Objective: To retrospectively evaluate the feasibility and clinical value of video assisted endoscopic thyroidectomy by the breast approach. Methods: From December 2002 to May 2003, 28 patients with a mean age of 28 ...Objective: To retrospectively evaluate the feasibility and clinical value of video assisted endoscopic thyroidectomy by the breast approach. Methods: From December 2002 to May 2003, 28 patients with a mean age of 28 years (range from 20 to 45 years) were selected and given video assisted endoscopic thyroidectomy by the breast approach. The subcutaneous space in the breast area and the subplatysmal space in the neck were bluntly dissociated through a 10 mm incision between the nipples, and CO 2 was insufflated at 6 8 kban to create the operative space. Three trocars were inserted in the mammary regions, and dissection of the thyroid and division of the thyroid vessels and parenchyma were performed endoscopically using an ultrasonically activated scalpel. The recurrent laryngeal nerve, the superior laryngeal nerve, and the parathyroid glands were preserved properly. Results: Among the patients, 3 were mass resections, 17 subtotal lobectomies, 2 total lobectomies, and 6 subtotal lobectomies plus contralateral mass resections. The mean operative time was (87.1±26.0) min; the mean estimated blood loss was (47.9±19.6) ml; and the mean postoperative hospital stay was (3.4±0.7) d. The drainage tubes were pulled out at 36 60 h postoperatively. There were no conversions to open surgery or complications. No scars left in the neck, and the patients were satisfied with the postoperative appearance. Conclusion: Video assisted endoscopic thyroidectomy using a breast approach and low pressure subcutaneous CO 2 insufflation is a feasible and safe procedure, which results in satisfactory appearance. We believe that video assisted endoscopic thyroidectomy by such approach will play a role in the future.展开更多
Objective:To study the effect of the application of inflation fluid containing ropivacaine hydrochloride in endoscopic thyroidectomy on stress response and pain mediators. Methods:128 patients receiving endoscopic thy...Objective:To study the effect of the application of inflation fluid containing ropivacaine hydrochloride in endoscopic thyroidectomy on stress response and pain mediators. Methods:128 patients receiving endoscopic thyroidectomy in our hospital between November 2015 and November 2016 were selected and randomly divided into two groups (n=64), observation group of patients received the inflation fluid containing ropivacaine hydrochloride as the inflating medium during endoscopic thyroidectomy and control group of patients received saline inflation fluid as the inflating medium during endoscopic thyroidectomy. Serum was collected before and after operation respectively to determine the levels of stress response-related hormones and pain-related mediators. Results:Serum adrenocorticotropic hormone (ACTH), cortisol (Cor), norepinephrine (NE), epinephrine (E), renin (PRA), angiotensin-2 (ANG-2), aldosterone (ALD), dynorphin (DYN),β-endorphin (β-EP), nitric oxide (NO) and substance P (SP) levels of both groups after operation were significantly higher than those before operation (P<0.05), and serum ACTH, Cor, NE, E, PRA, ANG-2, ALD, DYN,β-EP, NO and SP levels of observation group after operation were significantly lower than those of control group (P<0.05). Conclusions:The application of inflation fluid containing ropivacaine hydrochloride in endoscopic thyroidectomy can reduce the postoperative stress response and suppress pain mediator secretion.展开更多
Introduction: The aim of the study was to compare the feasibility and safety of endoscopic thyroid lobectomy via axillary-breast-shoulder approach (ET via ABS) with a conventional open thyroid lobectomy (OT). Methods:...Introduction: The aim of the study was to compare the feasibility and safety of endoscopic thyroid lobectomy via axillary-breast-shoulder approach (ET via ABS) with a conventional open thyroid lobectomy (OT). Methods: From November 2014 to December 2015, 20 patients with unilateral benign thyroid nodules were treated with ET via ABS and another 20 patients were treated with an OT. We analyzed the clinical characteristics postoperative complications, pain, and patient satisfaction. Results: No statistically significant differences occurred between groups except the mean ages of the OT group and the ET via ABS group were 55 and 44 years, respectively (p = 0.015). The mean operative time was almost the same in both groups (116 min in the OT group and 114 min in the ET via ABS group). Blood loss was significantly higher in the OT group than in the ET via ABS group (p = 0.042) but postoperative drainage was detected more in the ET via ABS group (p p = 0.026). The hospital stay was three days in OT group and four days in ET via ABS group (p = 0.909). Postoperative complications such as hematoma, hoarseness, dysphagia, and prolonged subcutaneous emphysema were detected only in the ET via ABS group but without statistical difference. More patients were “very satisfied” with the treatment in the ET via ABS group than in the OT group. Conclusion: The ET via ABS is as safe and effective as the OT for patients with unilateral thyroid nodules. With less early postoperative pain and higher patient satisfaction, this endoscopic thyroidectomy approach should be considered in patients who concern about cosmetic results.展开更多
目的探讨超声引导下胸壁神经阻滞在经腋窝入路腔镜甲状腺手术患者围术期镇痛效果及术后恢复的影响,并评估其有效性和安全性。方法选取60例接受经腋窝腔镜甲状腺手术患者,按照随机数字表法分为两组:超声引导下胸壁神经阻滞复合全身麻醉...目的探讨超声引导下胸壁神经阻滞在经腋窝入路腔镜甲状腺手术患者围术期镇痛效果及术后恢复的影响,并评估其有效性和安全性。方法选取60例接受经腋窝腔镜甲状腺手术患者,按照随机数字表法分为两组:超声引导下胸壁神经阻滞复合全身麻醉组(P组)和单纯全身麻醉组(C组),每组30例。P组在超声引导下行PecsⅠ联合PecsⅡ阻滞后,两组患者均接受气管插管下的全身麻醉,比较两组患者的围手术期镇痛效果和术后恢复情况。结果在围术期镇痛效果方面,P组患者在术中舒芬太尼使用量、术后补救镇痛次数及补救镇痛时酮咯酸氨丁三醇使用量均明显低于C组(P<0.05),在术后3、6、12 h,P组患者静息及运动状态下的NRS评分也显著低于C组(P<0.05);在术后恢复质量方面,P组患者苏醒时间、PACU停留时间明显短于C组(P<0.05),术后24 h QoR-40量表评分总分及身体舒适度、疼痛维度评分均高于C组(P<0.05)。结论超声引导下胸壁神经阻滞在经腋窝腔镜甲状腺手术中展现出良好的镇痛效果,且有助于患者的术后恢复。展开更多
文摘Objective: To retrospectively evaluate the feasibility and clinical value of video assisted endoscopic thyroidectomy by the breast approach. Methods: From December 2002 to May 2003, 28 patients with a mean age of 28 years (range from 20 to 45 years) were selected and given video assisted endoscopic thyroidectomy by the breast approach. The subcutaneous space in the breast area and the subplatysmal space in the neck were bluntly dissociated through a 10 mm incision between the nipples, and CO 2 was insufflated at 6 8 kban to create the operative space. Three trocars were inserted in the mammary regions, and dissection of the thyroid and division of the thyroid vessels and parenchyma were performed endoscopically using an ultrasonically activated scalpel. The recurrent laryngeal nerve, the superior laryngeal nerve, and the parathyroid glands were preserved properly. Results: Among the patients, 3 were mass resections, 17 subtotal lobectomies, 2 total lobectomies, and 6 subtotal lobectomies plus contralateral mass resections. The mean operative time was (87.1±26.0) min; the mean estimated blood loss was (47.9±19.6) ml; and the mean postoperative hospital stay was (3.4±0.7) d. The drainage tubes were pulled out at 36 60 h postoperatively. There were no conversions to open surgery or complications. No scars left in the neck, and the patients were satisfied with the postoperative appearance. Conclusion: Video assisted endoscopic thyroidectomy using a breast approach and low pressure subcutaneous CO 2 insufflation is a feasible and safe procedure, which results in satisfactory appearance. We believe that video assisted endoscopic thyroidectomy by such approach will play a role in the future.
文摘Objective:To study the effect of the application of inflation fluid containing ropivacaine hydrochloride in endoscopic thyroidectomy on stress response and pain mediators. Methods:128 patients receiving endoscopic thyroidectomy in our hospital between November 2015 and November 2016 were selected and randomly divided into two groups (n=64), observation group of patients received the inflation fluid containing ropivacaine hydrochloride as the inflating medium during endoscopic thyroidectomy and control group of patients received saline inflation fluid as the inflating medium during endoscopic thyroidectomy. Serum was collected before and after operation respectively to determine the levels of stress response-related hormones and pain-related mediators. Results:Serum adrenocorticotropic hormone (ACTH), cortisol (Cor), norepinephrine (NE), epinephrine (E), renin (PRA), angiotensin-2 (ANG-2), aldosterone (ALD), dynorphin (DYN),β-endorphin (β-EP), nitric oxide (NO) and substance P (SP) levels of both groups after operation were significantly higher than those before operation (P<0.05), and serum ACTH, Cor, NE, E, PRA, ANG-2, ALD, DYN,β-EP, NO and SP levels of observation group after operation were significantly lower than those of control group (P<0.05). Conclusions:The application of inflation fluid containing ropivacaine hydrochloride in endoscopic thyroidectomy can reduce the postoperative stress response and suppress pain mediator secretion.
文摘Introduction: The aim of the study was to compare the feasibility and safety of endoscopic thyroid lobectomy via axillary-breast-shoulder approach (ET via ABS) with a conventional open thyroid lobectomy (OT). Methods: From November 2014 to December 2015, 20 patients with unilateral benign thyroid nodules were treated with ET via ABS and another 20 patients were treated with an OT. We analyzed the clinical characteristics postoperative complications, pain, and patient satisfaction. Results: No statistically significant differences occurred between groups except the mean ages of the OT group and the ET via ABS group were 55 and 44 years, respectively (p = 0.015). The mean operative time was almost the same in both groups (116 min in the OT group and 114 min in the ET via ABS group). Blood loss was significantly higher in the OT group than in the ET via ABS group (p = 0.042) but postoperative drainage was detected more in the ET via ABS group (p p = 0.026). The hospital stay was three days in OT group and four days in ET via ABS group (p = 0.909). Postoperative complications such as hematoma, hoarseness, dysphagia, and prolonged subcutaneous emphysema were detected only in the ET via ABS group but without statistical difference. More patients were “very satisfied” with the treatment in the ET via ABS group than in the OT group. Conclusion: The ET via ABS is as safe and effective as the OT for patients with unilateral thyroid nodules. With less early postoperative pain and higher patient satisfaction, this endoscopic thyroidectomy approach should be considered in patients who concern about cosmetic results.
文摘目的探讨超声引导下胸壁神经阻滞在经腋窝入路腔镜甲状腺手术患者围术期镇痛效果及术后恢复的影响,并评估其有效性和安全性。方法选取60例接受经腋窝腔镜甲状腺手术患者,按照随机数字表法分为两组:超声引导下胸壁神经阻滞复合全身麻醉组(P组)和单纯全身麻醉组(C组),每组30例。P组在超声引导下行PecsⅠ联合PecsⅡ阻滞后,两组患者均接受气管插管下的全身麻醉,比较两组患者的围手术期镇痛效果和术后恢复情况。结果在围术期镇痛效果方面,P组患者在术中舒芬太尼使用量、术后补救镇痛次数及补救镇痛时酮咯酸氨丁三醇使用量均明显低于C组(P<0.05),在术后3、6、12 h,P组患者静息及运动状态下的NRS评分也显著低于C组(P<0.05);在术后恢复质量方面,P组患者苏醒时间、PACU停留时间明显短于C组(P<0.05),术后24 h QoR-40量表评分总分及身体舒适度、疼痛维度评分均高于C组(P<0.05)。结论超声引导下胸壁神经阻滞在经腋窝腔镜甲状腺手术中展现出良好的镇痛效果,且有助于患者的术后恢复。
