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The Defects and Future Research Direction of the Auditof the Policy Implementation Effect 2 China 被引量:3
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作者 刘利 《石家庄经济学院学报》 2016年第3期97-99,共3页
近年来,政策执行效果审计在中国逐渐引起了关注.论文首先介绍了政策执行效果审计的内涵和研究的意义,在此基础上简要阐述了政策执行效果审计的发展现状,并指出了其缺陷,最后提出了未来的研究应重点关注建立政策执行效果审计理论框架体... 近年来,政策执行效果审计在中国逐渐引起了关注.论文首先介绍了政策执行效果审计的内涵和研究的意义,在此基础上简要阐述了政策执行效果审计的发展现状,并指出了其缺陷,最后提出了未来的研究应重点关注建立政策执行效果审计理论框架体系、完善政策执行效果审计评价指标体系、探索对政策本身的评价以及将政策执行效果审计与新兴互联网工程及信息技术结合起来等几个方面. 展开更多
关键词 政策执行效果审计 缺陷 研究方向
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EXPERIMENTAL RESEARCH ON THE ANTI-CANCER IMMUNOMODULA-TIVE EFFECT OF THE POLYSOCOHARIBE-PEPTIDE OF CORIOLUS VERSICOLOR 被引量:1
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作者 许良中 杨庆尧 +4 位作者 周金煦 陈瑞婷 李晓玉 胡玉娟 王筠默 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 1989年第2期10-15,共6页
Polysocoharibe-peptide of Coriolus Versicolor (PSP) is a new anti-cancer immunomodulative drug. The present paper reports on the experimental research done with this drug. It was found that PSP had the ability to reco... Polysocoharibe-peptide of Coriolus Versicolor (PSP) is a new anti-cancer immunomodulative drug. The present paper reports on the experimental research done with this drug. It was found that PSP had the ability to recover hemolysin HC50, to increase the weight of the thymus, and increase the alexin of serum C3 and the IgG content of tumor bearing mice. FSP also significantly raised the pha-gocytic activity of macrophages in normal mice. PSP had a significant inhibitory effect on P38S and S180 cells. At the concentration of 1 mg/ml, PSP inhibited the proliferating activity of some human tumor call lines, such as SGC 7901, SPC, SLY and Mei. It had a direct toxic effect on SPC cells. PSP significantly inhibited the synthesis of nucleic acids of Ehrlich ascites carcinoma cells. In addition, PSP was antagonistic to the side effects of chemotherapy and radiotherapy. 展开更多
关键词 PSP EXPERIMENTAL research ON THE ANTI-CANCER IMMUNOMODULA-TIVE effect OF THE POLYSOCOHARIBE-PEPTIDE OF CORIOLUS VERSICOLOR SPC
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The US Payor Landscape: Results from a Survey of Medical Directors and Pharmacy Directors on Comparative-Effectiveness Research
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作者 Richard A. Brook Jeff A. Carlisle +1 位作者 Stanton R. Mehr James E. Smeeding 《Journal of Pharmacy and Pharmacology》 2014年第7期432-438,共7页
关键词 药剂学 药理学 药学 药物分析 药典
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Empirical Research of Farmer College Students' Learning Ability and Learning Effect in the Digital Environment
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作者 Jixian ZHANG 《Asian Agricultural Research》 2013年第8期108-113,118,共7页
In the course of training farmer college students,there have been a number of problems facing the modern distance education based on digital learning environment,such as weak learning adaptability and ability of farme... In the course of training farmer college students,there have been a number of problems facing the modern distance education based on digital learning environment,such as weak learning adaptability and ability of farmers and diverse learning needs.Using the empirical methods of questionnaire survey and interview,this article conducts an analysis of the farmer college students' digital learning ability and learning effect,and based on the theoretical study and practical achievements,explores some aspects,such as the information literacy and entrepreneurship ability training for farmer college students,the reform of course teaching and practice teaching,and the building of digital learning platform and special resources.And finally some innovative ideas and recommendations are put forth. 展开更多
关键词 LEARNING needs DIGITAL LEARNING ENVIRONMENT Learni
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Research of the Effect of the Shear Stress on Endothelial Cells
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作者 Xu HOU Chang-Xiu WAN Hua HUANG(Dept. of Biomedical Engineering,Sichuan University, Chengdu 610065,China) 《生物医学工程学杂志》 EI CAS CSCD 北大核心 2005年第S1期65-66,共2页
关键词 research of the effect of the Shear Stress on Endothelial Cells
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Confounding Effect in Clinical Research of Otolaryngology and Its Control
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作者 Yong-qiang Yu Dong-yan Huang +7 位作者 Susan Armijo Olivo Huai-an Yang Yagesh Bambanini Lyn Sonnenberg Brenda Clark Gabriela Constantinescu Jason Qian Yu Ming Zhang 《Chinese Medical Sciences Journal》 CAS CSCD 2015年第2期121-130,共10页
Confounding effect is a critical issue in clinical research of otolaryngology because it can distort the research's conclusion. In this review, we introduce the definition of confounding effect, the methods of ver... Confounding effect is a critical issue in clinical research of otolaryngology because it can distort the research's conclusion. In this review, we introduce the definition of confounding effect, the methods of verifying and controlling the effect. Confounding effect can be prevented by research's design, and adjusted by data analysis. Clinicians would be aware and cautious about confounding effect in their research. They would be able to set up a research's design in which appropriate methods have been applied to prevent this effect.They would know how to adjust confounding effect after data collection. It is important to remember that sometimes it is impossible to eliminate confounding effect completely, and statistical method is not a master key. Solid research knowledge and critical thinking of our brain are the most important in controlling confounding effect. 展开更多
关键词 CLINICAL research OTOLARYNGOLOGY CONFOUNDING effect
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Researches on End Effects of Permanent Magnet Electromagnetic Launchers
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作者 MA Li-jun LIU Xiao-li LI Xiao-peng 《科技信息》 2013年第13期226-228,共3页
Brushless DC linear motors have considerable advantages of simpler structure,higher efficiency,higher thrust density and so on.They are well suited for many domains such as electromagnetic launch and launch-assist,but... Brushless DC linear motors have considerable advantages of simpler structure,higher efficiency,higher thrust density and so on.They are well suited for many domains such as electromagnetic launch and launch-assist,but it is inevitable that there exist longitudinal end effects in the mover of the motor caused by longitudinal discontinuities.The serious trouble caused by longitudinal end effects is the thrust ripple.Firstly,by using the method of finite element simulation,this paper studies the distribution of magnetic field and energy in the end region when the mover is in different positions in the range of a polar pitch and discusses the effective methods of reducing the longitudinal end effects.Then the law of the influence of different mover length on the longitudinal end effects has been studied by using analytic methods,and the influences of the mover length and its end geometry shape on the longitudinal end effects have been verified for the test model by using the method of finite element simulation. 展开更多
关键词 体育教育 体育精神 教学方法 体育教师 学生
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Henan Cultural Information Resources Sharing Project Persistent Effect Mechanism Research
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作者 Weigong CUI Hui JIAN +2 位作者 Yuan GAN Zhen ZHANG Yanfeng LIU 《Intelligent Information Management》 2009年第1期18-23,共6页
In order to reduce east--west section area of “digital divider” in China, Ministry of Culture laun- ches the National Cultural Information Resources Sharing Project in the mid-west provinces, and the state finance g... In order to reduce east--west section area of “digital divider” in China, Ministry of Culture laun- ches the National Cultural Information Resources Sharing Project in the mid-west provinces, and the state finance gives certain funds subsidy in the project construction period. Embarks highly from strategy during construction plan chosen and operational system management, as while as union digital library to construct a persistent effect mechanism. With the principle of state guidance, enterprise operation and benefit farmers, expand culture industry within the provincial and safeguard Cultural Information Resources Sharing Project sustainable development's, then promotes the rural economy culture full scale development. 展开更多
关键词 CULTURAL information resources SHARING project PERSISTENT effect mechanism research IPTV digital LIBRARY CULTURAL industry
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The Assessment of Non-Linear Effects in Clinical Research
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作者 Ton J. Cleophas Aeilko H. Zwinderman 《Pharmacology & Pharmacy》 2012年第2期139-147,共9页
Background: Novel models for the assessment of non-linear data are being developed for the benefit of making better predictions from the data. Objective: To review traditional and modern models. Results, and Conclusio... Background: Novel models for the assessment of non-linear data are being developed for the benefit of making better predictions from the data. Objective: To review traditional and modern models. Results, and Conclusions: 1) Logit and probit transformations are often successfully used to mimic a linear model. Logistic regression, Cox regression, Poisson regression, and Markow modeling are examples of logit transformation;2) Either the x- or y-axis or both of them can be logarithmically transformed. Also Box Cox transformation equations and ACE (alternating conditional expectations) or AVAS (additive and variance stabilization for regression) packages are simple empirical methods often successful for linearly remodeling of non-linear data;3) Data that are sinusoidal, can, generally, be successfully modeled using polynomial regression or Fourier analysis;4) For exponential patterns like plasma concentration time relationships exponential modeling with or without Laplace transformations is a possibility. Spline and Loess are computationally intensive modern methods, suitable for smoothing data patterns, if the data plot leaves you with no idea of the relationship between the y- and x-values. There are no statistical tests to assess the goodness of fit of these methods, but it is always better than that of traditional models. 展开更多
关键词 Non-Linear effects Clinical research Logit/Probit TRANSFORMATION Box Cox TRANSFORMATION ACE/AVAS Packages Curvilinear Data SPLINE MODELING Loess MODELING
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Research on Replacing Effects & Examination System of TBT against Tariff Impediment to Textile and Apparel Trade
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作者 Chengjianbing1 Lvjianming2 Chengpeng Jiang3 1.Yiwu Bureau of Exit and Entry Inspection and Quarantine 2.Zhejiang Chinese Medical University 3. C.M.U. 《China Textile》 2010年第10期48-55,共8页
With the cutoff and limitation of tariff and traditional non-tariff Barriers to Trade by GATT/WTO, Technical Barriers to Trade (TBT) has gradually replaced tariff and general non-tariff Barriers to Trade and become an... With the cutoff and limitation of tariff and traditional non-tariff Barriers to Trade by GATT/WTO, Technical Barriers to Trade (TBT) has gradually replaced tariff and general non-tariff Barriers to Trade and become an important measurement in new trade protectionism. This article analyzes the replacement of TBT on tariff barrier for exporting countries, as well as the trading pattern of TBT in its maturing period through the discussion of macro strategies of surpassing TBT; meanwhile it also probes into the examination and supervision policies of governmental functional departments. 展开更多
关键词 TBT WTO GATT research on Replacing effects Examination System of TBT against Tariff Impediment to Textile and Apparel Trade
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Comparative effectiveness research and health care reform in C hina
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作者 Yilong Wang Yongjun Wang 《Journal of Translational Neuroscience》 2016年第1期24-26,共3页
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Research on the effects of PIAS3 expression on the invasion of glioma TJ905 cells
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作者 潘天鸿 《外科研究与新技术》 2011年第3期204-205,共2页
Objective To investigate the function and possible mechanisms of PIAS3 expression on the invasion of TJ905 cells. Methods PIAS3 overexpression vectors were constructed and PIAS3 siRNA were chemically synthesized, whic... Objective To investigate the function and possible mechanisms of PIAS3 expression on the invasion of TJ905 cells. Methods PIAS3 overexpression vectors were constructed and PIAS3 siRNA were chemically synthesized, which were separately transfected into TJ905 cells for upregulation or 展开更多
关键词 PIAS research on the effects of PIAS3 expression on the invasion of glioma TJ905 cells
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基于倾向性评分匹配的T_(4a)期胃癌腔镜辅助与开腹手术近期疗效的对比分析
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作者 马鹏 贺爱军 +1 位作者 曹波 李小宝 《腹腔镜外科杂志》 2024年第2期91-97,共7页
目的:探讨T_(4a)期胃癌行腹腔镜辅助D2根治术的近期疗效。方法:采用倾向性评分匹配,分析2014年1月至2020年12月为T_(4a)期胃腺癌患者行D2淋巴结清扫的临床资料。将患者分为开腹组(n=362)与腹腔镜组(n=134),通过倾向性评分匹配对数据进行... 目的:探讨T_(4a)期胃癌行腹腔镜辅助D2根治术的近期疗效。方法:采用倾向性评分匹配,分析2014年1月至2020年12月为T_(4a)期胃腺癌患者行D2淋巴结清扫的临床资料。将患者分为开腹组(n=362)与腹腔镜组(n=134),通过倾向性评分匹配对数据进行1∶1匹配,匹配容差设为0.03。最终获得两组病例各134例。比较两组手术情况、术后并发症、术后炎性指标变化及2年总生存率。结果:倾向性匹配后,两组基线资料具有可比性(P>0.05)。两组术后首次进食时间、住院时间、并发症情况差异均无统计学意义(P>0.05);腹腔镜组与开腹组手术时间[240(203.75,256.25)min vs.140(120,190)min,P<0.05]、术中出血量[200(100,300)mL vs.200(200,300)mL,P<0.05]、淋巴结清扫数量[20.5(17,27.25)vs.16(10,23),P<0.05]、切口长度[5(5,6)cm vs.12(10,15)cm,P<0.05]、术后排气时间[4(3,6)d vs.5(3,6)d,P<0.05]、术后下床活动时间[2(2,3)d vs.3(2,3)d,P<0.05]差异均有统计学意义。两组术前中性粒细胞-淋巴细胞比值、血小板-淋巴细胞比值、淋巴细胞-单核细胞比值差异无统计学意义(P>0.05),术后血小板-淋巴细胞比值差异无统计学意义,腹腔镜组中性粒细胞-淋巴细胞比值低于开腹组,淋巴细胞-单核细胞比值高于开腹组,差异有统计学意义。开腹组与腹腔镜组术后2年总生存率为53.3%与48.3%,差异无统计学意义(P=0.211)。结论:对于T_(4a)期胃癌,腹腔镜手术后并发症发生率、2年生存率与开腹手术相当,但腹腔镜手术具有创伤小、美观、术后康复快的优势。 展开更多
关键词 胃肿瘤 T_(4a)期 腹腔镜检查 剖腹术 疗效比较研究
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四物汤的药理作用研究进展
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作者 周大果 沈子芯 +1 位作者 牟春燕 朱路文 《中医药信息》 2024年第5期69-75,共7页
四物汤是补血调血的基础方,具有补血不滞血、行血不伤血的特点,常用于治疗临床多种疾病,具有较高的临床价值。笔者通过综述相关研究文献发现,四物汤具有补充血容量、活血抗凝、雌激素样作用、子宫双向调节、改善卵巢功能、降血脂、提高... 四物汤是补血调血的基础方,具有补血不滞血、行血不伤血的特点,常用于治疗临床多种疾病,具有较高的临床价值。笔者通过综述相关研究文献发现,四物汤具有补充血容量、活血抗凝、雌激素样作用、子宫双向调节、改善卵巢功能、降血脂、提高学习记忆能力、抗氧化损伤、抗炎抗菌、提高免疫功能、抗衰老、保肝和抗辐射、药物损伤及抗突变等药理作用,主要作用在血液系统、女性生殖系统与心脑血管系统,主要通过磷脂酰肌醇-3-激酶/蛋白激酶B(PI3K/Akt)信号通路、表皮生长因子受体/磷脂酰肌醇3-激酶(EGFR/PI3K)信号通路、肝激酶B1/腺苷酸活化蛋白激酶(LKB1/AMPK)信号通路等发挥治疗作用。 展开更多
关键词 四物汤 药理作用 研究进展
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三七药对的研究进展
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作者 王雪梅 李喜香 +1 位作者 宋薇 杨萍 《中华中医药学刊》 CAS 北大核心 2024年第5期206-210,共5页
三七作为临床常用中药,在临床应用中有多种药对形式。围绕近年来基于网络药理学的三七药对、传统三七药对及三七药对配伍前后化学成分变化的实验研究进行归纳和总结,系统阐释三七药对在临床应用的作用机制和科学内涵,为进一步研究三七... 三七作为临床常用中药,在临床应用中有多种药对形式。围绕近年来基于网络药理学的三七药对、传统三七药对及三七药对配伍前后化学成分变化的实验研究进行归纳和总结,系统阐释三七药对在临床应用的作用机制和科学内涵,为进一步研究三七药对使用规律、配伍理论、临床应用等方面提供新的思路。 展开更多
关键词 三七 药对 网络药理学 药理作用 化学成分 研究进展
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数字普惠金融影响我国共同富裕的效应研究
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作者 金月华 王梦晨 郭泱君 《杭州电子科技大学学报(社会科学版)》 2024年第1期31-40,共10页
文章基于2011—2021年省级面板数据,利用双向固定效应模型和门槛效应模型研究数字普惠金融影响我国共同富裕的效应。结果表明:数字普惠金融水平的提高对实现我国共同富裕有正影响效应,且这种影响效应存在明显的区域异质性,数字普惠金融... 文章基于2011—2021年省级面板数据,利用双向固定效应模型和门槛效应模型研究数字普惠金融影响我国共同富裕的效应。结果表明:数字普惠金融水平的提高对实现我国共同富裕有正影响效应,且这种影响效应存在明显的区域异质性,数字普惠金融对西部地区共同富裕的促进作用大于东部地区。数字金融覆盖广度、数字金融使用深度与共同富裕存在正相关关系,且在对应门槛变量达到一定值后,对共同富裕的促进作用显著增强;而普惠金融数字化程度与共同富裕呈负相关,但是当普惠金融数字化达到一定程度后,其将对共同富裕产生显著的正向影响。 展开更多
关键词 数字普惠金融 共同富裕 门槛效应 实证研究
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中央苏区农业科技的研究与推广
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作者 庞振宇 《农业考古》 北大核心 2024年第1期54-62,共9页
发展农业生产不仅需要开展土地革命来激发苏区群众的积极性,还需要以农业科技的研究与推广来提高农业生产力水平。在中央苏区,中国共产党和苏维埃政府创办农事试验场、农业学校和农产品展览所,研究农业科学技术,在选育优良品种、改良土... 发展农业生产不仅需要开展土地革命来激发苏区群众的积极性,还需要以农业科技的研究与推广来提高农业生产力水平。在中央苏区,中国共产党和苏维埃政府创办农事试验场、农业学校和农产品展览所,研究农业科学技术,在选育优良品种、改良土壤、防治病虫害、兴修水利、改良农具、植树造林等方面积极推广新技术和新经验,取得了很好的成效。农业科技的研究与推广,在解决中央苏区粮食安全等方面发挥了重要作用,这是中国共产党领导农业科技事业的开端。 展开更多
关键词 苏区 农业科技 研究机构 成效
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企业基础研究决策的同群效应及影响因素
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作者 朱相宇 关秉裕 郭之珍 《科技管理研究》 2024年第5期82-95,共14页
以2013-2022年中国沪深A股制造业和信息技术业上市企业为样本,实证检验基础研究的同群效应的存在性、模仿路径及其影响因素。研究发现,企业基础研究决策受行业内其他企业的影响,即存在行业同群效应,其模仿路径呈现出一定的先内后外规律... 以2013-2022年中国沪深A股制造业和信息技术业上市企业为样本,实证检验基础研究的同群效应的存在性、模仿路径及其影响因素。研究发现,企业基础研究决策受行业内其他企业的影响,即存在行业同群效应,其模仿路径呈现出一定的先内后外规律。企业所处的竞争地位越高,既往基础研究经验越丰富,其基础研究决策越容易受到行业同群的影响。相较于非国有企业,国有企业基础研究决策受同群企业影响程度较高。研究进一步发现,企业基础研究决策同群效应对企业创新绩效有正向促进作用。研究发现为更好地理解企业基础研究的外在驱动力,并为鼓励企业开展基础研究与完善中国基础研究政策体系提供思路参考。 展开更多
关键词 企业基础研究 同群效应 模仿路径 影响因素
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基于真实世界数据的观察性因果推断研究新框架(目标试验模拟)及其在中医药领域中的应用展望 被引量:1
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作者 卢存存 陈子佳 王志飞 《协和医学杂志》 CSCD 北大核心 2024年第2期422-428,共7页
“目标试验模拟”(target trial emulation)作为一种新的真实世界研究框架在近年来被正式确立,其可用于指导基于真实世界数据开展观察性因果推断研究,继而进行医疗干预有效性和安全性评价。该框架的核心思想是参照随机对照试验的原则,... “目标试验模拟”(target trial emulation)作为一种新的真实世界研究框架在近年来被正式确立,其可用于指导基于真实世界数据开展观察性因果推断研究,继而进行医疗干预有效性和安全性评价。该框架的核心思想是参照随机对照试验的原则,利用真实世界数据模拟相应的随机对照试验,进而得出干预措施与临床结局间因果关联的结论。其主要实施要点可总结为“3⁃7⁃2”,即声明因果问题、制订模拟方案和模拟目标研究3个实施步骤,纳排标准、治疗策略、干预分配、随访期、结局指标、因果比较和分析计划7个设计要素,对永恒时间偏倚和现用药者偏倚2个关键偏倚的控制。本文通过对该框架的历史与现状、实施要点、经典案例、优势与局限性及其在中医药领域中的应用前景进行概述,以期帮助中医药学者开展中医药真实世界研究,并为构建具有中医药特色的临床评价体系提供新思路。 展开更多
关键词 目标试验模拟 因果推断 比较效果研究 真实世界数据 中医药临床研究方法
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优化物理化学学科资助布局,提升科学基金资助效能
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作者 高飞雪 赵璐 +2 位作者 沈祥建 杨俊林 陈拥军 《物理化学学报》 SCIE CAS CSCD 北大核心 2024年第3期73-86,共14页
本文总结了物理化学学科代码的设立和调整变化情况,结合近十年物理化学学科研究发展趋势,论述了自2018年物理化学学科代码优化调整为催化与表界面化学和化学理论与机制以来,优化学科布局对于促进学科前沿基础研究和提升科学基金资助效... 本文总结了物理化学学科代码的设立和调整变化情况,结合近十年物理化学学科研究发展趋势,论述了自2018年物理化学学科代码优化调整为催化与表界面化学和化学理论与机制以来,优化学科布局对于促进学科前沿基础研究和提升科学基金资助效能方面起到了重要作用,提出了在优化学科布局方面的思考和建议,为后续学科发展战略提供参考。 展开更多
关键词 物理化学 学科布局 前沿研究进展 科学基金 资助效能
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