旱莲草凝胶软糖的研制

以旱莲草浓缩汁、白砂糖和柠檬酸为主要原料,明胶,卡拉胶作为混合凝胶剂,制备具有旱莲草风味和保健功能的旱莲草软糖,通过研究旱莲草浓缩汁、凝胶剂、白砂糖和柠檬酸对旱莲草软糖品质的影响,获得最佳制备工艺与配方。

Biological and Functional Properties of Wedelolactone in Human Chronic Diseases

Medicinal herbs are well known and studied over the past millennia in most of the developing countries as a rational means of treatment against various diseases and disorders.Wedelolactone(WDL),a major bioactive compound in Eclipta prostrata L(Eclipta alba L),has been reported with potential benefits in human health against chronic diseases.However,a comprehensive study on WDL pharmacological benefits in various ailments,to the best of our knowledge,is not yet reported.Thereof,the present review provides the recent therapeutic applications in reference to biological and functional activities against major human chronic diseases,including cardiovascular,cancer,diabetes mellitus,liver disease,Alzheimer’s disease,and androgenetic alopecia.In this study,we collected all the relevant experimental information on WDL from Scientific databases such as PubMed,Web of Science,Science Direct,and Google Scholar.Conclusively,WDL is recognized as a key anti-oxidant with both specific regulator and inhibitor of major drug targetable proteins in human chronic diseases and disorders.Hence,WDL as a novel therapeutic bioactive molecule is advised to explore further for relevant pharmacological activities.

墨旱莲不同药用部位UPLC特征图谱及5种成分含量测定研究

目的建立墨旱莲超高效液相色谱(UPLC)特征图谱及咖啡酸、木犀草苷、异绿原酸B、4,5-O-二咖啡酰基奎宁酸、蟛蜞菊内酯的含量测定方法,对墨旱莲不同药用部位的质量进行评价。方法采用Agilent SBC_(18)色谱柱(100 mm×2.1 mm,1.8μm),以乙腈-0.53%磷酸溶液(含0.8%三乙胺)为流动相进行梯度洗脱,流速0.3 mL/min,检测波长330 nm。采用外标法测定11批墨旱莲药材及其花、叶、茎中5种成分的含量。采用SPSS20.0软件对数据进行聚类分析和主成分分析。结果建立了墨旱莲UPLC特征图谱共有模式,确定了9个共有峰,指认了5个色谱峰,并测定不同药用部位5种成分的含量。通过聚类分析和主成分分析可将11批样品分为三类,与特征图谱和含量测定结果基本相符,表明墨旱莲不同药用部位的质量存在差异。结论本研究建立的方法简便,结果稳定、准确,可为墨旱莲药材的质量控制提供依据。

旱莲草保健果冻的研制

探索制作旱莲草保健果冻的最佳配方。以旱莲草汁、卡拉胶、魔芋胶和黄原胶为主要原料设计出旱莲草果冻的试验方案和工艺流程,经过一系列的单因素和正交试验确定旱莲草保健果冻的最佳工艺配方。复合胶粉1.1%、白砂糖添加量18%、柠檬酸添加量0.14%、旱莲草汁30%和适量的山梨酸钾。采用该配方制备的果冻,营养价值高、淡淡的中草药味、光滑细腻、酸甜可口。