Objective To explore the therapeutic effect on primary dysmenorrhea treated with the embedding catgut therapy so as to discover a better therapeutic method for the treatment of this disease. Methods One hundred and fi...Objective To explore the therapeutic effect on primary dysmenorrhea treated with the embedding catgut therapy so as to discover a better therapeutic method for the treatment of this disease. Methods One hundred and fifty cases were randomized into 3 groups, 50 cases in each one. In the embedding catgut group, the embedding catgut therapy was applied to Sānyīnjiāo (三阴交 SP 6), Cìliáo (次髎 BL 32) and Guānyuán (关元 CV 4). In the acupuncture group, the conventional acupuncture therapy was applied to Guānyuán (关元 CV 4), Sānyīnjiāo (三阴交 SP 6), Dìjī (地机 SP 8) and Shíqīzhuī (十七椎 EX-B 8). In the western medicine group, indometacin was prescribed for oral administration, 25 mg, three times a day and fenbid was supplemented for the aggravated pain, 300 mg, twice a day. One session of treatment was one month in each group and 3 sessions were required totally. Before and after treatment, the symptom scores of dysmenorrhea were observed. Results The symptom scores of dysmenorrhea were all reduced obviously in three groups after treatment (all P0.05). The result in the embedding catgut group was much more apparent as compared with that in the western medicine group (P0.01) and the acupuncture group (P0.05) separately. Of 49 cases in the embedding catgut group, 32 cases (65.3%) were cured clinically, 10 cases (20.4%) effective remarkably, 6 cases (12.2%) effective and 1 case (2.0%) failed. The total effective rate was 98.0%. Conclusion The embedding catgut therapy achieves the significant efficacy for primary dysmenorrhea. This therapy is simple in practice and deserves to be promoted in clinic.展开更多
Objective To systematically evaluate the effect of acupoint catgut embedding therapy (ACET) for simple obesity. Methods Computer retrieval was used for randomized controlled trials on the treatment effect of simple ...Objective To systematically evaluate the effect of acupoint catgut embedding therapy (ACET) for simple obesity. Methods Computer retrieval was used for randomized controlled trials on the treatment effect of simple obesity with ACET in databases of the China National Knowledge Infrastructure (CNKI), Wanfang Data system, and the China Biology Medicine disc (CBMDisc). The Jadad Quality Scale was used in the evaluation of included studies. The outcome indicators were analyzed with the Review Manage 5.1 software. Results A total of 16 randomized controlled trials were included finally. The meta-analysis result showed that compared with the control group, there was statistically significance on the total efficiency of using ACET for simple obesity [OR=2.51, 95% confidence interval (1.74, 3.63), Z=4.91, P〈0.000 01]. The analysis on the literature quality showed that there was only 2 article marked as 3 points. The other 25 articles marked ≤2 points. The quality of published articles was generally low. There were publication biases and the blinding method was seldom used, the losses of follow-up / drop oup / withdraw were reported with less. There were 27 acupoints used in the treatment, which mainly included Tianshu (天枢ST 25), Zhongwan (中脘 CV 12), Fenglong (丰隆 ST 40), Shufen (水分 CV 9), Qihai (气海 CV 6), Sanyinjiao (三阴交 SP 6), Zusnli (足三里 ST 36), Ashi point, Daheng (大横 SP 25). The five kinds of catgut embedding needle were injection needles + acupuncture needle, specialized catgut embedding needle, spinal needle, triangular needle, and skin suture needle. Conclusion There is definite efficiency of using ACET in the treatment of simple obesity. However, the clinical efficiency still lacks of sufficient evidences. Therefore, further clinical research should be conducted in the providing of reliable evidences in the clinical decision-making in the future.展开更多
Objective To compare the therapeutic effect of catgut embedding combined with diet plus exercise with that of diet plus exercise in treating simple obesity complicated with abnormal blood fat. Methods A prescription o...Objective To compare the therapeutic effect of catgut embedding combined with diet plus exercise with that of diet plus exercise in treating simple obesity complicated with abnormal blood fat. Methods A prescription of diet plus exercise was given to the patients in a control group, and catgut embedding was added to the prescription in a treatment group. It was given once every 15 days for the 1st three treatments, and once every month for the 2^nd three treatments. Six treatments constituted a therapeutic course. Body weight and blood fat were measured before and half a year since treatment. Results After treatment, BMI, TO, TG and LDL were very significantly improved in the treatment group (P〈0.01), and BMI and TG were very significantly (P〈0.01) and TO and LDL were significantly (P〈0.05) improved in the control group. HDL was not obviously improved in both groups (P〉0.05). The improvement of TO, TG and LDL in the treatment group was significantly more than that in the control group (P〈0.01), but no difference in improvement of BMI and HDL was found between the two groups (P〉0.05). Conclusion The therapy of diet plus exercise was effective in body weight reduction and lowering blood fat in patients with simple obesity complicated with abnormal blood fat, and catgut embedding used in combination was even better in lowering blood fat.展开更多
Objective:To evaluate the effectiveness and safety of acupoint catgut embedding(ACE)in combination with Chinese herbal medicine(CHM)in treating chronic urticaria(CU).Methods:We thoroughly searched Embase,PubMed,Cochra...Objective:To evaluate the effectiveness and safety of acupoint catgut embedding(ACE)in combination with Chinese herbal medicine(CHM)in treating chronic urticaria(CU).Methods:We thoroughly searched Embase,PubMed,Cochrane Library,Web of Science,China National Knowledge Infrastructure(CNKI),Wangfang database,Chinese Scientific Journal Database(VIP),and Chinese biomedical literature database(SinoMed)for relevant studies from inception until May 2022.Randomized controlled trials(RCTs)on ACE combined with CHM for CU were included.Literature search,data extraction,and risk of bias assessment were independently conducted by two authors.Results:A total of 15 RCTs with 1065 participants were included in this review.Five trials reported that the combined therapy showed a higher total effective rate,and four trials reported that the combined therapy was associated with a lower level of serum immunoglobulin E.Furthermore,two,four,and four trials reported that the combined therapy was more effective in reducing itching degree,size,and number of wheals,respectively.The combined therapy was reported to be associated with a lower recurrence rate in three trials,and with a fewer adverse reaction rate in two trials.Conclusions:ACE in combination with CHM appears to be a safe and effective therapy for patients with CU.Given the relatively low quality of the included trials,these findings should be interpreted cautiously.Further high-quality RCTs are needed to confirm our findings.展开更多
Aim: To observe the therapeutic effect of acupoint catgut embedding in the treatment of epilepsy rats. Methods: 40 Wistar rats were randomly and evenly divided into normal control, model, medication (Natrii Valproas s...Aim: To observe the therapeutic effect of acupoint catgut embedding in the treatment of epilepsy rats. Methods: 40 Wistar rats were randomly and evenly divided into normal control, model, medication (Natrii Valproas syrup), and catgut embedding groups. Epilepsy model was established by intraperitoneal injection of sodium penicillin (0.4 mu/100 g), twice every week, continuously for 4 weeks. Electroencephalograph (EEG) was used as the index for assessing the effect of catgut embedding on epilepsy. Results: In epilepsy rats of model group, the amplitude and frequency of EEG increased significantly in comparison with control group (P<0.05). While the amplitude and frequency of EEG of catgut embedding group and medication group were all significantly lower than those of model group (P<0.05, 0.01). The frequency of EEG of catgut embedding group was significantly lower than that of medication group (P<0.05). These findings show that both acupoint catgut embedding and medication can apparently improve epileptic electrical activities of the brain in the rat, and the effect of catgut embedding is better than that of medication in lowering the frequency of EEG.展开更多
Background:Obesity,as an epidemic public health issue in the world today,not only brings a heavy medical burden to society but also seriously affects people’s quality of life.In the context of new evidence for the ef...Background:Obesity,as an epidemic public health issue in the world today,not only brings a heavy medical burden to society but also seriously affects people’s quality of life.In the context of new evidence for the efficacy of acupoint catgut embedding(ACE)in abdominal obesity(AO),it is necessary to elucidate the mechanism of ACE for AO.The intestinal flora is closely associated with obesity,and the study of its intestinal flora may provide evidence to clarify the mechanism of obesity treatment by ACE.Methods:75 participants will be recruited in this study,including 60 eligible female patients diagnosed with AO and 15 healthy female participants.60 female AO patients will be randomized to ACE group,sham ACE group,and waiting list(WL)group in a ratio of 1:1:1.Patients in two ACE groups will receive one ACE treatment per week for 12 consecutive weeks,and in the WL group will not receive any treatment;only their data will be extracted.The primary outcome is the mean change in body mass index.Secondary effects include waist circumference,body weight,the visual analog score of appetite,and the Gastrointestinal Symptom Rating Scale.High-throughput 16S ribosomal ribonucleic acid gene sequencing will be used to detect intestinal flora in each group before and after the intervention.Conclusion:The results of this trial are expected to identify the critical intestinal flora causing AO and the target intestinal flora of AO regulated by ACE,providing further theoretical support for ACE in the clinical treatment of obesity.展开更多
Acupoint catgut embedding therapy(ACET),filling the gaps of traditional Chinese medicine acupuncture treatment,has been widely used for the treatment of many diseases with significant effects.The aim of this paper is ...Acupoint catgut embedding therapy(ACET),filling the gaps of traditional Chinese medicine acupuncture treatment,has been widely used for the treatment of many diseases with significant effects.The aim of this paper is to obtain polyglycollide acid(PGA)fibers with higher performance at a lower cost,and ensure that PGA can meet the clinical requirements as well.PGA fibers with different diameters were spun as embedding materials.The mechanical performance,thermodynamic and biodegradable properties of PGA fibers were studied under different spinning process parameters,including spinning speed,drawing temperature and stretching ratio.The experimental results showed that the optimum spinning parameters were the spinning speed at 150 m/min,the drawing temperature of 45 ℃,and the stretching ratio of 4.0.The initial modulus of PGA fibers was 3.876 N/tex.The crystallization degree was 68% and the degradation performance was in consistent with treatment cycle of patients.展开更多
Objective:To explore the clinical effect of embedding thread combined with Jianpi Qushi Huayu ointment in the treatment of bronchiectasis in remission period,and to observe the effect on the level of inflammatory cyto...Objective:To explore the clinical effect of embedding thread combined with Jianpi Qushi Huayu ointment in the treatment of bronchiectasis in remission period,and to observe the effect on the level of inflammatory cytokines.Methods:150 patients with bronchiectasis in remission period were divided into three groups(50 cases in each group),western medicine group(treated with salmeterol fluticasone and low dose erythromycin),combined group(treated with Jianpi Qushi Huayu plaster),observation group(treated with western medicine+Jianpi Qushi Huayu plaster+embedding thread),and the clinical treatment of the three groups were compared.Result:before and after treatment,the improvement of TCM syndrome score,the improvement of pulmonary ventilation index,the improvement of inflammatory cytokines,and the change of adverse reactions.Results:the treatment efficiency of the observation group and the combination group was significantly higher than that of the western medicine group P The peak level of expiratory flow velocity,the maximum expiratory flow,the forced expiratory volume in one second and the ratio of forced expiratory volume in one second to vital capacity in the observation group and the combined group were significantly better than those in the western medicine group and the pre-treatment level(P<0.05),and the improvement in the observation group was better than that in the combined group After treatment,the expression of IL-13,IL-10 and IL-4 in the combined group was significantly better than that in the western medicine group and before treatment(P<0.05),and the improvement in the observation group was better than that in the combined group;there was no significant difference in the incidence of adverse reactions among the three groups(P>0.05).Conclusion:catgut embedding combined with Jianpi Qushi Huayu ointment can significantly alleviate the related clinical symptoms and signs,effectively control the further aggravation of the disease,improve the lung function of patients,regulate the level of inflammatory cytokines to reduce the degree of inflammatory reaction,and do not significantly aggravate the adverse reactions of drugs.展开更多
Objective To observe the clinical effect of acupoint catgut embedding combined with abdominal acupuncture for treatment of abdominal obesity under the theoretical guidance of regulating the three energizer.Methods One...Objective To observe the clinical effect of acupoint catgut embedding combined with abdominal acupuncture for treatment of abdominal obesity under the theoretical guidance of regulating the three energizer.Methods One hundred and twenty patients were randomly divided into acupoint catgut embedding group(group A),abdominal acupuncture group(group B),acupoint catgut embedding combined with abdominal acupuncture group(group C) and blank control group(group D) based on blocked random method,with 30 cases each;the first three groups based on the principle of regulating three energizer were respectively given acupoint catgut embedding at Zhongwan(中脘 CV12),Tianshu(天枢 ST 25),Yinjiao(阴交 CV 7),Zhigou(支沟 TE 6),Guanyuan(关元 CV 4),Zusanli(足三里 ST 36) with catgut embedding once every 7 days,three times for each course of treatment,abdominal acupuncture once every3 days,seven times for each course of treatment.Results The therapeutic effect of each group after treatment was respectively 46.7%(14/30),43.3%(13/30),76.7%(23/30) and 26.7%(8/30),with statistically significant difference.For comparison of waist circumference difference,there was no statistical significance between acupoint catgut embedding combined with abdominal acupuncture and acupoint catgut embedding group(P=0.54),and for comparison of weight difference,there was statistical significance in terms of therapeutic effect between acupoint catgut embedding combined with abdominal acupuncture and A,B,D groups(4.49±0.59 vs 2.64±0.53,2.87±0.44,1.45±0.26,all P〈0.05).Conclusion Acupoint catgut embedding combined with abdominal acupuncture had the best effect in terms of total effective rate for treatment of abdominal obesity,equivalent therapeutic effect to simple acupoint catgut embedding in terms of waist circumference reduction,and the best therapeutic effect in terms of weight reduction.展开更多
Objective This review aimed to systematically evaluate the evidence on the effects of acupoint catgut embedding (ACE) therapy for patients with polycystic ovary syndrome (PCOS). Methods Five databases (CBM, CNKI,...Objective This review aimed to systematically evaluate the evidence on the effects of acupoint catgut embedding (ACE) therapy for patients with polycystic ovary syndrome (PCOS). Methods Five databases (CBM, CNKI, Wanfang Database, VlP Database, and PubMed) were searched to identify relevant studies published before June 2027. The outcomes were resumption of menstruation and serum levels of testosterone (T). The methodological quality of the included studies was judged using the Cochrane risk of bias tool. The overall level of evidence was judged by the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria. Results Twenty- five randomized controlled trials were included. ACE therapy significantly lowered serum T levels, and patients receiving ACE treatment reported resumption of menstruation. However, these results should be interpreted with caution due to a high risk of randomization and blinding bias, and likely publication bias. The level of evidence for resumption of menstruation and serum T levels was assessed as "low" and "low", respectively, using GRADE. Conclusion The current evidence on ACE therapy for PCOS is insufficient to draw firm conclusions due to the poor methodological quality. Future well- designed trials are needed to validate the therapeutic efficacy, safety, and mechanisms of ACE in patients with PCOS.展开更多
Objective To observe the clinical therapeutic effect of catgut embedding therapy for treatment of menopausal obesity. Methods Sixty-four cases of menopausal obesity patients were randomly divided into two groups, 32 c...Objective To observe the clinical therapeutic effect of catgut embedding therapy for treatment of menopausal obesity. Methods Sixty-four cases of menopausal obesity patients were randomly divided into two groups, 32 cases in each group. In control group, the diet control was employed. And based on it, in observation group, catgut embedding therapy was apphed at Zusanli (足三里 ST 36), Sanyinjiao (三阴交 SP 6), matched with other points in line with syndrome differentiation. Therapeutic effect evaluated by changes of weight, Body Mass Index (BMI), waist circumference and Kupperman index before and after treatment was observed. Results The total effective rate for treating obesity and menopausal syndrome was 90.6% (29/32), 87.5% (28/32) respectively in observation group, superior to those of 46.9% (15/32), 40.6% (13/32) in control group (both P〈0.05); weight, BMI, waist circumference and Kupperman index in both groups improved distinctively after treatment (all P〈0.05), and changes were more significantly in observation group than those in control group (all P〈0.05). Conclusion For treating menopausal obesity, catgut embedding therapy not only has a good therapeutic effect on weight loss, but also improves menopausal syndrome.展开更多
Objective:To observe the clinical effect of acupoint catgut embedding combined with auricular plaster therapy in the treatment of children with vocal tic disorders.Methods:Catgut embedding was performed at the acupoin...Objective:To observe the clinical effect of acupoint catgut embedding combined with auricular plaster therapy in the treatment of children with vocal tic disorders.Methods:Catgut embedding was performed at the acupoints Bǎihuì(百会GV20),Shéntíng(神庭GV24),Dàzhuī(大椎GV14),Shēnzhù(身柱GV12),Fèishū(肺俞BL13),and Wèishū(胃俞BL21),and then auricular plaster sticking was applied to the acupoints Yānhòu(咽喉TG3),Fèi(肺CO14),Wèi(胃CO4),Jiāogǎn(交感AH6 a),Pízhìxià(皮质下AT4).Results:After treatment,the Yale Global Tic Severity Scale(YGTSS)scores of the patients were significantly reduced(P<0.05),5 cases were clinically cured,8 cases remarkably effective,12 cases effective,5 cases ineffective,and the total effective rate was 83.33%.Conclusion:Acupoint catgut embedding combined with auricular plaster therapy for vocal tic disorders was effective,being worthy of clinical popularization.展开更多
OBJECTIVE: To evaluate the clinical effectiveness and safety of acupoint catgut embedding and acupuncture on simple obesity by Meta-analysis. METHODS: Studies on clinical randomized controlled trials of acupoint catgu...OBJECTIVE: To evaluate the clinical effectiveness and safety of acupoint catgut embedding and acupuncture on simple obesity by Meta-analysis. METHODS: Studies on clinical randomized controlled trials of acupoint catgut embedding for simple obesity which were published from January 2015 to November 2020 were searched in Cochrane Central Register of Control Trials(Central), Pub Med, China Science and Technology Journal Database, China National Knowledge Infrastructure Database and Wanfang databases. And those that met the inclusion criteria were screened. Rev Man5.3 was used for Meta-analysis. The “Risk of Bias” tool was used to evaluate the quality of included studies. R studio software was used for the measurement of publication bias. RESULTS: A total of 33 studies were included for Metaanalysis, including 2685 patients with simple obesity. Meta-analysis results showed the comparison of effectiveness rate was relative risk(RR) = 1.12, 95%CI(1.08, 1.16), body mass index(BMI) was mean difference(MD) =-1.12, 95%CI(-2.09,-0.14), waist circumference was MD =-2.14, 95%CI(-4.22,-0.06), and body mass was MD =-2.36, 95%CI(-3.99,-0.73). On the basis of diet and exercise intervention, the effectiveness rate [RR = 1.12, 95%CI(1.05, 1.19)], BMI [MD =-0.88, 95%CI(-1.35,-0.40)], waist circumference [MD =-1.10, 95%CI(-4.27, 2.07)], and body mass [MD =-0.68, 95%CI(-2.90, 1.54)]. The risk of bias of included literatures was low. CONCLUSIONS: Acupoint catgut embedding therapy was slightly better than acupuncture therapy in most of the outcomes. Moreover, the treatment frequency of acupoint catgut embedding is less with larger stimulation intensity, which is more conducive to clinical promotion.展开更多
OBJECTIVE:To systematically review and analyze the effect of acupuncture and acupoint catgut embedding in treatment of abdominal obesity to provide a more reasonable clinical treatment regimen.METHODS:Ten databases we...OBJECTIVE:To systematically review and analyze the effect of acupuncture and acupoint catgut embedding in treatment of abdominal obesity to provide a more reasonable clinical treatment regimen.METHODS:Ten databases were searched as of August 2022:the English databases Pub Med,Embase,Cochrane Library,Web of Science,Wiley,and Scopus and the Chinese databases China National Knowledge Infrastructure Database,China Science and Technology Journal Database,Wanfang,and Sino Med/Chinese Biomedical Literature Database.Randomized controlled trials(RCTs)of acupuncture and acupoint catgut embedding as the main interventions to treat abdominal obesity were extracted.The investigators imported the citations into End Note version X9.1 for deduplication,screening,extraction,and integration.The risk of bias in the included RCTs was assessed according to the Cochrane Handbook.Rev Man 5.4 software was used to conduct a Meta-analysis of RCTs that met the inclusion criteria.RESULTS:Thirteen RCTs(1069 patients)were included in this study,and the data of eleven RCTs(966 patients)were include in the Meta-analysis.The results showed that acupoint catgut embedding can significantly change the weight and waist circumference of patients with abdominal obesity when compared to sham acupuncture or no treatment[mean difference(MD)=2.32,95%confidence interval(CI)(1.88,2.76),P<0.00001],[MD=3.47,95%CI(1.99,4.94),P<0.00001].The change in hip circumference after acupuncture was also significant[MD=0.89,95%CI(0.12,1.66),P=0.02].CONCLUSION:This study found that acupuncture and acupoint catgut embedding can effectively treat abdominal obesity,therefore,these interventions can be used as clinical supplements and alternative therapies.The diagnostic criteria of the existing studies and the intervention measures of the control group are not unified.It will be necessary to improve the clinical study protocols and expand the sample size to further validate the reliability of the results obtained of this study.展开更多
OBJECTIVE:To investigate the effects of acupoint catgut embedding for 3 weeks on lung tissue,blood immunoglobulin E(IgE)and interleutin-4(IL-4),brain tissue microglia x-42(OX-42)and toll-like receptor-2(TLR-2)in rats ...OBJECTIVE:To investigate the effects of acupoint catgut embedding for 3 weeks on lung tissue,blood immunoglobulin E(IgE)and interleutin-4(IL-4),brain tissue microglia x-42(OX-42)and toll-like receptor-2(TLR-2)in rats with allergic rhinitis of lung deficiency type.METHODS:Forty-five female Sprague-Dawley rats were randomly divided for two times.The first time,they were randomly divided into model group and blank group(Group C)according to 2∶1,and the second time,the model group were randomly divided into model control group(Group B)and intervention treatment group(Group A)according to 1∶1.15 in each group.For Group A and Group B,the lung deficiency model was made by"sulfur–moxa fumigation",and then the allergic rhinitis model was established by"ovalbumin(OVA)sensitization".Then catgut embedding was performed at acupoints in Group A and not in Group B.After 3 weeks,collect lung tissue samples for hematoxylin-eosin staining,then take blood to observe the concentration of IgE and IL-4,and finally take brain tissue to observe the results of OX-42 and TLR-2.RESULTS:IgE level(μg/m L)was(3.11±0.20)in the Group A,(4.19±0.44)in the Group B,and(2.29±0.30)in the Group C(all P<0.001).IL-4 level(pg/mL)was(14.2±0.7)in the Group A,(18.6±2.4)in the Group B,and(11.4±1.2)for the Group C(all P<0.001).The mean OD for OX-42 is(0.1728±0.0016)in the Group A,(0.1810±0.0046)in the Group B and(0.1674±0.0025)in the Group C(all P<0.001).CONCLUSION:Although 3 weeks of acupoint catgut embedding already showed obvious efficacy on rats with allergic rhinitis,the allergic reaction in the body still continued.To achieve further treatment,prolonging the catgut embedding time is necessary.展开更多
OBJECTIVE:To explore the difference of catgut embedding effect between acupoints and non-acupoints in patients with abdominal obesity(AO).METHODS:In this multicenter,double-blind,randomized controlled trial,all subjec...OBJECTIVE:To explore the difference of catgut embedding effect between acupoints and non-acupoints in patients with abdominal obesity(AO).METHODS:In this multicenter,double-blind,randomized controlled trial,all subjects were randomly assigned into the acupoint catgut embedding(ACE)group and control group(catgut embedding at non-acupoints).With a 12-week actual intervention period and a 4-week period of follow-up.Waist circumference(WC),body weight,body mass index(BMI),hip circumference(HC)and appetite were applied and assessed at baseline and after 6,12 and 16 weeks.RESULTS:After the total intervention phase(12 weeks),the WC,body weight,BMI,HC and visual analogue scale scores of appetite,decreased significantly in the two groups as compared to the baseline(P<0.001).Meanwhile,after the 4-week follow-up,the indicators still decreased significantly in the ACE group(P<0.001).At 12 and 16 weeks,catgut embedding at acupoints showed significantly advantages to non-acupoints in WC and appetite(P<0.05).No serious adverse events were observed in ACE group and control group.CONCLUSIONS:Catgut embedding at acupoints and non-acupoints are all effective and safe for AO.ACE can effectively treat AO as expected and deliver lasting results.展开更多
OBJECTIVE:To assess the efficacy of acupoint catgut embedding(ACE)for simple obesity in preclinical animal experiments.METHODS:We searched the following 14 electronic databases:PubM ed,Cochrane Library,EMBASE,Oriental...OBJECTIVE:To assess the efficacy of acupoint catgut embedding(ACE)for simple obesity in preclinical animal experiments.METHODS:We searched the following 14 electronic databases:PubM ed,Cochrane Library,EMBASE,Oriental Medicine Advanced Searching Integrated System,KoreaMed,Korean Studies Information Service System,Science-on,Research Information Sharing Service,Korea Citation Index,Korea Traditional Knowledge Portal,China Network Knowledge Infrastructure Database,Wanfang Database,Chinese Science and Technology Journal Database,and Chinese Biology Medicine Database,from inception to November 2021 without language limitation.The assessment was performed according to the guidelines of Animal Research:Reporting of in vivo experiments;and Metaanalysis was performed using Reviewer Manager 5.4.1 software.RESULTS:Twenty-four studies involving 813 animals were selected.Meta-analysis showed that ACE was beneficial for weight control[n=40,MD=-50.63,95%CI(-57.59,-43.67),P<0.00001,I 2=0%]and reduced the Lee index[n=40,MD=-18.79,95%CI(-20.01,-17.57),P<0.00001,I 2=0%].However,when efficacy of ACE was compared with that of manual acupuncture,electroacupuncture,or oilistat therapy,statistical difference was not observed between the two groups.CONCLUSIONS:This systematic review suggests that ACE may be efficacious in treating obesity.Moreover,the analyses highlighted the necessity to perform welldesigned,higher-quality experiments.展开更多
Prof.Min LI adopted acupoint catgut embedding at Zhōngwǎn(中脘CV12),Tiānshū(天枢ST25),Wèishū(胃俞BL21),Dàchángshū(大肠俞BL25),Zúsānlǐ(足三里ST36),Sānyīnjiāo(三阴交SP6),and Tàichōng...Prof.Min LI adopted acupoint catgut embedding at Zhōngwǎn(中脘CV12),Tiānshū(天枢ST25),Wèishū(胃俞BL21),Dàchángshū(大肠俞BL25),Zúsānlǐ(足三里ST36),Sānyīnjiāo(三阴交SP6),and Tàichōng(太冲LR3),and combined with auricular plaster therapy at Wèi(胃CO4),Dacháng(大肠CO7),Gān(肝CO12),Jiāogǎn(交感AH6 a),Nèifēnmì(内分泌CO18)for the treatment of 18 cases of bulimia nervosa(BN).The result was that 9 cases were clinically cured,6 cases improved,3 case ineffective,and the total effec-tive rate was 83.33%,no obvious adverse reactions.The therapeutic effect of acupoint catgut embedding combined with auricular plaster therapy for BN is good,without side effects.展开更多
Objective To observe the therapeutic effect of catgut embedding treatment on bilateral Zúsānlǐ(足三里ST 36) combined with Huangqi Ejiao decoction (黄芪阿胶汤) orally taken. Methods Patients with anemia due ...Objective To observe the therapeutic effect of catgut embedding treatment on bilateral Zúsānlǐ(足三里ST 36) combined with Huangqi Ejiao decoction (黄芪阿胶汤) orally taken. Methods Patients with anemia due to blood loss after major operation were randomly divided into a control group and an observation group. There were 30 cases in the control group which were treated by blood transfusion and 32 cases in the observation group which were treated by catgut embedding on bilateral Zúsānlǐ (足三里ST 36) after local anesthesia combined with oral administration of self-made Huangqi Ejiao decoction (黄芪阿胶汤). The herbs included Huangqi (黄芪Radix Scutellariae Milk Veteh)10 g, Ejiao (阿胶Colla Corii Asini Donkey-hide Gelatin)10 g, Danggui (当归 Radix Angelicae Sinensin Chinese Angelica)10 g, Baizhu (白术 Radix A tractyloes Macrocephalae Large-headed Atractylodes) 10 g, Dangshen ( 党参 Radix Codonopsis Dangshen)20 g, Danshen (丹参 Salvia Miltiorrhiza Root of Red Rooted Salvia) 10 g, Honghua ( 红花 Carthamus Tinctorious Safflower) 10 g, Shudi (熟地 Rehmannia Glutinosa Prepared Rhizome of Rehmannia) 20 g, etc. After 1 d, 3 d, 7 d, 15 d, 21 d, RBC, Hb, IgM, IgG were tested. Results In the control group, Hb and RBC count immediately went up in the beginning, that peaked on the 7^th day and kept gently after. While in the observation group, there was a minimal increase in Hb and RBC in the beginning, followed by a sharp increase during 15-21 d, and peaked on the 21^th day. There was a significant difference between the observation group and the control group(P〈0.05). While, the level of IgM, IgG rose markedly in the observation group, with a significant difference between the two groups (P〈O. 01). Conclusion Catgut embedding treatment on bilateral Zúsānlǐ (足三里 ST 36) combined with oral administration of Huangqi Ejiao decoction (黄芪阿胶汤) can improve anemia due to blood loss after operation, and likewise increase the level of IgM and IgG.展开更多
Obesity type 2 diabetes mellitus is a common metabolic disease in clinical practice,and its prevalence is increasing rapidly with the aging of the population and changes in lifestyle.Acupuncture,as a distinctive thera...Obesity type 2 diabetes mellitus is a common metabolic disease in clinical practice,and its prevalence is increasing rapidly with the aging of the population and changes in lifestyle.Acupuncture,as a distinctive therapy,has its unique advantages in the treatment of obesity type 2 diabetes and has an irreplaceable role in a variety of treatment methods.The author organized the literature on acupuncture and its related therapies to prevent and treat obesity type 2 diabetes in recent years and found that acupuncture and its associated therapies to prevent and treat obesity type 2 diabetes mainly include:simple acupuncture,electroacupuncture,acupoint catgut embedding therapy,auricular-plaster therapy and other treatments,all of which can safely and effectively improve clinical symptoms,acupuncture and its related therapies to treat obesity type 2 diabetes has a broad prospect,worthy of further clinical promotion.展开更多
基金Supported by Project of Educational Bureau,Hubei Province:B20105103
文摘Objective To explore the therapeutic effect on primary dysmenorrhea treated with the embedding catgut therapy so as to discover a better therapeutic method for the treatment of this disease. Methods One hundred and fifty cases were randomized into 3 groups, 50 cases in each one. In the embedding catgut group, the embedding catgut therapy was applied to Sānyīnjiāo (三阴交 SP 6), Cìliáo (次髎 BL 32) and Guānyuán (关元 CV 4). In the acupuncture group, the conventional acupuncture therapy was applied to Guānyuán (关元 CV 4), Sānyīnjiāo (三阴交 SP 6), Dìjī (地机 SP 8) and Shíqīzhuī (十七椎 EX-B 8). In the western medicine group, indometacin was prescribed for oral administration, 25 mg, three times a day and fenbid was supplemented for the aggravated pain, 300 mg, twice a day. One session of treatment was one month in each group and 3 sessions were required totally. Before and after treatment, the symptom scores of dysmenorrhea were observed. Results The symptom scores of dysmenorrhea were all reduced obviously in three groups after treatment (all P0.05). The result in the embedding catgut group was much more apparent as compared with that in the western medicine group (P0.01) and the acupuncture group (P0.05) separately. Of 49 cases in the embedding catgut group, 32 cases (65.3%) were cured clinically, 10 cases (20.4%) effective remarkably, 6 cases (12.2%) effective and 1 case (2.0%) failed. The total effective rate was 98.0%. Conclusion The embedding catgut therapy achieves the significant efficacy for primary dysmenorrhea. This therapy is simple in practice and deserves to be promoted in clinic.
基金Supported by the Naional Natural Science Fund Project of China:81072883,81173342
文摘Objective To systematically evaluate the effect of acupoint catgut embedding therapy (ACET) for simple obesity. Methods Computer retrieval was used for randomized controlled trials on the treatment effect of simple obesity with ACET in databases of the China National Knowledge Infrastructure (CNKI), Wanfang Data system, and the China Biology Medicine disc (CBMDisc). The Jadad Quality Scale was used in the evaluation of included studies. The outcome indicators were analyzed with the Review Manage 5.1 software. Results A total of 16 randomized controlled trials were included finally. The meta-analysis result showed that compared with the control group, there was statistically significance on the total efficiency of using ACET for simple obesity [OR=2.51, 95% confidence interval (1.74, 3.63), Z=4.91, P〈0.000 01]. The analysis on the literature quality showed that there was only 2 article marked as 3 points. The other 25 articles marked ≤2 points. The quality of published articles was generally low. There were publication biases and the blinding method was seldom used, the losses of follow-up / drop oup / withdraw were reported with less. There were 27 acupoints used in the treatment, which mainly included Tianshu (天枢ST 25), Zhongwan (中脘 CV 12), Fenglong (丰隆 ST 40), Shufen (水分 CV 9), Qihai (气海 CV 6), Sanyinjiao (三阴交 SP 6), Zusnli (足三里 ST 36), Ashi point, Daheng (大横 SP 25). The five kinds of catgut embedding needle were injection needles + acupuncture needle, specialized catgut embedding needle, spinal needle, triangular needle, and skin suture needle. Conclusion There is definite efficiency of using ACET in the treatment of simple obesity. However, the clinical efficiency still lacks of sufficient evidences. Therefore, further clinical research should be conducted in the providing of reliable evidences in the clinical decision-making in the future.
文摘Objective To compare the therapeutic effect of catgut embedding combined with diet plus exercise with that of diet plus exercise in treating simple obesity complicated with abnormal blood fat. Methods A prescription of diet plus exercise was given to the patients in a control group, and catgut embedding was added to the prescription in a treatment group. It was given once every 15 days for the 1st three treatments, and once every month for the 2^nd three treatments. Six treatments constituted a therapeutic course. Body weight and blood fat were measured before and half a year since treatment. Results After treatment, BMI, TO, TG and LDL were very significantly improved in the treatment group (P〈0.01), and BMI and TG were very significantly (P〈0.01) and TO and LDL were significantly (P〈0.05) improved in the control group. HDL was not obviously improved in both groups (P〉0.05). The improvement of TO, TG and LDL in the treatment group was significantly more than that in the control group (P〈0.01), but no difference in improvement of BMI and HDL was found between the two groups (P〉0.05). Conclusion The therapy of diet plus exercise was effective in body weight reduction and lowering blood fat in patients with simple obesity complicated with abnormal blood fat, and catgut embedding used in combination was even better in lowering blood fat.
基金This research was supported by Key Research Program of the Chinese Academy of Sciences(ZDRW-ZS-2021-1-2).
文摘Objective:To evaluate the effectiveness and safety of acupoint catgut embedding(ACE)in combination with Chinese herbal medicine(CHM)in treating chronic urticaria(CU).Methods:We thoroughly searched Embase,PubMed,Cochrane Library,Web of Science,China National Knowledge Infrastructure(CNKI),Wangfang database,Chinese Scientific Journal Database(VIP),and Chinese biomedical literature database(SinoMed)for relevant studies from inception until May 2022.Randomized controlled trials(RCTs)on ACE combined with CHM for CU were included.Literature search,data extraction,and risk of bias assessment were independently conducted by two authors.Results:A total of 15 RCTs with 1065 participants were included in this review.Five trials reported that the combined therapy showed a higher total effective rate,and four trials reported that the combined therapy was associated with a lower level of serum immunoglobulin E.Furthermore,two,four,and four trials reported that the combined therapy was more effective in reducing itching degree,size,and number of wheals,respectively.The combined therapy was reported to be associated with a lower recurrence rate in three trials,and with a fewer adverse reaction rate in two trials.Conclusions:ACE in combination with CHM appears to be a safe and effective therapy for patients with CU.Given the relatively low quality of the included trials,these findings should be interpreted cautiously.Further high-quality RCTs are needed to confirm our findings.
文摘Aim: To observe the therapeutic effect of acupoint catgut embedding in the treatment of epilepsy rats. Methods: 40 Wistar rats were randomly and evenly divided into normal control, model, medication (Natrii Valproas syrup), and catgut embedding groups. Epilepsy model was established by intraperitoneal injection of sodium penicillin (0.4 mu/100 g), twice every week, continuously for 4 weeks. Electroencephalograph (EEG) was used as the index for assessing the effect of catgut embedding on epilepsy. Results: In epilepsy rats of model group, the amplitude and frequency of EEG increased significantly in comparison with control group (P<0.05). While the amplitude and frequency of EEG of catgut embedding group and medication group were all significantly lower than those of model group (P<0.05, 0.01). The frequency of EEG of catgut embedding group was significantly lower than that of medication group (P<0.05). These findings show that both acupoint catgut embedding and medication can apparently improve epileptic electrical activities of the brain in the rat, and the effect of catgut embedding is better than that of medication in lowering the frequency of EEG.
基金supported by The Youth Special of Yunnan Province Ten-thousand Plan(YNWR-QNBJ-2019-257)the Human Resources and Social Security Department of Yunnan Province and Yunnan Provincial Science Plan Project-Joint of Traditional Chinese Medicine(2017FF117-011,2019FF002-021,202101AZ070001-096)the Science&Technology Department of Yunnan Province.
文摘Background:Obesity,as an epidemic public health issue in the world today,not only brings a heavy medical burden to society but also seriously affects people’s quality of life.In the context of new evidence for the efficacy of acupoint catgut embedding(ACE)in abdominal obesity(AO),it is necessary to elucidate the mechanism of ACE for AO.The intestinal flora is closely associated with obesity,and the study of its intestinal flora may provide evidence to clarify the mechanism of obesity treatment by ACE.Methods:75 participants will be recruited in this study,including 60 eligible female patients diagnosed with AO and 15 healthy female participants.60 female AO patients will be randomized to ACE group,sham ACE group,and waiting list(WL)group in a ratio of 1:1:1.Patients in two ACE groups will receive one ACE treatment per week for 12 consecutive weeks,and in the WL group will not receive any treatment;only their data will be extracted.The primary outcome is the mean change in body mass index.Secondary effects include waist circumference,body weight,the visual analog score of appetite,and the Gastrointestinal Symptom Rating Scale.High-throughput 16S ribosomal ribonucleic acid gene sequencing will be used to detect intestinal flora in each group before and after the intervention.Conclusion:The results of this trial are expected to identify the critical intestinal flora causing AO and the target intestinal flora of AO regulated by ACE,providing further theoretical support for ACE in the clinical treatment of obesity.
基金“111 Project” Biomedical Textile Materials Science and Technology,China(No.B07024)
文摘Acupoint catgut embedding therapy(ACET),filling the gaps of traditional Chinese medicine acupuncture treatment,has been widely used for the treatment of many diseases with significant effects.The aim of this paper is to obtain polyglycollide acid(PGA)fibers with higher performance at a lower cost,and ensure that PGA can meet the clinical requirements as well.PGA fibers with different diameters were spun as embedding materials.The mechanical performance,thermodynamic and biodegradable properties of PGA fibers were studied under different spinning process parameters,including spinning speed,drawing temperature and stretching ratio.The experimental results showed that the optimum spinning parameters were the spinning speed at 150 m/min,the drawing temperature of 45 ℃,and the stretching ratio of 4.0.The initial modulus of PGA fibers was 3.876 N/tex.The crystallization degree was 68% and the degradation performance was in consistent with treatment cycle of patients.
基金2020 Hebei provincial research project of Chinese medicine(No.2020374)
文摘Objective:To explore the clinical effect of embedding thread combined with Jianpi Qushi Huayu ointment in the treatment of bronchiectasis in remission period,and to observe the effect on the level of inflammatory cytokines.Methods:150 patients with bronchiectasis in remission period were divided into three groups(50 cases in each group),western medicine group(treated with salmeterol fluticasone and low dose erythromycin),combined group(treated with Jianpi Qushi Huayu plaster),observation group(treated with western medicine+Jianpi Qushi Huayu plaster+embedding thread),and the clinical treatment of the three groups were compared.Result:before and after treatment,the improvement of TCM syndrome score,the improvement of pulmonary ventilation index,the improvement of inflammatory cytokines,and the change of adverse reactions.Results:the treatment efficiency of the observation group and the combination group was significantly higher than that of the western medicine group P The peak level of expiratory flow velocity,the maximum expiratory flow,the forced expiratory volume in one second and the ratio of forced expiratory volume in one second to vital capacity in the observation group and the combined group were significantly better than those in the western medicine group and the pre-treatment level(P<0.05),and the improvement in the observation group was better than that in the combined group After treatment,the expression of IL-13,IL-10 and IL-4 in the combined group was significantly better than that in the western medicine group and before treatment(P<0.05),and the improvement in the observation group was better than that in the combined group;there was no significant difference in the incidence of adverse reactions among the three groups(P>0.05).Conclusion:catgut embedding combined with Jianpi Qushi Huayu ointment can significantly alleviate the related clinical symptoms and signs,effectively control the further aggravation of the disease,improve the lung function of patients,regulate the level of inflammatory cytokines to reduce the degree of inflammatory reaction,and do not significantly aggravate the adverse reactions of drugs.
文摘Objective To observe the clinical effect of acupoint catgut embedding combined with abdominal acupuncture for treatment of abdominal obesity under the theoretical guidance of regulating the three energizer.Methods One hundred and twenty patients were randomly divided into acupoint catgut embedding group(group A),abdominal acupuncture group(group B),acupoint catgut embedding combined with abdominal acupuncture group(group C) and blank control group(group D) based on blocked random method,with 30 cases each;the first three groups based on the principle of regulating three energizer were respectively given acupoint catgut embedding at Zhongwan(中脘 CV12),Tianshu(天枢 ST 25),Yinjiao(阴交 CV 7),Zhigou(支沟 TE 6),Guanyuan(关元 CV 4),Zusanli(足三里 ST 36) with catgut embedding once every 7 days,three times for each course of treatment,abdominal acupuncture once every3 days,seven times for each course of treatment.Results The therapeutic effect of each group after treatment was respectively 46.7%(14/30),43.3%(13/30),76.7%(23/30) and 26.7%(8/30),with statistically significant difference.For comparison of waist circumference difference,there was no statistical significance between acupoint catgut embedding combined with abdominal acupuncture and acupoint catgut embedding group(P=0.54),and for comparison of weight difference,there was statistical significance in terms of therapeutic effect between acupoint catgut embedding combined with abdominal acupuncture and A,B,D groups(4.49±0.59 vs 2.64±0.53,2.87±0.44,1.45±0.26,all P〈0.05).Conclusion Acupoint catgut embedding combined with abdominal acupuncture had the best effect in terms of total effective rate for treatment of abdominal obesity,equivalent therapeutic effect to simple acupoint catgut embedding in terms of waist circumference reduction,and the best therapeutic effect in terms of weight reduction.
文摘Objective This review aimed to systematically evaluate the evidence on the effects of acupoint catgut embedding (ACE) therapy for patients with polycystic ovary syndrome (PCOS). Methods Five databases (CBM, CNKI, Wanfang Database, VlP Database, and PubMed) were searched to identify relevant studies published before June 2027. The outcomes were resumption of menstruation and serum levels of testosterone (T). The methodological quality of the included studies was judged using the Cochrane risk of bias tool. The overall level of evidence was judged by the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria. Results Twenty- five randomized controlled trials were included. ACE therapy significantly lowered serum T levels, and patients receiving ACE treatment reported resumption of menstruation. However, these results should be interpreted with caution due to a high risk of randomization and blinding bias, and likely publication bias. The level of evidence for resumption of menstruation and serum T levels was assessed as "low" and "low", respectively, using GRADE. Conclusion The current evidence on ACE therapy for PCOS is insufficient to draw firm conclusions due to the poor methodological quality. Future well- designed trials are needed to validate the therapeutic efficacy, safety, and mechanisms of ACE in patients with PCOS.
文摘Objective To observe the clinical therapeutic effect of catgut embedding therapy for treatment of menopausal obesity. Methods Sixty-four cases of menopausal obesity patients were randomly divided into two groups, 32 cases in each group. In control group, the diet control was employed. And based on it, in observation group, catgut embedding therapy was apphed at Zusanli (足三里 ST 36), Sanyinjiao (三阴交 SP 6), matched with other points in line with syndrome differentiation. Therapeutic effect evaluated by changes of weight, Body Mass Index (BMI), waist circumference and Kupperman index before and after treatment was observed. Results The total effective rate for treating obesity and menopausal syndrome was 90.6% (29/32), 87.5% (28/32) respectively in observation group, superior to those of 46.9% (15/32), 40.6% (13/32) in control group (both P〈0.05); weight, BMI, waist circumference and Kupperman index in both groups improved distinctively after treatment (all P〈0.05), and changes were more significantly in observation group than those in control group (all P〈0.05). Conclusion For treating menopausal obesity, catgut embedding therapy not only has a good therapeutic effect on weight loss, but also improves menopausal syndrome.
基金Guangdong Province Graduate Education Innovation Project:No.2017SFKC13。
文摘Objective:To observe the clinical effect of acupoint catgut embedding combined with auricular plaster therapy in the treatment of children with vocal tic disorders.Methods:Catgut embedding was performed at the acupoints Bǎihuì(百会GV20),Shéntíng(神庭GV24),Dàzhuī(大椎GV14),Shēnzhù(身柱GV12),Fèishū(肺俞BL13),and Wèishū(胃俞BL21),and then auricular plaster sticking was applied to the acupoints Yānhòu(咽喉TG3),Fèi(肺CO14),Wèi(胃CO4),Jiāogǎn(交感AH6 a),Pízhìxià(皮质下AT4).Results:After treatment,the Yale Global Tic Severity Scale(YGTSS)scores of the patients were significantly reduced(P<0.05),5 cases were clinically cured,8 cases remarkably effective,12 cases effective,5 cases ineffective,and the total effective rate was 83.33%.Conclusion:Acupoint catgut embedding combined with auricular plaster therapy for vocal tic disorders was effective,being worthy of clinical popularization.
基金Supported by National Administration of Traditional Chinese Medicine Project:Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine (No. ZYYCXTD-C-202006)。
文摘OBJECTIVE: To evaluate the clinical effectiveness and safety of acupoint catgut embedding and acupuncture on simple obesity by Meta-analysis. METHODS: Studies on clinical randomized controlled trials of acupoint catgut embedding for simple obesity which were published from January 2015 to November 2020 were searched in Cochrane Central Register of Control Trials(Central), Pub Med, China Science and Technology Journal Database, China National Knowledge Infrastructure Database and Wanfang databases. And those that met the inclusion criteria were screened. Rev Man5.3 was used for Meta-analysis. The “Risk of Bias” tool was used to evaluate the quality of included studies. R studio software was used for the measurement of publication bias. RESULTS: A total of 33 studies were included for Metaanalysis, including 2685 patients with simple obesity. Meta-analysis results showed the comparison of effectiveness rate was relative risk(RR) = 1.12, 95%CI(1.08, 1.16), body mass index(BMI) was mean difference(MD) =-1.12, 95%CI(-2.09,-0.14), waist circumference was MD =-2.14, 95%CI(-4.22,-0.06), and body mass was MD =-2.36, 95%CI(-3.99,-0.73). On the basis of diet and exercise intervention, the effectiveness rate [RR = 1.12, 95%CI(1.05, 1.19)], BMI [MD =-0.88, 95%CI(-1.35,-0.40)], waist circumference [MD =-1.10, 95%CI(-4.27, 2.07)], and body mass [MD =-0.68, 95%CI(-2.90, 1.54)]. The risk of bias of included literatures was low. CONCLUSIONS: Acupoint catgut embedding therapy was slightly better than acupuncture therapy in most of the outcomes. Moreover, the treatment frequency of acupoint catgut embedding is less with larger stimulation intensity, which is more conducive to clinical promotion.
基金Supported by National Key Research and Development Project:Clinical Evaluation of the Interventional Techniques for Abdominal Obesity(No.2019YFC1710102)。
文摘OBJECTIVE:To systematically review and analyze the effect of acupuncture and acupoint catgut embedding in treatment of abdominal obesity to provide a more reasonable clinical treatment regimen.METHODS:Ten databases were searched as of August 2022:the English databases Pub Med,Embase,Cochrane Library,Web of Science,Wiley,and Scopus and the Chinese databases China National Knowledge Infrastructure Database,China Science and Technology Journal Database,Wanfang,and Sino Med/Chinese Biomedical Literature Database.Randomized controlled trials(RCTs)of acupuncture and acupoint catgut embedding as the main interventions to treat abdominal obesity were extracted.The investigators imported the citations into End Note version X9.1 for deduplication,screening,extraction,and integration.The risk of bias in the included RCTs was assessed according to the Cochrane Handbook.Rev Man 5.4 software was used to conduct a Meta-analysis of RCTs that met the inclusion criteria.RESULTS:Thirteen RCTs(1069 patients)were included in this study,and the data of eleven RCTs(966 patients)were include in the Meta-analysis.The results showed that acupoint catgut embedding can significantly change the weight and waist circumference of patients with abdominal obesity when compared to sham acupuncture or no treatment[mean difference(MD)=2.32,95%confidence interval(CI)(1.88,2.76),P<0.00001],[MD=3.47,95%CI(1.99,4.94),P<0.00001].The change in hip circumference after acupuncture was also significant[MD=0.89,95%CI(0.12,1.66),P=0.02].CONCLUSION:This study found that acupuncture and acupoint catgut embedding can effectively treat abdominal obesity,therefore,these interventions can be used as clinical supplements and alternative therapies.The diagnostic criteria of the existing studies and the intervention measures of the control group are not unified.It will be necessary to improve the clinical study protocols and expand the sample size to further validate the reliability of the results obtained of this study.
基金General Program of the National Natural Science Foundation of China:Regulatory Mechanism of Acupoint Catgut Embedding via Axonal Reflex on Neurogenic Inflammation in Allergic Rhinitis(No.81273985)General Program of the National Natural Science Foundation of China:the Study on the Mechanism of Acupoint Catgut Embedding Therapy for Allergic Rhinitis Based on the Coupling of"Acupoint Nasal Mucosal Sensory Nerve Dendritic Cells"(No.81473523)National Science and Technology Support Program for the Twelfth Five-Year Plan:the Study on Clinical Effect and Operation Standard of Catgut Embedding at Acupoints in Treating Allergic Rhinitis(No.2015BA I04B00)。
文摘OBJECTIVE:To investigate the effects of acupoint catgut embedding for 3 weeks on lung tissue,blood immunoglobulin E(IgE)and interleutin-4(IL-4),brain tissue microglia x-42(OX-42)and toll-like receptor-2(TLR-2)in rats with allergic rhinitis of lung deficiency type.METHODS:Forty-five female Sprague-Dawley rats were randomly divided for two times.The first time,they were randomly divided into model group and blank group(Group C)according to 2∶1,and the second time,the model group were randomly divided into model control group(Group B)and intervention treatment group(Group A)according to 1∶1.15 in each group.For Group A and Group B,the lung deficiency model was made by"sulfur–moxa fumigation",and then the allergic rhinitis model was established by"ovalbumin(OVA)sensitization".Then catgut embedding was performed at acupoints in Group A and not in Group B.After 3 weeks,collect lung tissue samples for hematoxylin-eosin staining,then take blood to observe the concentration of IgE and IL-4,and finally take brain tissue to observe the results of OX-42 and TLR-2.RESULTS:IgE level(μg/m L)was(3.11±0.20)in the Group A,(4.19±0.44)in the Group B,and(2.29±0.30)in the Group C(all P<0.001).IL-4 level(pg/mL)was(14.2±0.7)in the Group A,(18.6±2.4)in the Group B,and(11.4±1.2)for the Group C(all P<0.001).The mean OD for OX-42 is(0.1728±0.0016)in the Group A,(0.1810±0.0046)in the Group B and(0.1674±0.0025)in the Group C(all P<0.001).CONCLUSION:Although 3 weeks of acupoint catgut embedding already showed obvious efficacy on rats with allergic rhinitis,the allergic reaction in the body still continued.To achieve further treatment,prolonging the catgut embedding time is necessary.
基金Yunnan Expert Workstation-Liang Fanrong Station:Study and Transformation of Classical Syndrome Differentiation System on Acupuncture and Moxibustion(No.202305AF150072)Yunnan Province Ten-thousand Plan:Youth Special-Guo Taipin(No.YNWR-QNBJ-2019-257)+2 种基金Yunnan Provincial Science Project:Study on the Bidirectional Regulation Mechanism of Central Network of ShuMu Catgut Embedding in Abdominal Obesity of Stomach Heat-Spleen Deficiency Type Which based on Multimodal Technique(No.2017FF117-011)Study on the Central Mechanism of Synergistic Potentiation of Shu-Mu Catgut Embedding in Abdominal Obesity(No.2019FF002-021)Study on the Brain Network Mechanism of Shu-Mu Catgut Embedding in Abdominal Obesity which based on Multi-Modal Technique(No.202101AZ070001-096)。
文摘OBJECTIVE:To explore the difference of catgut embedding effect between acupoints and non-acupoints in patients with abdominal obesity(AO).METHODS:In this multicenter,double-blind,randomized controlled trial,all subjects were randomly assigned into the acupoint catgut embedding(ACE)group and control group(catgut embedding at non-acupoints).With a 12-week actual intervention period and a 4-week period of follow-up.Waist circumference(WC),body weight,body mass index(BMI),hip circumference(HC)and appetite were applied and assessed at baseline and after 6,12 and 16 weeks.RESULTS:After the total intervention phase(12 weeks),the WC,body weight,BMI,HC and visual analogue scale scores of appetite,decreased significantly in the two groups as compared to the baseline(P<0.001).Meanwhile,after the 4-week follow-up,the indicators still decreased significantly in the ACE group(P<0.001).At 12 and 16 weeks,catgut embedding at acupoints showed significantly advantages to non-acupoints in WC and appetite(P<0.05).No serious adverse events were observed in ACE group and control group.CONCLUSIONS:Catgut embedding at acupoints and non-acupoints are all effective and safe for AO.ACE can effectively treat AO as expected and deliver lasting results.
基金the Korea Institute of Oriental Medicine(Grant No.KSN1823211 and KSN20234115)。
文摘OBJECTIVE:To assess the efficacy of acupoint catgut embedding(ACE)for simple obesity in preclinical animal experiments.METHODS:We searched the following 14 electronic databases:PubM ed,Cochrane Library,EMBASE,Oriental Medicine Advanced Searching Integrated System,KoreaMed,Korean Studies Information Service System,Science-on,Research Information Sharing Service,Korea Citation Index,Korea Traditional Knowledge Portal,China Network Knowledge Infrastructure Database,Wanfang Database,Chinese Science and Technology Journal Database,and Chinese Biology Medicine Database,from inception to November 2021 without language limitation.The assessment was performed according to the guidelines of Animal Research:Reporting of in vivo experiments;and Metaanalysis was performed using Reviewer Manager 5.4.1 software.RESULTS:Twenty-four studies involving 813 animals were selected.Meta-analysis showed that ACE was beneficial for weight control[n=40,MD=-50.63,95%CI(-57.59,-43.67),P<0.00001,I 2=0%]and reduced the Lee index[n=40,MD=-18.79,95%CI(-20.01,-17.57),P<0.00001,I 2=0%].However,when efficacy of ACE was compared with that of manual acupuncture,electroacupuncture,or oilistat therapy,statistical difference was not observed between the two groups.CONCLUSIONS:This systematic review suggests that ACE may be efficacious in treating obesity.Moreover,the analyses highlighted the necessity to perform welldesigned,higher-quality experiments.
基金Supported by Guangdong Graduate Education Innovation Program:2017SFKC13。
文摘Prof.Min LI adopted acupoint catgut embedding at Zhōngwǎn(中脘CV12),Tiānshū(天枢ST25),Wèishū(胃俞BL21),Dàchángshū(大肠俞BL25),Zúsānlǐ(足三里ST36),Sānyīnjiāo(三阴交SP6),and Tàichōng(太冲LR3),and combined with auricular plaster therapy at Wèi(胃CO4),Dacháng(大肠CO7),Gān(肝CO12),Jiāogǎn(交感AH6 a),Nèifēnmì(内分泌CO18)for the treatment of 18 cases of bulimia nervosa(BN).The result was that 9 cases were clinically cured,6 cases improved,3 case ineffective,and the total effec-tive rate was 83.33%,no obvious adverse reactions.The therapeutic effect of acupoint catgut embedding combined with auricular plaster therapy for BN is good,without side effects.
基金Passed the evaluation of science and technology achievement by the Science and Technology Bureau of Dezhou City:No.55(2008)
文摘Objective To observe the therapeutic effect of catgut embedding treatment on bilateral Zúsānlǐ(足三里ST 36) combined with Huangqi Ejiao decoction (黄芪阿胶汤) orally taken. Methods Patients with anemia due to blood loss after major operation were randomly divided into a control group and an observation group. There were 30 cases in the control group which were treated by blood transfusion and 32 cases in the observation group which were treated by catgut embedding on bilateral Zúsānlǐ (足三里ST 36) after local anesthesia combined with oral administration of self-made Huangqi Ejiao decoction (黄芪阿胶汤). The herbs included Huangqi (黄芪Radix Scutellariae Milk Veteh)10 g, Ejiao (阿胶Colla Corii Asini Donkey-hide Gelatin)10 g, Danggui (当归 Radix Angelicae Sinensin Chinese Angelica)10 g, Baizhu (白术 Radix A tractyloes Macrocephalae Large-headed Atractylodes) 10 g, Dangshen ( 党参 Radix Codonopsis Dangshen)20 g, Danshen (丹参 Salvia Miltiorrhiza Root of Red Rooted Salvia) 10 g, Honghua ( 红花 Carthamus Tinctorious Safflower) 10 g, Shudi (熟地 Rehmannia Glutinosa Prepared Rhizome of Rehmannia) 20 g, etc. After 1 d, 3 d, 7 d, 15 d, 21 d, RBC, Hb, IgM, IgG were tested. Results In the control group, Hb and RBC count immediately went up in the beginning, that peaked on the 7^th day and kept gently after. While in the observation group, there was a minimal increase in Hb and RBC in the beginning, followed by a sharp increase during 15-21 d, and peaked on the 21^th day. There was a significant difference between the observation group and the control group(P〈0.05). While, the level of IgM, IgG rose markedly in the observation group, with a significant difference between the two groups (P〈O. 01). Conclusion Catgut embedding treatment on bilateral Zúsānlǐ (足三里 ST 36) combined with oral administration of Huangqi Ejiao decoction (黄芪阿胶汤) can improve anemia due to blood loss after operation, and likewise increase the level of IgM and IgG.
基金Project of Xi’an Health Planning and Family Planning Commission(J201901001)Fundamental specialty of Shaanxi Provincial Administration of traditional Chinese medicine(Shi Wei Ji Fa[2018]No.27)+1 种基金Natural Science Foundation of Shanxi Province of of China(2020JM-696)Xi’an Fang’s Scalp Acupuncture School Inheritance Studio Project{Shi Wei Ji Han[2018]No.699}。
文摘Obesity type 2 diabetes mellitus is a common metabolic disease in clinical practice,and its prevalence is increasing rapidly with the aging of the population and changes in lifestyle.Acupuncture,as a distinctive therapy,has its unique advantages in the treatment of obesity type 2 diabetes and has an irreplaceable role in a variety of treatment methods.The author organized the literature on acupuncture and its related therapies to prevent and treat obesity type 2 diabetes in recent years and found that acupuncture and its associated therapies to prevent and treat obesity type 2 diabetes mainly include:simple acupuncture,electroacupuncture,acupoint catgut embedding therapy,auricular-plaster therapy and other treatments,all of which can safely and effectively improve clinical symptoms,acupuncture and its related therapies to treat obesity type 2 diabetes has a broad prospect,worthy of further clinical promotion.