Clinical Observation on Treatment of Moderate and Severe Periodical Mastalgia with TCM Hot-wet Compress Therapy

[Objectives] To observe the clinical therapeutic efficacy of local hot-wet compress therapy of digestion ointment prescription on the patients with moderate and severe mastalgia. [Methods] Firstly,60 patients with mastalgia were selected,and divided into the experimental group and control group( 30 cases for each group). The control group was treated with acupuncture at distal point,and the experimental group was treated with TCM local hot-wet compress therapy combined with acupuncture at distal point. Then,the clinical therapeutic efficacy of two groups was compared. [Results]The experimental group was superior to the control group in relieving the breast pain,improving emotional integral,reducing breast lumps,improving lump texture,and improving TCM syndrome integral( P < 0. 05). [Conclusions]The digestion ointment prescription local hot-wet compress therapy has a significant therapeutic effect on treatment of mastalgia and can significantly improve the breast pain symptom of patients.

Treatment of 140 cerebral palsied children with a combined method based on traditional Chinese medicine(TCM)and western medicine

Objective:To observe and evaluate a method that is effective and practical for treatment of cerebral palsied(CP)children in China.Method:The patient's age and disease type and individual specific conditions were considered in choosingtherapy methods accordingly:Chinese herbs,acupuncture,auricnlar seed pressure,point finger pressing,massage,orthopedichand manipulation,physiotherapy,occupational therapy,language therapy,etc.Meanwhile we created a new CP treatment modelthat combines hospitalized treatment with family therapy.Results:The majority of CP patients improved greatly in motor andsocial adaptation capacities after treatment.Wilcoxon paired rank sum test analysis showed that there were significant differencesbetween the data before and after treatment(P<0.01).Conclusion:This combined therapy method,based on traditional Chinesemedicine and western medicine plus family supplemental therapy,is an effective and practical treatment strategy for CP children inChina.

Clinical Study on the Therapeutic Effect of Combined Traditional Chinese Medicine with Acupoint Injection and Herbal Paste Application in Treating Ovulatory Dysfunction in Polycystic Ovary Syndrome (PCOS)

Objective: To observe the therapeutic effect of combined traditional Chinese medicine (TCM) therapy with acupoint injection and herbal patch application on patients with ovulatory dysfunction associated with polycystic ovary syndrome (PCOS). Methods: A total of 80 PCOS patients who received treatment at the First Affiliated Hospital of Guangxi University of Chinese Medicine between October 2022 and March 2024 were enrolled in this study. They were randomly divided into a control group (n = 40) and an observation group (n = 40). The control group received conventional Western medical treatments, while the observation group was administered TCM combined with acupoint injection and herbal patch application. Pre- and post-treatment conditions were compared between the two groups. Results: After treatment, the overall effective rate was significantly higher in the observation group compared to the control group (P 0.05). Following treatment, both ovulation and pregnancy rates increased in both groups, but the increase was more evident in the observation group, showing a statistically significant difference (P < 0.01). Conclusion: For patients with oligoovulation or anovulation due to PCOS, the combined use of TCM, acupoint injection, and herbal patch application appears to be effective in improving systemic symptoms and achieving notable clinical outcomes.

Clinical Effects of the Qi-acupuncture Therapy of TCM on Portal Hypertension

Objective:To explore the effective prevention and treatment of portal hypertension(PH).Methods:A total of 220 patients who came to our hospital from March 2015 to October 2018 were treated.They were randomly divided into the treatment group and the control group,each with 110 cases.Before treatment,there was no significant differences in age,sex,clinical symptoms,signs,laboratory tests and color Doppler ultrasound related examinations between the 2 groups(P>0.05).Among them,the treatment group on the basis of traditional Chinese and Western medicine treatment in our hospital,the Qi-acupuncture therapy of TCM was added.The extra meridian acupoints along with acupoints were selected.The control group received conventional treatment with traditional Chinese and Western medicine in our hospital.Results:There were significant differences in clinical symptoms,signs and chemistry between groups after treatment(P<0.01).There were significant differences in test,color ultrasound related examination and so on(P<0.01).Those in the treatment group was significantly better than the control group(P<0.01).Conclusion:On the basis of the Qi-acupuncture therapy of TCM,selecting extra meridian acupoint and acupoints can effectively treat PH.

Non-pharmacological therapy of TCM for the treatment of essential hypertension

Non-pharmacotogicat treatment is an important means to control hypertension, with many advantages such as tow cost, tess medication, stable btood pressure, tess compHcations, and improved prognosis. This article reviews the research progress of non-drug treatment of hypertension in Chinese medicine in the past five years, and evaluates traditional Chinese medicine such as TCM Qigong, Wuhuo opera, Ba Duanjin and Taijiquan, and Chinese medicine acupuncture, moxibustion, massage, apptication, acupoint embedding and other traditional Chinese medicine. The effect of external treatment in hypertension control provides guidance for non-drug therapy to control hypertension.

Systematic review and meta analysis of the TCM therapy of Fuzheng and Kangai combined with chemotherapy in treating advanced NSCLC

Objective:To systematically evaluate TCM of Fuzheng and Kangai combined with chemotherapy in the treatment of Advanced NSCLC,including the efficacy and effect on the quality of life of patients.Methods:Two researchers independently searched the literature of clinical trails from Jan.2010 until Jun.2020 in the Cochrane Library,Pubmed,Embase,CBM,CNKI,WanFang Data and VIP database.Also,they had been evaluated and extracted strictly by REVMAN 5.3.Results:A total of 1303 patients were included in 15 articles.The meta analysis shows that the TCM of Fuzheng and Kangai combined with chemotherapy can improve the objective response rate[OR=2.14,95%CI(1.67,2.74),P<0.00001],disease control rate[OR=2.54,95%CI(1.88,3.42),P<0.00001]and KPS score[OR=3.28,95%CI(1.92,5.60),P<0.0001],decrease the incidence rate of liver injury[OR=0.34,95%CI(0.21,0.54),P=0.003],hemoglobin reduction[OR=0.53,95%CI(0.28,1.01),P=0.05],leukopenia[OR=0.22,95%CI(0.13,0.39),P<0.00001],thrombocytopenia[OR=0.32,95%CI(0.21,0.50),P<0.00001],toxic effects on the digestive systems[OR=0.30,95%CI(0.19,0.46),P<0.00001].Conclusions:the experimental group was better than control one in short-term efficacy and KPS score.Furthermore,the experimental group can reduce the incidence rate of myelosuppression,toxicity of digestive system and liver.

扶正消癌Ⅰ号方联合OFL方案治疗中晚期胃癌的临床观察

目的:观察扶正消癌Ⅰ号方对OFL方案治疗中晚期胃癌的减毒增效作用。方法:将60例患者随机分为2组各30例,对照组单纯采用OFL方案化疗,治疗组在对照组治疗的基础上给予扶正消癌Ⅰ号方。治疗3周为1疗程,治疗3疗程后评价近期疗效、毒副反应、生活质量和中医辨证分型疗效。结果:近期疗效治疗组为50.00%,对照组为43.33%,2组近期疗效比较,差异无显著性意义(P>0.05);毒性反应发生率、生活质量改善情况、中医辨证分型疗效2组分别比较,差异均有显著性意义(P<0.05)。结论:扶正消癌Ⅰ号方联合OFL方案治疗中晚期胃癌能显著降低毒副反应发生率,提高患者生活质量,显著改善中医临床症状,具有肯定的减毒增效作用。

INDIGESTION OF FOOD RETENTION IN CHILDREN TREATED BY ACUPUNCTURE AND MASSAGE

Objective By acupuncture plus massage to treat poor appetite induced by indigestion of food retention in children to restore their normal appetite. Methods 476 cases of indigestion of food retention in children were treated by acupuncture plus massage. Results 385 of the 476 cases were cured, and 91 cases were improved by one treatment with a total effective rate of 100%. Conclusion Acupuncture plus massage provided remarkable therapeutic effects on indigestion of food retention in children.

Therapeutic effect of Zijin capsule in liver fibrosis in rats

AIM To confirm the therapeutic effect of Zijin capsule on liver fibrosis in rat model. METHODS Model group: bovine serum albumin (BSA) Freund′s incomplete adjuvant 0 5ml was injected subdermally at d 1, d 15 , d 22 , d 29 and d 36 for primary sensitization. Seven days after the fifth injection, BSA antibody in the serum was detected by double agar diffusion method. Normal saline of 0 4ml was injected through cauda vein to BSA antibody positive rat twice a week for fifteen times. Traditional Chinese medicine (TCM) decoction group and Zijin capsule group: In the attack injection period, Chinese medicinal decoction or Zijin capsule was given ig, the others were the same as in the model group. NS was used in the control group. The collagen content of rat liver was determined by Bergman′s method and expressed as ±s . The liver pathological changes were divided into four grades and expressed as the avarage of the total rank sum. RESULTS The collagen content (mg/g) of the liver in the control group (7 2±1 9) was significantly lower than that in the other groups; it was higher in the model group (31 7±16 6) than that in the two therapeutic groups; and lower in Zijin capsule group (9 7±2 8) than that in the TCM decoction group (11 5±5 3). The pathological changes were more aggravated in the model group (37 4) than those in the two therapeutic groups; and more severe in the TCM decoction group (30.2) than in the Zijin capsule group (22.9) CONCLUSION The therapeutic effect of Zijin capsule on the model was confirmed.

Effect of Wumeiwan on Cytokines TNF-α,IL-6,IL-8,IL-10 and Expression of NF-κBp65 in Rats with Ulcerative Colitis

The effects of Wumeiwan （WMW） on TNF-α, IL-6, IL-8, IL-10 and NF-κBp65 in rats with ulcerative colitis （UC） were investigated, the curative effectiveness of WMW vs salicylazosulfapyridine （SASP） was compared, and the action mechanism was analyzed. Fifty-Six Sprague-Dawley （SD） rats were randomly divided into four groups （n=14 in each group, with equal ratio of male and female）： normal control group, model group, SASP group, and WMW group. Except normal control group, the rat UC models in the remaining three groups were established using the method of 2.4-dinitrochlorobenzene （DNCB） immunization and acetic acid local enema. The rats in model group, SASP group, and WMW group were treated with distilled water, SASP, and WMW respectively. The changes in the symptoms and signs were observed, and levels of IL-6, IL-8, TNF-α, IL-10 and the expression of NF-κBp65 in the colonic tissues were statistically analyzed. The results showed that the levels of IL-6, IL-8, and TNF-α were significantly increased （P〈0.01）, while those of IL-10 significantly reduced （P〈0.01） after establishment of rat UC models as compared with normal control group. The levels of IL-6, IL-8, and TNF-α were obviously lower, but the level of IL-10 was obviously higher in WMW and SASP groups than those in model group （P〈0.05）. The levels of IL-6, IL-8, and TNF-α were lower, while the level oflL-10 was higher in WMW group than in SASP group. NF-κBp65 was expressed negatively or weakly in normal colonic tissues. The positive expression rate of NF-κBp65 in WMW group and SASP group was obviously lower than in model group （P〈0.01）, and there was significant difference between WMW group and SASP group （P〈0.05）. It was concluded that rat UC model was established successfully. WMW could up-regulate the expression of IL-10, down-regulate the expression of TNF-α, IL-6, IL-8, and inhibit the NF-κBp65 activity to adjust immune function, indicating WMW had better curative effects on UC in rats.

Effects of four regulating-intestine prescriptions on pathology and ultrastructure of colon tissue in rats with ulcerative colitis

AIM: To observe different histomorphologic changes of ulcerative colitis (UC) rats that were treated with four regulating-intestine prescriptions (FRIP), to investigate the curative effects of FRIP and to analyze their treatment mechanism.METHODS: The UC rat model was made by the method of 2,4-dinitro chloro benzene (DNCB) immunity and acetic acid local enema. Ninety-eight SD rats were randomly divided into seven groups, namely, the normal control group, model group, salicylazosulfapyridine (SASP) group,Wumeiwan (WMW) group, Baitouwengtang (BTWT) group,Senglingbaishusan (SLBSS) group, and Tongxieyaofang (TXYF) group. Each group had 14 rats (with equal ratio of male and female). The six animal model groups of UC-SASP, TXYF, WMW, BTWT, SLBSS, TXYF-were treated by distilled water except the normal control group. Changes of the rat's general conditions after treatment were respectively observed, the colon tissue damage scores were given out, the pathology of colonic mucosa and changes of ultrastructure were analyzed.RESULTS: Different pathological changes on histology were shown after treatment by FRIP. The colon tissue damage score in model group was higher than that of FRIP groups and SASP group (q = 4.59, 4.77, P＜0.05 or q = 5.48,6.25, 5.97, P＜0.01). The scores of WMW group, BTWT group and SLBSS group were lower than that of SASP (q = 4.13, P＜0.05 or q = 5.31, 5.12, P＜0.01). There was no remarkable difference between the damage score of TXYF group and SASP group (q = 3.75, P＞0.05). In addition, some apoptosis cells were found in the pathologic control group.CONCLUSION: The model made with DNCB and acetic acid was successful, and FRIP had better curative effect and WMW was the best curative effect, BTW, SLBSS and TXYF were similar to SASP, and we discovered that apoptosis was possibly related to UC.

Clinical and experimental study of therapeutic effect of Weixibaonizhuan pills on gastric precancerous lesions

IMS To observe the therapeutic effect of Weixibaonizhuan pills on gastric precancerous lesions.METHODS Thirty patients with gastric precancerous lesions were treated with Weixibaonizhuan pills for 3 months. Of the 36 cases, 13 (361%) were mild atrophic gastritis, 14 (389%) moderate atrophic gastritis and 9 (250%) severe atrophic gastritis; among them 22 (611%) and 27 cases (750%) were accompanied with intestinal metaplasia (IM) and dysplasia (DYS) respectively. Of the 36 patients, 20 were men and 16 women, aged from 30-60 years and those aged 30-59 years accounted for 611%. The course of disease ranged from 3 months to 21 years, and 20 (556%) of them had a course of 5-10 years. The clinical manifestations were fullness of the abdomen (31 cases), abdominalgia (27 cases), anorexia (30 cases), gas eructation (26 cases), acid regurgitation (6 cases) and loose stool (9 cases). When treatment ended, the improvement of patients′ clinical symptoms, atrophy of gastric mucosa, IM and DYS were analysed.RESULTS After 3 months′ treatment with Weixibaonizhuan pills, 7 cases recovered, 11 cases were much improved, 13 cases showed some improvement, and 5 cases were ineffective; the total rate of symptomatic improvement was 861%. Of the 13 cases with mild atrophic gastritis, 11 cases changed into superficial gastritis, and 2 cases had no changes. Of the 14 cases of moderate atrophic gastritis, 4 cases changed into superficial gastritis, 7 cases changed into mild atrophic gastritis, and 3 cases had no changes. Five of 9 cases of severe atrophic gastritis were reduced to moderate atrophic gastritis, and 4 cases had no changes. The total effective rate was 778% in chronic atrophic gastritis. Of the 9 cases with mild IM, IM disappeared in 6 cases and 3 showed no change. Of the 10 cases with moderate IM, it disappeared in 2 cases, 5 cases changed to mild IM, and 3 cases had no change. One of the 4 cases of severe IM changed to moderate IM and 3 had no change. The total effective rate was 636% in IM. Of the 16 cases of mild DYS, 11 cases showed disappearance of DYS and 5 had no change. In 9 cases of moderate DYS, 2 showed disappearance, 5 changed to mild DYS and 2 had no change. Two cases of severe DYS, both showed no change. The total effective rate was 667% in DYS. Before treatment, the Ⅰ, Ⅱ, Ⅲ and Ⅳ degree positive expressions of CEA were present in 13, 12, 9 and 2 cases, respectively, whereas after treatment, the positive expressions were present in 25, 7, 3 and 1, respectively. Before treatment, the Ⅰ, Ⅱ, Ⅲ and Ⅳ degree positive expressions of PCNA were present in 16, 11, 10 and 4 respectively, but after treatment, they were present in 21, 9, 5 and 1 respectively. In short, the positive expressions of CEA and PCNA of gastric mucosa were significantly decreased after treatment (P<001).CONCLUSION Weixibaonizhuan pill has a therapeutic effect in gastric precancerous lesions..

Expression of bcl-2 oncogene in gastric precancerous lesions and its correlation with syndromes in traditional Chinese medicine

AIM: To observe the protein and mRNA expression of bcl-2 oncogene in gastric precancerous lesions (GPL) and to analyze its correlation with syndromes in traditional Chinese medicine (TCM). METHODS: Sixty-seven patients with GPL confirmed by gastroscopy and pathology were studied,including 39 cases of moderate gastric mucosal dysplasia,19 cases of severe gastric mucosa dysplasia, 9 cases of incomplete colon metaplasia. In syndrome differentiation of TCM,17 cases belonged to the syndrome of qi and yin deficiency of the spleen and stomach complicated by qi stagnation, 21 cases belonged to the syndrome of qi and yin deficiency of the spleen and stomach complicated by stomach heat, 29 cases belonged to the syndrome of qi and yin deficiency of the spleen and stomach complicated by blood stasis. Protein and mRNA expression of bcl-2 oncogene were detected by labeled streptavidin biotin (LSAB) immunohist-ochemistry and in situ hybridization respectively. RESULTS: Abnormal expression of protein and mRNA on bcl-2 oncogene was found in GPL,which increased gradually with the course of lesions. In moderate and severe gastric mucosal dysplasia and incomplete colon metaplasia,there was no difference in the expression of bcl-2 oncogene (P>0.05).In different accompanying syndromes, the expression of protein and mRNA on bcl-2 oncogene increased gradually in the following order: deficiency of both qi and yin of the spleen and stomach accompanying qi stagnation→stomach heat→blood stasis. In GPL, compared with accompanying blood stasis, there was an obvious difference in the expression of bcl-2 oncogene between the syndrome of qi and yin deficiency of the spleen and stomach and accompanying stomach heat, so did accompanying qi stagnation (the level of protein: X2=8.45, P<0.05;the level of mRNA: X2=7.35, P<0.05). CONCLUSION: Apoptosis-associated bcl-2 oncogene is abnormally expressed in GPL,which correlates with different accompanying syndromes in TCM.

EXTREMELY HIGH FREQUENCY (EHF) PUNCTURE THERAPY AND SYNDROMES OF TRADITIONAL CHINESE MEDICINE

ExtremeIy high frequency (EHF) puncture is a new method of treatment based uponbiological effects of low power electromagnetic waves of millimetric band and acupuncture theory oftraditional Chinese medicine (TCM). It is non-invasive, painless and effective. Extensiveness and variety of the specific sensations (Deqi phenomenon) during EHF-puncture re-flect intensive reactions of the patient’s organism and provide individualization of therapy. EHF-puncture is a step of integration of traditional Chinese with modern Western medicines.

Treatment of postoperative gastric cancer with Fuzheng Huoxue anticancer prescription

AIM Study on the effects of Fuzheng Huoxue anticancer prescription (Traditional Chinese Medicine) in treating gastric cancer. METHODS Sixty nine patients with gastric cancer of mid or late stage were confirmed histologically. They were divided into two groups. The treatment group included 35 cases (26 males and 9 females, 2 cases aged from 33～40 years, 18 from 41～60, 15 from 61～75, mean 58 4 years). The control group included 23 males and 11 females, 4 aged 33～40 years, 16 41～60, 14 61～75, averaging 56 8 years. The two groups were not significantly different in sex, age, clinical and pathological stages, operation mode, etc. The two group were given similar treatment. The treatment group was given Fuzheng Huoxue anticancer prescription. The cell line SGC 7901 was inoculated to the back of 30 nude mice under sterile condition. The nude mice were allocated randomly into control, traditional Chinese medicine and chemotherapeutic groups with 10 mice in each group with similar weight. Each nude mouse in control group received 0 5ml saline/day. The Fuzheng Huoxue anticancer prescreption was given to the traditional Chinese medicine group, 0 5ml/day (containing 1 5g crude drug) chamotherapentic group was injected with 1mg 5 Fu intraperitoneally once a week for 8 weeks. RESULTS Before treatment, OKT8 was 45 94±8 45%, OKT4/OKT8 was 0 89±0 19, AT Ⅲ was 29 9mg/dl±7 9mg/dl, Fa was 50 4%±24 4%, β TG was 91 0ng/dl±25 9ng/dl in treatment group; OKT8 was 49 21%±6 60%, OKT4/OKT8 was 0 94±0 20, AT Ⅲ was 32 3mg/dl±7 2mg/dl, Fa was 57 3%±24 6%, β TG was 87 5ng/dl±34 2ng/dl in controls before treatment. After treatment, OKT8 was 33 52%±7 80%, OKT4/OKT8 was 1 47±0 51, AT Ⅲ was 38 8mg/dl±5 5mg/dl, Fa was 102 6%±31 6%, β TG was 62 3ng/dl±15 1ng/dl in treatment group and OKT8 was 42 22%±7 07%, OKT4/OKT8 was 1 12±0 24, AT Ⅲ was 30 9mg/dl±8 0mg/dl, Fa was 64 6%±26 9%, β TG was 67 0ng/dl±42 1ng/dl in controls. After treatment, the T lymphocyte′s immunologic function of the patients with gastric cancer was significantly improved in the treatment group ( P <0 01). The hypercoagulability was improved ( P <0 001). OKT4/OKT8 ratio, antithrombin Ⅲ (AT Ⅲ), fibrinolytic activity, etc. were all normalized. The one year (86%), 3 year (69%) and 5 year (40%) suvival rates were increased as compared with controls, ( P <0 05). The mean tumor weighted 0 895g±0 289g in controls, 0 433g±0 177g in traditional Chinese medicine group and 0 357g±0 142g in chemotherapeutic group. The tumor inhibitory rates were 51 6% and 60 1% in traditional Chinese medicine group and chemotherapeutic group, respectively, significantly better than in the controls ( P <0 001). The mean tumor weight was 24 68±1 93g in traditional Chinese Medicine group, significantly higher than that in treatment group (22 96g±1 87g) and the controls (22 47g±2 18g). CONCLUSION Fuzheng Huoxue anticancer prescription can not only replenish vital fuction (Zheng qi), improve hypercoagulatory state, improve immunologic function and extend the survival of patient, but may also have direct inhibitory action on gastric tumor growth without side effects and toxicity.

OBSERVATION OF THE EFFECTS OF ZHENXUANYIN ON CBF OF RATS WITH VERTEBROARTERIAL ISCHEMIA AND CBF OF HEALTHY RATS

In order to observe the improvement effects of Zhenxuanyin (ZXY) to the rats vertebral artery infarction, it's prevention ability to the Pulsinelli's 4 vessel occlusion (4VO) rats model and it's influences to the normal rats brain. The infarction of the rats vertebral artery (vertebral 2 VO) and the 4VO rats model were achieved through electrocoagulation. 123 I IMP was used to trace cerebral blood flow (CBF). Except of cerebral cortex, the blood flow of each region decreased. Dosage of ZXY at 0 3 g/kg was able to normalize the decreased blood flows in cerebral regions. Healthy rats were medicated at a daily 0 3 g/kg and 1 g/kg dosage of ZXY. At the end of 1 week, they were made into 4VO model rats. No effective prevention effect was found. ZXY had no obvious effect on the CBF of normal rats. Vertebral 2 vessel occlusion is similar to clinical mild cerebral inefficient blood supply, therefore closer to the model of clinical VID. ZXY is able to normalize this incomplete compensation state, which is consistent with the curative effect on Pulsinelli's 4VO model rats. The best curative dosage of ZXY does not improve normal rats' CBF implied that ZXY used to cure regional cerebral ischemia at the acute stage does not dilate the cerebral blood vessel in the normal region, thus does not cause blood stealing in the brain 〔5〕 , Therefore, ZXY is an ideal CBF improving agent.

The use of traditional Chinese medicine internally and externally combined with auricular acupuncture point bloodletting in the treatment of vulvar leukoplakia

Vulvar leukoplakia refers to the chronic disease of degeneration and hypopigmentation of the skin and mucous membrane of the vulva with unbearable itching in women, seriously affecting the quality of life. The main treatment of western medicine for vulvar leukoplakia is the external use of glucocorticoids or estrogen, resulting to the high recurrence rate and side effects. Traditional Chinese medicine (TCM) has the characteristics of the overall concept and dialectical treatment with a variety of ways. Literature review in recent years found that the treatment of TCM decoction combined with external therapies, such as external fumigation, acupuncture and other treatments, or the combination of TCM decoction and external western medicine hormone ointment, can obtain good effects in vulvar leukoplakia. During the clinical practice, we found that the use of TCM internally and externally combined with auricular acupuncture point bloodletting was highly effective with unique advantages in the treatment of vulvar leukoplakia, providing the ideas guidance for clinicians.

Discussion on depression by thinking of t raditional Chinese medicine

Depression is a common mental disease characterized by abnormal emotional changes,which belongs to the category of“melancholia syndrome”and Chinese emotion medicine.The main clinical manifestations are mood depression,loss of interest,hallucinations,self-harm,and even suicide.Etiology and pathogenesis can be divided into“inner depression”and“outer depression”,and is related to the susceptibility of the constitution.The diagnosis can be combined with four diagnoses and new techniques.Traditional Chinese medicine(TCM)treatment methods include TCM,psychotherapy,acupuncture,music therapy and so on.TCM treatment of depression has a long history,strong symptomatic,little side effects.It is forward-looking to explore new ideas of understanding and treating depression syndrome with TCM theory,which is helpful to better“prevention before disease”.TCM therapy will certainly play an important role in the treatment of depression in the future.

Therapy of acute severe pancreatitis awaits further improvement

ＴｈｅｒａｐｙｏｆａｃｕｔｅｓｅｖｅｒｅｐａｎｃｒｅａｔｉｔｉｓａｗａｉｔｓｆｕｒｔｈｅｒｉｍｐｒｏｖｅｍｅｎｔＷＵＸｉａｎＺｈｏｎｇＳｕｂｊｅｃｔｈｅａｄｉｎｇｓｐａｎｃｒｅａｔｉｔｉｓ／ｔｈｅｒａｐｙ；ｐａｎｃｒｅａｔｉｔｉｓ／ｄｒｕｇｔｈｅｒ...