Associations of preterm and early-term birth with suspected developmental coordination disorder:a national retrospective cohort study in children aged 3-10 years

Background This study analyzed the motor development and suspected developmental coordination disorder of very and moderately preterm(<34^(+0) gestational age),late preterm(34^(+0)-36^(+6)gestational week),and early-term(37^(+0)-38^(+6) gestational week)children compared to their full-term peers with a national population-based sample in China.Methods A total of 1673 children(799 girls,874 boys)aged 3-10 years old were individually assessed with the Movement Assessment Battery for Children-second edition(MABC-2).The association between gestational age and motor performance of children was analyzed using a multilevel regression model.Results The global motor performance[β=-5.111,95%confidence interval(CI)=-9.200 to-1.022;P=0.015]and bal-ance(β=-5.182,95%CI=-5.055 to-1.158;P=0.003)for very and moderately preterm children aged 3-6 years old were significantly lower than their full-term peers when adjusting for confounders.Late preterm and early-term children showed no difference.Moreover,very and moderately preterm children aged 3-6 years had a higher risk of suspected devel-opmental coordination disorder(DCD)(≤5 percentile of MABC-2 score)when adjusting for potential confounders[odds ratio(OR)=2.931,95%CI=1.067-8.054;P=0.038].Late preterm and early-term children showed no difference in motor performance from their full-term peers(each P>0.05).Conclusions Our findings have important implications for understanding motor impairment in children born at different gestational ages.Very and moderately preterm preschoolers have an increased risk of DCD,and long-term follow-up should be provided for early detection and intervention.

Short- and long-term outcomes of lung volume reduction surgery

In 1957, Brantigan applied lung volume reduction surgery （LVRS） to the treatment of emphysema. In 1995, Cooper reused this operation and obtained remarkable benefit in patients with chronic obstructive pulmonary disease （COPD）. Although there are still some doubts about the effect of LVRS, in the past 10 years, a lot of clinical information approved that LVRS can give benefit to more than 70% of COPD patients. At present, a series of researches in long-term investigation and function evaluation such as NETT have got elementary affirmative conclusion about some disputative problems.