,d 1为适应,d 2~4为前测,d 5~14为条件性训练,隔日交替腹腔注射吗啡(1 mL·kg^(-1),5 mg·kg^(-1))或生理盐水(1 mL·kg^(-1)),提前30 min通过导管向双侧VLO内微量注射EX527(1μL,5 g·L^(-1))或DMSO(1%,1μL),d 15为测试。CPP测试后立即取脑分离VLO组织,Western blot检测VLO内SIRT1、PSD95、c-fos、p-ERK、CREB、BDNF的表达水平。结果吗啡诱导大鼠CPP模型构建成功,吗啡诱导CPP形成组VLO内SIRT1、PSD95、c-fos、p-ERK、CREB蛋白表达明显增高(P<0.05),BDNF蛋白表达明显降低(P<0.05)。VLO内微量注射EX527抑制了吗啡诱导大鼠CPP形成,且明显降低了VLO内SIRT1、PSD95、c-fos、p-ERK、CREB、BDNF蛋白表达(P<0.05)。结论EX527通过抑制吗啡引起的VLO内SIRT1及其下游相关分子表达的增高,并进一步降低BDNF表达,从而有效阻断了大鼠吗啡成瘾的形成。

土壤调理剂对土壤理化性质及韭菜品质的影响

研究了高钾型类沸石分子筛土壤调理剂对韭菜(Allium tuberosum Rottler ex Spr.)种植土壤理化性质、韭菜植株生长和品质指标的影响。结果表明,施用50 kg/667m2土壤调理剂显著增加了韭菜种植土壤中全磷、有效磷、全钾、速效钾、交换性钙、交换性镁含量,增幅为17.54%~273.42%;促进了韭菜植株生长,表现为显著增加植株的茎粗、叶长、最大叶宽和生物量,增幅为9.62%~54.84%;显著提高了韭菜叶片叶绿素、可溶性糖及可溶性蛋白含量,增幅为32.31%~88.41%;显著提高了韭菜植株灰分、全钾、全硫含量,增幅为6.56%~9.60%。通过GC-MS联用对韭菜挥发性成分进行分析,发现土壤调理剂明显提高了二甲基三硫醚含量,二硫醚、二硫烷化合物含量呈降低趋势。施用土壤调理剂可改善土壤理化性质、促进韭菜生长、增加韭菜产量、改善韭菜品质,实现韭菜生产的节本增效。

Systematic sequential therapy for ex vivo liver resection and autotransplantation: A case report and review of literature

BACKGROUND Perihilar cholangiocarcinoma(pCCA)is a highly malignant tumor arising from the biliary tree.Radical surgery is the only treatment offering a chance of long-term survival.However,limited by the tumor’s anatomic location and peri-vascular invasion,most patients lose the chance for curative treatment.Therefore,more methods to increase the resectability of tumors as well as to improve outcomes are needed.CASE SUMMARY A 68-year-old female patient had a hepatic hilar mass without obvious symptoms.Laboratory results showed hepatitis B positivity.Magnetic resonance imaging indicated that the mass(maximum diameter:41 mm)invaded the left and right branches of the main portal vein,as well as the middle,left and right hepatic veins;enlarged lymph nodes were also detected in the hilum.The patient was diagnosed with pCCA,and the clinical stage was determined to be T4N1M0(stage IIIC).Considering the tumor’s anatomic location and vascular invasion,systematic conversion therapy followed by ex vivo liver resection and autotrans-plantation(ELRA)was determined as personalized treatment for this patient.Our original systemic sequential therapeutic strategy(lenvatinib and tislelizumab in combination with gemcitabine and cisplatin)was successfully adopted as conversion therapy because she achieved partial response after three cycles of treatment,without severe toxicity.ELRA,anastomotic reconstruction of the middle hepatic vein,right hepatic vein,root of portal vein,inferior vena cava and right hepatic artery,and lymph node dissection were performed at one month after systemic therapy.Pathological and immunohistochemical examination confirmed the diagnosis of pCCA with lymph node metastasis.Although the middle hepatic vein was partially obstructed four months later,hepatic vein stent implantation successfully addressed this problem.The patient has survived for 22 mo after the diagnosis,with no evidence of recurrence or metastasis.CONCLUSION An effective therapeutic strategy for conversion therapy greatly increases the feasibility and efficiency of ELRA.

瓦里安23EX直线加速器维修案例分析

本文通过分析3个典型的瓦里安23EX直线加速器故障案例,阐述了医用直线加速器的结构、工作原理及维修的重要性。本文分析了HWFA联锁、AIR联锁和FLOW/PUMP联锁故障,探讨了故障原因及解决方案。直线加速器的正常运行对肿瘤放射治疗非常重要,维修工作能确保设备有效运行,避免治疗延误。定期维护和及时维修是保障设备性能的关键。