Objective This study aimed to measure the basal energy expenditure(BEE)of Chinese healthy adults and establish an accurate predictive equation for this population.Methods In total,470 Chinese healthy adults had their ...Objective This study aimed to measure the basal energy expenditure(BEE)of Chinese healthy adults and establish an accurate predictive equation for this population.Methods In total,470 Chinese healthy adults had their BEE measured using the Cosmed K4b2 portable metabolic system.Multiple linear regression analysis was applied to develop new optimal equations for predicting BEE.The bias,accuracy rate,concordance correlation coefficient(CCC),and root mean square error(RMSE)were used to evaluate the accuracy of the predictive equations.Results There was a significant difference in BEE between males and females,with 5,954 kJ/d and 5,089 kJ/d,respectively.People living in rural areas expended significantly higher BEE(5,885 kJ/d)than those in urban areas(5,279 kJ/d).Previous equations developed by Henry,Schofield,Harris-Benedict(HB),and Liu overestimated the BEE of Chinese healthy adults.The new equations derived from the present study displayed the smallest average bias and RMSE from the measured basal energy expenditure(mBEE).The CCC of the new equations was higher than other predictive equations,but it was lower than 0.8.There was no significant difference in the accuracy rate among all predictive equations.Conclusions Sex and regional differences in BEE were observed in Chinese healthy adults.Neither the widely used previous predictive equations nor the one derived in the present study were accurate enough for estimating the BEE of Chinese healthy adults.Further study is required to develop more accurate equations for predicting the BEE of Chinese healthy adults aged between 20–45 years.展开更多
AIM: To evaluate selected factors influencing resting energy expenditure(REE) in obese female subjects.METHODS: Seventy seven 61 obese Caucasian women [mean age of 52.93 ± 13.45 years, and mean body mass index(BM...AIM: To evaluate selected factors influencing resting energy expenditure(REE) in obese female subjects.METHODS: Seventy seven 61 obese Caucasian women [mean age of 52.93 ± 13.45 years, and mean body mass index(BMI) of 41.78 ± 11.54 kg/m2] were enrolled; measurements of resting metabolic rate(RMR) by a ventilated, open-circuit system, indirect calorimeter were performed after an overnight fast. Body composition as well as medications, physical parameters, blood samples, disease pattern, and smoking were considered. RESULTS: RMR was significantly associated with body weight(r = 0.732, P < 0.001), body height(r = 0.401,P = 0.008), BMI(r = 0.504, P < 0.001), waist circumference(r = 0.602, P < 0.001), mid-upper arm circumference(r = 0.417, P = 0.006), mid-upper arm muscle circumference(r = 0.344, P = 0.028), total body water(r = 0.339, P = 0.035), body temperature(r = 0.409, P = 0.007), smoking(P = 0.031), serum T4 levels(r = 0.331, P = 0.036), obstructive sleep apnoea syndrome(OSAS; P = 0.023), impaired glucose tolerance(IGT; P = 0.017) and impaired glycaemic status, including hyperinsulinism, IGT and diabetes mellitus(P = 0.003).CONCLUSION: Future research should be prompted to optimize the procedure of indirect calorimetry to achieve clinical benefits in obese subjects.展开更多
BACKGROUND Malnutrition affects 20%to 50%of patients with cirrhosis.It may be associated with serious complications and has a direct impact on prognosis.Resting energy expenditure(REE)is an important parameter to guid...BACKGROUND Malnutrition affects 20%to 50%of patients with cirrhosis.It may be associated with serious complications and has a direct impact on prognosis.Resting energy expenditure(REE)is an important parameter to guide the optimization of therapy and recovery of nutritional status in patients with cirrhosis.However,the REE of patients with cirrhosis is still unclear,casting doubt upon the optimal nutritional management approach.AIM To identify the best method that predicts the REE of cirrhotic patients,using indirect calorimetry(IC)as the gold standard.METHODS An observational study was performed on 90 patients with cirrhosis.REE was assessed by IC,bioelectrical impedance analysis(BIA),and predictive formulas,which were compared using Bland-Altman plots and the Student’s t-test.RESULTS REE values measured by IC(1607.72±257.4 kcal)differed significantly from those determined by all other methods(BIA:1790.48±352.1 kcal;Harris&Benedict equation:2373.54±254.9 kcal;IOM equation:1648.95±185.6 kcal;Cunningham equation:1764.29±246.2 kcal),except the Food and Agriculture Organization of the United Nations,World Health Organization,and United Nations University(FAO/WHO/UNU)(1616.07±214.6 kcal)and McArdle(1611.30±241.8 kcal)equations.We found no significant association when comparing IC and 24-h dietary recall among different Child-Pugh classes of cirrhosis.CONCLUSION The IOM and FAO/WHO/UNU equations have the best agreement with the CI.These results indicate a possibility of different tools for the clinical practice on cirrhotic patients.展开更多
目的:通过比较肥胖青少年基础代谢率实测值与公式推测值的一致性,探讨以性别、年龄、身高和体重为主要参数的基础代谢率推测公式能否适用于中国肥胖青少年。方法:以66名中国肥胖青少年(男32人,女34人)为对象,晨起空腹进行相关人体测量,...目的:通过比较肥胖青少年基础代谢率实测值与公式推测值的一致性,探讨以性别、年龄、身高和体重为主要参数的基础代谢率推测公式能否适用于中国肥胖青少年。方法:以66名中国肥胖青少年(男32人,女34人)为对象,晨起空腹进行相关人体测量,并采用便携式气体代谢分析仪测定受试者的基础代谢率,区分性别后分别比较采用Harris and Benedict公式、Schofield公式和Mifflin公式计算的基础代谢率与实测值的差异。结果:中国肥胖青少年基础代谢率采用Mifflin公式和Harris and Benedict公式的推测值与实测值相比,偏倚较小,Mifflin公式为-5.79 kcal/d(男)和-57.45 kcal/d(女),Harris and Benedict公式为-109.86 kcal/d(男)和-63.76 kcal/d(女),均在临床可接受的范围(-250 kcal/d,250 kcal/d)内。Harris and Benedict公式推测男女肥胖青少年基础代谢率的一致性界限分别为(男:-732.16 kcal/d,512.45 kcal/d)和(女:-595.01 kcal/d,467.49 kcal/d),Mifflin公式推测男女肥胖青少年基础代谢率的一致性界限分别为(男:-597.91 kcal/d,586.33 kcal/d)和(女:-603.01,531.84),均超出临床可接受范围。Schofield公式计算女性肥胖青少年基础代谢率的推测值与实测值相比,偏倚为-123.69 kcal/d,计算男性肥胖青少年基础代谢率的推测值与实测值的偏倚为-260.35 kcal/d,其一致性界限超出临床可接受范围。结论:Harris and Benedict公式、Schofield公式和Mifflin公式用于评估中国肥胖青少年基础代谢率时,其推测值与实测值的一致性界限均超出临床可接受范围,以上三个公式所得基础代谢率推测值与间接测热法实测值一致性较差,评估中国肥胖青少年基础代谢率的准确性不够。展开更多
目的观察老年胃肠道肿瘤病人静息能量代谢(Resting Energy Expenditure,REE)的特点。方法选择老年(≥60岁)胃肠道肿瘤患者和非肿瘤患者(对照组)各60例,应用间接测热仪对其进行REE测定,根据MNA法评价营养状况,计算Harris-Benedict公式预...目的观察老年胃肠道肿瘤病人静息能量代谢(Resting Energy Expenditure,REE)的特点。方法选择老年(≥60岁)胃肠道肿瘤患者和非肿瘤患者(对照组)各60例,应用间接测热仪对其进行REE测定,根据MNA法评价营养状况,计算Harris-Benedict公式预测值。结果老年男性肿瘤患者REE较对照组低,且差异有统计学意义;H-B公式预测值明显高于REE测定值,差异有统计学意义;临床估计能量供给的经验值平均为REE测量值的1.5倍。结论老年胃肠道肿瘤患者静息能量消耗较非肿瘤患者有所下降,H-B公式法不能准确预测病人的能量消耗,经验估计值可能会造成过度喂养。展开更多
间接测热法(indirect calorimetry,IC)是能量测定的金标准。通过分析呼吸中的气体来计算总能量消耗(total energy expenditure,TEE),其准确率高。本综述介绍了间接测热法的原理、临床应用及局限性,也强调了间接测热设备的使用要点,解释...间接测热法(indirect calorimetry,IC)是能量测定的金标准。通过分析呼吸中的气体来计算总能量消耗(total energy expenditure,TEE),其准确率高。本综述介绍了间接测热法的原理、临床应用及局限性,也强调了间接测热设备的使用要点,解释了测量结果的具体意义,以期临床上能更好使用间接测热设备。展开更多
背景:SWA(Sense Wear Pro Armband)是一种由多种运动传感器所结合的体力活动能量消耗监控设备。其在近年来被广泛应用于体力活动能量消耗的研究中。目的:对SWA准确性、软件版本、佩戴时间、不同人群和不同体力活动水平等不同方面的应用...背景:SWA(Sense Wear Pro Armband)是一种由多种运动传感器所结合的体力活动能量消耗监控设备。其在近年来被广泛应用于体力活动能量消耗的研究中。目的:对SWA准确性、软件版本、佩戴时间、不同人群和不同体力活动水平等不同方面的应用情况进行汇总,期望能为今后SWA的使用提供一些实用性的参考。方法:检索2015年1月前公开发表于CNKI全文数据库及PubM ed文摘数据库的论文。文献筛选标准为:1在CNKI全文数据库中以"体力活动,Armband,能量消耗"为关键词进行搜索。2检索Pubmed文摘数据库、Web of Science数据库,关键词为"Physical activity,Sense Wear Pro Armband,Energy Expenditure,Review"。以发表在核心期刊者或SCI数据库收录者优先。结果与结论:双标水、间接测热法等方法为标准的校标研究显示,SWA具有较高的准确性,能有效评估日常体力活动的能量消耗。但在特殊情况下也存在一定的差异,例如不同的人群、运动强度等。与此同时,确定恰当的佩戴时间和数据统计时使用软件版本也是影响最终结果准确性的因素之一。SWA能准确预测体力活动能耗,但针对不同人群、运动强度等情况应有必要对SWA的计算公式进一步的进行改进。展开更多
目的以间接测热法测定的静息能量消耗(resting energy expenditure,REE)为金标准,结合体成分指标建立能量消耗预测公式,为寻找客观、准确、重复性高及可操作性强的飞行人员REE测量方法提供参考。方法纳入正常体型男性志愿者14名,通过低...目的以间接测热法测定的静息能量消耗(resting energy expenditure,REE)为金标准,结合体成分指标建立能量消耗预测公式,为寻找客观、准确、重复性高及可操作性强的飞行人员REE测量方法提供参考。方法纳入正常体型男性志愿者14名,通过低压舱构建低压低氧战训环境。所有受试者均按要求完成单任务(飞行操作)和双任务(飞行操作+计算任务)。使用体成分分析仪直接测定受试者体重、去脂体重(fat free mass,FFM)、肌肉重(muscle mass,MM)、脂肪重(fat mass,FM)、腰臀比(waist-to-hip ratio,WHR)、内脏脂肪重(visceral fat mass,VFM)及体脂率(body fat percentage,BF%),使用气体代谢仪监测其呼吸频率(respiratory frequency,RF)、CO_(2)产生量(volume of CO_(2),VCO_(2))、最大摄氧量(maximal volume of O_(2),VO_(2max))、潮气量(volume of tidal,VT)、每分通气量(minute ventilation volume,VE)、代谢当量(metablic equivalent,MET)、REE和每公斤体重每日静息能量消耗(REE/kg/d)。统计分析REE与体成分检测指标的相关性,并获得线性回归方程。结果在模拟低压低氧环境下,双任务时受试者的RF、VCO_(2)、VO_(2max)、VE、VT、REE、REE/kg/d、MET和心率略有增加趋势,但和单任务相比,其差异均无统计学意义(P均>0.05);REE与FFM、MM呈正相关(r=0.566、0.570,P=0.035、0.033),而与身高、FM和心率等无相关性(P均>0.05)。线性回归方程显示低压低氧环境下REE预测公式为模型A:REE=60.34×MM-1121(r=0.570,P=0.033),或模型B:REE=55.34×FFM-1073(r=0.566,P=0.035);模型A公式预测值与实测值REE具有正相关性(r=0.570,P=0.033),且误差值为(0.032±358.170)kcal/d,P=1.00>0.05。结论低压低氧环境下正常体型受试者的REE主要决定因素为FFM和MM,通过测定FFM或MM均可方便、准确地预测其REE水平。展开更多
基金Supported by Key Projects of the National Science and Technology Pillar Program[No.2008BAI58B01].
文摘Objective This study aimed to measure the basal energy expenditure(BEE)of Chinese healthy adults and establish an accurate predictive equation for this population.Methods In total,470 Chinese healthy adults had their BEE measured using the Cosmed K4b2 portable metabolic system.Multiple linear regression analysis was applied to develop new optimal equations for predicting BEE.The bias,accuracy rate,concordance correlation coefficient(CCC),and root mean square error(RMSE)were used to evaluate the accuracy of the predictive equations.Results There was a significant difference in BEE between males and females,with 5,954 kJ/d and 5,089 kJ/d,respectively.People living in rural areas expended significantly higher BEE(5,885 kJ/d)than those in urban areas(5,279 kJ/d).Previous equations developed by Henry,Schofield,Harris-Benedict(HB),and Liu overestimated the BEE of Chinese healthy adults.The new equations derived from the present study displayed the smallest average bias and RMSE from the measured basal energy expenditure(mBEE).The CCC of the new equations was higher than other predictive equations,but it was lower than 0.8.There was no significant difference in the accuracy rate among all predictive equations.Conclusions Sex and regional differences in BEE were observed in Chinese healthy adults.Neither the widely used previous predictive equations nor the one derived in the present study were accurate enough for estimating the BEE of Chinese healthy adults.Further study is required to develop more accurate equations for predicting the BEE of Chinese healthy adults aged between 20–45 years.
文摘AIM: To evaluate selected factors influencing resting energy expenditure(REE) in obese female subjects.METHODS: Seventy seven 61 obese Caucasian women [mean age of 52.93 ± 13.45 years, and mean body mass index(BMI) of 41.78 ± 11.54 kg/m2] were enrolled; measurements of resting metabolic rate(RMR) by a ventilated, open-circuit system, indirect calorimeter were performed after an overnight fast. Body composition as well as medications, physical parameters, blood samples, disease pattern, and smoking were considered. RESULTS: RMR was significantly associated with body weight(r = 0.732, P < 0.001), body height(r = 0.401,P = 0.008), BMI(r = 0.504, P < 0.001), waist circumference(r = 0.602, P < 0.001), mid-upper arm circumference(r = 0.417, P = 0.006), mid-upper arm muscle circumference(r = 0.344, P = 0.028), total body water(r = 0.339, P = 0.035), body temperature(r = 0.409, P = 0.007), smoking(P = 0.031), serum T4 levels(r = 0.331, P = 0.036), obstructive sleep apnoea syndrome(OSAS; P = 0.023), impaired glucose tolerance(IGT; P = 0.017) and impaired glycaemic status, including hyperinsulinism, IGT and diabetes mellitus(P = 0.003).CONCLUSION: Future research should be prompted to optimize the procedure of indirect calorimetry to achieve clinical benefits in obese subjects.
文摘BACKGROUND Malnutrition affects 20%to 50%of patients with cirrhosis.It may be associated with serious complications and has a direct impact on prognosis.Resting energy expenditure(REE)is an important parameter to guide the optimization of therapy and recovery of nutritional status in patients with cirrhosis.However,the REE of patients with cirrhosis is still unclear,casting doubt upon the optimal nutritional management approach.AIM To identify the best method that predicts the REE of cirrhotic patients,using indirect calorimetry(IC)as the gold standard.METHODS An observational study was performed on 90 patients with cirrhosis.REE was assessed by IC,bioelectrical impedance analysis(BIA),and predictive formulas,which were compared using Bland-Altman plots and the Student’s t-test.RESULTS REE values measured by IC(1607.72±257.4 kcal)differed significantly from those determined by all other methods(BIA:1790.48±352.1 kcal;Harris&Benedict equation:2373.54±254.9 kcal;IOM equation:1648.95±185.6 kcal;Cunningham equation:1764.29±246.2 kcal),except the Food and Agriculture Organization of the United Nations,World Health Organization,and United Nations University(FAO/WHO/UNU)(1616.07±214.6 kcal)and McArdle(1611.30±241.8 kcal)equations.We found no significant association when comparing IC and 24-h dietary recall among different Child-Pugh classes of cirrhosis.CONCLUSION The IOM and FAO/WHO/UNU equations have the best agreement with the CI.These results indicate a possibility of different tools for the clinical practice on cirrhotic patients.
文摘目的:通过比较肥胖青少年基础代谢率实测值与公式推测值的一致性,探讨以性别、年龄、身高和体重为主要参数的基础代谢率推测公式能否适用于中国肥胖青少年。方法:以66名中国肥胖青少年(男32人,女34人)为对象,晨起空腹进行相关人体测量,并采用便携式气体代谢分析仪测定受试者的基础代谢率,区分性别后分别比较采用Harris and Benedict公式、Schofield公式和Mifflin公式计算的基础代谢率与实测值的差异。结果:中国肥胖青少年基础代谢率采用Mifflin公式和Harris and Benedict公式的推测值与实测值相比,偏倚较小,Mifflin公式为-5.79 kcal/d(男)和-57.45 kcal/d(女),Harris and Benedict公式为-109.86 kcal/d(男)和-63.76 kcal/d(女),均在临床可接受的范围(-250 kcal/d,250 kcal/d)内。Harris and Benedict公式推测男女肥胖青少年基础代谢率的一致性界限分别为(男:-732.16 kcal/d,512.45 kcal/d)和(女:-595.01 kcal/d,467.49 kcal/d),Mifflin公式推测男女肥胖青少年基础代谢率的一致性界限分别为(男:-597.91 kcal/d,586.33 kcal/d)和(女:-603.01,531.84),均超出临床可接受范围。Schofield公式计算女性肥胖青少年基础代谢率的推测值与实测值相比,偏倚为-123.69 kcal/d,计算男性肥胖青少年基础代谢率的推测值与实测值的偏倚为-260.35 kcal/d,其一致性界限超出临床可接受范围。结论:Harris and Benedict公式、Schofield公式和Mifflin公式用于评估中国肥胖青少年基础代谢率时,其推测值与实测值的一致性界限均超出临床可接受范围,以上三个公式所得基础代谢率推测值与间接测热法实测值一致性较差,评估中国肥胖青少年基础代谢率的准确性不够。
文摘目的观察老年胃肠道肿瘤病人静息能量代谢(Resting Energy Expenditure,REE)的特点。方法选择老年(≥60岁)胃肠道肿瘤患者和非肿瘤患者(对照组)各60例,应用间接测热仪对其进行REE测定,根据MNA法评价营养状况,计算Harris-Benedict公式预测值。结果老年男性肿瘤患者REE较对照组低,且差异有统计学意义;H-B公式预测值明显高于REE测定值,差异有统计学意义;临床估计能量供给的经验值平均为REE测量值的1.5倍。结论老年胃肠道肿瘤患者静息能量消耗较非肿瘤患者有所下降,H-B公式法不能准确预测病人的能量消耗,经验估计值可能会造成过度喂养。
文摘间接测热法(indirect calorimetry,IC)是能量测定的金标准。通过分析呼吸中的气体来计算总能量消耗(total energy expenditure,TEE),其准确率高。本综述介绍了间接测热法的原理、临床应用及局限性,也强调了间接测热设备的使用要点,解释了测量结果的具体意义,以期临床上能更好使用间接测热设备。
文摘背景:SWA(Sense Wear Pro Armband)是一种由多种运动传感器所结合的体力活动能量消耗监控设备。其在近年来被广泛应用于体力活动能量消耗的研究中。目的:对SWA准确性、软件版本、佩戴时间、不同人群和不同体力活动水平等不同方面的应用情况进行汇总,期望能为今后SWA的使用提供一些实用性的参考。方法:检索2015年1月前公开发表于CNKI全文数据库及PubM ed文摘数据库的论文。文献筛选标准为:1在CNKI全文数据库中以"体力活动,Armband,能量消耗"为关键词进行搜索。2检索Pubmed文摘数据库、Web of Science数据库,关键词为"Physical activity,Sense Wear Pro Armband,Energy Expenditure,Review"。以发表在核心期刊者或SCI数据库收录者优先。结果与结论:双标水、间接测热法等方法为标准的校标研究显示,SWA具有较高的准确性,能有效评估日常体力活动的能量消耗。但在特殊情况下也存在一定的差异,例如不同的人群、运动强度等。与此同时,确定恰当的佩戴时间和数据统计时使用软件版本也是影响最终结果准确性的因素之一。SWA能准确预测体力活动能耗,但针对不同人群、运动强度等情况应有必要对SWA的计算公式进一步的进行改进。
