Early Intervention Facilitates Neuropsychological Development in Children with Autism and Attention Deficit Hyperactivity Disorder

Objective:This study aims to investigate the impact of early intervention on neuropsychological development in children with autism and attention deficit hyperactivity disorder(ADHD),providing effective intervention strategies for clinical practice.Methods:A total of 130 children with autism and ADHD who visited the hospital between June 2023 and June 2024 were selected as study subjects and randomly divided into an intervention group and a control group,with 65 children in each group.The intervention group received a one-year early comprehensive intervention,including behavioral therapy,cognitive training,and family guidance,while the control group only received routine medical care.The neuropsychological development assessment scale was used to evaluate both groups before and after the intervention to compare changes in their neuropsychological development levels.Results:Children in the intervention group showed significant improvements in cognitive function,social skills,language ability,and attention concentration,with an average improvement score of 23.5 points.Children in the control group did not show significant improvements in these areas,with an average improvement score of only 5.8 points.The difference between the two groups was statistically significant(P<0.05).Conclusion:Early comprehensive intervention has a significant promoting effect on the neuropsychological development of children with autism and ADHD.Targeted behavioral therapy,cognitive training,and family guidance can effectively enhance children’s cognitive,social,language,and attention abilities,laying a solid foundation for their future overall development.Therefore,it is recommended to actively promote and apply early intervention strategies in clinical practice.

Early Intervention in the Neurodevelopment of Premature Infants during the First Six Months of Life

Objective: Measure the effects of Early Intervention ad modum Katona (EI-K) in high-risk premature infants by means of clinical, neurobehavioral, and neurophysiologic tests. Method: We used the Amiel-Tison neurologic examination, the Bayley Scale of Infant Behavior, and electroencephalography (EEG) recordings at 42 weeks of conceptional age, and after 6 months of treatment EI-K (n = 14) and compared these results with those of a group of infants without early intervention (nEI) (n = 11). Results: We found better performance of infants in EI-K than nEI group after 6 months of treatment in neurologic and behavioral examination measurements, but found no differences in EEG comparisons. Conclusion: Our data suggest significant benefit of the use of EI-K program over n-EI in the neurologic and neurobe-havior examinations of premature infants after 6 months of age.

PreEMPT (Preterm Infant Early Intervention for Movement and Participation Trial): The Feasibility of a Novel, Participation-Focused Early Physiotherapy Intervention Supported by Telehealth in Regional Australia—A Protocol

Background: Early intervention is beneficial for improving preterm infant motor and cognitive outcomes in early childhood;however, little is known about whether early intervention can influence a preterm infant’s participation. Additionally, many studies investigating the impact of early intervention for preterm infants have been conducted in large metropolitan centres, leaving preterm infants who reside in regional areas underrepresented in the literature to date. Consequentially, it is not yet known whether there are service delivery models, such as using telehealth as an adjunct to face-to-face intervention, that might cater to the needs of preterm infants residing outside metropolitan centres. PreEMPT (Preterm infant Early intervention for Movement and Participation Trial) is a novel early physiotherapy intervention that has been designed to use a participation goal-directed intervention approach via a mixture of face-to-face clinic sessions and telehealth sessions to improve the motor and participation outcomes of preterm born infants. Methods: This study aims to evaluate the feasibility of PreEMPT using an assessor-blinded, randomised controlled trial to compare PreEMPT to Usual Physiotherapy Care (UPC) for preterm infants residing in a regional Australian hospital catchment area. Twenty-six preterm infants (≤34 + 6 weeks gestational age) will be recruited prior to term corrected age from the special care nursery of a regional hospital. Following informed consent and baseline assessments, infants will be randomly allocated to receive either PreEMPT, a novel participation-focused early physiotherapy intervention delivered weekly for 14 forty-five-minute sessions alternating face-to-face sessions with telehealth into the infant’s home, or UPC, two - three physiotherapy sessions in the 4-month intervention period. Outcome measures relating to infant neuromotor development, motor performance, general development, and parental mental health and well-being will be assessed at 4-, 6- and 8-months corrected age. Feasibility will be evaluated by acceptability (parental satisfaction), demand and practicality (recruitment rate and telehealth session implementation), implementation (attendance at assessment and treatment sessions), and limited efficacy testing (comparing outcomes listed above for infants in PreEMPT and UPC). Discussion: This study will be the first of its kind to use the participation of preterm infants in meaningful life situations as the foundation for intervention delivered via alternating face-to-face clinic sessions with telehealth into the home. The feasibility of this approach will be evaluated and used to inform future iterations of research about PreEMPT’s efficacy for improving preterm infant motor and participation outcomes.

Early intervention promotes intellectual development of premature infants:a preliminary report

Objective To evaluate the effect of early intervention on the intellectual development of the premature infants Methods Premature infants at gestational age of 28-36 9 weeks were randomly divided into two groups: intervention and conventional care groups Normal newborn infants during the same period were included in the control group (routine care) Up to March 1996, 156 cases were over the age 1 5-2 years (corrected age), 52 in the intervention group, 51 in the conventional care group and 53 in the normal control group Parents were taught to carry out the 0-2 year intervention program, which included motor, cognitive, speech development and social behavior Every three months, height, weight and head circumference were measured At the age of one and a half and two years, all infants in the three groups received infant development tests of Child Development Center of China (CDCC) scale The examiner did not know which infant had received intervention Results There was no significant difference in biological factors among the two premature groups and in cultural and social factors among the three groups Intelligence tests at the age of one and a half and two years showed that the average mental development index (MDI) in the intervention group was 13 8 and 14 6 higher than those in the conventional care group and the differences were significant The psychomotor development index (PDI) was 5 2 and 4 7 higher but the differences were not significant The MDI and PDI in the intervention group and normal control were quite close, but at two years, the MDI and PDI in the intervention group were 5 7 and 7 3 higher than those in the normal control and the differences were significant (P<0 05) Compared with the normal control, the MDI in conventional care group at one and a half and two years of age were 11 5 and 8 9 lower The difference was very significant There were four cases of mental retardation, whose mental development index (MDI) was less then 70 in the conventional care group, but none in the intervention group Conclusions Early intervention can promote intellectual development of the premature infants and may be beneficial to the prevention of mental retardation Early and intensive intervention can produce better results Bringing parent's initiative into full play through deepening their understanding of the importance of early intervention is the key to success

Study on the Effect of Early Oral Motor Intervention in Preterm Infants in Neonatal Intensive Care Unit

Objective:To study the effective value of introducing the concept of early oral exercise in the process of nursing intervention for preterm infants in the neonatal intensive care unit(NICU).Methods:96 cases of preterm infants diagnosed from January 2022 to August 2022 were selected and randomly divided into two groups:the general practice group(general nursing intervention),and the early practice group(early oral exercise intervention),and the effect of intervention on preterm infants in the two groups was observed.Results:After nursing care,the mean value of the non-nutritive sucking ability assessment(76.54±5.82),the mean value of the intellectual development degree assessment(104.57±8.45),the mean value of the psychomotor development degree assessment(102.33±6.74),and the mean value of behavioral neural reflexes ability assessment(38.71±2.40)in the early practice group were better than that as compared to the general practice group(P<0.05);the mean value of oral feeding start time of preterm infants in the early practice group(35.42±7.63)weeks,the mean value of all oral feeding time(34.12±5.28)weeks,and the mean time of hospital intervention(15.33±4.25)days were lesser than compared to those of the general practice group at 37.4±5.82 weeks,37.46±3.55 weeks,and 20.46±2.91 days,respectively(P<0.05);the rate of adverse reactions in preterm infants in the early practice group significantly lower than that of the general practice group(P<0.05).Conclusion:The introduction of the concept of early oral exercise intervention among NICU nurses improved the feeding effect,sucking ability of preterm infants,and intellectual development.Hence,early oral motor care should be popularized.

Effect of Community Interventions on Intelligence Development of Infants

Objective To assess the interventions effect on intelligence of the infants through the community. Methods A total of 309 newborns and their families were recruited in Xuhui district, Shanghai. They were asked to fill out the baseline questionnaires. The newborns＇ intelligence quotients were measured by Developmental Screening Test for Child Under Six, and physical examinations were conducted at the same time. The newborns were randomly assigned to intervention group （156 cases） and control group （153 cases）. The infants and their families were followed up every 6 months. A questionnaire of follow-up was completed by face-to-face interview at the communities and infant intelligence quotients were measured and had their physical check-ups again at the end of the 6th month. Results After 6 months＇ intervention, the means of MI and DQ in the intervention group were respectively 5.96 and 9.80 higher than those in control group after adjustment of the baseline scores. Conclusion Early intelligence education in the community may promote the intelligence development of infants.

Factors influencing parent satisfaction with preventive health services for the early detection of speech and language delay in preschool children

The aim of this study was to identify parent and child characteristics which could influence parent satisfaction with preventive health services designed to detect preschool children with speech and language (SL) delay. This study was conducted on 101 children aged 18 to 36 months who participated in an organized SL delay early detection program. Validated instruments were used to assess children’s and parents’ characteristics. Satisfaction was evaluated using the client satisfaction questionnaire for the three activities of the program: 1) a public information session about SL development, 2) parent training sessions for parents concerned by their child SL development, and 3) a child’s SL assessment. Multiple logistic regressions were used to identify all independent factors (p < 0.05) associated with satisfaction and to estimate the odds ratios (OR) for satisfaction. Economically disadvantaged parents were less prone to participate in the first two activities of the early detection program. Older parents were more satisfied with the public information session (OR = 1.33 for 1 year increment;p = 0.001). Distressed parents were less satisfied with both the parent training sessions (OR = 0.28;p = 0.009) and the SL assessment (OR = 0.43;p = 0.046). Parents whose child had health problems at birth were less satisfied with the public information session (OR = 0.14, p = 0.03) and the SL assessment (OR = 0.33, p = 0.036). There is a need to better adapt the delivery of preventive services for the early detection of SL delay, especially for disadvantaged and distressed parents and for those whose child had suffered from health problems at birth.

Overview of Intervention Programs for Parents of Young Children (0 - 6)

In most of the world’s societies and cultures, the biological mother and father bear primary responsibility to?care for their child’s needs and to guide him or her through the process of entry into society [1]. The parent serves, for the most part, as the significant figure with the greatest amount of influence over the child’s life. Through his parent, the child learns the skills necessary to experience the world and function in it, whether the skills are in relation to survival needs such as eating, washing and mobility or developmental and social needs such as forming social relationships and developing the capacity to think and learn through play and supervision [2]. Thus the parent plays a critical but complex role in the development of his or her child, a role that requires development of a wide range of new behavioral, communicational, cognitive and emotional skills and capabilities in order to understand and cope with the challenges of child-rearing. Similarly, parenting styles and characteristics are influenced by a number of variables: The parent, the child, the interaction between them, and environmental variables such as culture, socio-economic status, and the existing family unit [2]. When children who suffer from behavioral difficulties do not receive the parental care they need, there is reasonable cause for concern that difficulties will develop in adulthood in a range of life areas that will have an impact on their lives and well-being and on their ability to adapt to society and contribute to it [3]. Accordingly, over the past 50 years parent-training programs have been developed to strengthen parents through learning and providing tools of experience and developmental knowledge, for the purpose of promoting the child’s sense of wellbeing and quality of life [2] [4]. Objective: The purpose of this review is to provide an overview of evidence-based interventions for parents of young children (0 - 6), programs that are currently active in Israel and in the world, and to explicate the significant characteristics common to them that contribute to their effectiveness and success.

早期家庭康复干预对单调性扭动运动早产儿神经行为发育的影响

目的 探讨早期家庭康复干预对单调性扭动运动早产儿神经行为发育的影响。方法 选取2022年4月至2023年1月河北省唐山市妇幼保健院儿童康复科全身运动评估结果为单调性扭动运动的64例早产儿为研究对象。按照随机数字表法将其分为干预组和对照组,各32例。对照组给予常规家庭护理干预,干预组实施早期家庭康复干预,持续12周。比较两组干预后不安运动阶段结果;比较两组干预前后各能区发育商。结果 两组不安运动阶段结果比较,差异无统计学意义(P>0.05)。干预后,两组各能区发育商均高于干预前,且干预组大运动、个人-社交行为发育商高于对照组(P<0.05)。结论 对单调性扭动运动早产儿应用早期家庭康复干预可以有效改善大运动、个人-社交行为,值得临床推广应用。

全身运动质量评估风险分级干预策略对低出生体重儿神经发育的影响

目的 研究全身运动质量评估(GMs)不同风险分级干预对低出生体重儿在纠正6、12个月龄神经发育的影响。方法 选取新生儿科住院接受全身运动质量评估的低出生体重儿150例,出院后在门诊复评GMs。150例早产儿按GMs 2个阶段的评估结果分为高风险Ⅰ级、中风险Ⅱ级、低风险Ⅲ级,制定不同早期干预策略,比较3组患儿纠正6、12个月龄神经发育结果及纠正12个月龄时神经发育结局。结果 纠正6个月龄3组患儿龄精细动作、社会适应、语言、个人社交行为4个领域发育商评分比较,差异均有统计学意义(P<0.05)。纠正12个月龄3组患儿在粗大运动、精细运动、社会适应、语言、个人社交行为5个领域商评分比较,差异有统计学意义(P<0.01)。纠正12个月龄,神经发育结局异常9例,其中脑性瘫痪1例(高风险Ⅰ级),运动发育迟缓8例(高风险Ⅰ级2例、中风险Ⅱ级4例、低风险Ⅲ级2例)。结论 应用GMs评估结果不同风险分级精细化管理指导。能够促进低出生体重儿神经发育,减少神经发育异常,可在临床工作中进一步推广和应用。

爬行真的可有可无吗?——婴幼儿动作发展的国际论证与经验启示

动作发展是指个体在成长过程中逐渐掌握并发展出的各种动作技能。爬行在婴幼儿动作发展中扮演着重要角色,对认知神经系统、肌肉骨骼系统、动作能力和社交能力等方面的成长发育有着积极意义。然而,我国学术界对于动作发展,尤其是爬行的重视程度相对较低,且公众对于爬行在个体成长中的重要性认知不足。以爬行这一婴幼儿时期关键的动作发展里程碑为例,运用文献资料法和逻辑分析法,系统梳理了国际上关于婴儿爬行的相关研究,包括其发展变化、多元作用、影响因素和干预措施等方面的理论研究与实践探索。对实现我国“幼有优育”的婴幼儿健康成长的研究启示主要有:开展大样本的婴儿爬行队列研究;采用婴儿爬行经历作为临床筛查的参考指标;改善婴儿家庭养育的爬行支持环境;完善特殊婴儿的爬行活动干预。

东莞市高危儿早期干预的效果

目的 探讨东莞市高危儿早期干预的效果。方法 将2022年2—10月东莞市妇幼保健院收治的400例高危患儿纳入研究。根据双盲随机法分为早期干预组和常规育儿组,各200例。常规育儿组主要接受家庭常规干预,早期干预组主要接受家庭配合医疗部门进行早期综合干预。对比2组的干预效果、发育水平、后遗症发生率及依从性。结果 干预前,2组粗大运动功能评分比较,差异无统计学意义(P> 0.05);干预后,早期干预组粗大运动功能评分高于常规育儿组,差异有统计学意义(P <0.05)。干预前,2组发育水平比较,差异无统计学意义(P> 0.05);干预1、2个疗程后,早期干预组发育水平均高于常规育儿组,差异有统计学意义(P <0.05)。早期干预组后遗症总发生率为0.50%,低于常规育儿组的5.50%(P<0.05)。早期干预组干预总依从性为98.50%,常规育儿组干预总依从性为94.00%,早期干预组高于常规育儿组(P <0.05)。结论 早期干预可有效促进高危儿的正常发育,降低后遗症发生的风险。

促进婴幼儿健康发展的公共卫生策略述评

婴幼儿期是生长发育的关键阶段,需要充足的营养和照护,以预防未来健康风险。鉴于中国的生育现状,国家在尽快推出完善的生育支持政策的同时,还需要制定更加全面有效的儿童早期发展干预策略。文章旨在结合生命早期发育的特点,对从资源整合、政策规范、营养刺激和护理保护等方面进行全生命周期的干预措施进行评述,以期为提升儿童全面发展质量和国家的人口可持续发展提供参考和依据。

早期母乳联合母乳强化剂对极低出生体重早产儿生长发育及喂养不耐受的影响

目的探讨早期母乳联合母乳强化剂对极低出生体重早产儿生长发育及喂养不耐受的影响。方法选择2021年8月—2022年9月青岛大学附属威海市立第二医院收治的82例极低出生体重早产儿为研究对象,采用随机数字表法将其分为对照组和观察组,各41例。对照组采取早期母乳喂养,观察组在对照组基础上联合母乳强化剂喂养。比较两组的生长发育指标、营养指标、喂养不耐受情况及并发症发生情况。结果出院1年后,观察组头围、身长均长于对照组,体重大于对照组,组间差异有统计学意义(P<0.05)。喂养3个月后,观察组前白蛋白、白蛋白、总蛋白水平均高于对照组,组间差异有统计学意义(P<0.05)。出院前,观察组喂养不耐受发生率、并发症发生率均低于对照组,组间差异有统计学意义(P<0.05)。结论早期母乳联合母乳强化剂对极低出生体重早产儿进行喂养可有效改善其喂养不耐受情况,可提高早产儿的机体营养状况,并促进生长发育,且可减少并发症的发生。

早产儿语言发展的影响因素及其干预对策

早产儿的语言发展受到多种因素的影响,可能导致他们在词汇、语法、语音等方面出现发展滞后或障碍。本文首先简述了影响早产儿语言发展的生物学和环境因素的研究进展,其中生物学因素包括早产程度、体重和性别、新生儿发病率和疾病严重程度等,环境因素则包括新生儿重症监护室的环境、家庭中的语言环境和社会因素等。在明确这些影响因素的基础上,本文强调了早期评估和早期干预是优化早产儿语言发育效果的关键步骤,并分析了具体的干预对策,例如生理和神经干预、优化新生儿重症监护室(NICU)环境、增强家庭语言互动、多学科合作和社会支持等。此综述旨在探讨影响早产儿语言发展的各种因素,并总结出有效的早期干预措施,为其提供更为全面的语言发展支持。

早期干预对NICU早产儿体格及神经心理发育的效果研究

目的 探讨早期干预对于新生儿重症监护病房(NICU)早产儿两年内的体格和神经心理发育的影响。方法 选取2018年1月至2020年12月于苏州市立医院就诊的102例NICU早产儿为干预组,随机抽取105例同期健康足月儿为对照组。结果 矫正24月龄时,经早期干预的低危早产儿体重、身长以及头围的Z评分均可达到正常足月儿水平(分别为0.34±0.98、0.40±1.30和0.54±1.04,P>0.05),但是高危早产儿组的3项Z评分不及足月儿组(分别为-0.17±1.15、0.00±1.29和-0.33±1.24,P<0.05)。大运动方面,矫正6~24月龄,高危、低危早产儿均可达足月儿水平,24月龄时,高危儿组、低危儿组、足月儿组分别为101.81±10.05、02.06±10.85、100.47±9.40(P>0.05)。语言与社交行为方面,矫正18~24月龄,早产儿的发育水平可达足月儿水平。适应能力发育方面,矫正18月龄前,高危、低危早产儿适应能力水平可达足月儿,但24月龄时,早产儿适应能力水平均不及足月儿,高危儿组、低危儿组、足月儿组分别为102.77±12.04、101.73±10.34、106.78±9.31(P<0.05)。与之类似的精细运动发育,矫正12月龄时,高危、低危早产儿精细运动水平可达足月儿,18~24月龄时,高危、低危早产儿精细运动水平均不及足月儿。结论 出生后2年内高危和低危早产儿体格及神经心理发育存在差异,且高危早产儿落后尤其明显。正确认识早产儿体格及神经心理发育规律,制定个体化的早期干预模式,对早产儿的体格及神经心理发育具有重要作用。

婴儿运动表现测试联合全身运动评估及头颅磁共振成像对早产儿神经运动发育结局的预测价值

目的:探讨婴儿运动表现测试(TIMP)联合全身运动评估(GMs)及头颅磁共振成像(MRI)对早产儿神经运动发育结局的预测价值。方法:选取125例早产高危儿作为研究对象。对所有纳入对象在纠正胎龄40周时进行TIMP测试,在纠正胎龄46~56周时进行GMs测试,并在期间进行头颅MRI检测。对所有研究对象随访1年,并记录神经运动发育不良结局发生情况。比较三种检测方式的结果及预测准确度,采用Kappa法进行一致性分析,并采用受试者工作特征曲线(ROC)分析各检测方式对早产儿神经运动发育结局的预测价值。结果:共发生17例不良结局,其中4例脑瘫,13例神经运动发育迟缓,不良结局发生率为13.60%。TIMP测试结果、GMs测试、MRI检测结果均与神经发育结局相比一致性一般(0.4≤Kappa<0.75,P<0.05)。GMs测试的阳性预测率高于TIMP及三者联合检测,MRI检测的阳性预测率高于TIMP及三者联合检测(P<0.05)。三者联合检测的阴性预测率高于GMs测试(P<0.05)。TIMP、GMs、MRI与三者联合检测之间的准确度相比无统计学差异(P>0.05)。经ROC曲线分析得知,TIMP测试的AUC为0.872,敏感度为0.882,特异度为0.861;GMs测试的AUC为0.755,敏感度为0.529,特异度为0.981;MRI的AUC为0.839,敏感度为0.706,特异度为0.972;三者联合检测的AUC为0.931,敏感度为1.000,特异度为0.861。结论:TIMP、GMs及头颅MRI检测在预测早产儿神经运动发育结局方面均具有较高的预测价值,三者联合应用可提高对早产儿并发神经运动不良结局的预测价值。

早期认知语言康复训练对脑损伤早产儿临床症状改善、脑功能发育状况及病情转归的影响

目的:探讨早期认知语言康复训练联合康复治疗对脑损伤早产儿临床症状改善、脑功能发育状况及病情转归的影响。方法:选取130例脑损伤早产儿为研究对象,按干预方案不同分为观察组(n=65)及对照组(n=65)。对照组给予常规康复治疗;观察组在对照组的基础上给予早期认知语言康复训练,持续干预12个月。比较两组患儿干预第3、6、9、12个月贝利婴幼儿发展量表(BSID)评分及干预第6个月、12个月的Gesell发育量表评分,比较两组患儿干预前后振幅整合脑电图最高电压、最低电压水平,观察患儿后遗症发生情况。结果:随着时间推移,两组BSID量表智力发育指数(MDI)、心理运动发育指数(PDI)评分均升高(P<0.05),且观察组均高于对照组(P<0.05);随着时间推移,两组Gessell量表大运动、精细运动、语言、适应性、个人社交DQ评分均升高(P<0.05),且观察组均高于对照组(P<0.05);干预第12个月,观察组振幅整合脑电图最高电圧、最低电压均高于对照组(P<0.05);观察组后遗症发生率为12.31%,低于对照组的26.15%(P<0.05)。结论:在常规康复治疗的基础上联合应用早期认知语言康复训练可有效提高脑损伤早产儿智能发育水平,促进其损伤神经系统修复,降低后遗症风险,改善患儿预后。

穴位刺激结合早期口腔运动干预对经口喂养困难早产儿的影响

目的:探讨穴位刺激结合早期口腔运动干预对经口喂养困难早产儿吸吮技能及生长发育的影响。方法:将2020年9月1日~2021年6月30日收治的120例经口喂养困难早产儿按照随机数字表法分为对照组和观察组各60例,对照组给予常规护理,观察组在常规护理基础上给予穴位刺激结合早期口腔运动干预,直至早产儿完全经口喂养;比较两组不同时间经口喂养能力[采用早产儿经口喂养准备量表(PIOFRA)]、吸吮功能变化[采用口腔运动评估量表(NOMAS)],经口喂养进程、体重增长情况、神经系统发育情况。结果:干预后,两组PIOFRA中胎龄矫正、口腔姿势、口腔反射、行为状态、非营养性吸吮评分均高于干预前(P<0.05),且观察组高于对照组(P<0.05,P<0.01);完全经口喂养时(T2),观察组正常型、失调型及障碍型评分均低于对照组(P<0.05,P<0.01);观察组完全经口喂养时间短于对照组(P<0.01),每日摄入奶量占比及喂养效率均高于对照组(P<0.01);观察组住院期间体重增长高于对照组(P<0.01);观察组6月龄时神经系统发育正常例数占比高于对照组(P<0.05),发育异常例数占比低于对照组(P<0.05)。结论:穴位刺激结合早期口腔运动干预能够提高经口喂养困难早产儿经口喂养能力及吸吮功能,改善经口喂养进程及效率,有利于早产儿体重的增长及神经运动系统发育。

早期抚触联合捏脊配合袋鼠式护理对早产儿生长发育及环境适应的影响

目的探究采用早期抚触联合捏脊干预配合袋鼠式护理方法运用于早产儿进行护理干预后对患儿生长发育及环境适应的影响及效果。方法选择我院于2021年3月至2023年4月期间收治进行住院治疗的早产儿进行对照性研究,共有研究对象80例,将80例早产儿随机分组,即对照组(40例)与观察组(40例)。对照组早产儿在治疗期间采用常规护理措施,观察组早产儿则在常规护理措施的基础上添加进行早期抚触联合捏脊配合袋鼠式护理。结果观察组早产儿在生长发育方面与对照组早产儿比较,其结果明显较好,P<0.05;观察组早产儿的营养状况明显好于对照组,P<0.05;观察组早产儿的发育商(DQ)评分显著高于对照组,P<0.05。结论早期抚触联合捏脊干预配合袋鼠式护理对早产儿护理干预后,疗效明显,可有效促进患儿的生长发育,同时可有效提高患儿喂养耐受性,有效促进进食和发育,对改善早产儿营养情况及机体抵抗力、免疫力,环境适应均具有重要意义,并能提高神经发育和环境适应性,为早产儿提供安全有益的治疗手段,具有较高的临床推广价值。