THE SOURCE OF ENDOGENOUS DIGITALIS-LIKE SUBSTANCE IN NORMAL PREGNANCY

There are increasing evidences for the presence of an endogenous digitalis-like substance (EDLS) which interacts with the digitalis receptor and acts against the digoxin serum response in human body. The plasma EDLS level increases in response to fluid or salt loading. EDLS may play a role in salt and blood pressure regulation. Being considered as a volume-expanding state, pregnancy may cause an increase in maternal EDLS. However, further studies to identify the origin of EDLS in normal pregnancy are needed.

急性脑血管病患者内源性类洋地黄物质的测定及其临床意义

本文测定了100例急性脑血管病患者血清和脑脊液内源性类洋地黄物质(EDLS)浓度,并作动态观察。结果血清和脑脊液中EDLS含量均明显高于对照组,并受病情轻重、意识水平和出血部位影响;和血糖水平呈正相关;治疗后随病情好转降至正常。表明EDLS测定有助于病情估计、预后判断及疗效观察。