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Progress in controlling rice blast disease and its prospect in early 21^(st) century
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《Chinese Rice Research Newsletter》 2000年第3期11-13,共3页
关键词 st CENTURY Progress in controlling rice blast disease and its prospect in early 21
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Atrial fibrillation and coronary artery disease:An integrative review focusing on therapeutic implications of this relationship 被引量:3
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作者 Akash Batta Juniali Hatwal +2 位作者 Akshey Batta Samman Verma Yash Paul Sharma 《World Journal of Cardiology》 2023年第5期229-243,共15页
The incidence of both atrial fibrillation(AF)and coronary artery disease(CAD)increases with advancing age.They share common risk factors and very often coexist.Evidence points to an intricate relationship between atri... The incidence of both atrial fibrillation(AF)and coronary artery disease(CAD)increases with advancing age.They share common risk factors and very often coexist.Evidence points to an intricate relationship between atrial tissue excitability and neuronal remodeling with ischemia at the microcirculatory level.In this review,we delineated this complex relationship,identified a common theme between the two,and discussed how the knowledge of this relationship translates into a positive and meaningful impact in patient management.Recent research indicates a high prevalence of CAD among AF patients undergoing coronary angiography.Further,the incidence of AF is much higher in those suffering from CAD compared to age-matched adults without CAD underlying this reciprocal relationship.CAD adversely affects AF by promoting progression via re-entry and increasing excitability of atrial tissue as a result of ischemia and electrical inhomogeneity.AF in turn accelerates atherosclerosis via endothelial dysfunctional and inflammation and together with enhanced thrombogenicity and hypercoagulability contribute to micro and macrothrombi throughout cardiovascular system.In a nutshell,the two form a vicious cycle wherein one disease promotes the other.Most AF recommendations focuses on rate/rhythm control and prevention of thromboembolism.Very few studies have discussed the importance of unmasking coexistent CAD and how the treatment of underlying ischemia will impact the burden of AF in these patients.Inflammation and endothelial dysfunction remain central to both disease processes and form a handsome therapeutic target in the management of the two diseases.The relationship between AF and CAD is complex and much more than mere coincidence.The two diseases share common risk factor and pathophysiology.Hence,it is impractical to treat them in isolation.Accordingly,we share the implications of managing underlying ischemia and inflammation to positively impact and improve quality of life among AF patients. 展开更多
关键词 Atrial fibrillation Coronary artery disease Antithrombotic therapy ISCHEMIA early rhythm control Endothelial dysfunction
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Numerical simulation and disaster prevention for catastrophic fire airflow of main air-intake belt roadway in coal mine—A case study 被引量:8
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作者 周刚 程卫民 +4 位作者 张睿 沈宝堂 聂文 张磊 王昊 《Journal of Central South University》 SCIE EI CAS CSCD 2015年第6期2359-2368,共10页
Coal mine belt fire develops very rapidly and is difficult to control. If not suppressed quickly, a belt fire could easily lead to airflow disorder and undermine the ventilation system. However, belt fire can be preve... Coal mine belt fire develops very rapidly and is difficult to control. If not suppressed quickly, a belt fire could easily lead to airflow disorder and undermine the ventilation system. However, belt fire can be prevented effectively by establishing fire airflow control system. In this work, the 5th belt roadway of Kongzhuang coal mine was taken as the object of investigation, where geometrical models of this roadway were established firstly. Then, based on mathematical model of fire smoke flow, the CO volume fraction, smoke density distribution, air temperature and pollutant velocity vector in the roadway before and after taking airflow control measures were simulated by using Fluent software. It can be known from the simulation that with the normal ventilation status in 5th belt roadway, the countercurrent of smoke does not happen when a fire occurs; the roadway's section is almost filled with CO at 10 m downstream from the fire source, and with air velocity getting stable gradually, the CO concentration reaches about 15 %. After taking airflow control measures, the effect range of temperature field which are harmful to the miners decreases from 69 m to 30 m; and the distance of the roadway fully filled with CO is 5 m farther than that before taking measures. Finally, according to the numerical simulation results and the actual condition of the belt roadway, the warning and automatic remote airflow control system with short-circuit method for the 5th belt roadway was designed to guarantee the safety production. 展开更多
关键词 belt roadway fire catastrophic airf ow numerical simulation flow pattern early warning and control
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Effect of soothing-liver and nourishing-heart acupuncture on early selective serotonin reuptake inhibitor treatment onset for depressive disorder and related indicators of neuroimmunology:a randomized controlled clinical trial 被引量:15
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作者 Liu Yi Feng Hui +6 位作者 Mo Yali Gao Jingfang Mao Hongjing Song Mingfen Wang Shengdong Yin Yan Liu Wenjuan 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2015年第5期507-513,共7页
OBJECTIVE:To observe the effect of soothing-liver and nourishing-heart acupuncture on selective serotonin reuptake inhibitor(SSRIs) treatment effect onset in patients with depressive disorder and related indicators of... OBJECTIVE:To observe the effect of soothing-liver and nourishing-heart acupuncture on selective serotonin reuptake inhibitor(SSRIs) treatment effect onset in patients with depressive disorder and related indicators of neuroimmunology.METHODS:Overall,126 patients with depressive disorder were randomly divided into a medicine and acupuncture-medicine group using a random number table.Patients were treated for 6 consecutive weeks.The two groups were evaluated by the Montgomery-Asberg Depression Rating Scale(MADRS) and Side Effects Rating Scale(SERS) to assess the effect of the soothing-liver and nourishing-heart acupuncture method on early onset of SSRI treatment effect.Changes in serum 5-hydroxytryptamine(5-HT) and inflammatory cytokines before and after treatment were recorded and compared between the medicine group and the acupuncture-medicine group.RESULTS:The acupuncture-medicine group had significantly lower MADRS scores at weeks 1,2,4,and 6 after treatment compared with the medicine group(P < 0.01).The acupuncture group had significantly lower SERS scores at weeks 1,2,4,and 6 after treatment compared with the medicine group(P < 0.01).At 6 weeks after treatment,serum 5-HT in the acupuncture-medicine group was significantly higher compared with the medicine group(P <0.01).lnterleukin-6(IL-6) in the acupuncture-medicine group was significantly lower than that in the medicine group(P < 0.01),whereas there was no significant difference in IL-1(3 between the groups(P > 0.05).Anti-inflammatory cytokines IL-4 and IL-10 were significantly higher in the acupuncture-medicine group compared with the medicine group(P < 0.01,P < 0.05,respectively).CONCLUSION:The soothing-liver and nourishing-heart acupuncture method can effectively accelerate the onset of SSRI effects when treating depressive disorder and can significantly reduce the adverse reactions of SSRIs.Moreover,acupuncture can enhance serum 5-HT and regulate the balance of pro-inflammatory cytokines and anti-inflammatory cytokines. 展开更多
关键词 Acupuncture Soothing-liver and nourishing-heart method early onset Serotonin uptake inhibitors Depressive disorder Serotonin Inflammatory cytokines Randomized controlled trial
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