CHINESE HUAI TANG NINE ACUPUNCTURE NEEDLES: RESEARCH ON THE NEW NINE ACUPUNCTURE NEEDLES THERAPY AND THE NEEDLING INSTRUMENTS (CONTINUED)

PART TWOThe Research on Chinese Huai TangNine Acupuncture Needles TherapyI The theoretical basis of ChineseHuai Tang Nine Needles Therapy.1) The kernel of the theoretical basis ofChinese Huai Tang Nine Needles Therapy.Chinese Huai Tang Nine Needles Therapyis to give full play to the treatment action of thespecifity and entirety of each needle. The speci-fity means that each needle has its own

Study of Mongolian Warming Needle Acupuncture Therapy

The Mongolian warming needle acupuncture therapy is a Mongolian traditional external treatment method that uses special silver needles to insert specific acupoints on the human body,and then stimulates them with warm acupuncture to achieve the purpose of disease prevention and treatment.This paper reviewed the theoretical basis,acupuncture methods,acupuncture classification,acupuncture tools,acupuncture points,indications,and contraindications of Mongolian acupuncture.Besides,it also summarized the clinical application of the Mongolian warming needle acupuncture therapy.In addition,it elaborated the its principle of regulating cold and heat in the body,leading the disease out,dialectically coordinating the whole,and changing the local part,highlighting its important position in medicine,so as to better promote clinical practice.

TREATMENT OF 247 CASES OF PROLAPSE OF LUMBAR INTERVERTEBRAL DISC WITH COMPREHENSIVE PLUM-BLOSSOM MAGNETIC NEEDLE THERAPY

Objective: To observe the therapeutic effect of comprehensive plum-blossom magnetic needle therapy on prolapse of lumbar intervertebral disc. Methods: 247 cases of prolapse of lumbar intervertebral disc were treated first with manual treatment and then with plum-blossom magnetic needle therapy and effect-increasing pad therapy at specified points and reactive points. Results: After treatment for 2 therapeutic courses,153 cases were cured accounting for 61.94%, 71 cases were markedly effective accounting for 28.75%, 22 cases were improved accounting for 8.91% and the rest one failed,accounting for 0.45%. Conclusion: The comprehensive plum-blossom magnetic needle therapy has a better therapeutic effect on prolapse of lumbar intervertebral disc.

CLINICAL OBSERVATION ON THE ACUPOINT INTRADERMAL EMBEDDING OF RINGHEADED THUMBTACK-NEEDLE THERAPY FOR HYPERPLASIA OF MAMMARY GLANDS

In the present paper, the author used acupoint intradermal embedding of ringheaded thumbtack-needle therapy combined with herbal medicine therapy to treat 110 cases of hyperplasia of mammary glands, and compared its therapeutic effect with that of herbal therapy alone. The observed indexes of the treatment were pain relief degree, the size of hyperplasic glands and the time of occurrence of marked effect. Following 3 courses of treatment,the results showed the therapeutic effect of the ringheaded thumbtack-needle needle plus herbal medicine therapy was superior to that of herbal medicine therapy alone in the above-mentioned 3 indexes (P ＜ 0.01 ).

TREATMENT OF VERTEBRAL－ARTERY TYPE CERVICAL SPONDYLOPATHY WITH NEEDLE－KNIFE THERAPY

In the present paper, 62 cases of vertebral-artery type cervical spondylopathy were treated with needie-knife therapy (acupotomy). After 2- 6 sessions of treatment, 23 cases (37. 1%) were cured, 19 (30. 7%)showed marked improvement, 15 (24.2%) had some improvement and 5 (8.1 % ) failed in the treatment. The total effective rate was 91.9 %. It indicates that acupotomy therapy is a highly effective remedy for treating vertebral-artery type cervical spndylopathy.

Accuracy of endoscopic ultrasound-guided needle aspiration specimens for molecular diagnosis of non-small-cell lung carcinoma

BACKGROUND Endoscopic ultrasonography-guided fine-needle aspiration(EUS-FNA)and endobronchial ultrasound-guided transbronchial needle aspiration(EBUS-TBNA)are highly sensitive for diagnosing and staging lung cancer.In recent years,targeted therapy has shown great significance in the treatment of non-small cell lung carcinoma(NSCLC).Using these minimally invasive techniques to obtain specimens for molecular testing will provide patients with a more convenient diagnostic approach.AIM To evaluate the feasibility and accuracy of tissue samples obtained using EUSFNA and EBUS-TBNA for molecular diagnosis of NSCLC.METHODS A total of 83 patients with NSCLC underwent molecular testing using tissues obtained from EUS-FNA or EBUS-TBNA at the Tianjin Medical University Cancer Hospital from January 2017 to June 2019.All enrolled patients underwent chest computed tomography or positron emission tomography/computed tomography prior to puncture.We detected abnormal expression of EGFR,KRAS,MET,HER2,ROS1 and anaplastic lymphoma kinase protein.Two patients failed to complete molecular testing due to insufficient tumor tissue.The clinical features,puncture records,molecular testing results and targeted treatment in the remaining 81 patients were summarized.RESULTS In a total of 99 tissue samples obtained from 83 patients,molecular testing was successfully completed in 93 samples with a sample adequacy ratio of 93.9%(93/99).Biopsy samples from two patients failed to provide test results due to insufficient tumor tissue.In the remaining 81 patients,62 cases(76.5%)were found to have adenocarcinoma,11 cases(13.6%)had squamous cell carcinoma,3 cases(3.7%)had adenosquamous carcinoma and 5 cases(6.2%)had NSCLC-not otherwise specified.The results of molecular testing showed EGFR mutations in 21 cases(25.9%),KRAS mutations in 9 cases(11.1%),ROS-1 rearrangement in 1 case(1.2%)and anaplastic lymphoma kinase-positive in 5 cases(6.2%).Twentyfour patients with positive results received targeted therapy.The total effectiveness rate of targeted therapy was 66.7%(16/24),and the disease control rate was 83.3%(20/24).CONCLUSION Tissue samples obtained by EUS-FNA or EBUS-TBNA are feasible for the molecular diagnosis of NSCLC and can provide reliable evidence for clinical diagnosis and treatment.

TREATMENT OF 67 CASES OF GASTROPTOSIS WITH ELONGATED NEEDLE(芒针)

Sixty-seven patients with gastroptosis were treated by stimulating Guanmen (ST 22)and Taiyi (ST 23) acupoints with elongated needles, obtaining a satisfactory result. Of them, 52 caseswere cured, 7 cases markedly effective and 8 cases ineffective. The total effective rate was 88%.

CLINICAL ANALYSIS TO 74 CASES OF MENOPAUSAL SYNDROME TREATED WITH SIMPLE FIRE NEEDLE

In this paper,simple fire needle pricking the points of Du（Governor）and Ren（Conception）meridians was employed to treat 74 cases of menopausal syndrome.The result showedthat 41 cases were clinically cured,17 markedly improved,15 improved and 1 ineffective,with thetotal effective rate 87％.With the advantages of extensive materials used,simple manipulation andlarge variety of indications,this method is worthy to be popularized.

CLINICAL OBSERVATION ON TREATMENT OF 60 CASES OF ASTHMA WITH RED-HOT NEEDLE IN THE DOG DAYS

In the present paper, a total of 109 asthma patients were randomly divided into treatment group (red hot needle, n=62) and control group (conventional acupuncture, n=47). The treatment was conducted beginning from the first day of the first 10 day period of the Dog Days. After successive two years’ treatment, results showed that of the 62 and 47 cases in treatment and control groups, 16 and 7 were cured basically, 37 and 16 had remarkable improvement, 8 and 12 were ameliorated, 1 and 10 failed in the treatment, with the effective rate being 98.4% and 78.7% respectively, displaying that the therapeutic effect of treatment group was significantly superior to that of control group (P<0.01).

INFLUENCE OF DIFFERENT NEEDLE-RETAINING DURATION ON CEREBRAL HEMODYNAMICS OF CEREBRAL PARALYSIS CHILDREN

Objective: To investigate the effects of different needle-retaining duration on cerebral hemodynamics in cerebral paralysis (CP) children. Methods: A total of 20 cases of CP children were subjected into this study. Changes of systolic peak value (Vs), blood flow velocity at the end-diastolic phase (Ved), mean velocity (Vm), pulsation index (PI) and resistance index (RI) of the cerebral hemodynamics before and after performing JIN’s Three-Needling Therapy with the needles retained for 30 min (group A) and 5 min (group B) were observed by using transcranial Doppler ultrasonography (TCD). Results: After acupuncture, the blood flow in the middle cerebral artery (MCA), anterior cerebral artery (ACA) and posterior cerebral artery (PCA) was accelerated, and the resistance of blood vessels decreased. The effect of needle-retaining-30 min was better than that of needle-retaining-5 min. Conclusion: In treating cerebral paralysis by using JIN’s Three-Needling Therapy, sufficient stimulation provided by needle remaining is an important factor for achieving satisfactory therapeutic effects.

Efficacy and safety of awn needle in the treatment of lumbar disc herniation:A meta-analysis

Objective:To evaluate the intervention effect of awn needle in the treatment of lumbar disc herniation through meta-analysis.Methods:In CNKI,Wanfang Data,PubMed,VIP and other databases,we searched the clinical observation studies on the treatment of patients with lumbar disc herniation with awn needle.The methodological quality of the included studies was evaluated using Cochrane 5.1.0 bias risk assessment criteria and Jadad scale.Revman 5.3 software was used for meta-analysis.Results:A total of 14 randomized controlled trials involving 1186 patients were included,with 595 in the awn needle treatment group and 591 in the control group.Meta-analysis showed that the awn needle treatment group was better than that of the control group in the total effective rate[RR=1.17;95%CI(1.12,1.22);Z=6.66;P<0.00001];the awn needle treatment group was better than the control group in ameliorating VAS score[WMD=-1.07,95%CI(-1.19,-0.95),Z=17.87,P<0.00001];the awn needle treatment group was better than the control group in ameliorating JOA score[WMD=3.18,95%CI(2.64,3.71),Z=11.57,P<0.00001];the awn needle treatment group was better than the control group in the amelioration of ADL score[SMD=2.44,95%CI(0.54,4.35),Z=2.52,P=0.01];the awn needle treatment group was better than the control group in the improvement of SLRT angle[WMD=12.71,95%CI(3.21,22.21),Z=2.62,P=0.009].Conclusion:Awn needle treatment can improve the total effective rate of patients with lumbar disc herniation,relieve the pain of patients,improve the straight leg elevation angle of patients,alleviate the disease development,relieve the symptoms,and improve the quality of life of patients.It is worthy of clinical application.

Effect of Wei’s triple nine needling therapy on flash visual evoked potentials in rats with traumatic optic neuropathy

Objective:To investigate the effect of Wei’s triple nine needling therapy on the N2-P2 wave of the flash visual evoked potential(FVEP)in rats of the of the transverse directional pulling model.Methods:Thirty-six Wistar rats were randomly grouped,nine were in normal control group without any treatment,and the remaining 27 were surgically modelled in the right eyes.Eighteen of these rats were randomly divided into a Wei’s triple nine needling therapy group and a model group of nine rats each after the TON model was made using the transverse quantitative retraction method.The other 9 rats were sham-operated,and only the optic nerve was exposed without retraction.On the next day of modelling,the Wei’s triple nine needling therapy group was treated with Wei’s triple nine needling therapy for 20 minutes/1 time/1 day for 14 days.The model group,sham-operated group and normal control group were not intervened.Wei's triple nine acupoints were represented as follows:1st link:"Jingming"(BL1)and"Chengqi"(ST1);2nd link:"Sizhukong"(SJ23)penetrating"Taiyang"(EX-HN5);and the third:"Fengchi"(GB 20)and"Taichong"(LV3).The FVEP of each group was observed on 1d,7d and 14d.The FVEP of each group was observed on 1d,7d and 14d.Results:Compared with the model group,the N2 wave latency and P2 wave latency were shortened in the Wei’s triple nine needling therapy on 1d(P<0.05,P<0.01);on 7d,their N2 wave latency was shortened(P<0.01)and the N2-P2 wave amplitude was increased compared with the model group(P<0.05);on 14d,their P2 wave latency was shortened(P<0.05)and the N2-P2 wave amplitude was increased.There was no statistical difference in N2 wave latency,P2 wave latency and N2-P2 wave amplitude in the sham-operated group on 1d,7d and 14d(P>0.05).The delayed N2 and P2 wave latencies in the model group did not improve from 1d to 14d(P>0.05)and the amplitude decreased throughout,showing a significant difference on 14d compared to 1d(P<0.05).In contrast,the N2 wave latency in Wei’s triple nine needling therapy group was not significantly different until 7d to 14d(P<0.05);its P2 wave latency,although significantly delayed from 1d to 7d(P<0.05),recovered on 14d and reached a level that was not statistically different from 1d and 7d(P>0.05).There was also no significant decrease in N2-P2 wave amplitude between 1d and 14d in Wei’s triple nine needling therapy group(P>0.05).Conclusion:In this experiment,the TON rat model was successfully established by the transverse quantitative retraction method,and the treatment of TON rats with Wei’s triple nine needling therapy reduced the P2 wave delay of the FVEP electrophysiological signal and increased the N2-P2 amplitude,which had a certain positive effect on the repair of optic nerve injury,probably related to its effect of improving the conduction function of the optic nerve and protecting the retinal ganglion cells that had not been degenerated and necrosed.

TREATMENT OF 18 CASES OF TRIGEMINAL NEURALGIA WITH ELONGATED NEEDLE

In this paper, a total of 18 cases of primary trigeminal neuralgia were treated with elongated needle. Of the 18 cases, 5 were male and 15 female, ranging in age from 27 to 58 years and in disease duration from 3 days to 8 years. Main acupoints used were Taiyang (EX-HN 5) to Xiaguan (ST 7, for penetration needling), Xiajiache, Fengchi (GB 20), Yanglingquan (GB 34) and Taichong (LR 3). The treatment was given once daily, with 12 sessions being a therapeutic course. After 2 courses of treatment, of the 18 cases, 10 cases were cured, 7 experienced improvement in pain and one failed in the treatment, with an effective rate of 94.4%. The key point for treating trigeminal neuralgia is applying penetrative needling from EX-HN 5 to ST 7 to achieve ideal needling sensations.

CLINICAL OBSERVATION ON TREATMENT OF STUBBORN HICCUP BY ACUPUNCTURE WITH DIFFERENT NEEDLE RETAINING TIME

Purpose:Observe the effect of different duration of needle-retention on acupuncture treatment of stubborn hiccup. Methods: 85 cases of stubborn hiccup patients are randomly divided into control group (n=40) and treatment group(n=45) according to their visiting time. For patients of control group, acupuncture needles (in both scalp points and body acupoints) are retained for 30 min, while for patients of treatment group, the needles inserted in the body acupoints are retained for 1 hr, and that inserted in scalp-point is retained for more than 6 hrs. The treatment is conducted once daily, continuously for 5 times. Results: The cure rate of treatment group is 88.9% (that for deficiency syndrome is 85.3%), and that of control group is 65% (that for deficiency syndrome is 53.3%).There is a significant difference between two groups in the cure rate (P<0.05). The cure rates for excess syndrome of two groups both are 100%.Conclusion: Longer retention of acupuncture needle has a better therapeutic effect for deficiency-syndrome type hiccup.

Acupuncture and Needle-Stimulation, Differences in Concepts and Methods

Based on related elaboration of the Yellow Emperor’s Canon of Medicine, this article analyzed and summarized the clinical meaning, application principles and the basic operating methods of Traditional Acupuncture (TA), and demonstrated that the TA is completely different to modern needle stimulation. TA has a specific application background, direct-viewing thinking mode and clear operational connotation. The key of operation in TA is how to grasp and control Qi, which typically reflect the unique image of the Chinese civilization with intuitive perceptual characteristics of thinking. In contrast, modern needle-stimulation uses needles as a stimulus, to activate a series of physical and functional reactions in a body. There have great differences between the two. It was indicated that correctly understanding with the basic principle and specific meaning of TA is very important in acupuncture clinical and research works.

基于文献计量分析皮内针疗法适宜病症与临床应用进展

目的基于文献计量分析皮内针疗法的临床文献,探讨皮内针疗法的适宜病症与临床应用进展。方法通过计算机检索中国知网(CNKI)、万方数据库(Wanfang data)和维普中文期刊数据库中与皮内针疗法相关的临床研究文献,应用文献计量学的方法对皮内针疗法发文量、病谱和适宜病症进行分析。结果临床涉及论文共2220篇,近10年发文量显著增长。皮内针疗法临床涉及病症208种。一级适宜病症为手术后疼痛、失眠症、偏瘫、面神经麻痹;二级适宜病症为肩痛、颈椎病、癌痛、膝骨关节炎、腰椎间盘移位、便秘、头痛;三级适宜病症为带状疱疹、遗尿、放化疗后不良反应、变应性鼻炎、呃逆、面肌痉挛;四级适宜病症包括痛经、高血压、糖尿病、胃肠功能紊乱、痹证、吞咽障碍、腰扭伤、肥胖症。结论皮内针疗法是近年来的临床研究热点,其治疗疾病以痛症居多,其次为各类慢性病。不同针具中,揿针的应用受到广泛关注。

《内经》“关刺”联合“合谷刺”治疗不宁腿综合征疗效观察

目的 观察《内经》“关刺”联合“合谷刺”治疗不宁腿综合征(restless legs syndrome, RLS)的临床疗效。方法 将100例RLS患者随机分为治疗组(50例,脱落1例)和对照组(50例,脱落2例)。治疗组给予“关刺”联合“合谷刺”治疗,阳陵泉、膝关、丘墟采用关刺法,伏兔、丰隆、漏谷采用合谷刺法;对照组给予假针刺治疗。治疗前后采用国际RLS评定量表(international restless leg syndrome scale, IRLSS)评价患者不宁腿严重程度,采用RLS生活质量量表(RLS quality of Life, RLSQoL)评价患者生活质量,采用失眠严重指数量表(insomnia severity index, ISI)评价患者的睡眠情况,并比较两组临床疗效。结果 治疗组总有效率为91.8%,显著高于对照组的41.7%(P<0.01)。治疗后,治疗组IRLSS评分低于治疗前和对照组(P<0.01),治疗组RLSQoL评分高于治疗前和对照组(P<0.01),治疗组ISI评分低于治疗前和对照组(P<0.01)。对照组治疗前后各项评分比较,差异无统计学意义(P>0.05)。结论 《内经》“关刺”联合“合谷刺”可显著改善RLS患者临床症状,在中医学理论的指导下拓展了《内经》五刺法的临床应用。

揿针疗法联合ERAS在妇科腹腔镜围手术期应用研究

目的:探讨揿针疗法联合加速康复外科(ERAS)在妇科腹腔镜围手术期应用效果。方法:选取江西省妇幼保健院2022年1月—2023年1月收治的腹腔镜手术患者85例作为研究对象。采用前瞻性随机对照分组原则,将患者分为对照组(42例)和观察组(43例)。对照组采用ERAS干预,此基础上,观察组采用揿针疗法干预。比较两组临床相关康复指标,术后并发症发生情况,术后疼痛程度视觉模拟评分法(VAS)及术后胃肠功能障碍(POGD)评分。结果:观察组术后首次下床时间为(16.25±3.03)h、肛门排气时间为(11.88±2.56)h、拔除尿管时间为(13.67±3.15)h,均短于对照组的(19.74±3.54)、(14.05±2.87)、(19.25±3.81)h,留置引流管时间为(1.41±0.29)d、住院时间为(5.41±1.09)d,均短于对照组的(1.65±0.32)、(7.02±1.24)d(P<0.05)。观察组术后恶心、呕吐、肠胀气、尿潴留等并发症发生率均低于对照组(P<0.05);观察组术后6、12、24 h,VAS评分均低于对照组(P<0.05)。术后2、6、12、24 h,两组的VAS评分的时间效应、组间效应及交互效应,差异均有统计学意义(P<0.05)。观察组术后24 h POGD评分低于对照组(P<0.05);两组出院时POGD评分均低于术后24 h(P<0.05);两组出院时POGD评分比较,差异无统计学意义(P>0.05)。结论:揿针疗法联合ERAS可减轻妇科腹腔镜手术患者术后疼痛及胃肠功能障碍,加速术后康复,缩短住院时间,对妇科良性疾病患者围手术期康复具有重要应用价值。

温针配合穴位贴敷及药物干预乳腺癌化疗相关性恶心呕吐的临床研究

目的观察温针配合穴位贴敷及药物干预乳腺癌化疗相关性恶心呕吐(chemotherapy induced nausea and vomiting,CINV)的临床疗效。方法将110例乳腺癌术后辅助化疗患者随机分为观察组和对照组,每组55例。对照组于化疗前30 min接受静脉滴注注射用盐酸托烷司琼治疗,观察组在对照组基础上于化疗前1 d接受温针配合穴位贴敷治疗。观察两组化疗前后不同时间点恶心、呕吐反应症状评分及血清5-羟色胺(5-hydroxytryptamine,5-HT)水平的变化情况,并比较两组CINV发生率。结果观察组CINV发生率为34.5%,明显低于对照组的56.4%,差异具有统计学意义(P<0.05)。两组化疗后第3 d恶心、呕吐反应症状评分均较同组化疗前显著上升,化疗后第5、7 d恶心、呕吐反应症状评分均较同组化疗第3 d显著下降,差异均具有统计学意义(P<0.05)。观察组化疗后第3、5、7 d恶心、呕吐反应症状评分均明显低于对照组,差异均具有统计学意义(P<0.05)。两组化疗后第7 d血清5-HT水平均较同组化疗前显著上升(P<0.05)。观察组化疗后第7 d血清5-HT水平明显低于对照组,差异具有统计学意义(P<0.05)。结论温针配合穴位贴敷及药物干预能降低乳腺癌CINV的发生率,有助于缓解恶心、呕吐症状,其机制可能与降低5-HT水平有关。