With the extensive use of the Internet and mobile technology, E-commerce in China has shown tremendous growth advantages and market potential, especially in promoting the access of eco-agriculture products. The E-comm...With the extensive use of the Internet and mobile technology, E-commerce in China has shown tremendous growth advantages and market potential, especially in promoting the access of eco-agriculture products. The E-commerce of agriculture products has shown diversification on the mainstay. "Three products, one indication"(pollution-free, green product, organic product, geographical indication) has becomes the primary character. Although the market of fresh products occupies a limited and meager profit, the blue sea effect has caused capital to enter into a large-scale development. It is very clearly shown after the analysis that the market of eco-agricultural E-commerce is vast and the expansionist policy for E-commerce environment is favorable. Meanwhile the required hardware and software of network in E-commerce are basically equipped with rapid development of service technology and strong driving force for innovation and development as well as an endless stream of new models and platforms. The whole phrase of development can be divided into five major stages. Through the analysis of five perspectives, such as platform, driver, participant, food supplier and Taobao, 16 types of agro-products E-commerce models and their different types of e-payment support systems are summarized, revealing the two major bottlenecks of development, namely the markets with limited share and low profit-making and the impact of cold chain services on E-commerce development. The thesis finally fortells the ten trends for the future development.展开更多
Fountain Set Limited announced that its branch brand'Fountain Set' was producing 2011 autumn-winter collections on the 2010 Intertextile Shanghai Apparel Fabrics Trade Fair,displaying new products
Concepts and connotations of circular economy and eco-agricultural tourism were introduced,and feasibility of applying circular economy in eco-agricultural tourism was further studied.It was stressed that development ...Concepts and connotations of circular economy and eco-agricultural tourism were introduced,and feasibility of applying circular economy in eco-agricultural tourism was further studied.It was stressed that development of eco-agricultural tourism complies with the theme of resource recycling,moreover,both eco-agricultural tourist products and circular economy value environment protection,and target at the win-win of ecological and economic benefits.From the perspective of circular economy,the construction of eco-agricultural tourist product mode was studied,construction of eco-agricultural tourist areas,catering and accommodation areas and traffic construction of eco-agricultural scenic areas were discussed.The study stressed that connotations of circular economy can be used to restrain eco-agricultural tourism,and realize recycling and sustainable development of resources.展开更多
Ammonia plays a crucial role in contemporary society,impacting medicine,agriculture,and the chemical industry.The conventional industrial synthesis of NH_(3) through the Haber-Bosch technique,carried out under severe ...Ammonia plays a crucial role in contemporary society,impacting medicine,agriculture,and the chemical industry.The conventional industrial synthesis of NH_(3) through the Haber-Bosch technique,carried out under severe reaction conditions,leads to substantial energy consumption and environmental pollution.It is thus imperative for NH_(3) synthesis methods to be investigated under more favorable conditions.Synthesis of ammonia by electrocatalysis can effectively reduce the environmental damage and other urgent problems,which is a promising solution.Metal-nitrogen series batteries(M-N batteries),such as metal-nitrogen gas batteries,metal-nitrogen oxide batteries and metal-oxynitride batteries have been regarded recently as an exemplar of concurrent NH_(3) synthesis and energy production.Nonetheless,the large-scale application of these batteries is still limited by numerous challenges are currently existing in building high-efficiency M-N batteries,including poor Faradic efficiency and low NH_(3) yield.Therefore,a comprehensive overview of M-N batteries is offered,specifically focusing on advanced strategies for designing highly efficient cathode catalysts in anticipation of future developments.The metal anodes,cathodic electro-reduction reactions,and design principles are encompassed in the discussion,offering detailed insights to enhance understanding.Mechanisms,feasibility analyses,technoeconomic assessments,device combinations,and comparative evaluations are delved into in the review,contributing to a thorough comprehension of diverse systems and their application potential.Perspectives and opportunities for future research directions are also delineated.展开更多
The Ecological-living-productive land(ELPL)classification system was proposed in an effort to steer China's land pattern to an ecological-centered path,with the development model shifting from a single function in...The Ecological-living-productive land(ELPL)classification system was proposed in an effort to steer China's land pattern to an ecological-centered path,with the development model shifting from a single function into more integrated multifunction land use.The focus is coordinating the man-land contradictions and developing an intensive,efficient and sustainable land use policy in an increasingly tense relationship between humans and nature.Driven by socioeconomic change and rapid population growth,many cities are undergoing urban sprawl,which involves the consumption of cropland and ecological land and threatens the ecological balance.This paper aims to quantitatively analyze the critical effects of ELPL changes on eco-environmental quality according to land use classification based on leading function of ecology,living and production from 1990 to 2015 with a case study of Xining City.Also,four future land use scenarios were simulated for 2030 using the Future Land Use Simulation(FLUS)model that couples human and natural effects.Our results show a decrease in productive land(PL)and an increase in ecological land(EL)and living land(LL)in Xining City.Forestry ecological land(FEL)covered the top largest proportion;agriculture productive land(APL)showed the greatest reduction and urban and rural living land(U-RLL)presented a dramatic increase.The eco-environmental quality improved in 1990-2010,mainly affected by the conversion of APL to FEL and GEL.However,the encroachment of U-RLL into APL,other ecological land(OEL)and FEL was the main contributor to the decline in eco-environmental quality in 2010-2015 as well as the primary reason for the increase area of lower-quality.The Harmonious Development(HD)-Scenario,characterized by a rational allocation of LL and PL and a better eco-environment,would have implications for planning and monitoring future management of ELPL,and may represent a valuable reference for local policy-makers.展开更多
BACKGROUND Advanced glycation end products(AGEs)are diabetic metabolic toxic products that cannot be ignored.Nε-(carboxymethyl)lysine(CML),a component of AGEs,could increase macrophage lipid uptake,promote foam cell ...BACKGROUND Advanced glycation end products(AGEs)are diabetic metabolic toxic products that cannot be ignored.Nε-(carboxymethyl)lysine(CML),a component of AGEs,could increase macrophage lipid uptake,promote foam cell formation,and thereby accelerate atherosclerosis.The receptor for AGEs(RAGE)and cluster of differentiation 36(CD36)were the receptors of CML.However,it is still unknown whether RAGE and CD36 play key roles in CML-promoted lipid uptake.AIM Our study aimed to explore the role of RAGE and CD36 in CML-induced macrophage lipid uptake.METHODS In this study,we examined the effect of CML on lipid uptake by Raw264.7 macrophages.After adding 10 mmol/L CML,the lipid accumulation in macrophages was confirmed by oil red O staining.Expression changes of CD36 and RAGE were detected with immunoblotting and quantitative real-time polymerase chain reaction.The interaction between CML with CD36 and RAGE was verified by immunoprecipitation.We synthesized a novel N-succinimidyl-4-18Ffluorobenzoate-CML radioactive probe.Radioactive receptor-ligand binding assays were performed to test the binding affinity between CML with CD36 and RAGE.The effects of blocking CD36 or RAGE on CML-promoting lipid uptake were also detected.RESULTS The study revealed that CML significantly promoted lipid uptake by macrophages.Immunoprecipitation and radioactive receptor-ligand binding assays indicated that CML could specifically bind to both CD36 and RAGE.CML had a higher affinity for CD36 than RAGE.ARG82,ASN71,and THR70 were the potential interacting amino acids that CD36 binds to CML Anti-CD36 and anti-RAGE could block the uptake of CML by macrophages.The lipid uptake promotion effect of CML was significantly attenuated after blocking CD36 or RAGE.CONCLUSION Our results suggest that the binding of CML with CD36 and RAGE promotes macrophage lipid uptake.展开更多
Objective: To evaluate the ovicidal, larvicidal and adulticidal potential of neem cake fractions of different polarity against the rural malaria vector Anopheles culicifacies(An.culicifacies).Methods: Neem cake fracti...Objective: To evaluate the ovicidal, larvicidal and adulticidal potential of neem cake fractions of different polarity against the rural malaria vector Anopheles culicifacies(An.culicifacies).Methods: Neem cake fractions' total methanol extract(NTMeOH), total ethyl acetate extract(NTAc OEt), ethyl acetate fraction after repartition with NTMe OH(NRAc OEt),butanol fraction after repartition with NTMeOH(NRBuOH), and aqueous fraction after repartition of NTMeOH(NRH2O) were tested against An. culicifacies eggs, fourth instar larvae and adults.Results: In larvicidal experiments, NTMeOH, NTAcOEt, NRAcOEt, NRBuOH and NRH2O achieved LC50 values of 1.32, 1.50, 1.81, 1.95 and 2.54 mg/L, respectively. All fractions tested at 150 mg/L were able to reduce egg hatchability of more than 50%, with the exception of NTAc OEt and NRAc OEt. In adulticidal assays, NTMeOH, NTAcOEt,NRAcOEt, NRBuOH and NRH2O achieved LC50 values of 3.01, 2.95, 3.23, 3.63 and3.00 mg/L, respectively.Conclusions: Overall, this study suggests that the methanolic fractions of neem cake may be considered as a new and cheap source of highly effective compounds against the rural malaria vector An. culicifacies.展开更多
Recently,both the importance and awareness relating to food safety relating to agrochemicals,chemical fertilizers,the pollution of ecosystem and unwholesome foods are growing rapidly.For the same reason,the purchaser&...Recently,both the importance and awareness relating to food safety relating to agrochemicals,chemical fertilizers,the pollution of ecosystem and unwholesome foods are growing rapidly.For the same reason,the purchaser's curiosity increases to know about the production process which can be accomplished by production traceability system.The traceability system can store and superintend the specific attribute information about products regarding the productive centre,producer and production finish data.The products undergo various circulation processes and they are being managed by individually constructed traceability system.Thus,it is difficult for the producer and the consumer to guarantee the safety from transpirable issues about the falsification of production traceability because the traceability information can be re-produced by forging through various ways.So in this paper,we proposed a system for integrated management of agro-fishery products based on quick response code(QR-code)for forgery prevention which may help to solve these issues.The proposed system makes QR-code using production information provided by producer.And then it is provided to the distributor and the consumer through integrated service model using the QR-code.Therefore,this system make sure to provide the same production traceability about the products to the distributor and the consumer and always keeps both updated with the same information.展开更多
Eco-city development is a healthy process towards sustainable development, within the carrying capacity of local ecosystem through changing production mode, consumption behavior and decision instrument based on ecolog...Eco-city development is a healthy process towards sustainable development, within the carrying capacity of local ecosystem through changing production mode, consumption behavior and decision instrument based on ecological economics and system engineering. The key to its planning is an ecological integration to make trade-off between economic wealth and environmental health, between material and spiritual civilization, between natural and human eco-cybernetics. Integration, demonstration, citizens’ participation and scientists’ and technician’s catalyzing are the key instruments for the implementation of the ecocity plan. "Clean production" and "ecological industry" are key elements in comprehensive development towards an eco-city. Beyond the technical and management questions, how to interlink production, consumption and reduction at the local and regional level, the spatial and urban dimension should be considered in order to perform an integrative urban eco-space.展开更多
"Internet +" eco-production and eco-tourism carried out by agricultural enterprises is one of ways to increase income.Urban economic development index evaluation value(u_1),agricultural enterprises' eco-..."Internet +" eco-production and eco-tourism carried out by agricultural enterprises is one of ways to increase income.Urban economic development index evaluation value(u_1),agricultural enterprises' eco-production and eco-tourism index evaluation value(u_2) and Internet popularity index evaluation value(u_3) constitute the ternary coupling system.The ternary coupling coordination degree(D_3) combined with u_2 can be used to judge whether the agricultural enterprises practise eco-production and eco-tourism mode.When u_2≥ 0.5000,D3≥0.6000,the autonomous mode for agricultural enterprises can be used; when 0.4000≤u_2< 0.5000,0.5000≤D_3< 0.6000,the mode of cooperation with travel agency can be used; when 0.3000 ≤u_2< 0.4000,0.4000 ≤D < 0.5000,the tourism business transfer mode can be used; when u_2< 0.3000,D < 0.4000,the tourism business should not be carried out.All the above four modes require "Internet +".展开更多
The production cycle of open-cast coal mines generally in eludes drilling, blasting, loading, hauling and coal preparation activities. Individual optimization of these activities does not mean that the whole system is...The production cycle of open-cast coal mines generally in eludes drilling, blasting, loading, hauling and coal preparation activities. Individual optimization of these activities does not mean that the whole system is optimized. This paper proposes a cost model considering all activities in mining cycle and system-wide approach to minimize the total mining cost of bench production. Since the fragmentation size and blast-hole diameter are linked to all activities of mining system, they are considered as decision variables in the problem form ul at io n. The operatio n costs are then minimized by using the evolutionary algorithm. Moreover, the impact of the change in the explosive price, and the hourly unit cost of equipment on total mining cost is quantified by sensitivity analysis. A case study is implemented to demonstrate the developed model.展开更多
Our previous study showed an association between advanced glycation end products (AGEs) and neural tube defects (NTDs). To understand the molecular mechanisms underlying the effect of AGEs on neural tube developme...Our previous study showed an association between advanced glycation end products (AGEs) and neural tube defects (NTDs). To understand the molecular mechanisms underlying the effect of AGEs on neural tube development, C57BL/6 female mice were fed for 4 weeks with com- mercial food containing 3% advanced glycation end product bovine serum albumin (AGE-BSA) or 3% bovine serum albumin (BSA) as a control. After mating mice, oxidative stress markers including malondialdehyde and H202 were measured at embryonic day 7.5 (E7.5) of ges- tation, and the level of intracellular reactive oxygen species (ROS) in embryonic cells was determined at E8.5. In addition to evaluating NTDs, an enzyme-linked immunosorbent assay was used to determine the effect of embryonic protein administration on the N-(carboxymethyl) lysine reactivity of acid and carboxyethyl lysine antibodies at E10.5. The results showed a remarkable increase in the incidence of NTDs at El0.5 in embryos of mice fed with AGE-BSA (no hyperglycemia) compared with control mice. Moreover, embryonic protein administration resulted in a noticeable increase in the reactivity of N-(carboxymethyl) lysine and N(ε)-(carboxyethyl) lysine antibodies. Malondialdehyde and H2O2 levels in embryonic cells were increased at E7.5, followed by increased intracellular ROS levels at E8.5. Vitamin E supplementation could partially recover these phenomena. Collectively, these results suggest that AGE-BSA could induce NTDs in the absence of hyperglycemia by an underlying mechanism that is at least partially associated with its capacity to increase embryonic oxidative stress levels.展开更多
On the foundation of analyzing the closed loop logistics chain of product with multi-lifecycle, the connotation of environmental value is set forth, recurring to such conceptions as supply chain and value chain. The p...On the foundation of analyzing the closed loop logistics chain of product with multi-lifecycle, the connotation of environmental value is set forth, recurring to such conceptions as supply chain and value chain. The plotting rules about disassembly tree are discussed in detail. The reachable matrix R of components’ disas- sembly is introduced into distinguishing if disassembly is needed, in combination with disassembly-deciding vector X. Furthermore, the arithmetic of disassembly cost is put forward. And the cost-benefits of components’ reusing, materials’ recycling, safety disposing are dissertated based on the activity-based costing. Then the 0-1 goal-programming model on product recovery processing is established, with components’ demotion calculated. In addition, taking the PC’s recovery processing for example, we put it into application.展开更多
The spatial and temporal distributions of new production vary largely in different sea areas. To understand the level of new production in the sea area studied better, an estimate of new production must be obtained in...The spatial and temporal distributions of new production vary largely in different sea areas. To understand the level of new production in the sea area studied better, an estimate of new production must be obtained in large spatial and temporal scales. The ~234Th/ ~238U disequilibrium is an effective method for the study of new production. Two sampling strategies, vertically integrated sampling ap proach based on trapezoidal integration principle and discrete layer sampling approach, were compared in the studies of the xiamen Bay and the northern South China Sea. The scavenging fluxes and removal fluxes of ~234Th and the residence times for dissolved and particulate ~234Th were calculated. The coinci dent results from two Sampling approach suggest that vertically integrated sampling approach is not only effective and reliable, but also significantly reduces the number and volume of samples. It allows us to study new production by ba ^(234)Th - ^(238)U disequilibria in large spatial scale.展开更多
Research situation of eco-design is analyzed, and then thoughts and methods of eco-design are discused. The eco-design includes packaging modularization, dematerialization, energy-saving and bio-simulation.
Based upon broad-band CCD observation data of comet Hale-Bopp obtained by a 60cm telescope at Xinglong Station of Beijing Astronomical Observatory during March-August, 1996, the photometric results of comet Hale-Bopp ...Based upon broad-band CCD observation data of comet Hale-Bopp obtained by a 60cm telescope at Xinglong Station of Beijing Astronomical Observatory during March-August, 1996, the photometric results of comet Hale-Bopp are reported. Using the photometric results, the dust production rate, radius and mass of nucleus of comet Hale-Bopp are estimated as follows: dM/dt~1.5×10 5 kgs -1, R n~35.5km, and M n~5.65×10 16kg.展开更多
The development and dissemination of sawah rice eco-technology in Nigeria and Ghana as prerequisites for the actualization of green revolution in West Africa were described. It showed that the neglect of the eco-techn...The development and dissemination of sawah rice eco-technology in Nigeria and Ghana as prerequisites for the actualization of green revolution in West Africa were described. It showed that the neglect of the eco-technology and the overemphasis of the biotechnology have rendered the ineffective transferability of the green revolution process from Asia to Africa. The sawah eco-technology increases yield up to 5 t/hm2 through bunding and the use of inlet and outlet connecting irrigation and drainage, which enhances effective water control and management, improves the efficiency of fertilizer, improves nitrogen fixation by soil microbes and algae, increases the use of wetlands, improves soil organic matter accumulation, suppresses weed growth, and enhances immune mechanism of rice through nutrient supply. The current experience has therefore established that the technology overcomes the constraints that have limited the realization of green revolution in West Africa.展开更多
The continuous developing features in the design of mechanical product and based on 3D entity model is aimed at, and the extension of the 4-dimensional model with the process of designing, the knowledge described mode...The continuous developing features in the design of mechanical product and based on 3D entity model is aimed at, and the extension of the 4-dimensional model with the process of designing, the knowledge described model on the level of semantic understanding and summarizing the designing process and the way of discovering knowledge from multi-information model are studied. On the basis of designing the broad sensed collaborative system, through discussion of the relationship between the implicit knowledge of the users and the designing knowledge as well as commanding all the designing links, taking advantage of the way of concluding and deducting in the concept of the designers, the synthetic knowledge unit formed in the dynamic process from the conception design t9 the last design is schemed out, and the knowledge discovered principle in the dynamic designing process of the mechanical products and the key technology in its implementation under the milieu of network is brought forward.展开更多
This study was conducted to investigate the in-vitro production technology of embryos from young Dorper sheep, so as to provide technical support for the utilization of ovarian follicles in young Dorper sheep. Tests w...This study was conducted to investigate the in-vitro production technology of embryos from young Dorper sheep, so as to provide technical support for the utilization of ovarian follicles in young Dorper sheep. Tests were conducted from the induction of Dorper sheep of 4 to 8 weeks old using follicle stimulating hormone(FSH) and pregnant horse serum(PMSG), collection of oocytes, in-vitro oocyte maturation-fertilization-zygote cultivation and 2-4-cell-stage fertilized ovum transfer. The results showed that 585 oocytes were collected from eight Dorper sheep at the age of 4 and 8 weeks, with an average of 73.13 oocytes/sheep. 346 of the 2-4-cell-stage fertilized eggs were obtained, whose cleavage rate was 59.15%. 77 in-vitro fertilized eggs at 2-4-cell stage were transplanted into 17 recipient sheep, seven of which were pregnant and gave birth to 13 "test-tube sheep" with a conception rate of 41.18%. It is indicated that the hormone induction technique, in-vitro oocyte maturation-fertilization-zygote cultivation technique and 2-4-cell-stage fertilized ovum transfer technique used in this study can serve as effective techniques for the in-vitro production of embryos from Dorper sheep of 4-8 weeks old.展开更多
文摘With the extensive use of the Internet and mobile technology, E-commerce in China has shown tremendous growth advantages and market potential, especially in promoting the access of eco-agriculture products. The E-commerce of agriculture products has shown diversification on the mainstay. "Three products, one indication"(pollution-free, green product, organic product, geographical indication) has becomes the primary character. Although the market of fresh products occupies a limited and meager profit, the blue sea effect has caused capital to enter into a large-scale development. It is very clearly shown after the analysis that the market of eco-agricultural E-commerce is vast and the expansionist policy for E-commerce environment is favorable. Meanwhile the required hardware and software of network in E-commerce are basically equipped with rapid development of service technology and strong driving force for innovation and development as well as an endless stream of new models and platforms. The whole phrase of development can be divided into five major stages. Through the analysis of five perspectives, such as platform, driver, participant, food supplier and Taobao, 16 types of agro-products E-commerce models and their different types of e-payment support systems are summarized, revealing the two major bottlenecks of development, namely the markets with limited share and low profit-making and the impact of cold chain services on E-commerce development. The thesis finally fortells the ten trends for the future development.
文摘Fountain Set Limited announced that its branch brand'Fountain Set' was producing 2011 autumn-winter collections on the 2010 Intertextile Shanghai Apparel Fabrics Trade Fair,displaying new products
基金Supported by Scientific Research Foundation of Shandong Jiaotong University(R200907)~~
文摘Concepts and connotations of circular economy and eco-agricultural tourism were introduced,and feasibility of applying circular economy in eco-agricultural tourism was further studied.It was stressed that development of eco-agricultural tourism complies with the theme of resource recycling,moreover,both eco-agricultural tourist products and circular economy value environment protection,and target at the win-win of ecological and economic benefits.From the perspective of circular economy,the construction of eco-agricultural tourist product mode was studied,construction of eco-agricultural tourist areas,catering and accommodation areas and traffic construction of eco-agricultural scenic areas were discussed.The study stressed that connotations of circular economy can be used to restrain eco-agricultural tourism,and realize recycling and sustainable development of resources.
基金National Natural Science Foundation of China (22179065)Tianjin Graduate Research and Innovation Project (2022BKY018)。
文摘Ammonia plays a crucial role in contemporary society,impacting medicine,agriculture,and the chemical industry.The conventional industrial synthesis of NH_(3) through the Haber-Bosch technique,carried out under severe reaction conditions,leads to substantial energy consumption and environmental pollution.It is thus imperative for NH_(3) synthesis methods to be investigated under more favorable conditions.Synthesis of ammonia by electrocatalysis can effectively reduce the environmental damage and other urgent problems,which is a promising solution.Metal-nitrogen series batteries(M-N batteries),such as metal-nitrogen gas batteries,metal-nitrogen oxide batteries and metal-oxynitride batteries have been regarded recently as an exemplar of concurrent NH_(3) synthesis and energy production.Nonetheless,the large-scale application of these batteries is still limited by numerous challenges are currently existing in building high-efficiency M-N batteries,including poor Faradic efficiency and low NH_(3) yield.Therefore,a comprehensive overview of M-N batteries is offered,specifically focusing on advanced strategies for designing highly efficient cathode catalysts in anticipation of future developments.The metal anodes,cathodic electro-reduction reactions,and design principles are encompassed in the discussion,offering detailed insights to enhance understanding.Mechanisms,feasibility analyses,technoeconomic assessments,device combinations,and comparative evaluations are delved into in the review,contributing to a thorough comprehension of diverse systems and their application potential.Perspectives and opportunities for future research directions are also delineated.
基金the support of the National Natural Science Foundation of China(No.41661038)Soft Science Research Project of Science and Technology Department of Qinghai province(No.2015-ZJ-602)
文摘The Ecological-living-productive land(ELPL)classification system was proposed in an effort to steer China's land pattern to an ecological-centered path,with the development model shifting from a single function into more integrated multifunction land use.The focus is coordinating the man-land contradictions and developing an intensive,efficient and sustainable land use policy in an increasingly tense relationship between humans and nature.Driven by socioeconomic change and rapid population growth,many cities are undergoing urban sprawl,which involves the consumption of cropland and ecological land and threatens the ecological balance.This paper aims to quantitatively analyze the critical effects of ELPL changes on eco-environmental quality according to land use classification based on leading function of ecology,living and production from 1990 to 2015 with a case study of Xining City.Also,four future land use scenarios were simulated for 2030 using the Future Land Use Simulation(FLUS)model that couples human and natural effects.Our results show a decrease in productive land(PL)and an increase in ecological land(EL)and living land(LL)in Xining City.Forestry ecological land(FEL)covered the top largest proportion;agriculture productive land(APL)showed the greatest reduction and urban and rural living land(U-RLL)presented a dramatic increase.The eco-environmental quality improved in 1990-2010,mainly affected by the conversion of APL to FEL and GEL.However,the encroachment of U-RLL into APL,other ecological land(OEL)and FEL was the main contributor to the decline in eco-environmental quality in 2010-2015 as well as the primary reason for the increase area of lower-quality.The Harmonious Development(HD)-Scenario,characterized by a rational allocation of LL and PL and a better eco-environment,would have implications for planning and monitoring future management of ELPL,and may represent a valuable reference for local policy-makers.
基金Supported by The National Natural Science Foundation of China,No.82070455Natural Science Foundation of Jiangsu Province,No.BK20201225Medical Innovation Team Project of Jiangsu Province,No.CXTDA2017010。
文摘BACKGROUND Advanced glycation end products(AGEs)are diabetic metabolic toxic products that cannot be ignored.Nε-(carboxymethyl)lysine(CML),a component of AGEs,could increase macrophage lipid uptake,promote foam cell formation,and thereby accelerate atherosclerosis.The receptor for AGEs(RAGE)and cluster of differentiation 36(CD36)were the receptors of CML.However,it is still unknown whether RAGE and CD36 play key roles in CML-promoted lipid uptake.AIM Our study aimed to explore the role of RAGE and CD36 in CML-induced macrophage lipid uptake.METHODS In this study,we examined the effect of CML on lipid uptake by Raw264.7 macrophages.After adding 10 mmol/L CML,the lipid accumulation in macrophages was confirmed by oil red O staining.Expression changes of CD36 and RAGE were detected with immunoblotting and quantitative real-time polymerase chain reaction.The interaction between CML with CD36 and RAGE was verified by immunoprecipitation.We synthesized a novel N-succinimidyl-4-18Ffluorobenzoate-CML radioactive probe.Radioactive receptor-ligand binding assays were performed to test the binding affinity between CML with CD36 and RAGE.The effects of blocking CD36 or RAGE on CML-promoting lipid uptake were also detected.RESULTS The study revealed that CML significantly promoted lipid uptake by macrophages.Immunoprecipitation and radioactive receptor-ligand binding assays indicated that CML could specifically bind to both CD36 and RAGE.CML had a higher affinity for CD36 than RAGE.ARG82,ASN71,and THR70 were the potential interacting amino acids that CD36 binds to CML Anti-CD36 and anti-RAGE could block the uptake of CML by macrophages.The lipid uptake promotion effect of CML was significantly attenuated after blocking CD36 or RAGE.CONCLUSION Our results suggest that the binding of CML with CD36 and RAGE promotes macrophage lipid uptake.
基金Supported by UGC-MRP,New Delhi,India[No.F.No.36-250/2008(SR)24/03/2009]King Saud University,Saudi Arabia,Vice Deanship of Research Chairs:Research Chairs
文摘Objective: To evaluate the ovicidal, larvicidal and adulticidal potential of neem cake fractions of different polarity against the rural malaria vector Anopheles culicifacies(An.culicifacies).Methods: Neem cake fractions' total methanol extract(NTMeOH), total ethyl acetate extract(NTAc OEt), ethyl acetate fraction after repartition with NTMe OH(NRAc OEt),butanol fraction after repartition with NTMeOH(NRBuOH), and aqueous fraction after repartition of NTMeOH(NRH2O) were tested against An. culicifacies eggs, fourth instar larvae and adults.Results: In larvicidal experiments, NTMeOH, NTAcOEt, NRAcOEt, NRBuOH and NRH2O achieved LC50 values of 1.32, 1.50, 1.81, 1.95 and 2.54 mg/L, respectively. All fractions tested at 150 mg/L were able to reduce egg hatchability of more than 50%, with the exception of NTAc OEt and NRAc OEt. In adulticidal assays, NTMeOH, NTAcOEt,NRAcOEt, NRBuOH and NRH2O achieved LC50 values of 3.01, 2.95, 3.23, 3.63 and3.00 mg/L, respectively.Conclusions: Overall, this study suggests that the methanolic fractions of neem cake may be considered as a new and cheap source of highly effective compounds against the rural malaria vector An. culicifacies.
基金The MSIP(Ministry of Science,ICT&Future Planning),Korea,under the ITRC(Information Technology Research Center)support program(NIPA-2013-H0301-13-2006)supervised by the NIPA(National IT Industry Promotion Agency)
文摘Recently,both the importance and awareness relating to food safety relating to agrochemicals,chemical fertilizers,the pollution of ecosystem and unwholesome foods are growing rapidly.For the same reason,the purchaser's curiosity increases to know about the production process which can be accomplished by production traceability system.The traceability system can store and superintend the specific attribute information about products regarding the productive centre,producer and production finish data.The products undergo various circulation processes and they are being managed by individually constructed traceability system.Thus,it is difficult for the producer and the consumer to guarantee the safety from transpirable issues about the falsification of production traceability because the traceability information can be re-produced by forging through various ways.So in this paper,we proposed a system for integrated management of agro-fishery products based on quick response code(QR-code)for forgery prevention which may help to solve these issues.The proposed system makes QR-code using production information provided by producer.And then it is provided to the distributor and the consumer through integrated service model using the QR-code.Therefore,this system make sure to provide the same production traceability about the products to the distributor and the consumer and always keeps both updated with the same information.
文摘Eco-city development is a healthy process towards sustainable development, within the carrying capacity of local ecosystem through changing production mode, consumption behavior and decision instrument based on ecological economics and system engineering. The key to its planning is an ecological integration to make trade-off between economic wealth and environmental health, between material and spiritual civilization, between natural and human eco-cybernetics. Integration, demonstration, citizens’ participation and scientists’ and technician’s catalyzing are the key instruments for the implementation of the ecocity plan. "Clean production" and "ecological industry" are key elements in comprehensive development towards an eco-city. Beyond the technical and management questions, how to interlink production, consumption and reduction at the local and regional level, the spatial and urban dimension should be considered in order to perform an integrative urban eco-space.
基金Supported by Research Project of China Logistics Association,China Federation of Logistics and Purchasing-Industrial Upgrading-oriented Fuzzy Comprehensive Evaluation of Changsha Logistics Enterprises(2016CSLKT3-081)
文摘"Internet +" eco-production and eco-tourism carried out by agricultural enterprises is one of ways to increase income.Urban economic development index evaluation value(u_1),agricultural enterprises' eco-production and eco-tourism index evaluation value(u_2) and Internet popularity index evaluation value(u_3) constitute the ternary coupling system.The ternary coupling coordination degree(D_3) combined with u_2 can be used to judge whether the agricultural enterprises practise eco-production and eco-tourism mode.When u_2≥ 0.5000,D3≥0.6000,the autonomous mode for agricultural enterprises can be used; when 0.4000≤u_2< 0.5000,0.5000≤D_3< 0.6000,the mode of cooperation with travel agency can be used; when 0.3000 ≤u_2< 0.4000,0.4000 ≤D < 0.5000,the tourism business transfer mode can be used; when u_2< 0.3000,D < 0.4000,the tourism business should not be carried out.All the above four modes require "Internet +".
文摘The production cycle of open-cast coal mines generally in eludes drilling, blasting, loading, hauling and coal preparation activities. Individual optimization of these activities does not mean that the whole system is optimized. This paper proposes a cost model considering all activities in mining cycle and system-wide approach to minimize the total mining cost of bench production. Since the fragmentation size and blast-hole diameter are linked to all activities of mining system, they are considered as decision variables in the problem form ul at io n. The operatio n costs are then minimized by using the evolutionary algorithm. Moreover, the impact of the change in the explosive price, and the hourly unit cost of equipment on total mining cost is quantified by sensitivity analysis. A case study is implemented to demonstrate the developed model.
基金supported by the grant from Shaanxi Technology Committee of China,No.2013JM4001the China Scholarship Council(CSC)
文摘Our previous study showed an association between advanced glycation end products (AGEs) and neural tube defects (NTDs). To understand the molecular mechanisms underlying the effect of AGEs on neural tube development, C57BL/6 female mice were fed for 4 weeks with com- mercial food containing 3% advanced glycation end product bovine serum albumin (AGE-BSA) or 3% bovine serum albumin (BSA) as a control. After mating mice, oxidative stress markers including malondialdehyde and H202 were measured at embryonic day 7.5 (E7.5) of ges- tation, and the level of intracellular reactive oxygen species (ROS) in embryonic cells was determined at E8.5. In addition to evaluating NTDs, an enzyme-linked immunosorbent assay was used to determine the effect of embryonic protein administration on the N-(carboxymethyl) lysine reactivity of acid and carboxyethyl lysine antibodies at E10.5. The results showed a remarkable increase in the incidence of NTDs at El0.5 in embryos of mice fed with AGE-BSA (no hyperglycemia) compared with control mice. Moreover, embryonic protein administration resulted in a noticeable increase in the reactivity of N-(carboxymethyl) lysine and N(ε)-(carboxyethyl) lysine antibodies. Malondialdehyde and H2O2 levels in embryonic cells were increased at E7.5, followed by increased intracellular ROS levels at E8.5. Vitamin E supplementation could partially recover these phenomena. Collectively, these results suggest that AGE-BSA could induce NTDs in the absence of hyperglycemia by an underlying mechanism that is at least partially associated with its capacity to increase embryonic oxidative stress levels.
基金Supported by the National Natural Science Foundation of China(No.70472080)and Shanghai Shuguang Planning Program(No.70472080).
文摘On the foundation of analyzing the closed loop logistics chain of product with multi-lifecycle, the connotation of environmental value is set forth, recurring to such conceptions as supply chain and value chain. The plotting rules about disassembly tree are discussed in detail. The reachable matrix R of components’ disas- sembly is introduced into distinguishing if disassembly is needed, in combination with disassembly-deciding vector X. Furthermore, the arithmetic of disassembly cost is put forward. And the cost-benefits of components’ reusing, materials’ recycling, safety disposing are dissertated based on the activity-based costing. Then the 0-1 goal-programming model on product recovery processing is established, with components’ demotion calculated. In addition, taking the PC’s recovery processing for example, we put it into application.
基金National Natural Science Foundation of China! 49676296National Scientific and Technical Project! 97-926-04-02.
文摘The spatial and temporal distributions of new production vary largely in different sea areas. To understand the level of new production in the sea area studied better, an estimate of new production must be obtained in large spatial and temporal scales. The ~234Th/ ~238U disequilibrium is an effective method for the study of new production. Two sampling strategies, vertically integrated sampling ap proach based on trapezoidal integration principle and discrete layer sampling approach, were compared in the studies of the xiamen Bay and the northern South China Sea. The scavenging fluxes and removal fluxes of ~234Th and the residence times for dissolved and particulate ~234Th were calculated. The coinci dent results from two Sampling approach suggest that vertically integrated sampling approach is not only effective and reliable, but also significantly reduces the number and volume of samples. It allows us to study new production by ba ^(234)Th - ^(238)U disequilibria in large spatial scale.
基金Supported by Jiangsu Province Scientific Innovation Research of College Graduate
文摘Research situation of eco-design is analyzed, and then thoughts and methods of eco-design are discused. The eco-design includes packaging modularization, dematerialization, energy-saving and bio-simulation.
文摘Based upon broad-band CCD observation data of comet Hale-Bopp obtained by a 60cm telescope at Xinglong Station of Beijing Astronomical Observatory during March-August, 1996, the photometric results of comet Hale-Bopp are reported. Using the photometric results, the dust production rate, radius and mass of nucleus of comet Hale-Bopp are estimated as follows: dM/dt~1.5×10 5 kgs -1, R n~35.5km, and M n~5.65×10 16kg.
文摘The development and dissemination of sawah rice eco-technology in Nigeria and Ghana as prerequisites for the actualization of green revolution in West Africa were described. It showed that the neglect of the eco-technology and the overemphasis of the biotechnology have rendered the ineffective transferability of the green revolution process from Asia to Africa. The sawah eco-technology increases yield up to 5 t/hm2 through bunding and the use of inlet and outlet connecting irrigation and drainage, which enhances effective water control and management, improves the efficiency of fertilizer, improves nitrogen fixation by soil microbes and algae, increases the use of wetlands, improves soil organic matter accumulation, suppresses weed growth, and enhances immune mechanism of rice through nutrient supply. The current experience has therefore established that the technology overcomes the constraints that have limited the realization of green revolution in West Africa.
基金Selected from Proceedings of the 7th International Conference on Frontiers of DesignManufacturing(ICFDM'2006)This project is supported by National Natural Science Foundation of China(No.50275100)Key Scientific Technological Projects in Sichuan China(No.2006Z01-001-6).
文摘The continuous developing features in the design of mechanical product and based on 3D entity model is aimed at, and the extension of the 4-dimensional model with the process of designing, the knowledge described model on the level of semantic understanding and summarizing the designing process and the way of discovering knowledge from multi-information model are studied. On the basis of designing the broad sensed collaborative system, through discussion of the relationship between the implicit knowledge of the users and the designing knowledge as well as commanding all the designing links, taking advantage of the way of concluding and deducting in the concept of the designers, the synthetic knowledge unit formed in the dynamic process from the conception design t9 the last design is schemed out, and the knowledge discovered principle in the dynamic designing process of the mechanical products and the key technology in its implementation under the milieu of network is brought forward.
基金Supported by Earmarked Fund for Construction of National Wool Sheep Industry Technology Research System(CARS-39-24)Program for Science and Technology Development of Shanxi Province(20120311024-1)+1 种基金Fund for Science and Technology Innovation Team in Shanxi Province(201705D131028-20)Shanxi Agricultural Industry Development Technology Leading Fund(2017CYYL-08)
文摘This study was conducted to investigate the in-vitro production technology of embryos from young Dorper sheep, so as to provide technical support for the utilization of ovarian follicles in young Dorper sheep. Tests were conducted from the induction of Dorper sheep of 4 to 8 weeks old using follicle stimulating hormone(FSH) and pregnant horse serum(PMSG), collection of oocytes, in-vitro oocyte maturation-fertilization-zygote cultivation and 2-4-cell-stage fertilized ovum transfer. The results showed that 585 oocytes were collected from eight Dorper sheep at the age of 4 and 8 weeks, with an average of 73.13 oocytes/sheep. 346 of the 2-4-cell-stage fertilized eggs were obtained, whose cleavage rate was 59.15%. 77 in-vitro fertilized eggs at 2-4-cell stage were transplanted into 17 recipient sheep, seven of which were pregnant and gave birth to 13 "test-tube sheep" with a conception rate of 41.18%. It is indicated that the hormone induction technique, in-vitro oocyte maturation-fertilization-zygote cultivation technique and 2-4-cell-stage fertilized ovum transfer technique used in this study can serve as effective techniques for the in-vitro production of embryos from Dorper sheep of 4-8 weeks old.