Clinical Effect and Tolerance Analysis of Photodynamic/Electroion in the Treatment of Skin Cancer and Precancerous Lesions

The study was dedicated to explore the clinical efficacy and tolerability of photodynamic/electroion therapy of skin cancer and precancerous lesions.Firstly,a total of 60 patients with skin cancer and precancerous lesions,who were admitted to the Dermatology Department of the Fifth Affiliated Hospital of Zhengzhou University from November 2013 to November 2016,were selected and divided into observation group and control group according to the random number table,with 30 patients in each group.Observation group adopted the photodynamic/electroion therapy,and control group adopted photodynamic therapy(PDT).Two groups of patients were last follow-up to December 2018,and loss of follow-up and death were taken as the end point events of follow-up.The frequency of treatment,clinical efficacy and severity of adverse reactions of the two groups were calculated,and Kaplan-Meier curves were plotted to compare the progression free survival(PFS)of the two groups.The results showed that the number of treatment times per capita in the observation group was 3.6±1.1 times,which was lower than that of in the control group(4.1±1.1 times),but the difference was not statistically significant(t=1.760,P=0.083).The total effective rate in the observation group(100.00%)was higher than that of in the control group(80.00%),and the difference was significant(P<0.05).In addition,during the treatment,both groups had adverse reactions such as burning,pain,redness,swelling and exudation of different degrees,but there was no significant difference in the severity score of adverse reactions(P>0.05).There was no statistically significant difference in the follow-up time and PFS between the two groups(P>0.05),but the recurrence rate of the observation group was significantly lower than that of the control group(P<0.05).Therefore,the clinical efficacy of photodynamic/electroion treatment in patients with skin cancer and precancerous lesions was superior to that of PDT alone,which increased the risk of tolerance.So,it is worthy of clinical promotion.

点阵CO_2激光及电离子治疗腋臭的疗效比较分析

目的:评估点阵CO2激光及电离子治疗腋臭的临床疗效及安全性。方法:采用点阵CO2激光治疗78例患者,电离子治疗95例患者,治疗前、治疗3个月后使用腋臭评分法进行评分统计,比较其疗效及不良反应。结果:点阵CO2激光治疗的78例患者经1次治疗后有效率达71.79%,其中10例患者2次治疗后有效率达99%,主要不良反应有术后轻微疼痛、渗出及色素沉着,未见出血、感染及瘢痕;电离子治疗的95例患者1次治疗后有效率为77.89%,其中8例患者2次治疗后有效率为97.00%,主要不良反应有术后疼痛、少量出血、色素沉着及瘢痕,未见感染。结论:采用点阵CO2激光及电离子治疗腋臭均有显著疗效,但点阵CO2激光治疗腋臭具有安全有效、恢复时间短及副作用轻微等优势。

苯甲酸酯类液晶的CI、EI质谱研究及比较

通过对苯甲酸酯类液晶的化学电离 ( CI)、热电离 ( EI)质谱研究及其比较可以发现 ,苯甲酸酯类液晶的EI质谱无分子离子峰 ,碎片离子明显 ,而 CI质谱分子离子峰几乎均为基峰且有苯甲酸类、醇类的互补离子峰。

支撑喉镜电离子手术治疗早期声门型喉癌

目的探讨支撑喉镜下应用多功能电离子手术治疗机切除早期声门型喉癌的新方法。方法在支撑喉镜电视显像下,应用GX-ⅢB型多功能电离子治疗机切除声门型喉癌11例。结果手术成功11例(100%)。结论该方法操作简单,安全可靠,微创,出血少,与激光切除的效果类似,是切除喉癌的一种新颖、有效的微创手段。

派特灵联合高频电离子治疗男性肛周尖锐湿疣的疗效观察

目的:分析研究派特灵联合高频电离子治疗男性肛周尖锐湿疣的疗效。方法:此次研究对象均为肛周尖锐湿疣男性患者68例,纳入起始时间2017年4月,截止时间2019年5月,以随机数表法分组,分别是对照组34例(开展高频电离子单一方案治疗)和研究组34例(开展派特灵及高频电离子联合治疗),比较两组治疗效果、不良反应改善时间、生活质量改善情况及复发情况。结果:在总体治疗效果的比较上,研究组显著优于对照组,差异有统计学意义(P<0.05);研究组治疗后生活质量评分改善幅度较对照组明显突出,差异显著(P<0.05);在不良反应改善时间的对比上,研究组较对照组明显更短,差异显著(P<0.05);在复发率的对比上,研究组较对照组明显更低,差异显著(P<0.05)。结论:在高频电离子治疗肛周尖锐湿疣期间辅助应用派特灵,可促使治疗效果得到优化,不良反应改善效果更为明显,且促使复发率有效降低,生活质量明显提升,具有推广价值。

电离子手术加斯奇康治疗会阴部尖锐湿疣

目的 :观察电离子手术加斯奇康治疗会阴部尖锐湿疣的疗效。方法 :52例患者电离子手术后肌肉注射斯奇康 ,每次1ml(支 ) ,隔日1次 ,连用14或21支。与同期60例微波、手术或液氮冷冻后口服阿西洛韦或注射干扰素对照比较。结果 :电子手术加期奇康治疗组病例治愈率明显高于单纯微波或液氮冷冻病例 ,也高于微波或液氮冷冻后口服阿西洛韦或注射干扰素病例。结论

电灼联合匹多莫德治疗尖锐湿疣疗效观察

目的观察高频电离子电灼联合匹多莫德治疗尖锐湿疣的疗效和安全性。方法将156例尖锐湿疣患者随机分为治疗组(78例)和对照组(78例),对照组单纯使用高频电离子手术治疗仪进行电灼治疗,治疗组在此基础上加用口服匹多莫德口服液口服连用2个月。结果随访3个月,治疗组痊愈70例,治愈率为89.7%,对照组痊愈56例,治愈率为71.8%,治疗组的治愈率明显高于对照组,差异有统计学意义(χ2=8.09,P<0.01);治疗组复发11例,复发率为14.1%,对照组复发24例,复发率为30.8%,复发率明显低于对照组,差异有统计学意义(χ2=6.23,P<0.05)。结论匹多莫德对电灼术治疗尖锐湿疣有明显提高其治愈率和对其复发有预防作用,能明显降低患者的复发,安全有效,具有临床推广价值。