Laboratory diagnosis of infectious endophthalmitis

AIM:To analyze the lab diagnosis and etiology of infectious endophthalmitis.METHODS:The medical and microbial records of 36 patients diagnosed with infectious endophthalmitis and 8 patients diagnosed with intraocular lens(IOL)-related inflammation between Nov.1999 and Dec.2009 were retrospectively reviewed for lab diagnosis and etiology.RESULTS:The inflammatory cell counts in all aqueous humor specimens from infectious endophthalmitis patients were more than in all aqueous humor specimens from patients with IOL-related inflammation.Sixteen of the 36 aqueous humor samples(44.4%) and 11 of the 24 vitreous humor samples(45.8%) from infectious endophthalmitis patients showed positive results in smears;while 17 aqueous humor samples(47.2%) and 15 vitreous humor samples(62.5%) from infectious endophthalmitis patients showed positive results in culture.CONCLUSION:The inflammatory cell count may be an important index for infectious endophthalmitis;while,smears can show etiological information earlier.

Evaluation on application effect of psychological nursing intervention on patients with traumatic endophthalmitis

Background:To explore the application effect of psychological nursing intervention in patients with traumatic endophthalmitis.Methods:A total of 90 patients with traumatic endophthalmitis admitted to our hospital from August 2018 to April 2019 were selected as study objects and randomly divided into observation group and control group,with 45 cases in each group.The control group received routine nursing care,and the observation group performed psychological nursing intervention on the basis of the control group.The scores of self-rating anxiety scale(SAS)and self-rating depression scale(SDS)and nursing satisfaction degree were compared before and after nursing treatment in two groups.Results:The scores of SAS and SDS of the observation group were better than those of the control group.The score of the nursing satisfaction degree of the observation group was higher than that of the control group,showing statistically significant difference(P<0.05).Conclusions:Psychological nursing intervention can improve the physical and mental condition of patients with traumatic endophthalmitis,reduce their negative emotions such as anxiety and depression,and improve the satisfaction of nursing.It is worthy of clinical promotion.

Traumatic endophthalmitis and the outcome after vitrectomy in young children

AIM:To explore the traumatic endophthalmitis in young children and the outcome of pars plana vitrectomy(PPV).METHODS:Twenty-two eyes of 22 cases of young children consecutive pediatric traumatic endophthalmitis treated and followed up between September 2014 and May 2018 were included.Aqueous humor or vitreous samples were taken for bacterial culture and sensitivity tests.Intravitreal antibiotics(norvancomycin and ceftazidime)injection,combined with 23-gauge PPV,were administered in 22 eyes.Silicone oil(SO;5000 centistoke)tamponade or perfluoropropane gas(C3F8)was used in all patients.Main outcome measures were best-corrected visual acuity(BCVA)and retinal attachment,the ratio of penetrating injury,and the existence of intraocular foreign body.RESULTS:The mean age of patients was 6.9±2.2(range,3-10)y.All injured eyes suffered from penetrating ocular injury with retained intraocular foreign body in one eye.Bacterial culture was positive in only 2 eyes.The mean follow-up time was 21.1±4.7(range,12-30)mo.In the primary PPV,intravitreal antibiotics was administrated in all eyes,SO in 18 eyes,and C3F8 in 4 eyes.The secondary operation of SO removal and C3F8 endotamponade was performed in 16 eyes and a second SO endotamponade due to emulsification of the oil and retinal detachment(RD)was operated in 7 eyes underwent 3 to 11.5 mo after primary PPV.A third operation was done in 7 eyes.The final intraocular pressure(IOP)was 8.9±1.8(range,6.9-11.4)mm Hg.The final BCVAs were 20/200 or better in 5,counting fingers in 2,and light perception to hand movement in 8 eyes.Whose(66.7%)had retinal injury exhibited worse BCVA(P=0.019,Fisher’s exact test).Eyes underwent SO tamponade exhibited worse final BCVA than that with C3F8 in the primary PPV(P=0.026,Fisher’s exact test).CONCLUSION:Traumatic endophthalmitis in children is generally more severe and associated with more complicated surgical procedures.Most patients have retinal injury need multiple operations and the final BCVA is poor.Prevention of ocular trauma,especially in children,is still critical.

Endogenous Endophthalmitis as a Triggering Factor for Fatal Bacterial Meningitis Caused by Streptococcus pneumoniae: A Case Report

Endogenous endophthalmitis is a rare condition with a poor long-term visual prognosis and significant mortality, often associated with the hematogenous spread of intravitreal infections and subsequent disruption of the blood-ocular barrier. Its anatomical proximity to the central nervous system (CNS) poses a high risk of infection dissemination, although cases documented in the literature are rare, and endogenous endophthalmitis is typically described as secondary to neuroinfections. We report the case of an 82-year-old female patient with a history of hypertension who presented with fever, decreased visual acuity, severe headache, chemosis, and conjunctival injection. Endogenous endophthalmitis was diagnosed, and antimicrobial treatment was initiated alongside surgical intervention by the ophthalmology service. However, the patient’s condition worsened neurologically, and Streptococcus pneumoniae was identified in cerebrospinal fluid cultures. Despite intensive medical treatment, the patient’s clinical course was poor, leading to death.

Non-infectious endophthalmitis after vitrectomy

Background Non-infectious endophthalmitis was reported to occur after cataract surgery or intravitreal injections. This study reported a series of patients having non-infectious endophthalmitis after pars plana vitrectomy in the same two operation rooms during the same period to estimate the risk factors for non-infectious endophthalmitis after vitrectomy. Methods Medical records of patients who presented with severe non-infectious endophthalmitis following vitrectomy between May 13 and June 8, 2011, were reviewed. The presenting symptoms and signs were collected, including visual acuity, intraocular pressure, cornea and anterior chamber activity. The treatments and results of microbiology examination were also recorded and analyzed. Results Ten patients were identified with severe non-infectious endophthalmitis, presenting 1 day after pars plana vitrectomy. Three eyes （30%） had previous intraocular surgeries, four （40%） had proliferative diabetic retinopathy, and one （10%） got pars plana vitrectomy combinded with phacoemulsification and intraocular lens implantation. All the patients were initially treated with topical and/or oral steroids. Only two patients had intravenous antibiotics because of the atypical presentation. One eye had paracentesis because of high intraocular pressure and the aqueous sample was sent for microbiological examination. The culture of the aqueous, air in the operation room, the swab from hand of surgeons, infusion fluid, and vitrectomy effluent were all negative for bacteria and fungi. The inflammation regressed rapidly after the initial treatment. Conclusions Intraocular surgery history, poor general health status, longer operation time, and more surgical procedures are the risk factors for non-infectious endophthalmitis after vitrectomy. It responds well to steroids.

白内障超声乳化术后感染性眼内炎的炎症指标变化及危险因素分析

目的探讨白内障患者超声乳化术后感染性眼内炎的炎症指标变化及其危险因素。方法选择2022年1月至2023年12月郑州市第二人民医院收治的126例白内障超声乳化手术患者作为观察组,将20例术后发生感染性眼内炎者作为感染组,106例未发生感染性眼内炎者作为未感染组,选取同期在本院体检的100例健康人群作为对照组。术后第3天清晨,比较两组受检者血清高敏C反应蛋白(hs-CRP)、血清淀粉样蛋白A(SAA)、降钙素原(PCT)、白细胞介素-1β(IL-1β)水平,并比较感染组和未感染组患者的一般临床资料(年龄、性别、吸烟、饮酒、糖尿病、高血压)、术中情况(手术切口位置、手术时间、术中出血量)和血清hs-CRP、SAA、PCT、IL-1β水平。采用Logistic回归分析影响白内障超声乳化术后感染性眼内炎的危险因素。结果观察组患者的血清hs-CRP、SAA、PCT、IL-1β水平分别为(21.49±3.01)mg/L、(15.28±2.63)mg/L、(2.12±0.80)ng/L、(23.11±5.70)ng/L,明显高于对照组的(6.15±1.20)mg/L、(6.45±1.09)mg/L、(0.40±0.05)ng/L、(17.10±4.19)ng/L,差异均有统计学意义(P<0.05);感染组患者的术中出血量、血清hs-CRP、SAA、PCT、IL-1β分别为(123.25±36.35)m L、(32.45±5.13)mg/L、(23.01±4.25)mg/L、(6.79±1.45)ng/L、(36.42±6.40)ng/L,明显高于未感染组的(108.26±22.78)m L、(10.25±1.85)mg/L、(13.43±2.54)mg/L、(0.70±0.17)ng/L、(20.93±4.35)ng/L,差异均有统计学意义(P<0.05);Logistic回归分析结果显示,术中出血量、血清hs-CRP、SAA、PCT、IL-1β均是影响白内障超声乳化术后感染性眼内炎的危险因素(P<0.05)。结论白内障超声乳化术后感染性眼内炎患者的血清hs-CRP、SAA、PCT、IL-1β水平均明显升高,且其与术中出血量均是术后眼内炎感染的危险因素,针对各危险因素制定干预措施,有助于减少感染性眼内炎发生。

耐药葡萄球菌对眼科常用抗菌药物的体外敏感性研究

目的了解外伤性眼内炎中病原菌分布特点及主要致病耐药葡萄球菌对眼科常用抗菌药物的体外敏感性。方法收集2018年7月—2023年7月于绵阳市中心医院外伤性眼内炎患者样本中检测的136株细菌,进行细菌培养、细菌鉴定和药敏试验。结果136株细菌由革兰阳性菌(n=81)、革兰阴性菌(n=49)和真菌(n=6)组成。主要感染病原菌为金黄色葡萄球菌42株、表皮葡萄球菌18株;2种耐药葡萄球菌对左氧氟沙星、头孢唑林钠、妥布霉素和夫西地酸的最小抑菌浓度(MIC)差异较小(0.7~7.5μg·mL^(-1)),对克林霉素的MIC差异较大(2.5~500μg·mL^(-1))。耐药葡萄球菌对5种抗生素的敏感性均差异无统计学意义(均P>0.05)。5种眼用抗生素对耐药葡萄球菌的敏感率差异有统计学意义(P<0.05),其中头孢唑林钠和夫西地酸对耐药葡萄球菌的敏感率显著高于克林霉素、左氧氟沙星和妥布霉素。结论耐药葡萄球菌是外伤性眼内炎患者的主要感染病原菌,夫西地酸、头孢唑林钠对耐药葡萄球菌的抗菌活性优于妥布霉素、左氧氟沙星、克林霉素。

老年白内障病人术后感染性眼内炎风险评估模型的构建与检验

目的:构建老年白内障病人术后感染性眼内炎风险评估模型,并检验模型预测能力。方法:选取我院2021年1月—2022年7月收治的老年白内障手术病人180例,根据是否发生感染性眼内炎将病人分为发生组和未发生组,采用单因素分析、多因素Logistic回归分析筛选老年白内障病人术后感染性眼内炎的危险因素,结合Logistic回归分析结果构建老年白内障病人术后感染性眼内炎风险评估模型。选取我院2022年8月—2023年4月收治的老年白内障手术病人50例校验模型预测能力。结果:180例老年白内障手术病人并发感染性眼内炎21例,发生率为11.67%;多因素Logistic回归分析结果显示,年龄>70岁、合并糖尿病、手术时间≥20 min、术中玻璃体溢出、血清清蛋白<35 g/L为老年白内障病人术后感染性眼内炎发生的危险因素(P<0.05)。Hosmer-Lemeshow检验结果显示,P>0.05,提示预测情况与实际情况比较一致,模型有较好拟合度;模型受试者工作特征曲线(ROC)下面积为0.813,95%CI(0.765,0.862),灵敏度为0.823、特异度为0.879,约登指数为0.702;外部验证结果显示,模型预测准确值为86.00%,灵敏度为87.50%,特异度为85.71%,Kappa一致性系数为0.504。结论:老年白内障病人术后感染性眼内炎发生率较高,且其危险因素复杂,研究构建的老年白内障病人术后感染性眼内炎风险评估模型有较好的预测能力。

眼科术后感染性眼内炎的回顾性分析

目的:分析不同类型眼科术后感染性眼内炎的致病菌、耐药性、治疗方法及预后。方法:回顾性分析。选取河北省人民医院眼科2009-01/2023-06收治的眼科术后感染性眼内炎患者37例37眼。分析不同类型眼科术后感染性眼内炎的致病菌、耐药性、早期玻璃体腔注射抗生素或玻璃体切除联合硅油填充术的治疗效果。结果:纳入术后感染性眼内炎患者37眼中,白内障超声乳化摘除联合人工晶状体植入术后24眼,玻璃体切除术后4眼,青光眼白内障联合术后2眼,抗青光眼术后2眼,角膜移植术后2眼,前房穿刺术后2眼,玻璃体腔注药术后1眼。眼内液标本送检37例(玻璃体+房水14例,单纯玻璃体20例,单纯房水3例),检出致病菌20株,其中革兰氏阳性菌17株(12例为表皮葡萄球菌),革兰氏阴性菌2株,真菌1株(镰刀菌)。37眼中行单纯玻璃体腔注药7眼、玻璃体腔注药联合玻璃体切除11眼、单纯玻璃体切除19眼。末次随访时,最佳矫正视力(BCVA)≤0.05者15眼,0.06-0.3者15眼,0.4-1.0者7眼,与治疗前(无光感-手动者31眼,数指-0.05者3眼,0.06-0.3者3眼)有差异(P<0.001)。结论:对于眼内感染相对较轻、初诊视力相对较好的眼科术后感染性眼内炎患者,玻璃体腔注射抗生素仍然是一种经济有效的治疗手段。早期进行玻璃体切除术可以有效控制眼科术后感染性眼内炎的进展,减少手术次数,显著提高视力。

血清标志物sTREM⁃1、AQP5对白内障术后感染性眼内炎的预测价值研究

目的研究血清标志物可溶性人髓系细胞触发受体⁃1(sTREM⁃1)和水通道蛋白5(AQP5)是对白内障术后感染性眼内炎的预测价值。方法选择2021年10月⁃2023年10月期间在成都爱尔眼科医院行手术治疗的白内障患者146例作为观察组,另取同期进行体检的健康者120名作为对照组,比较两组间血清sTREM⁃1、AQP5水平的差异;根据观察组术后是否发生白内障术后感染性眼内炎并分为感染亚组(n=31)和非感染亚组(n=115),比较两亚组间血清sTREM⁃1、AQP5水平及临床资料的差异,采用二元logistic回归分析白内障术后感染性眼内炎的影响因素,采用受试者工作特征(ROC)曲线分析血清sTREM⁃1、AQP5对白内障术后感染性眼内炎的预测价值。结果观察组患者的血清sTREM⁃1、AQP5水平高于对照组,差异有统计学意义(t=13.235、12.484,P<0.05);感染亚组患者的血清sTREM⁃1、AQP5水平以及糖尿病比例、手术时间、术中出血量、玻璃体溢出比例均高于非感染亚组,差异有统计学意义(t=6.536、4.026、4.392、6.934、10.544、14.508,P<0.05);有糖尿病史、手术时间延长及血清sTREM⁃1、AQP5水平增加是白内障术后感染性眼内炎的危险因素(P<0.05);血清sTREM⁃1、AQP5对白内障术后感染性眼内炎具有预测价值,预测的曲线下面积分别为0.807、0.905。结论血清sTREM⁃1、AQP5水平增加与白内障术后感染性眼内炎相关,两项指标均对白内障术后感染性眼内炎具有预测价值。

脑膜炎奈瑟菌致老年糖尿病患者感染性眼内炎1例

1例74岁的老年男性糖尿病患者,因右眼红肿胀痛入院,临床上通过患者右眼前房和玻璃体腔抽出液行涂片培养和宏基因组二代测序(mNGS),最终通过mNGS诊断为脑膜炎奈瑟菌引起的感染性眼内炎,经手术治疗和及时有效的抗生素治疗后,患者右眼感染明显控制,眼内炎好转出院。

Advancements in the mind-machine interface:towards re-establishment of direct cortical control of limb movement in spinal cord injury

Spinal cord injury（SCI）resulting in loss of motor function can be caused by a variety of conditions,ranging from traumatic to neoplastic to infectious.It is estimated that nearly 300,000individuals live with the effects of SCI in the United States alone（National Spinal Cord Injury Statistical Center,2016）.Current treatment modalities for patients suffering from SCI are primarily supportive,

年龄相关性白内障术后发生感染性眼内炎的病原学特点及相关因素

目的:探究年龄相关性白内障手术后发生感染性眼内炎的病原学特点及相关因素与预防。方法:回顾性分析本院2016-01/2018-01收治的1 365例年龄相关性白内障患者,统计患者感染性眼内炎发生情况,并分析感染性眼内炎病原学特点及相关危险因素。结果:患者28例发生感染性眼内炎,共检出病原菌36株,其中表皮葡萄球菌9株(25.00%),铜绿假单胞菌9株(25.00%),芽孢杆菌8株(22.22%)。铜绿假单胞菌、芽孢杆菌对头孢唑林、头孢噻肟、阿莫西林具有较强的耐药性;对头孢哌酮-舒巴坦、美罗培南的敏感性较高;表皮葡萄球菌对青霉素、红霉素、阿奇霉素有较强的耐药性,对万古霉素、呋喃妥因、米诺环素的敏感性较高。Logistic多因素回归分析,年龄(≥70岁)、糖尿病、手术时间(≥15min)、术中玻璃体溢出是年龄相关性白内障术后发生感染性眼内炎的独立危险因素(P<0.05)。结论:年龄相关性白内障手术后感染性眼内炎病原菌以表皮葡萄球菌、铜绿假单胞菌、芽孢杆菌多见。年龄(≥70岁)、糖尿病、手术时间(≥15min)、术中玻璃体溢出为年龄相关性白内障手术后发生感染性眼内炎的独立危险因素。

白内障术后眼内感染的分析及其防治

白内障术后感染性眼内炎是严重危害患者术后视力恢复的并发症之一。本文就其发病率?危险因素?治疗及预防等做一综述,为临床医生提供参考依据。

感染性眼内炎导致眼球丧失的流行病学调查

目的 探讨感染性眼内炎导致眼球丧失的相关危险因素。方法 对 1993年 2月～ 2 0 0 2年 12月收治的116例 (117眼 )感染性眼内炎患者进行回顾分析。结果 2 1例 (2 1眼 )行眼球摘除或眼内容物剜出 ,发生率为17 95 % ;其中视力无光感的眼内炎病例中眼球丧失的发生率是 80 % (P =0 .0 0 0 1OR =73.6 ) ;内源性眼内炎的发生率是 4 5 .4 5 % (P =0 .0 12 5OR =4 .6 9) ;眼球破裂伤的发生率是 4 1.6 7% (P =0 .0 0 31OR =6 .78) ;女性眼内炎的发生率是 35 .2 9% (P =0 .0 0 2OR =4 .4 8) ;前、后 5年眼球摘除或眼内容物剜出的发生率分别是 2 6 .5 3%和11 76 % (P =0 .0 4 0 )。结论 眼内炎病例中视力无光感、内源性眼内炎、眼球破裂伤及女性是导致眼球摘除或眼内容物剜出的危险因素 ;眼球摘除或眼内容物剜出的发生率逐年减少。

感染性眼内炎的致病菌培养结果分析

目的:探讨引起感染性眼内炎的致病菌对广谱抗生素的耐药性及敏感性。方法:对我院15例白内障术后眼内炎术中抽取玻璃体做病原学检查并对治疗结果进行回顾性分析。结果:此15例在术中采集前房水及玻璃体做细菌培养与药物敏感试验,7例培养出致病菌,细菌培养阳性率47%(其中真菌1例,表皮葡萄球菌3例,缓慢葡萄球菌1例,凝固酶阴性葡萄球菌1例,浅绿气球菌1例),8例示无菌生长。培养阳性病例中3例表皮葡萄球菌和1例缓慢葡萄球菌的药敏试验均显示对左氧氟沙星是耐药的,MIC均>4;另外1例凝固酶阴性葡萄球菌和1例浅绿气球菌药敏试验显示对左氧氟沙星是敏感的,MIC均<2,万古霉素与利福平均为敏感抗生素,MIC均<1。结论:大多数医疗机构常规使用左氧氟沙星作为内眼手术预防性用药,但本文章总结后对此现象提出质疑。临床医生对致病菌经验性用药经常出现,但当未做细菌培养和药物敏感性试验同时致病菌出现耐药时经验性用药往往导致治疗效果降低或更严重的后果。因此应该及时根据细菌培养和药物敏感性试验结果合理选择抗生素,适时调整用药方案是规范治疗的首选。

儿童外伤性白内障眼内炎患者人工晶状体植入时机的选择

目的:探讨儿童外伤性白内障眼内炎患者人工晶状体植入的手术时机。方法:本研究为前瞻性研究,入选病例为我院2003-06/2005-06收治的69例69眼儿童外伤性白内障眼内炎患者,术中观察玻璃体积脓不超过一个象限或仅累及前部玻璃体,视网膜状态完好者。将69例69眼患者随机分为两组,对两组患者采用不同手术方式进行治疗,A组34例34眼:进行玻璃体切除,同期植入人工晶状体;B组35例35眼:先进行玻璃体切除,术后3～6moII期植入人工晶状体。比较两种方法的治疗效果。结果:两组患者术后视力均明显提高。两组手术前后视力分别进行比较P=0.000,差别均有显著统计学意义;两组之间手术前后视力比较,术前P=0.978,差别无显著统计学意义;术后P=0.005,差别有显著统计学意义。A组患者术后视力明显好于B组。两组之间术后反应及并发症进行比较,差别无显著统计学意义。结论:在严格控制适应证的基础上,儿童外伤性白内障眼内炎患者,进行玻璃体切除同期植入人工晶状体,配合有效的术后处理,一般均能取得较好的治疗效果。

抗青光眼小梁切除术后感染性眼内炎临床分析

目的探讨小梁切除术后感染性眼内炎发生的临床特点、治疗方法和预后。方法回顾性分析1999年1月至2009年12月中山大学中山眼科中心收治,并送病理科检查的12例小梁切除术后感染性眼内炎患者的临床资料,包括患者一般情况、抗青光眼手术情况、术后感染性眼内炎治疗前后的情况及病原学检查结果。结果病理涂片检查及培养的病原体总检出率为66.7%,迟发性眼内炎者真菌检出率为22.2%。使用抗感染药物联合早期前房冲洗注药、经扁平部后段玻璃体切割术及玻璃体内注药可有效控制感染,治疗后所有患者前房积脓消失,房水闪辉阴性。44.4%的迟发性眼内炎患者治疗后视力提高,最佳矫正视力达到0.2。所有患者治疗后眼压均正常。结论对于小梁切除术后感染性眼内炎,取材行病理涂片检查可早期诊断并提高病原体的检出率,经扁平部后段玻璃体切割术是有效的治疗方法 ,其预后与发病时视力、病原体种类及其毒力有关。

外伤性枯草杆菌性眼内炎临床分析

目的：总结外伤性枯草杆菌性眼内炎的临床特征，探讨早期诊治的措施。方法：回顾性总结分析2003年1月至2013年12月中山大学中山眼科中心眼外伤科收治的枯草杆菌性眼内炎的22例（22眼）患者的临床资料。结果：22例患者，合并眼内异物存留15例，角膜浸润15例，眼眶蜂窝组织炎7例。接受伤口缝合眼内抗生素注射7例，单纯玻璃体手术7例，玻璃体手术联合硅油填充8例。11例无光感．11例光感～0．05，3例眼内容剜除。22株枯草杆菌菌株对妥布霉素、庆大霉素、头孢哌酮、左氧氟沙星及氧氟沙星敏感。年龄、角膜浸润和眼内异物存留是枯草杆菌眼内炎预后不良的危险因素（P〈0．05）．硅油填充是预后较好的保护因素（P〈0．05）。结论：以角膜伤口为中心的环状浸润，前房脓血样积液是枯草杆菌眼内炎的典型体征。庆大霉素、妥布霉素、头孢哌酮、左氧氟沙星和氧氟沙星是治疗枯草杆菌眼内炎有效抗生素，及早进行玻璃体手术联合硅油填充是挽救视功能最有效的方法。

193例感染性眼内炎患者致病原因及临床特点分析

目的对感染性眼内炎的致病原因、临床诊治及其特点进行分析,为该病的防治提供参考资料。方法对2014年1月至2017年6月诊治于南昌大学第二附属医院的193例(193眼)感染性眼内炎患者进行回顾性分析,统计患者的致病因素、病原学、治疗及预后等特点。结果所有患者中外伤性眼内炎137例(71.0%),铁器类、木制品和物体类是致病的主要原因;眼部手术后感染性眼内炎35例(18.1%),以白内障和青光眼术后为主;内源性眼内炎15例(7.8%),以不明原因的病例为主;感染性角膜炎导致者6例(3.1%)。181例患者病原菌培养阳性率为13.3%,以凝固酶阴性葡萄球菌和草绿色链球菌为主要病原菌。眼部手术后及内源性眼内炎患者合并有糖尿病和(或)高血压易感因素的比例较高,玻璃体切割术是主要的治疗方式。感染性眼内炎患者治疗前最佳矫正视力无光感~0.02者占比为86.2%,治疗后无光感~0.02者占比为62.9%、≥0.10者占比为24.9%,差异有统计学意义(P<0.001);其中治疗前后视力有统计学差异的是外伤性及眼部手术后患者,内源性眼内炎患者治疗前后视力比较无统计学差异。感染性角膜炎导致者视力大部分无光感。结论外伤性和眼部手术后眼内炎是感染性眼内炎的两种主要类型,玻璃体切割术是主要的治疗手段。感染性眼内炎经不同的方式积极治疗后可以控制感染,改善视功能。