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Endoscopic polidocanol foam sclerobanding for the treatment of grade Ⅱ-Ⅲ internal hemorrhoids:A prospective,multi-center,randomized study 被引量:3
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作者 Chun-Ying Qu Fei-Yu Zhang +10 位作者 Yi Zhang Ming-Ming Li Zheng-Hong Li Mei-Hong Cai Lei-Ming Xu Feng Shen Wen Wang Wu-Lian Lin Feng-Yu Gao Hao Zhang Guang-Yu Chen 《World Journal of Gastroenterology》 SCIE CAS 2024年第27期3326-3335,共10页
BACKGROUND Endoscopic rubber band ligation(ERBL)is a nonsurgical technique for the treatment of symptomatic internal hemorrhoids but is limited by recurrence and post-procedural pain.AIM To evaluate satisfaction,long-... BACKGROUND Endoscopic rubber band ligation(ERBL)is a nonsurgical technique for the treatment of symptomatic internal hemorrhoids but is limited by recurrence and post-procedural pain.AIM To evaluate satisfaction,long-term recurrence,and post-procedural pain in managing internal hemorrhoids using a combination of polidocanol foam sclerotherapy and ERBL.METHODS This was a prospective,multicenter,randomized study.A total of 195 consecutive patients diagnosed with grade II-III internal hemorrhoids were enrolled from four tertiary hospitals and randomly divided into a cap-assisted endoscopic polidocanol foam sclerobanding(EFSB)or an ERBL group.All patients were followed-up for 12 months.Symptom-based severity and post-procedural pain were assessed using a hemorrhoid severity score(HSS)and a visual analog scale(VAS).Continuous variables were reported as medians and interquartile range.RESULTS One hundred and ninety-five patients were enrolled,with 98 in the EFSB group.HSS was lower in the EFSB group than in the ERBL group at 8 weeks[4.0(3.0-5.0)vs 5.0(4.0-6.0),P=0.003]and 12-month[2.0(1.0-3.0)vs 3.0(2.0-3.0),P<0.001]of follow-up.The prolapse recurrence rate was lower in the EFSB group at 12 months(11.2%vs 21.6%,P=0.038).Multiple linear regression analysis demonstrated that EFSB treatment[B=-0.915,95%confidence interval(CI):−1.301 to−0.530,P=0.001]and rubber band number(B=0.843,95%CI:0.595-1.092,P<0.001)were negatively and independently associated with the VAS score 24 hours post-procedure.The median VAS was lower in the EFSB group than in the ERBL[2.0(1.0-3.0)vs 3.0(2.0-4.0),P<0.001].CONCLUSION Cap-assisted EFSB provided long-term satisfaction and effective relief from the recurrence of prolapse and pain 24 hours post-procedure. 展开更多
关键词 Internal hemorrhoids endoscopic therapy Polidocanol foam SCLEROTHERAPY rubber band ligation Sclerobanding
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Endoscopic polidocanol foam sclerobanding for the treatment of Grade Ⅱ-Ⅲ internal hemorrhoids:The focus of clinical practice
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作者 Yu-Yan Zhang Bing Hu 《World Journal of Gastroenterology》 SCIE CAS 2024年第38期4246-4248,共3页
We have read the article by Qu et al with great interest,as it presents an inte-gration of endoscopic polidocanol foam sclerotherapy with rubber band ligation in patients with Grade Ⅱ-Ⅲ internal hemorrhoids.The auth... We have read the article by Qu et al with great interest,as it presents an inte-gration of endoscopic polidocanol foam sclerotherapy with rubber band ligation in patients with Grade Ⅱ-Ⅲ internal hemorrhoids.The authors conducted a prospective,multicenter,randomized study to evaluate the long-term sympto-matic and endoscopic efficacy of this combined intervention.In this discussion,we focus on the procedural steps of this combined strategy and suggest potential avenues for future research. 展开更多
关键词 Internal hemorrhoids endoscopic therapy Polidocanol foam SCLEROTHERAPY rubber band ligation Sclerobanding
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Endoscopic polidocanol foam sclerobanding for treatment of internal hemorrhoids:A novel outpatient procedure
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作者 An-Na Mou Yu-Ting Wang 《World Journal of Gastroenterology》 SCIE CAS 2024年第42期4583-4586,共4页
In the study,we comment on the article by Qu et al.Internal hemorrhoids are the most common anorectal disorders worldwide with bleeding,prolapse,and difficulty in defecation.Endoscopic rubber band ligation(ERBL)is a s... In the study,we comment on the article by Qu et al.Internal hemorrhoids are the most common anorectal disorders worldwide with bleeding,prolapse,and difficulty in defecation.Endoscopic rubber band ligation(ERBL)is a safe,convenient,quick,and economical outpatient procedure.The main goal of ERBL is to alleviate prolapse,but the high incidence of recurrence and post-procedural pain are of clinical concern.Polidocanol foam as a local hemostatic and anesthetic agent could reduce the rates of post-procedural pain and bleeding.Endoscopic polidocanol foam sclerobanding(EFSB)is a novel approach that could lift the mucosa for easy ligation and promote increased scarring in the submucosal tissue which translates into long-term relief from prolapse recurrence and reduced 24-h postprocedural pain.The study by Qu et al is a novel multi-center prospective randomized study to compare ERBL and EFSB in patients with grades II and III internal hemorrhoids with one-year follow-up.Results showed that EFSB is a novel therapy for internal hemorrhoids,but future studies with a larger sample,multiple treatment sessions,and long-term follow-up are required to confirm these findings. 展开更多
关键词 Internal hemorrhoids Goligher classification rubber band ligation SCLEROTHERAPY Polidocanol foam
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Massive gastrointestinal bleeding after endoscopic rubber band ligation of internal hemorrhoids:A case report 被引量:3
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作者 Yu-Dong Jiang Ying Liu +4 位作者 Jian-Di Wu Gang-Ping Li Jun Liu Xiao-Hua Hou Jun Song 《World Journal of Clinical Cases》 SCIE 2022年第19期6656-6663,共8页
BACKGROUND Rubber band ligation(RBL) using rigid anoscope is a commonly recommended therapy for grade Ⅰ-Ⅲ symptomatic internal hemorrhoids. Severe complications of RBL include pain, hemorrhage and sepsis. Flexible e... BACKGROUND Rubber band ligation(RBL) using rigid anoscope is a commonly recommended therapy for grade Ⅰ-Ⅲ symptomatic internal hemorrhoids. Severe complications of RBL include pain, hemorrhage and sepsis. Flexible endoscopic RBL(ERBL) is now more commonly used in RBL therapy but few severe complications have been reported. Here we report on a case of massive bleeding after ERBL.CASE SUMMARY A 31-year-old female was admitted to the department of gastroenterology with a chief complaint of discontinuous hematochezia for 2 years. No previous history, accompanying diseases or drug use was reported. Physical examination and colonoscopy showed grade Ⅱ internal hemorrhoids. The patient received ERBL therapy. Five days after ligation, the patient presented with mild hematochezia. On days 7 and 9 after ligation, she presented with a large amount of rectal bleeding, dizziness and weakness. Emergency colonoscopy revealed active bleeding and an ulcer in the anal wound. The patient received two sessions of hemoclipping on days 7 and 9 to treat the bleeding. No further bleeding was reported up to day 15 and she was discharged home. Although the hemorrhoid prolapse disappeared after ERBL, she was dissatisfied with the subsequent complications.CONCLUSION ERBL therapy is an effective treatment for symptomatic internal hemorrhoids with satisfactory short and long-term recovery. Pain and anal bleeding are the most frequently reported postoperative complications. Coagulation disorders complicate the increased risk of bleeding. Although rarely reported, our case reminds us that those patients without coagulation disorders are also at risk of massive life-threatening bleeding and need strict follow-up after ligation. 展开更多
关键词 Internal hemorrhoids ENDOSCOPY rubber band ligation COMPLICATION BLEEDING Case report
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Rubber band ligation of hemorrhoids: A guide for complications 被引量:26
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作者 Andreia Albuquerque 《World Journal of Gastrointestinal Surgery》 SCIE CAS 2016年第9期614-620,共7页
Rubber band ligation is one of the most important, costeffective and commonly used treatments for internal hemorrhoids. Different technical approaches were developed mainly to improve efficacy and safety. The techniqu... Rubber band ligation is one of the most important, costeffective and commonly used treatments for internal hemorrhoids. Different technical approaches were developed mainly to improve efficacy and safety. The technique can be employed using an endoscope with forward-view or retroflexion or without an endoscope, using a suction elastic band ligator or a forceps ligator. Single or multiple ligations can be performed in a single session. Local anaesthetic after ligation can also be used to reduce the post-procedure pain. Mild bleeding, pain, vasovagal symptoms, slippage of bands, priapism, difficulty in urination, anal fissure, and chronic longitudinal ulcers are normally considered minor complications, more frequently encountered. Massive bleeding, thrombosed hemorrhoids, severe pain, urinary retention needing catheterization, pelvic sepsis and death are uncommon major complications. Mild pain after rubber band ligation is the most common complication with a high frequency in some studies. Secondary bleeding normally occurs 10 to 14 d after banding and patients taking anti-platelet and/or anti-coagulant medication have a higher risk, with some reports of massive life-threatening haemorrhage. Several infectious complications have also been reported including pelvic sepsis, Fournier's gangrene, liver abscesses, tetanus and bacterial endocarditis. To date, seven deaths due to these infectious complications were described. Early recognition and immediate treatment of complications are fundamental for a favourable prognosis. 展开更多
关键词 hemorrhoids rubber band ligation PAIN BLEEDING INFECTION
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Redefining hemorrhoid therapy with endoscopic polidocanol foam sclerobanding
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作者 Asad Gul Rao Abdulqadir J Nashwan 《World Journal of Gastroenterology》 SCIE CAS 2024年第36期4021-4024,共4页
Hemorrhoids are a common and painful condition,with conventional treatments such as endoscopic rubber band ligation(ERBL)and injection sclerotherapy often falling short due to high recurrence rates and significant pos... Hemorrhoids are a common and painful condition,with conventional treatments such as endoscopic rubber band ligation(ERBL)and injection sclerotherapy often falling short due to high recurrence rates and significant post-operative pain.A clinical trial by Qu et al introduces a novel approach called endoscopic polidocanol foam sclerobanding(EFSB).This multicenter randomized trial involved 195 patients with grade II and III internal hemorrhoids and demonstrated that EFSB significantly reduced recurrence rates and post-procedural pain while improving symptom relief and patient satisfaction compared to ERBL.The study's strengths include its robust design,comprehensive outcome evaluation,and patient-centered approach.Despite limitations such as the single-blind design and relatively short follow-up period,the findings suggest that EFSB could enhance clinical practice by offering a more effective and patient-friendly treatment option.Further research is needed to validate these results and explore the long-term benefits and cost-effectiveness of EFSB. 展开更多
关键词 hemorrhoids endoscopic polidocanol foam sclerobanding rubber band ligation Injection sclerotherapy hemorrhoids recurrence Post-operative pain
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Rectal ulcers and massive bleeding after hemorrhoidal band ligation while on aspirin 被引量:3
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作者 Shruti Patel Ghulamullah Shahzad +3 位作者 Kaleem Rizvon Krishnaiyer Subramani Prakash Viswanathan Paul Mustacchia 《World Journal of Clinical Cases》 SCIE 2014年第4期86-89,共4页
Endoscopic hemorrhoidal band ligation is a well-established nonoperative method for treatment of bleeding internal hemorrhoids(grade 1 to 3). It is a safe and effective technique with a high success rate. Complication... Endoscopic hemorrhoidal band ligation is a well-established nonoperative method for treatment of bleeding internal hemorrhoids(grade 1 to 3). It is a safe and effective technique with a high success rate. Complications with this procedure are uncommon. Although rectal ulceration due to band ligation is a rare complication, it can cause life-threatening hemorrhage especially when patients are on medications which impair hemostasis like aspirin or non steroidal antiinflammatory drugs. We present 2 cases of massive lower gastro-intestinal bleeding in patients who had a band ligation procedure performed 2 wk prior to the presentation and were on aspirin at home. Both the patients were hemodynamically unstable requiring resuscitation. They required platelet and blood transfusions and were found to have rectal ulcers on colonoscopy done subsequently. The rectal ulcers corresponded to the site of band ligation. The use of aspirin by these patients would have caused defects in the hemostasis and may have predisposed them to massive bleeding in the presence of rectal ulcers occurring after the band ligation procedure. Managing aspirin before and after the ligation may be difficult especially since adequate guidelines are unavailable. Stopping aspirin in all the cases might not be safe and the decision should be individualized. 展开更多
关键词 hemorrhoids rubber band ligation RECTAL ULCERS Massive BLEEDING ASPIRIN
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Recent advances in the management of hemorrhoids 被引量:3
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作者 Mahmoud Sakr Khaled Saed 《World Journal of Surgical Procedures》 2014年第3期55-65,共11页
Hemorrhoids are considered one of the most common anorectal diseases with a prevalence of 4.4% up to 36.4% of the general population, and a peak incidence between 45 and 65 years. Hemorrhoidal disease presents with a ... Hemorrhoids are considered one of the most common anorectal diseases with a prevalence of 4.4% up to 36.4% of the general population, and a peak incidence between 45 and 65 years. Hemorrhoidal disease presents with a prolapsed lump, painless bleeding, discomfort, discharge, hygiene problems, soiling, and pruritus. Sliding anal canal lining theory is the most accepted theory as a cause of hemorrhoidal disease; however, it is also associated with hyper-vascularity, and, recently, with several enzymes or mediators involved in the disintegration of the tissues supporting the anal cushions, such as matrix metalloproteinase. A comprehensive search in published English-language literature till 2013 involving hemorrhoids was performed to construct this review article, which discusses advances in the management of hemorrhoids. This includes conservative treatment(life style modification, oral medications, and topical treatment), office procedures(rubber band ligation, injection sclerotherapy, infrared and radiofrequency coagulation, bipolar diathermy and direct-current electrotherapy, cryosurgery, and laser therapy), as well as surgical procedures including diathermy hemorrhoidectomy, Liga Sure hemorrhoidectomy, Harmonic scalpel hemorrhoidectomy, hemorrhoidal artery ligation, stapled hemorrhoidopexy(SH), and double SH. Results, merits and demerits of the different modalities of treatment of hemorrhoids are presented, in addition to the cost of the recent innovations. 展开更多
关键词 hemorrhoids rubber band Infrared PHOTOCOAGULATION CRYOSURGERY LIGASURE Harmonic Anopexy Hemorrhoidal ARTERY ligation Stapled hemorrhoidopexy
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内镜下串联套扎术与痔核套扎术治疗内痔的效果比较
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作者 吴诗虹 朱卫芳 +2 位作者 袁华兵 徐湖波 陈友平 《中国内镜杂志》 2024年第9期56-60,共5页
目的比较内镜下串联套扎术与痔核套扎术治疗内痔的疗效和并发症。方法回顾性分析2021年11月-2023年3月该院消化内科因便血住院治疗的120例Ⅰ~Ⅲ度内痔患者的临床资料。根据手术方式的不同,将接受内镜下痔核套扎术治疗的60例患者分为对照... 目的比较内镜下串联套扎术与痔核套扎术治疗内痔的疗效和并发症。方法回顾性分析2021年11月-2023年3月该院消化内科因便血住院治疗的120例Ⅰ~Ⅲ度内痔患者的临床资料。根据手术方式的不同,将接受内镜下痔核套扎术治疗的60例患者分为对照组;将接受内镜下串联套扎术治疗的60例患者分为治疗组。比较两组患者术后6个月内痔出血的治疗有效率、内痔脱垂疗效和术后并发症发生率。结果治疗组与对照组内痔出血的治疗有效率均为100.00%;治疗组治疗Ⅱ度内痔脱垂的疗效与对照组相当,差异无统计学意义(P>0.05),但治疗组治疗Ⅲ度内痔脱垂的疗效明显优于对照组,差异有统计学意义(P<0.01);治疗组术后肛门坠胀感的发生率高于对照组,差异有统计学意义(P<0.05);两组患者术后肛周疼痛、尿潴留和控便异常等并发症发生率比较,差异均无统计学意义(P>0.05),两组患者术后均未发生血栓性外痔等。结论内镜下串联套扎术与痔核套扎术治疗内痔出血的近期疗效相似,均能取得理想效果;两者治疗Ⅱ度内痔脱垂的近期疗效相似;内镜下串联套扎术治疗Ⅲ度内痔脱垂的近期疗效明显优于痔核套扎术;治疗组术后肛门坠胀感发生率高于对照组,其余并发症无明显差别。 展开更多
关键词 内痔 内镜下套扎治疗 串联套扎术 痔核套扎术 疗效
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耳穴压豆联合康复新液保留灌肠治疗内痔套扎术后溃疡的效果观察
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作者 徐玲燕 叶长根 +4 位作者 饶锦峰 姜慧腾 吴白慧 胡娜 杨力 《全科护理》 2024年第5期888-890,共3页
目的:探讨耳穴压豆联合康复新液保留灌肠治疗内镜下内痔套扎术后(ERBL)创面溃疡的效果及对病人术后疼痛、生活质量的影响。方法:选取2022年6月—2023年8月在医院接受ERBL治疗的80例内痔病人为研究对象,按随机数字表法将病人分为观察组... 目的:探讨耳穴压豆联合康复新液保留灌肠治疗内镜下内痔套扎术后(ERBL)创面溃疡的效果及对病人术后疼痛、生活质量的影响。方法:选取2022年6月—2023年8月在医院接受ERBL治疗的80例内痔病人为研究对象,按随机数字表法将病人分为观察组和对照组,每组40例。对照组给予康复新液保留灌肠治疗,观察组在ERBL术后给予康复新液保留灌肠+中医耳穴压豆法治疗。分别于病人术后第24小时、第3天、第7天、第12天应用视觉疼痛模拟评分量表(VAS)对病人的疼痛程度进行评价;病人出院时采用生活质量量表(GQOLI-74)、护理满意度调查表评价两组病人生活质量和护理满意度;比较两组病人创面愈合时间、疗效、并发症情况。结果:观察组病人术后第3天、第7天VAS评分低于对照组(P<0.05);观察组病人GQOLI-74评分及护理满意度评分高于对照组(P<0.05),创面愈合时间短于对照组;观察组病人临床有效率远高于对照组(P<0.05);两组病人住院期间并发症发生率比较差异无统计学意义(P>0.05)。结论:耳穴压豆联合康复新液保留灌肠能缓解病人ERBL术后疼痛,提高病人住院期间的生活质量和护理满意度,从而提高短期疗效,安全可靠。 展开更多
关键词 耳穴压豆 内镜下内痔套扎术 疼痛 临床疗效
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内镜下橡皮圈套扎术与经典外科手术吻合器痔上黏膜环切钉合术治疗痔疮的临床疗效 被引量:19
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作者 梁凤 乔晓 +3 位作者 韩成艳 陈倩倩 王昌成 刘树青 《中国内镜杂志》 2023年第2期13-19,共7页
目的对比研究内镜下橡皮圈套扎术(ERBL)与经典外科手术吻合器痔上黏膜环切钉合术(PPH)治疗痔疮的临床疗效。方法选取2018年1月-2020年1月在淮安市第二人民医院消化内科及胃肠外科住院,分别行ERBL及PPH的Ⅱ度和Ⅲ度痔疮患者各40例。观察... 目的对比研究内镜下橡皮圈套扎术(ERBL)与经典外科手术吻合器痔上黏膜环切钉合术(PPH)治疗痔疮的临床疗效。方法选取2018年1月-2020年1月在淮安市第二人民医院消化内科及胃肠外科住院,分别行ERBL及PPH的Ⅱ度和Ⅲ度痔疮患者各40例。观察组为ERBL手术患者,对照组为PPH手术患者,比较两组患者的手术时间、术中出血量、术后住院天数、术后早期和晚期并发症以及治疗效果。同时比较ERBL组套扎环数量与套扎早期和晚期并发症的相关性。结果ERBL组手术时间及术后住院时间明显短于PPH组,术中出血量明显少于PPH组,差异有统计学意义(均P=0.000);ERBL组术后早期并发症中疼痛及里急后重的发生率明显低于PPH组(P=0.004和P=0.044);两组患者治疗总有效率比较,差异无统计学意义(χ^(2)=0.26,P=0.608)。不同套扎环数量与ERBL术后早期及晚期并发症的发生无明显相关性(P>0.05)。结论ERBL及PPH治疗痔疮的总有效率相仿,但EBRL组手术时间及术后住院天数明显短于PPH组,术中出血量明显少于PPH组,且不同套扎环数量对ERBL术后早期及晚期并发症的发生无明显影响,ERBL用于治疗痔疮安全、有效,可应用于临床。 展开更多
关键词 内镜下橡皮圈套扎 吻合器痔上黏膜环切钉合手术 痔疮 临床疗效
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参照肛直线的内镜下胶圈套扎术治疗Ⅰ~Ⅲ度内痔伴出血患者的临床效果分析 被引量:2
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作者 丁辉 张昊 +7 位作者 李贞娟 徐闪闪 王艺 胡珊珊 白阳秋 杨惠 张慧敏 李修岭 《胃肠病学和肝病学杂志》 CAS 2023年第4期396-400,共5页
目的研究参照肛直线的内镜下胶圈套扎术(endoscopic rubber band ligation with reference to anal line,ERBL-RAL)对于内痔出血的改善情况。方法回顾性分析2020年1月至2022年4月在河南省人民医院消化内科诊断为内痔伴有出血和(或)脱垂... 目的研究参照肛直线的内镜下胶圈套扎术(endoscopic rubber band ligation with reference to anal line,ERBL-RAL)对于内痔出血的改善情况。方法回顾性分析2020年1月至2022年4月在河南省人民医院消化内科诊断为内痔伴有出血和(或)脱垂并行ERBL-RAL治疗的患者193例,根据纳入及排除标准共纳入139例进行研究,将其分为单纯出血组及出血并脱垂组,对其一般资料、临床特点、疗效及手术安全性进行分析。结果单纯出血组74例,出血合并脱垂组65例。套扎成功率100%,无脱环及术后大出血等不良事件发生。治疗后总体有效率97.8%,复发率5.8%,其中单纯出血组有效率98.6%,复发率4.1%;出血合并脱垂组有效率96.9%,复发率7.7%,复发的患者发生在术后3~6个月;术前出血评分为(2.86±0.09)分,术后评分为(1.35±0.06)分,治疗后患者出血较治疗前有明显改善(P<0.05);术后24 h内,22.3%(31/139)的患者出现疼痛,其中轻度19例(13.7%),中度10例(7.2%),重度2例(1.4%)。肛门坠胀51例(36.7%),排尿困难15例(10.8%),无发热患者出现,排便困难1例(0.7%)。术后内痔对患者生活质量影响较术前明显提高,差异有统计学意义(P<0.05)。结论ERBL-RAL可以明显改善患者出血症状及生活质量,且术后并发症发生率低,值得开展及推广。 展开更多
关键词 内镜 内痔 内镜下胶圈套扎术 内痔出血 肛直线
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内镜下痔上直肠黏膜套扎术治疗内痔的临床疗效
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作者 叶长根 朱晓佳 +5 位作者 冷芳 胡娜 戴华梅 向阳 方军 杨力 《当代医学》 2023年第29期96-98,共3页
目的探究内镜下痔上直肠黏膜套扎术(SHB)治疗内痔的临床疗效。方法回顾性分析2019年11月至2021年3月于景德镇市第三人民医院行内镜下套扎治疗的88例Ⅰ~Ⅲ级伴出血和/或脱垂症状内痔患者的临床资料,根据套扎位置不同分为内镜下痔核套扎术... 目的探究内镜下痔上直肠黏膜套扎术(SHB)治疗内痔的临床疗效。方法回顾性分析2019年11月至2021年3月于景德镇市第三人民医院行内镜下套扎治疗的88例Ⅰ~Ⅲ级伴出血和/或脱垂症状内痔患者的临床资料,根据套扎位置不同分为内镜下痔核套扎术(ERBL)组(n=47)和SHB组(n=41)。ERBL组行ERBL治疗,SHB组行SHB治疗,比较两组临床疗效、复发率及术后并发症发生率。结果两组治疗有效率和复发率比较差异无统计学意义。SHB组坠胀感、疼痛发生率均低于ERBL组,差异有统计学意义(P<0.05);两组出血、尿潴留发生率比较差异无统计学意义。结论内痔内镜下套扎术是一种可行、安全、有效的方法,SHB与ERBL疗效相当,但SHB术后并发症发生率更低,患者舒适度更高,更易接受。 展开更多
关键词 内痔 内镜下痔上直肠黏膜套扎术 内镜下痔核套扎术 复发率 并发症
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内镜下胶圈套扎联合复方角菜酸脂栓治疗内痔Ⅱ、Ⅲ期的疗效研究
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作者 张智 许丽玲 邓达宏 《外科研究与新技术》 2023年第1期50-52,共3页
目的 探究内镜下胶圈套扎联合复方角菜酸酯栓治疗内痔Ⅱ、Ⅲ期的疗效。方法 选取2022年4月—2022年11月期间东莞市石排医院60例愿意接受胶圈套扎治疗的内痔Ⅱ、Ⅲ期患者为研究对象,采用随机数字表法分为对照组和观察组,每组30例。对照... 目的 探究内镜下胶圈套扎联合复方角菜酸酯栓治疗内痔Ⅱ、Ⅲ期的疗效。方法 选取2022年4月—2022年11月期间东莞市石排医院60例愿意接受胶圈套扎治疗的内痔Ⅱ、Ⅲ期患者为研究对象,采用随机数字表法分为对照组和观察组,每组30例。对照组给予单纯胶圈套扎治疗,观察组给予胶圈套扎术后联合复方角菜酸酯栓治疗。比较两组术后不良反应发生率、治疗相关指标。结果 观察组不良反应发生率明显低于对照组(P<0.05)。观察组住院天数、治疗费用少于对照组(P<0.05)。观察组治疗后VAS评分低于治疗前,同时低于对照组(P<0.05)。结论 对内痔Ⅱ、Ⅲ期患者实施内镜下胶圈套扎联合复方角菜酸酯栓治疗可以缩短住院时间,减少治疗费用,缓解疼痛,减少不良反应,保障安全性。 展开更多
关键词 内痔 胶圈套扎 复方角菜酸酯栓 疗效
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CRH O′Regan套扎法治疗Ⅰ~Ⅲ度内痔的临床观察 被引量:6
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作者 胡宝春 马承华 +4 位作者 王雷 李晗 夏小 刘保全 胡铁头 《实用医学杂志》 CAS 北大核心 2013年第18期3034-3036,共3页
目的:探讨CRH O′Regan套扎法治疗内痔的临床疗效及安全性。方法:对414例Ⅰ~Ⅲ度内痔患者行痔上黏膜套扎治疗,治疗结束后第15天判断疗效并进行临床分析。结果:CRH O′Regan套扎法治疗内痔414例,完成治疗后15 d判断疗效,痊愈385例(9... 目的:探讨CRH O′Regan套扎法治疗内痔的临床疗效及安全性。方法:对414例Ⅰ~Ⅲ度内痔患者行痔上黏膜套扎治疗,治疗结束后第15天判断疗效并进行临床分析。结果:CRH O′Regan套扎法治疗内痔414例,完成治疗后15 d判断疗效,痊愈385例(93.0%),有效22例(5.3%),无效7例(1.7%),有效率98.3%。治疗后出现肛门坠胀感47例(11.3%),少量出血23例(5.6%),无术后疼痛、大量出血、感染等严重并发症。结论:CRH O′Regan套扎法能较好的治疗Ⅰ~Ⅲ度内痔,安全有效,微创无痛,操作方便。 展开更多
关键词 CRH O’Regan套扎法 内痔 微创 胶圈套扎
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改良ESD联合橡皮圈套扎切除治疗胃固有肌层小肿瘤的临床研究 被引量:7
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作者 邓全军 谢立群 +5 位作者 任万英 赵魁 李华 赵红艳 赵建业 张兴光 《天津医药》 CAS 2016年第12期1480-1483,共4页
目的探讨改良内镜黏膜下剥离术(ESD)联合橡皮圈套扎切除治疗胃固有肌层小肿瘤的疗效及安全性。方法选择经超声内镜(EUS)明确肿物(6 mm≤长径≤13 mm)来源于胃固有肌层的92例患者,在对患者实施静脉麻醉且气管插管状态下,先采用改良的ESD... 目的探讨改良内镜黏膜下剥离术(ESD)联合橡皮圈套扎切除治疗胃固有肌层小肿瘤的疗效及安全性。方法选择经超声内镜(EUS)明确肿物(6 mm≤长径≤13 mm)来源于胃固有肌层的92例患者,在对患者实施静脉麻醉且气管插管状态下,先采用改良的ESD剥离小肿物,暴露到一定程度后,采用橡皮圈套扎肿物,然后进行圈套器套扎切除。观察术中术后出血、穿孔情况,观察肿物切除的完整性、标本大小,对标本进行病理及免疫组化检查,术后对患者进行6及12个月的胃镜及EUS随访。结果 92例胃固有肌层小肿瘤均一次完整切除,手术平均操作时间(19.2±2.3)min,术中平均出血量(2.6±0.5)m L,切除后穿孔3例,均于内镜下金属止血夹联合尼龙绳结扎闭合创面。术后观察1周均无迟发性出血、穿孔等情况发生;标本大小6 mm×5 mm^13 mm×12 mm,术后病理诊断胃间质瘤73例(均为极低危险度),胃平滑肌瘤18例,胃神经纤维瘤1例;术后随访12个月,均未见残留、复发等情况。结论改良ESD联合橡皮圈套扎切除治疗胃固有肌层小肿瘤的疗效确切、安全,可完整切除病变,得到完整的病理学诊断资料,对评估肿瘤性质、恶性程度及患者预后有一定的意义。 展开更多
关键词 胃肿瘤 胃肠道间质肿瘤 胃镜检查 结扎术 内镜黏膜下剥离术 橡皮圈 胃固有肌层肿瘤
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透明帽辅助内镜下注射聚桂醇泡沫硬化剂治疗13例出血性内痔的临床观察 被引量:24
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作者 陈颖 陈炜 +5 位作者 方青青 张君佩 简佑容 祝子华 田怡 陈世耀 《上海医药》 CAS 2020年第9期17-22,共6页
目的:观察透明帽辅助内镜下注射聚桂醇泡沫硬化剂治疗出血性内痔的临床疗效和安全性。方法:对13例Ⅰ~Ⅲ度出血性内痔患者施行透明帽辅助内镜下注射聚桂醇泡沫硬化剂治疗,必要时联合胶圈套扎治疗,观察治疗效果、患者的术后并发症和满意... 目的:观察透明帽辅助内镜下注射聚桂醇泡沫硬化剂治疗出血性内痔的临床疗效和安全性。方法:对13例Ⅰ~Ⅲ度出血性内痔患者施行透明帽辅助内镜下注射聚桂醇泡沫硬化剂治疗,必要时联合胶圈套扎治疗,观察治疗效果、患者的术后并发症和满意度。结果:13例患者中,10例接受注射硬化剂治疗,3例接受注射硬化剂联合胶圈套扎治疗。术后12周随访,10例(76.9%)治愈,3例(23.1%)有效。在10例单纯注射硬化剂治疗的患者中,3例(30.0%)有轻至中度疼痛;在3例联合胶圈套扎治疗的患者中,2例(66.7%)疼痛需药物缓解。所有患者术后均无其他严重并发症。患者满意度高(100.0%)。结论:透明帽辅助经胃镜倒镜操作注射聚桂醇泡沫硬化剂治疗出血性内痔操作方便、安全性高,患者痛苦轻、恢复快,具有进一步研究和临床应用的价值。 展开更多
关键词 出血性内痔 透明帽辅助内镜下硬化术 胶圈套扎
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胶圈套扎术治疗内痔的疗效分析 被引量:4
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作者 鲁林源 朱贇 孙琼 《世界中西医结合杂志》 2011年第11期953-955,共3页
目的回顾性分析了胶圈套扎术(rubber band ligation,RBL)的短期疗效和长期疗效。方法 2001~2008年368名Ⅱ、Ⅲ期内痔患者在门诊接受了胶圈套扎术,每次套扎2~3个内痔。1个月和1年后回访所有患者;2~9年后,每例患者再行电话随访。结果 ... 目的回顾性分析了胶圈套扎术(rubber band ligation,RBL)的短期疗效和长期疗效。方法 2001~2008年368名Ⅱ、Ⅲ期内痔患者在门诊接受了胶圈套扎术,每次套扎2~3个内痔。1个月和1年后回访所有患者;2~9年后,每例患者再行电话随访。结果 1个月和1年后的短期随访显示,46%的患者术后24 h有轻、中度疼痛,4例(1%)患者由于疼痛严重在数天内再次到医院行痔切除术,只有2.4%的患者1周后出现直肠出血,20%患者1个月后行第2次RBL术;1年后随访,90%的Ⅱ期内痔患者及75%的Ⅲ期内痔患者无残留症状。2~9年的长期电话随访统计了302例(82%)患者,69%仍无症状,28%有残留症状,3%仍需进一步手术治疗。结论 RBL术治疗内痔是安全有效的,随访显示,其对Ⅱ、Ⅲ期内痔有良好的疗效。 展开更多
关键词 胶圈套扎术 痔切除术
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芍倍注射液辅助痔上黏膜错位套扎术治疗中重度痔疮临床观察 被引量:10
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作者 张春泽 付文政 贾岩峰 《中国中西医结合外科杂志》 CAS 2015年第3期261-264,共4页
目的:评价芍倍注射液辅助痔上黏膜环形错位套扎吻合术(EPH)治疗中重度痔疮的临床疗效。方法:将我院收治的72例中重度(Ⅲ~Ⅳ)痔患者随机分为两组,治疗组39例行芍倍注射液辅助EPH治疗,对照组33例行EPH治疗。观察比较两组患者手术时... 目的:评价芍倍注射液辅助痔上黏膜环形错位套扎吻合术(EPH)治疗中重度痔疮的临床疗效。方法:将我院收治的72例中重度(Ⅲ~Ⅳ)痔患者随机分为两组,治疗组39例行芍倍注射液辅助EPH治疗,对照组33例行EPH治疗。观察比较两组患者手术时间、术后并发症及治愈率的差异。结果:治疗组与对照组的手术时间分别为(15±5)min和(13±4)min,差异无统计学意义(t=1.74,P〉0.05);治愈率分别为治愈率为97.4%和96.7%,差异亦无统计学意义(t=0.71,P〉0.05)。治疗组和对照组出血量分别为(10±3)m L和(14±2)m L,差异有统计学意义(t=5.90,P〈0.05);治疗组无并发症发生,对照组有6例出现并发症,二者比较差异有统计学意义(P=0.013)。结论:芍倍注射液辅助EPH是治疗中重度痔疮的一种安全有效方法,具有操作简单,费用低,术后恢复快,并发症少及可重复操作等优点,值得临床推广。 展开更多
关键词 芍倍注射 痔疮 痔上黏膜环形错位套扎吻合术
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超声胃镜辅助内镜下诊治上消化道黏膜下肿物的探讨 被引量:2
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作者 刘宇慧 杨晓明 温章文 《大连医科大学学报》 CAS 2007年第2期153-155,共3页
[目的]探讨上消化道黏膜下肿物的内镜下诊断及治疗方法选择。[方法]对内镜下发现的黏膜下肿物进行超声胃镜或内镜下超声微探头检查,根据其回声强弱、肿物大小、浸润管壁的层次、边界情况,结合胃镜检查的镜下表现进行诊断并做出治疗方法... [目的]探讨上消化道黏膜下肿物的内镜下诊断及治疗方法选择。[方法]对内镜下发现的黏膜下肿物进行超声胃镜或内镜下超声微探头检查,根据其回声强弱、肿物大小、浸润管壁的层次、边界情况,结合胃镜检查的镜下表现进行诊断并做出治疗方法的选择。[结果]超声检查的黏膜下肿物共78例,其中黏膜下平滑肌瘤和<2 cm的良性间质瘤共56例,行内镜下橡皮圈结扎术49例,成功率为100%,未发生出血、穿孔等并发症;黏膜下囊肿和黏膜下脂肪瘤6例,行内镜下高频电切术,无并发症发生;较大的间质瘤和恶性间质瘤13例,建议手术治疗,术后病理组织检查11例与胃镜检查符合,1例为胃手术后肉芽组织增生表现,另外1例为克隆氏病;异位胰腺3例。[结论]超声内镜可以协助诊断消化道黏膜下肿物的性质;内镜下橡皮圈结扎法是治疗直径<2 cm的黏膜下肿物安全有效的手段。 展开更多
关键词 超声内镜 黏膜下肿物 结扎术
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