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Mapping Quantitative Trait Loci Controlling Endosperm Traits with Molecular Marker 被引量:1
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作者 XU Chen-wu, LI Tao, SUN Chang-sen and GU Shi-Hang( Laboratory of Quantitative Genetics , Yangzhou University, Yangzhou 225009) 《Agricultural Sciences in China》 CAS CSCD 2002年第1期5-10,共6页
Based on the genetic models for triploid endosperm traits and on the methods for mapping diploid quantitative traits loci (QTLs), the genetic constitutions, components of means and genetic variances of QTL controlling... Based on the genetic models for triploid endosperm traits and on the methods for mapping diploid quantitative traits loci (QTLs), the genetic constitutions, components of means and genetic variances of QTL controlling endosperm traits under flanking marker genotypes of different generations were presented. From these results, a multiple linear regression method for mapping QTL underlying endosperm traits in cereals was proposed, which used the means of endosperm traits under flanking marker genotypes as a dependent variable, the coefficient of additive effect (d) and dominance effect (h1 and/or h2) of a putative QTL in a given interval as independent variables. This method can work at any position in a genome covered by markers and increase the estimation precision of QTL location and their effects by eliminating the interference of other relative QTLs. This method can also be easily used in other uneven data such as markers and quantitative traits detected or measured in plants and tissues different either in generations or at chromosomal ploidy levels, and in endosperm traits controlled by complicated genetic models considering the effects produced by genotypes of both maternal plants and seeds on them. 展开更多
关键词 endosperm traits quantitative trait loci multiple linear regression molecular marker
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构建数量性状基因图的双侧标记基因型均值回归法 被引量:5
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作者 徐辰武 顾世梁 《扬州大学学报(自然科学版)》 CAS CSCD 1999年第1期42-47,共6页
提出一种构建数量性状基因(QTL)图的双侧标记基因型均值回归法.该方法利用染色体上某一区间的双侧标记基因型的数量性状均值为依变数,以该区间内任一点假定存在QTL的加性效应和显性效应的系数为自变数进行二元线性回归分析,... 提出一种构建数量性状基因(QTL)图的双侧标记基因型均值回归法.该方法利用染色体上某一区间的双侧标记基因型的数量性状均值为依变数,以该区间内任一点假定存在QTL的加性效应和显性效应的系数为自变数进行二元线性回归分析,估计出QTL的加性和显性效应,并测验该点是否存在QTL,QTL的最可能位置则根据测验统计数取最大值的点而确定;同时,在某一标记区间测验时,利用多元线性回归方法将该区间外可能存在的QTL进行统计控制.该方法简便易行。 展开更多
关键词 基因定位 分子标记 均值回归法 数量性状基因图
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胚乳性状数量基因的定位方法(英文) 被引量:1
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作者 徐辰武 李韬 +1 位作者 孙长森 顾世梁 《生命科学研究》 CAS CSCD 2001年第4期314-320,共7页
将三倍体胚乳性状的数量遗传模型和二倍体性状数量基因 (QTL)图构建方法相结合 ,导出双侧标记基因型下有关胚乳性状 QTL的遗传组成、平均数和遗传方差分量 ,据之提出以某一区间双侧标记基因型胚乳性状的平均值为依变数 ,以该区间内任一... 将三倍体胚乳性状的数量遗传模型和二倍体性状数量基因 (QTL)图构建方法相结合 ,导出双侧标记基因型下有关胚乳性状 QTL的遗传组成、平均数和遗传方差分量 ,据之提出以某一区间双侧标记基因型胚乳性状的平均值为依变数 ,以该区间内任一点假定存在的 QTL 的加性效应 d、显性效应 h1 和 /或 h2 的系数为自变数 ,进行有重复观察值的多元线性回归分析 ,根据多元线性回归的显著性测验该点是否存在 QTL ,并估计出 QTL 的遗传效应 .给定区间内任一点 ,皆可以此进行分析 ,从而可在整条染色体上作图 ,并以之确定QTL的数目和最可能位置 .同时 ,在检测某一区间时 ,利用多元线性回归方法将该区间外可能存在的 QTL的干扰进行统计控制 ,以提高 QTL 检测的精度 .此外 ,还讨论了如何将之推广应用于其他类型的 展开更多
关键词 胚乳性状 数量基因 多元线性回归 分子标记 基因定位
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A correlation method of detecting and estimating interactions of QTLs
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作者 HU Zhongli SUN Qixin +2 位作者 ZHANG Xiufu SONG Yunchun ZHANG Qifa 《Chinese Science Bulletin》 SCIE EI CAS 2002年第8期664-667,共4页
More and more studies demonstrate that a great deal of interactions among the quantitative trait loci (QTLs) are far more than those detected by single markers. A correlation method was proposed for estimating the int... More and more studies demonstrate that a great deal of interactions among the quantitative trait loci (QTLs) are far more than those detected by single markers. A correlation method was proposed for estimating the interactions of multiple QTLs detected by multi-markers in several mapping populations. Genetic implication of this method and usage were discussed. 展开更多
关键词 quantitative trait loci EPISTASIS molecular marker cor-relation method multiple regression.
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