Can Physical Activities Suppress Negative Impact of Stress on the Mental Health of Adolescents?

Early adolescence is a crucial developmental phase marked by significant physical,cognitive,and socioemotional changes.While stress is widely recognized as a notable risk factor during this period,not all individuals experiencing stress concurrently manifest compromised mental health.The association between stress and mental health outcomes is influenced by individual differences in characteristics and coping strategies.This study’s purpose was to assess the negative impact of stress on mental health,specifically focusing on symptoms of anxiety,depression,and psychological distress.Additionally,the research investigates whether different levels of physical activity can suppress the negative effects of stress.A total of 212 upper elementary school students(52.8%girls and 47.2%boys)from rural and urban areas voluntarily participated in the research.Participants online self-assessed on several measures:The Young Person’s CORE,Children’s Anxiety Scale,Children’s Depression Inventory,School Stress Intensity Scale for Students,and Physical Activity Questionnaire for Older Children.The results revealed a significant increase in adolescents experiencing impaired mental health.More than two-thirds(67.5%)of students self-assessed significant symptoms of depression,additionally,57.5%of them had significant symptoms of psychological distress,and 27.8%had significant symptoms of anxiety.Stress demonstrated a significant direct negative effect,leading to increased symptoms of anxiety(t=5.35,p=0.00)and psychological distress(t=4.29,p=0.00);however,there was no significant influence on depression(t=1.33,p=0.18)).Regarding regular physical activity,a significant moderating effect was identified,effectively suppressing the negative impact of stress on anxiety(F=3.88(2,206);p=0.02).In contrast,no significant moderation effect of physical activity was found for symptoms of depression(F=1.45(2,206);p=0.24)and psychological distress(F=1.14(2,206);p=0.32),highlighting a complex and intricate association between physical activity and various mental health outcomes.In conclusion,the practical implications of this study emphasize the importance of creating environments that reduce stressors for adolescents and promote regular physical activity as a means of fostering positive mental health outcomes.

Study of the intensive care unit activity scale in the early rehabilitation of patients after direct cardiac surgery

BACKGROUND Direct cardiac surgery often necessitates intensive post-operative care,and the intensive care unit(ICU)activity scale represents a crucial metric in assessing and guiding early rehabilitation efforts to enhance patient recovery.AIM To clarify the clinical application value of the ICU activity scale in the early recovery of patients after cardiac surgery.METHODS One hundred and twenty patients who underwent cardiac surgery between September 2020 and October 2021 were selected and divided into two groups using the random number table method.The observation group was rated using the ICU activity scale and the corresponding graded rehabilitation interventions were conducted based on the ICU activity scale.The control group was assessed in accordance with the routine rehabilitation activities,and the postoperative rehabilitation indexes of the patients in both groups were compared(time of tracheal intubation,time of ICU admission,occurrence of complications,and activity scores before ICU transfer).The two groups were compared according to postoperative rehabilitation indicators(time of tracheal intubation,length of ICU stay,and occurrence of complications)and activity scores before ICU transfer.RESULTS In the observation group,tracheal intubation time lasted for 18.30±3.28 h and ICU admission time was 4.04±0.83 d,which were significantly shorter than the control group(t-values:2.97 and 2.038,respectively,P<0.05).The observation group also had a significantly lower number of complications and adverse events compared to the control group(P<0.05).Before ICU transfer,the observation group(6.7%)had few complications and adverse events than the control group(30.0%),and this difference was statistically significant(P<0.05).Additionally,the activity score was significantly higher in the observation(26.89±0.97)compared to the control groups(22.63±1.12 points)(t-value;-17.83,P<0.05).CONCLUSION Implementation of early goal-directed activities in patients who underwent cardiac surgery using the ICU activity scale can promote the recovery of cardiac function.

The Effect of Early versus Traditional Hospital Discharge on Activities of Daily Living for Women Undergoing Elective Cesarean Section. An Observational Cohort Study

Background: Cesarean section is one of the most common surgeries performed worldwide and its consequences and complications represent a major public health concern. The policy of enhanced recovery after surgery has been implemented after cesarean section to optimize perioperative care. Enhanced recovery also aims to reduce the length of hospital stay, which might imply substantial healthcare savings. Rising hospital costs are one of the factors in early discharge. Patients & Methods: This was a prospective cohort study. 158 patients met the inclusion criteria of the study, 81 patients were discharged after 48 hours and 77 patients were discharged after 24 hours. All patients received the same postoperative care and instructions. All the study participants received a phone call 1, 3, and 5 days after discharge to objectively assess the activities of daily living through Katz index of independence in activities of daily living. All patients were offered a postpartum visit 1 week after discharge during which the wound was assessed by the Southampton wound assessment scale. Moreover, other maternal complications such as mastitis, puerperal sepsis, or pyelonephritis were assessed and cases who were readmitted were documented. Initiation of successful breastfeeding and neonatal readmission were reported as well. Results: 158 patients met the inclusion/exclusion criteria of the study. There was no significant difference between the two arms of the study regarding baseline characteristics. Katz index of independence showed that the resumption of activities of daily living after CS was similar in both arms of the study on days 1, 3 and 5 after discharge. Time till the passage of flatus and stool after the cesarean section was significantly shorter among the early discharge arm (9.31 VS 14.68, p value < 0.001 & 13.25 VS 24.82, p value < 0.001 respectively). Maternal readmission was not significantly higher among the early discharge arm and at the 1-week postpartum visit, objective wound assessment by Southampton wound scoring assessment was made and there was no significant difference between the two arms of the study. Initiation of successful breastfeeding, and neonatal readmission were similar in both groups. Conclusion: The policy of early discharge can be adopted in low-risk cases scheduled for elective uncomplicated CS provided that the mother and the neonate are in good general condition and proper instructions regarding red flag manifestations are given.

Chronic active and atrophic gastritis as significant contributing factor to the development of gastric cystica profunda

Gastric cystica profunda(GCP)is an uncommon but underestimated gastric lesion.Its precancerous potential determines its significance.In addition to previous mucosa injury due to operations,biopsy or polypectomy,chronic active and atrophic gastritis may also lead to the development of GCPs.By carefully examining the stomach and taking biopsy samples from the susceptible regions,the stage of atrophy can be determined.Chronic atrophic gastritis is a risk factor for cancer evolvement and it can also contribute to GCPs formation.GCPs frequently occur close to early gastric cancers(EGCs)or EGC can arise from the cystic glands.Endoscopic resection is an effective and minimally invasive treat-ment in GCP.

Progress in the Early Mobilization of Patients after Cardiac Intervention

Early activity has a positive effect on the rehabilitation process of patients after cardiac intervention. This paper summarizes the concept and significance of early activity after cardiac intervention, the best time and mode of different types of early activity after cardiac intervention, and the factors affecting early activity, aiming to provide a basis for clinical medical staff to provide safe and effective guidance of early activity after cardiac intervention.

Association between fundamental motor skills and physical activity in the early years:A systematic review and meta-analysis

Background:Physical activity(PA)in the early years is associated with a range of positive health outcomes.Fundamental motor skill(FMS)competence is associated with PA and is theorized to be driven by PA in the early years and vice versa in mid to late childhood.However,to date,no studies have meta-analyzed the association between PA and FMS in the early years.Methods:Six electronic databases were searched for articles published up to April 2019.Cross-sectional and longitudinal studies were included if they targeted children(ages 3-6 year)as the population of the study and assessed the association between objectively measured PA and FMS.Total FMS,total physical activity(TPA),and moderate-to-vigorous physical activity(MVPA)data were meta-analyzed using a random effects model.Results:We identified 24,815 titles and abstracts.In total,19 studies met the inclusion criteria,including 14 cross-sectional and 4 longitudinal studies,as well as 1 study with cross-sectional and longitudinal analysis.There was a significant but small positive association between FMS and MVPA(r=0.20,95%confidence interval(CI):0.13-0.26)and TPA(r=0.20,95%CI:0.12-0.28).Findings from longitudinal studies revealed that PA drives FMS in early childhood.Mediation was explored in 1 study,which found that perceived motor competence did not mediate the association between FMS and PA.Conclusion:Using a meta-analysis,this study is the first to show a positive association between FMS,MVPA,and TPA in the early years of childhood,suggesting that the association begins at an early age.Limited evidence from longitudinal studies supports the theory that PA drives FMS in the early years of childhood.More evidence is needed from large studies to track PA and FMS until mid to late childhood and to explore the mediators of this association.

Classification of Northeast China Cold Vortex Activity Paths in Early Summer Based on K-means Clustering and Their Climate Impact

The classification of the Northeast China Cold Vortex(NCCV)activity paths is an important way to analyze its characteristics in detail.Based on the daily precipitation data of the northeastern China(NEC)region,and the atmospheric circulation field and temperature field data of ERA-Interim for every six hours,the NCCV processes during the early summer(June)seasons from 1979 to 2018 were objectively identified.Then,the NCCV processes were classified using a machine learning method(k-means)according to the characteristic parameters of the activity path information.The rationality of the classification results was verified from two aspects,as follows:(1)the atmospheric circulation configuration of the NCCV on various paths;and(2)its influences on the climate conditions in the NEC.The obtained results showed that the activity paths of the NCCV could be divided into four types according to such characteristics as the generation origin,movement direction,and movement velocity of the NCCV.These included the generation-eastward movement type in the east of the Mongolia Plateau(eastward movement type or type A);generation-southeast longdistance movement type in the upstream of the Lena River(southeast long-distance movement type or type B);generationeastward less-movement type near Lake Baikal(eastward less-movement type or type C);and the generation-southward less-movement type in eastern Siberia(southward less-movement type or type D).There were obvious differences observed in the atmospheric circulation configuration and the climate impact of the NCCV on the four above-mentioned types of paths,which indicated that the classification results were reasonable.

Observation of early active training effects after the operation for lumber intervertebral disc herniation

Objective To explore the recent and distant effects of early active training after the operation for lumber intervertebral disc herniation.Method 79 patients after the operation for mono segmental lumber intervertebral disc herniation had been divided into early active training group and routine control group randomly, and accepted training, regular re-examination, and follow-up of 1～6 years respedtively.Results The early active training group had better recent and distant objective effect, and more patients (97.6%) were satisfied with the operational effects.Conclusions The early active training after the operation for lumber intervertebral disc herniation is positive significant for operational effects.

A new early-warning prediction system for monitoring shear force of fault plane in the active fault

The most common method used to describe earthquake activity is based on the changes in physical parameters of the earth＇s surface such as displacement of active fault and seismic wave.However,such approach is not successful in forecasting the movement behaviors of faults.In the present study,a new mechanical model of fault activity,considering the shear strength on the fault plane and the influence of the resistance force,is established based on the occurrence condition of earthquake.A remote real-time monitoring system is correspondingly developed to obtain the changes in mechanical components within fault.Taking into consideration the local geological conditions and the history of fault activity in Zhangjiakou of China,an active fault exposed in the region of Zhangjiakou is selected to be directly monitored by the real-time monitoring technique.A thorough investigation on local fault structures results in the selection of two suitable sites for monitoring potential active tectonic movements of Zhangjiakou fault.Two monitoring curves of shear strength,recorded during a monitoring period of 6 months,turn out to be steady,which indicates that the potential seismic activities hardly occur in the adjacent region in the near future.This monitoring technique can be used for early-warning prediction of the movement of active fault,and can help to further gain an insight into the interaction between fault activity and relevant mechanisms.

Autonomic Nervous Activity in Multiparous Women during Early Postpartum Period: A Descriptive Study

Background: The purpose of the present study is to analyze the autonomic nervous activity in multiparas while resting, nursing, and rooming-in/rooming-out during days 1 to 3 of early postpartum period. Methods: Subjects were asked to record the actions they performed while wearing a heart rate monitor. Changes in autonomic nervous activity from 9 am to 12 pm and relaxation based on the relaxation (RE) scale were surveyed in multiparous women experiencing a normal postpartum period, on postpartum days 1 to 3. Results: Thirteen subjects were enrolled but heart rate data for all 3 days were available for only 5 of them. In these patients, the autonomic nervous activity (heat rate, high frequency [HF], or low frequency [LF]/HF) showed no significant differences between the days during any of the time periods. However, of the 3 days, day 2 demonstrated a lower HF and higher LF/HF. Subjective sense of relaxation was higher on postpartum day 3 compared to days 1 and 2, but there was no significant difference observed in the 3-day total score. Though no significant differences in HF and LF/HF at rest and during nursing were observed for any of the 3 days, there was a tendency for HF to be lower and LF/HF to be higher during nursing than at rest. Conclusions: Autonomic nervous activity demonstrated no significant major changes between the 3 days of postpartum (day 1 to 3). However, the lower HF and higher LF/HF during nursing and rooming-in suggest that even multiparas, who are supposedly accustomed to nursing and child-rearing, can be tense. Results suggest that multiparas require monitoring, personal care, and attention so that they can be relaxed and less tense while nursing and caring for their children.

矿井微震与电法耦合监测技术

随着煤炭资源开采区域、深度及强度的增加,矿井工作面采掘扰动极易诱发矿井突水事故,严重威胁我国煤炭资源安全开采。矿井水害事故的发生主要是岩体采动破裂与矿井水渗流共同作用的结果。研究表明,微震信号的纵横波到时、幅值、频率等参量可有效表征岩体破裂位置、强度及其震源机制,地电场信号中的电阻率、激励电流及自然电位等参量可有效表征岩体渗流演化过程。透水通道形成对应微震场特征,地下水渗流对应地电场特征,因此微震电法耦合方法对矿井水害孕育发展过程具有监测预警的功能,可有效对采动破坏过程中形成的突水通道、水源位置及渗流过程等水害三要素进行精准捕捉;减少单一地球物理方法多解性,提高水害监测预警精度,对煤矿防治水意义重大。当前,微震与电法耦合监测技术在煤矿水害实时动态监测中开始得到应用,突破传统微震与电法独立采集的局限,课题组自主研发了国内外首款煤安认证的微震与电法耦合并行监测系统,该系统以微震场与地电场并行采集基站为核心,集被动源微震波场与主被动地电场为一体,通过连接矿井物联网,实现远程数据采集控制、传输及云端存储;其一体化网络服务器主机可连接多个采集基站,并将微震检波器、电法激励电极与电位测量电极进行相互隔离、并行采集,形成微震事件密度与能级分布、电阻率分布、自然电位分布等时空云图来监测预判水害三要素。微震与电法耦合监测技术仍需在微震事件智能识别与定位、地电场的电阻率三维反演以及自然电位渗流反演方面进行专项攻关;结合并行监测的微震电法大数据集,重点在微震电法数据联合反演、智能化监测预警方向开展进一步研究。微震与电法耦合监测技术,作为矿井水害的主动预警监测新方法,可为我国智能化矿井建设发挥重要作用。

危重症患儿早期活动的最佳证据总结

目的对危重症患儿早期活动的最佳证据进行整理总结,为临床制定相关干预策略提供参考。方法通过检索加拿大安大略省注册护士协会网(RNAO)、英国国家卫生与临床优化研究所(NICE)、苏格兰学院间指南网络(SIGN)、Web of Science、Cochrane Library、PubMed、Best Practice(BMJ)、UpToDate、中国生物医学文献服务系统、万方数据知识服务平台、中国知网等数据库中危重症患儿早期活动的相关文献,检索时限为建库至2023年8月14日,按照JBI循证卫生保健中心的相应评价标准进行质量评价,对纳入的文献进行证据提取。结果最终纳入文献10篇,提取内容包括团队、评估、绝对禁忌、相对禁忌、运动状况监测和活动内容6个维度共20条最佳证据。结论提取的危重症患儿早期活动的最佳证据可作为重症患儿早期活动的循证依据。

多学科模式下ICU机械通气患者早期活动协作现状与影响因素分析

目的:了解在国内多学科模式下,ICU机械通气患者早期活动的协作现状,分析其影响因素。方法:2022年10月—11月,便利抽取国内18个省、自治区、直辖市的31家三级综合医院参与ICU机械通气患者早期活动实施的多学科医务人员,采用自设的ICU机械通气患者早期活动多学科协作现状调查问卷调查。结果:在554名医务人员中,有76.9%完全不了解或不太了解ICU机械通气患者早期活动多学科协作的规范流程,有69.0%不清楚自己在多学科协作中的职责,有51.4%所在的ICU没有成立明确的早期活动多学科团队。回归分析显示,管理危重患者数量、有无早期活动规范和流程、周围同事态度、是否成立多学科团队、成员沟通方式、活动主导者为早期活动多学科医务人员协作水平的影响因素(P<0.05)。结论:多学科模式下,ICU机械通气患者早期活动的协作方式尚不清晰,需要综合考虑我国医护人力资源现状、各地区经济水平等,构建并完善早期活动的多学科协作策略。

基于快速康复外科理念的四级早期活动对心脏瓣膜置换术后谵妄发生的预防

目的探讨基于快速康复外科理念的四级早期活动对预防心脏瓣膜置换术后谵妄发生的效果。方法选取新疆医科大学第一附属医院2020年11月至2022年7月拟行心脏瓣膜置换术治疗的患者100例进行研究。通过随机数字表法将其分为对照组和观察组,各50例。对照组接受常规护理措施,观察组在对照组基础上给予基于快速康复外科理念的四级早期活动。采用重症监护谵妄筛查量表评估两组术后7 d内谵妄发生情况;记录谵妄首次发生时间及持续时间;比较两组住院时间及机械通气时间。结果术后7 d内,对照组共发生谵妄26例,占比52%;观察组共发生谵妄16例,占比32%。观察组谵妄发生率低于对照组,差异有统计学意义(P<0.05);观察组谵妄首次发生时间、谵妄持续时间均短于对照组,差异有统计学意义(P<0.05);观察组住院时间短于对照组,差异有统计学意义(P<0.05)。结论基于快速康复外科理念的四级早期活动可减少心脏瓣膜置换术患者术后谵妄发生,缩短谵妄持续时间,减少谵妄相关不良事件的发生,缩短住院时间。

脑血管造影术后使用股动脉压迫止血器患者早期活动的循证实践

目的基于最佳证据制定脑血管造影术后使用股动脉压迫止血器患者早期活动的循证实践方案,规范临床应用并评价其效果,以提高患者舒适度。方法将最佳证据制定成临床实践的审查指标应用于脑血管造影术后患者,对照组和观察组各48例患者进行审查,观察比较对照组和观察组患者的舒适度、腰背部疼痛率及术后并发症发生情况。结果证据应用后观察组患者舒适度评分高于对照组,患者腰背部疼痛评分低于对照组,2组比较差异具有统计学意义(P<0.05);对照组和观察组的术后并发症发生率比较,差异无统计学意义(P>0.05)。结论基于证据制定的脑血管造影术后使用股动脉压迫止血器患者早期活动的循证实践方案可提高护士的循证能力,规范临床工作流程,有效提高患者舒适度,减轻了患者腰酸背痛。

心电向量图诊断高血压早期心脏靶器官损害的临床应用及影响因素

目的探讨心电向量图(vectorcardiogram,VCG)对高血压心脏电活动异常的诊断价值,并分析早期心脏靶器官损害的影响因素。方法选取昆明市中医医院心血管病科2022年1月至2023年2月的高血压病住院患者80例,经超声心动图(ultrasound cardiogram,UCG)排外心脏结构异常。比较心电图(electrocardiogram,ECG)与VCG对异常心室除极与复极指标的检出情况。按心电向量检查结果将80例病例分为正常组(n=40)与异常组(n=40),比较2组早期心脏损害的相关影响因素指标,将差异有统计学意义的因素做二元Logistic回归分析,筛选出早期心脏损害的独立影响因素。结果VCG检出异常心室复极指标较ECG有优势(P<0.05),二者对异常除极指标的检出差异无统计学意义(P>0.05)。正常组与异常组比较,在年龄、规律服药、家族史、糖尿病、24 h平均收缩压(24 h average systolic blood pressure,24 h SBP)、白昼平均收缩压(daytime average systolic blood pressure,DSBP)、夜间平均收缩压(night average systolic blood pressure,NSBP)、血压负荷值、清晨血压、脉压差等指标上,差异有统计学意义(P<0.05)。二元Logistic回归分析显示,年龄[OR(95%CI)=0.891,0.998]、夜间平均收缩压[OR(95%CI)=1.018,2.10]、家族史[OR(95%CI)=0.029,0.499]、糖尿病[OR(95%CI)=0.042,0.916]是高血压早期心脏损害的独立影响因素。结论VCG为高血压早期心脏靶器官损害的有效检测手段。

早期分阶段肺康复在肺叶切除术重症肺癌患者中的应用

目的分析早期分阶段肺康复方案对肺叶切除术重症肺癌患者肺功能、癌因性疲乏及身体活动量的影响。方法随机抽样选取2019年6月至2020年5月于新疆医科大学附属肿瘤医院行肺叶切除术的112例重症肺癌患者为研究对象。按照入组先后顺序将其分为对照组和观察组,每组56例,2组患者基线资料比较差异无统计学意义(P>0.05),具有可比性。对照组给予常规康复护理,观察组在对照组基础上添加早期分阶段肺康复方案干预,对2组患者进行为期18个月的随访研究,比较2组患者干预前或术前3 d以及干预后1、6、18个月肺功能指标[第1秒用力呼气容积(FEV1)、第1秒用力呼气容积/用力肺活量(FEV1/FVC)]、癌因性疲乏发生率、每日身体活动时间、焦虑自评量表(SAS)评分和抑郁自评量表(SDS)评分。结果观察组癌因性疲乏发生率(44.64%)低于对照组(64.29%),差异有统计学意义(P=0.037)。重复测量方差分析显示,FEV1、FEV1/FVC、每日身体活动时间、SAS评分、SDS评分主体内效应及主体间效应有统计学意义(P<0.05),FEV1、FEV1/FVC、每日身体活动时间、SAS评分、SDS评分随时间发生变化,且因组别不同而存在差异。干预后1、6、18个月,观察组FEV1、FEV1/FVC、每日身体活动时间高于对照组,SAS评分、SDS评分低于对照组,差异有统计学意义(P<0.05)。结论在常规康复护理基础上添加早期分阶段肺康复干预,能够改善肺叶切除术重症肺癌患者远期肺功能与负性情绪,降低癌因性疲乏发生率,提高身体活动量。

游戏管理模式对小儿心胸术后早期下床活动及呼吸功能恢复的影响

目的探讨游戏管理模式对小儿心胸术后早期下床活动及呼吸功能恢复的影响。方法选择2021年11月至2022年10月,收治的小儿心胸98例,按照护理干预方式不同分为对照组和观察组,每组49例。对照组给予常规护理,观察组给予游戏管理模式干预;对2组患儿术后恢复情况比较;观察2组患儿早期下床活动情况;比较2组患儿术后呼吸功能恢复情况,观察2组患儿依从性及家长满意度情况。结果观察组术后拆线时间、住院时间比对照组缩短,术后24 h疼痛评分低于对照组(P<0.05);观察组首次下床时间比对照组短,下床活动的时间及活动量高于对照组(P<0.05);观察组术后呼吸功能恢复优于对照组(P<0.05);观察组患儿依从性高于对照组,观察组家长满意度高于对照组(P<0.05)。结论对小儿心胸术后给予游戏管理模式干预,可以加快术后恢复,减轻术后疼痛,促进术后早期下床活动及呼吸功能的恢复,并可提高患儿护理依从性及家长对护理的满意度。

沙库巴曲缬沙坦治疗对早期急性失代偿心力衰竭患者血小板活化状态、炎症因子、心肌损伤因子的影响

目的研究沙库巴曲缬沙坦(SV)治疗早期急性失代偿心力衰竭(ADHF)及对血小板活化状态、炎症因子、心肌损伤因子的影响。方法前瞻性选择2020年1月至2022年12月于武汉市中医医院接受治疗的ADHF患者86例,依据随机数字表法将其分为SV组(n=43)、对照组(n=43)。对照组行常规治疗+培哚普利治疗,SV组行常规治疗+SV治疗。观察两组治疗后的临床疗效,比较两组治疗前、治疗3个月后的心功能指标[左心室射血分数(LVEF)、左室收缩末期内径(LVESD)及左室舒张末期内径(LVEDD)]、血清血小板活化状态指标[血小板溶酶体膜糖蛋白(CD63)、α-颗粒膜蛋白(CD62P)]、炎症因子[肿瘤坏死因子-α(TNF-α)、高敏C-反应蛋白(hs-CRP)、白细胞介素-33(IL-33)]水平、心肌损伤因子[微管链接蛋白(Nexilin)、可溶性凋亡相关因子配体(sFasL)、半乳糖凝集素3(Gal-3)]水平,观察两组治疗过程中的不良反应发生情况。结果SV组治疗的总有效率为83.72%,高于对照组(62.79%),差异有统计学意义(P<0.05)。治疗3个月后,SV组LVEF为(48.63±5.06)%,高于对照组[(43.97±4.61)%],LVESD、LVEDD及血清CD63、CD62P、TNF-α、hs-CRP、IL-33、Nexilin、sFasL、Gal-3水平分别为(46.76±4.93)mm、(52.49±5.46)mm、(4.87±0.52)%、(4.63±0.49)%、(14.87±1.69)pg/mL、(5.02±0.52)mg/L、(112.60±13.64)ng/L、(0.73±0.08)μg/L、(0.14±0.01)ng/L、(22.75±2.43)ng/L,均低于对照组[(51.53±5.36)mm、(57.40±5.96)mm、(6.21±0.64)%、(5.97±0.62)%、(18.95±2.02)pg/mL、(6.84±0.71)mg/L、(143.08±16.84)ng/L、(0.95±0.10)μg/L、(0.19±0.02)ng/L、(30.68±3.31)ng/L],差异均有统计学意义(P<0.05)。两组不良反应发生率比较差异无统计学意义(13.95%vs.11.63%)(P>0.05)。结论SV治疗可提高ADHF患者的临床疗效,抑制血小板活化,缓解炎症反应,避免心肌损伤,改善患者心功能,安全性高。

从“独鹤与飞”到“译事之光”——鲁迅早期文学活动中的“呐喊”

鲁迅早期文学活动大致分为两个阶段,即留学日本时期和回国后的“沉默十年”。一般认为鲁迅早期文学活动是在其加入五四文学革命的准备阶段,这一观点大致成立,但忽略了鲁迅早期文学活动的重要性。其实,此时鲁迅已经开始其后一直延续的文学道路,即一面介绍外国文学,一面从事新文学创作和学术研究,他早期的一些重要文章和文学活动完全可以视为后来发出“呐喊”的前奏,或者说就是其最初的“呐喊”。对此,应结合鲁迅与绍兴地域文化关系及其在京环境影响等重新审视。