The determination of the link with the smallest end-to-end network latency in ethernet architecture

Ethernet fundamental and its data transmission model are introduced in brief and end-to-end network latency was analyzed in this paper. On the premise of not considering transmission quality and transmission cost, latency was the function of the rest of network resource parameter (NRP). The relation between the number of nodes and that of end-to-end links was presented. In ethernet architecture, the algorithm to determine the link with the smallest latency is a polynomial issue when the number of network nodes is limited, so it can be solved by way of polynomial equations. Latency measuring is the key issue to determine the link with the smallest network latency. 3-node brigade (regiment) level network centric warfare (NCW) demonstration platform was studied and the latency between the detectors and weapon control stations was taken as an example. The algorithm of end-to-end network latency and link information in NCW was presented. The algorithm program based on Server/Client architecture was developed. The data transmission optimal link is one whose end-to-end latency is the smallest. This paper solves the key issue to determine the link whose end-to-end latency is the smallest in ethernet architecture. The study can be widely applied to determine the optimal link which is in the complex network environment of multiple service provision points.

An End-To-End Hyperbolic Deep Graph Convolutional Neural Network Framework

Graph Convolutional Neural Networks(GCNs)have been widely used in various fields due to their powerful capabilities in processing graph-structured data.However,GCNs encounter significant challenges when applied to scale-free graphs with power-law distributions,resulting in substantial distortions.Moreover,most of the existing GCN models are shallow structures,which restricts their ability to capture dependencies among distant nodes and more refined high-order node features in scale-free graphs with hierarchical structures.To more broadly and precisely apply GCNs to real-world graphs exhibiting scale-free or hierarchical structures and utilize multi-level aggregation of GCNs for capturing high-level information in local representations,we propose the Hyperbolic Deep Graph Convolutional Neural Network(HDGCNN),an end-to-end deep graph representation learning framework that can map scale-free graphs from Euclidean space to hyperbolic space.In HDGCNN,we define the fundamental operations of deep graph convolutional neural networks in hyperbolic space.Additionally,we introduce a hyperbolic feature transformation method based on identity mapping and a dense connection scheme based on a novel non-local message passing framework.In addition,we present a neighborhood aggregation method that combines initial structural featureswith hyperbolic attention coefficients.Through the above methods,HDGCNN effectively leverages both the structural features and node features of graph data,enabling enhanced exploration of non-local structural features and more refined node features in scale-free or hierarchical graphs.Experimental results demonstrate that HDGCNN achieves remarkable performance improvements over state-ofthe-art GCNs in node classification and link prediction tasks,even when utilizing low-dimensional embedding representations.Furthermore,when compared to shallow hyperbolic graph convolutional neural network models,HDGCNN exhibits notable advantages and performance enhancements.

Resting-state brain network remodeling after different nerve reconstruction surgeries:a functional magnetic resonance imaging study in brachial plexus injury rats

Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected limb.However,differences among reconstruction strategies at the brain network level have not been elucidated.This study aimed to explore intranetwork changes related to altered peripheral neural pathways after different nerve reconstruction surgeries,including nerve repair,endto-end nerve transfer,and end-to-side nerve transfer.Sprague–Dawley rats underwent complete left brachial plexus transection and were divided into four equal groups of eight:no nerve repair,grafted nerve repair,phrenic nerve end-to-end transfer,and end-to-side transfer with a graft sutured to the anterior upper trunk.Resting-state brain functional magnetic resonance imaging was obtained 7 months after surgery.The independent component analysis algorithm was utilized to identify group-level network components of interest and extract resting-state functional connectivity values of each voxel within the component.Alterations in intra-network resting-state functional connectivity were compared among the groups.Target muscle reinnervation was assessed by behavioral observation(elbow flexion)and electromyography.The results showed that alterations in the sensorimotor and interoception networks were mostly related to changes in the peripheral neural pathway.Nerve repair was related to enhanced connectivity within the sensorimotor network,while end-to-side nerve transfer might be more beneficial for restoring control over the affected limb by the original motor representation.The thalamic-cortical pathway was enhanced within the interoception network after nerve repair and end-to-end nerve transfer.Brain areas related to cognition and emotion were enhanced after end-to-side nerve transfer.Our study revealed important brain networks related to different nerve reconstructions.These networks may be potential targets for enhancing motor recovery.

Application of virtual reality technology improves the functionality of brain networks in individuals experiencing pain

Medical procedures are inherently invasive and carry the risk of inducing pain to the mind and body.Recently,efforts have been made to alleviate the discomfort associated with invasive medical procedures through the use of virtual reality(VR)technology.VR has been demonstrated to be an effective treatment for pain associated with medical procedures,as well as for chronic pain conditions for which no effective treatment has been established.The precise mechanism by which the diversion from reality facilitated by VR contributes to the diminution of pain and anxiety has yet to be elucidated.However,the provision of positive images through VR-based visual stimulation may enhance the functionality of brain networks.The salience network is diminished,while the default mode network is enhanced.Additionally,the medial prefrontal cortex may establish a stronger connection with the default mode network,which could result in a reduction of pain and anxiety.Further research into the potential of VR technology to alleviate pain could lead to a reduction in the number of individuals who overdose on painkillers and contribute to positive change in the medical field.

Unlocking the future:Mitochondrial genes and neural networks in predicting ovarian cancer prognosis and immunotherapy response

BACKGROUND Mitochondrial genes are involved in tumor metabolism in ovarian cancer(OC)and affect immune cell infiltration and treatment responses.AIM To predict prognosis and immunotherapy response in patients diagnosed with OC using mitochondrial genes and neural networks.METHODS Prognosis,immunotherapy efficacy,and next-generation sequencing data of patients with OC were downloaded from The Cancer Genome Atlas and Gene Expression Omnibus.Mitochondrial genes were sourced from the MitoCarta3.0 database.The discovery cohort for model construction was created from 70% of the patients,whereas the remaining 30% constituted the validation cohort.Using the expression of mitochondrial genes as the predictor variable and based on neural network algorithm,the overall survival time and immunotherapy efficacy(complete or partial response)of patients were predicted.RESULTS In total,375 patients with OC were included to construct the prognostic model,and 26 patients were included to construct the immune efficacy model.The average area under the receiver operating characteristic curve of the prognostic model was 0.7268[95% confidence interval(CI):0.7258-0.7278]in the discovery cohort and 0.6475(95%CI:0.6466-0.6484)in the validation cohort.The average area under the receiver operating characteristic curve of the immunotherapy efficacy model was 0.9444(95%CI:0.8333-1.0000)in the discovery cohort and 0.9167(95%CI:0.6667-1.0000)in the validation cohort.CONCLUSION The application of mitochondrial genes and neural networks has the potential to predict prognosis and immunotherapy response in patients with OC,providing valuable insights into personalized treatment strategies.

A digital twin network solution for end-to-end network service level agreement (SLA) assurance [version 1;peer review: awaiting peer review]

With the gradual development of the 5G industry network and applications,each industry application has various network performance requirements,while customers hope to upgrade their industrial structures by leveraging 5G technologies.The guarantee of service level agreement(SLA)requirements is becoming more and more important,especially SLA performance indicators,such as delay,jitter,bandwidth,etc.For network operators to fulfill customer’s requirements,emerging network technologies such as time-sensitive networking(TSN),edge computing(EC)and network slicing are introduced into the mobile network to improve network performance,which increase the complexity of the network operation and maintenance(O&M),as well as the network cost.As a result,operators urgently need new solutions to achieve low-cost and high-efficiency network SLA management.In this paper,a digital twin network(DTN)solution is innovatively proposed to achieve the mapping and full lifecycle management of the end-to-end physical network.All the network operation policies such as configuration and modification can be generated and verified inside the digital twin network first to make sure that the SLA requirements can be fulfilled without affecting the related network environment and the performance of the other network services,making network operation and maintenance more effective and accurate.

Generating Questions Based on Semi-Automated and End-to-End Neural Network

With the emergence of large-scale knowledge base,how to use triple information to generate natural questions is a key technology in question answering systems.The traditional way of generating questions require a lot of manual intervention and produce lots of noise.To solve these problems,we propose a joint model based on semi-automated model and End-to-End neural network to automatically generate questions.The semi-automated model can generate question templates and real questions combining the knowledge base and center graph.The End-to-End neural network directly sends the knowledge base and real questions to BiLSTM network.Meanwhile,the attention mechanism is utilized in the decoding layer,which makes the triples and generated questions more relevant.Finally,the experimental results on SimpleQuestions demonstrate the effectiveness of the proposed approach.

Partially Overlapped Channels- and Flow-Based End-to-End Channel Assignment for Multi-Radio Multi-Channel Wireless Mesh Networks

Capacity reduction is a major problem faced by wireless mesh networks. An efficient way to alleviate this problem is proper channel assignment. Current end-toend channel assignment schemes usually focus on the case where channels in distinct frequency bands are assigned to mesh access and backbone, but actually backbone network and access network can use the same IEEE 802.11 technology. Besides, these channel assignment schemes only utilize orthogonal channels to perform channel assignment, and the resulting network interference dramatically degrades network performance. Moreover, Internet-oriented traffic is considered only, and peerto-peer traffic is omitted, or vice versa. The traffic type does not match the practical network. In this paper, we explore how to exploit partially overlapped channels to perform endto-end channel assignment in order to achieve effective end-to-end flow transmissions. The proposed flow-based end-to-end channel assignment schemes can conquer the limitations aforementioned. Simulations reveal that loadaware channel assignment can be applied to networks with stable traffic load, and it can achieve near-optimal performance; Traffic-irrelevant channel assignment is suitable for networks with frequent change of traffic load,and it can achieve good balance between performance and overhead. Also, partially overlapped channels' capability of improving network performance is situation-dependent, they should be used carefully.

End-to-End Latency Evaluation of the Sat5G Network Based on Stochastic Network Calculus

Simultaneous use of heterogeneous radio access technologies to increase the performance of real-time,reliability and capacity is an inherent feature of satellite-5G integrated network(Sat5G).However,there is still a lack of theoretical characterization of whether the network can satisfy the end-to-end transmission performance for latency-sensitive service.To this end,we build a tandem model considering the connection relationship between the various components in Sat5G network architecture,and give an end-to-end latency calculation function based on this model.By introducing stochastic network calculus,we derive the relationship between the end-to-end latency bound and the violation probability considering the traffic characteristics of multimedia.Numerical results demonstrate the impact of different burst states and different service rates on this relationship,which means the higher the burst of arrival traffic and the higher the average rate of arrival traffic,the greater the probability of end-to-end latency violation.The results will provide valuable guidelines for the traffic control and cache management in Sat5G network.

Tibetan Multi-Dialect Speech Recognition Using Latent Regression Bayesian Network and End-To-End Mode

We proposed a method using latent regression Bayesian network (LRBN) toextract the shared speech feature for the input of end-to-end speech recognition model.The structure of LRBN is compact and its parameter learning is fast. Compared withConvolutional Neural Network, it has a simpler and understood structure and lessparameters to learn. Experimental results show that the advantage of hybridLRBN/Bidirectional Long Short-Term Memory-Connectionist Temporal Classificationarchitecture for Tibetan multi-dialect speech recognition, and demonstrate the LRBN ishelpful to differentiate among multiple language speech sets.

DTHN: Dual-Transformer Head End-to-End Person Search Network

Person search mainly consists of two submissions,namely Person Detection and Person Re-identification(reID).Existing approaches are primarily based on Faster R-CNN and Convolutional Neural Network(CNN)(e.g.,ResNet).While these structures may detect high-quality bounding boxes,they seem to degrade the performance of re-ID.To address this issue,this paper proposes a Dual-Transformer Head Network(DTHN)for end-to-end person search,which contains two independent Transformer heads,a box head for detecting the bounding box and extracting efficient bounding box feature,and a re-ID head for capturing high-quality re-ID features for the re-ID task.Specifically,after the image goes through the ResNet backbone network to extract features,the Region Proposal Network(RPN)proposes possible bounding boxes.The box head then extracts more efficient features within these bounding boxes for detection.Following this,the re-ID head computes the occluded attention of the features in these bounding boxes and distinguishes them from other persons or backgrounds.Extensive experiments on two widely used benchmark datasets,CUHK-SYSU and PRW,achieve state-of-the-art performance levels,94.9 mAP and 95.3 top-1 scores on the CUHK-SYSU dataset,and 51.6 mAP and 87.6 top-1 scores on the PRW dataset,which demonstrates the advantages of this paper’s approach.The efficiency comparison also shows our method is highly efficient in both time and space.

SDN Orchestration for Dynamic End-to-End Control of Data Center Multi-Domain Optical Networking

New and emerging use cases, such as the interconnection of geographically distributed data centers(DCs), are drawing attention to the requirement for dynamic end-to-end service provisioning, spanning multiple and heterogeneous optical network domains. This heterogeneity is, not only due to the diverse data transmission and switching technologies, but also due to the different options of control plane techniques. In light of this, the problem of heterogeneous control plane interworking needs to be solved, and in particular, the solution must address the specific issues of multi-domain networks, such as limited domain topology visibility, given the scalability and confidentiality constraints. In this article, some of the recent activities regarding the Software-Defined Networking(SDN) orchestration are reviewed to address such a multi-domain control plane interworking problem. Specifically, three different models, including the single SDN controller model, multiple SDN controllers in mesh, and multiple SDN controllers in a hierarchical setting, are presented for the DC interconnection network with multiple SDN/Open Flow domains or multiple Open Flow/Generalized Multi-Protocol Label Switching( GMPLS) heterogeneous domains. I n addition, two concrete implementations of the orchestration architectures are detailed, showing the overall feasibility and procedures of SDN orchestration for the end-to-endservice provisioning in multi-domain data center optical networks.

Attention-based neural network for end-to-end music separation

The end-to-end separation algorithm with superior performance in the field of speech separation has not been effectively used in music separation.Moreover,since music signals are often dual channel data with a high sampling rate,how to model longsequence data and make rational use of the relevant information between channels is also an urgent problem to be solved.In order to solve the above problems,the performance of the end-to-end music separation algorithm is enhanced by improving the network structure.Our main contributions include the following:(1)A more reasonable densely connected U-Net is designed to capture the long-term characteristics of music,such as main melody,tone and so on.(2)On this basis,the multi-head attention and dualpath transformer are introduced in the separation module.Channel attention units are applied recursively on the feature map of each layer of the network,enabling the network to perform long-sequence separation.Experimental results show that after the introduction of the channel attention,the performance of the proposed algorithm has a stable improvement compared with the baseline system.On the MUSDB18 dataset,the average score of the separated audio exceeds that of the current best-performing music separation algorithm based on the time-frequency domain(T-F domain).

End-to-End Performance Evaluation of TCP Traffic under Multi-Queuing Networks

While Internet traffic is currently dominated by elastic data transfers, it is anticipated that streaming applications will rapidly develop and contribute a significant amount of traffic in the near future. Therefore, it is essential to understand and capture the relation between streaming and elastic traffic behavior. In this paper, we focus on developing simple yet effective approximations to capture this relationship. We study, then, an analytical model to evaluate the end-to-end performance of elastic traffic under multi-queuing system. This model is based on the fluid flow approximation. We assume that network architecture gives the head of priority to real time traffic and shares the remaining capacity between the elastic ongoing flows according to a specific weight.

Pluggable multitask diffractive neural networks based on cascaded metasurfaces

Optical neural networks have significant advantages in terms of power consumption,parallelism,and high computing speed,which has intrigued extensive attention in both academic and engineering communities.It has been considered as one of the powerful tools in promoting the fields of imaging processing and object recognition.However,the existing optical system architecture cannot be reconstructed to the realization of multi-functional artificial intelligence systems simultaneously.To push the development of this issue,we propose the pluggable diffractive neural networks(P-DNN),a general paradigm resorting to the cascaded metasurfaces,which can be applied to recognize various tasks by switching internal plug-ins.As the proof-of-principle,the recognition functions of six types of handwritten digits and six types of fashions are numerical simulated and experimental demonstrated at near-infrared regimes.Encouragingly,the proposed paradigm not only improves the flexibility of the optical neural networks but paves the new route for achieving high-speed,low-power and versatile artificial intelligence systems.

A statistical end-to-end performance model for networks with complex topologies

Network calculus provides new tools for performance analysis of networks, but analyzing networks with complex topologies is a challenging research issue using statistical network calculus. A service model is proposed to characterize a service process of network with complex topologies. To obtain closed-form expression of statistical end-to-end performance bounds for a wide range of traffic source models, the traffic model and service model are expanded according to error function. Based on the proposed models, the explicit end-to-end delay bound of Fractional Brownian Motion（FBM） traffic is derived, the factors that affect the delay bound are analyzed, and a comparison between theoretical and simulation results is performed. The results illustrate that the proposed models not only fit the network behaviors well, but also facilitate the network performance analysis.

Screening biomarkers for spinal cord injury using weighted gene co-expression network analysis and machine learning

Immune changes and inflammatory responses have been identified as central events in the pathological process of spinal co rd injury.They can greatly affect nerve regeneration and functional recovery.However,there is still limited understanding of the peripheral immune inflammato ry response in spinal cord inju ry.In this study.we obtained microRNA expression profiles from the peripheral blood of patients with spinal co rd injury using high-throughput sequencing.We also obtained the mRNA expression profile of spinal cord injury patients from the Gene Expression Omnibus(GEO)database(GSE151371).We identified 54 differentially expressed microRNAs and 1656 diffe rentially expressed genes using bioinformatics approaches.Functional enrichment analysis revealed that various common immune and inflammation-related signaling pathways,such as neutrophil extracellular trap formation pathway,T cell receptor signaling pathway,and nuclear factor-κB signal pathway,we re abnormally activated or inhibited in spinal cord inju ry patient samples.We applied an integrated strategy that combines weighted gene co-expression network analysis,LASSO logistic regression,and SVM-RFE algorithm and identified three biomarke rs associated with spinal cord injury:ANO10,BST1,and ZFP36L2.We verified the expression levels and diagnostic perfo rmance of these three genes in the original training dataset and clinical samples through the receiver operating characteristic curve.Quantitative polymerase chain reaction results showed that ANO20 and BST1 mRNA levels were increased and ZFP36L2 mRNA was decreased in the peripheral blood of spinal cord injury patients.We also constructed a small RNA-mRNA interaction network using Cytoscape.Additionally,we evaluated the proportion of 22 types of immune cells in the peripheral blood of spinal co rd injury patients using the CIBERSORT tool.The proportions of naive B cells,plasma cells,monocytes,and neutrophils were increased while the proportions of memory B cells,CD8^(+)T cells,resting natural killer cells,resting dendritic cells,and eosinophils were markedly decreased in spinal cord injury patients increased compared with healthy subjects,and ANO10,BST1 and ZFP26L2we re closely related to the proportion of certain immune cell types.The findings from this study provide new directions for the development of treatment strategies related to immune inflammation in spinal co rd inju ry and suggest that ANO10,BST2,and ZFP36L2 are potential biomarkers for spinal cord injury.The study was registe red in the Chinese Clinical Trial Registry(registration No.ChiCTR2200066985,December 12,2022).

Social-ecological perspective on the suicidal behaviour factors of early adolescents in China:a network analysis

Background In early adolescence,youth are highly prone to suicidal behaviours.Identifying modifiable risk factors during this critical phase is a priority to inform effective suicide prevention strategies.Aims To explore the risk and protective factors of suicidal behaviours(ie,suicidal ideation,plans and attempts)in early adolescence in China using a social-ecological perspective.Methods Using data from the cross-sectional project‘Healthy and Risky Behaviours Among Middle School Students in Anhui Province,China',stratified random cluster sampling was used to select 5724 middle school students who had completed self-report questionnaires in November 2020.Network analysis was employed to examine the correlates of suicidal ideation,plans and attempts at four levels,namely individual(sex,academic performance,serious physical llness/disability,history of self-harm,depression,impulsivity,sleep problems,resilience),family(family economic status,relationship with mother,relationship with father,family violence,childhood abuse,parental mental illness),school(relationship with teachers,relationship with classmates,school-bullying victimisation and perpetration)and social(social support,satisfaction with society).Results In total,37.9%,19.0%and 5.5%of the students reported suicidal ideation,plans and attempts in the past 6 months,respectively.The estimated network revealed that suicidal ideation,plans and attempts were collectively associated with a history of self-harm,sleep problems,childhood abuse,school bullying and victimisation.Centrality analysis indicated that the most influential nodes in the network were history of self-harm and childhood abuse.Notably,the network also showed unique correlates of suicidal ideation(sex,weight=0.60;impulsivity,weight=0.24;family violence,weight=0.17;relationship with teachers,weight=-0.03;school-bullying perpetration,weight=0.22),suicidal plans(social support,weight=-0.15)and suicidal attempts(relationship with mother,weight=-0.10;parental mental llness,weight=0.61).Conclusions This study identified the correlates of suicidal ideation,plans and attempts,and provided practical implications for suicide prevention for young adolescents in China.Firstly,this study highlighted the importance of joint interventions across multiple departments.Secondly,the common risk factors of suicidal ideation,plans and attempts were elucidated.Thirdly,this study proposed target interventions to address the unique influencing factors of suicidal ideation,plans and attempts.

End-to-End Auto-Encoder System for Deep Residual Shrinkage Network for AWGN Channels

With the rapid development of deep learning methods, the data-driven approach has shown powerful advantages over the model-driven one. In this paper, we propose an end-to-end autoencoder communication system based on Deep Residual Shrinkage Networks (DRSNs), where neural networks (DNNs) are used to implement the coding, decoding, modulation and demodulation functions of the communication system. Our proposed autoencoder communication system can better reduce the signal noise by adding an “attention mechanism” and “soft thresholding” modules and has better performance at various signal-to-noise ratios (SNR). Also, we have shown through comparative experiments that the system can operate at moderate block lengths and support different throughputs. It has been shown to work efficiently in the AWGN channel. Simulation results show that our model has a higher Bit-Error-Rate (BER) gain and greatly improved decoding performance compared to conventional modulation and classical autoencoder systems at various signal-to-noise ratios.

Adjusting Sink Location to Reduce End-to-End Delay in Low-Duty-Cycle Wireless Sensor Networks

Low-duty-cycle mechanisms can reduce the energy consumption significantly in wireless sensor networks（WSNs）. Sensors stay dormant most of the time to save their energy and wake up based on their needs. However, such a technique, while prolonging the network lifetime, sets excessive challenges for reducing the end-to-end（E2E） delay within the network. In this paper, the centralized cluster-based location finding（CCLF） algorithm is proposed to reduce the high latency in low-duty-cycle WSNs by finding a suitable position for the sink. The algorithm is mainly composed of three steps： a） the cluster construction, b） the fast look-up table（FLU-table） construction, and c） the sink location decision. The simulation results show that the performance of the CCLF algorithm is significantly similar to that of the optimal algorithm. Moreover, the CCLF algorithm requires less operation time compared with the optimal algorithm.