Dynamic Promotional Resource Allocation for Segment Specific and Spectrum Effect of Promotion for a Product Line Incorporating Repeat Purchase Behavior

Promotion is an essential element in the marketing mix. It is used by businesses to inform, influence and persuade customers to adopt the products and services they offer. Without promotion, business would be stagnant and lack substantial growth because the brands would have low visibility in the market. Moreover, today’s vast and assorted markets comprise of customers with different needs and varied behavior. So it is rarely possible for companies to satisfy all customers by treating them alike. Thus there arises a need to divide the market into segments having customers with similar traits/characteristics. After identifying appropriate market segments, firms can design differentiated promotional campaigns for each segment. At the same time there can be a mass market promotional campaign that reaches different segments with a fixed spectrum. Also since promotional effort resources are limited, one must use them judiciously. In this paper, we formulate mathematical programming problem under repeat purchase scenario, which optimally allocates mass promotional effort resources and differentiated promotional effort resources across the segments dynamically in order to maximize the overall sales obtained from multiple products of a product line under budgetary and minimum sales aspiration level constraint on each product under consideration in each segment. The planning horizon is divided into multi periods, the adoption pattern of each product in each segment is observed in every subinterval and accordingly promotional effort allocations are determined for the next period till we reach the end of planning period. The optimization model has been further extended to incorporate minimum aspiration level constraints on total sales for each product under consideration from all the segments taken together. The non linear programming problem so formulated is solved using differential evolution approach. A numerical example has been discussed to illustrate applicability of the model.

Popular Science Animation for the Future Intelligent Agricultural Ecology of Agricultural Products Innovation Design and Promotion

The form of agricultural products promotion is also constantly updated with the continuous development of science and technology in recent years.Intelligent agriculture gradually leads the scientific and technological process of agricultural products planting,production,promotion and other fields,making agricultural production more efficient and controllable.The use of popular science animation in the innovative design and promotion of agricultural products will help to drive the agricultural economy,conform to the current new situation,and improve the competitiveness of agricultural products with the help of scientific and technological strength and innovation consciousness in this environment.

Generation of glyceraldehyde-derived advanced glycation end-products in pancreatic cancer cells and the potential of tumor promotion

To determine the possibility that diabetes mellitus promotes pancreatic ductal adenocarcinoma via glyceraldehyde (GA)-derived advanced glycation-end products (GA-AGEs). METHODSPANC-1, a human pancreatic cancer cell line, was treated with 1-4 mmol/L GA for 24 h. The cell viability and intracellular GA-AGEs were measured by WST-8 assay and slot blotting. Moreover, immunostaining of PANC-1 cells with an anti-GA-AGE antibody was performed. Western blotting (WB) was used to analyze the molecular weight of GA-AGEs. Heat shock proteins 90α, 90β, 70, 27 and cleaved caspase-3 were analyzed by WB. In addition, PANC-1 cells were treated with GA-AGEs-bovine serum albumin (GA-AGEs-BSA), as a model of extracellular GA-AGEs, and proliferation of PANC-1 cells was measured. RESULTSIn PANC-1 cells, GA induced the production of GA-AGEs and cell death in a dose-dependent manner. PANC-1 cell viability was approximately 40% with a 2 mmol/L GA treatment and decreased to almost 0% with a 4 mmol/L GA treatment (each significant difference was P < 0.01). Cells treated with 2 and 4 mmol/L GA produced 6.4 and 21.2 μg/mg protein of GA-AGEs, respectively (P < 0.05 and P < 0.01). The dose-dependent production of some high-molecular-weight (HMW) complexes of HSP90β, HSP70, and HSP27 was observed following administration of GA. We considered HMW complexes to be dimers and trimers with GA-AGEs-mediated aggregation. Cleaved caspase-3 could not be detected with WB. Furthermore, 10 and 20 μg/mL GA-AGEs-BSA was 27% and 34% greater than that of control cells, respectively (P < 0.05 and P < 0.01). CONCLUSIONAlthough intracellular GA-AGEs induce pancreatic cancer cell death, their secretion and release may promote the proliferation of other pancreatic cancer cells.

Product Promotion Prediction Model Based on Evaluation Information

This paper mainly studies the impact of evaluation information on e-commerce platform on the future of products.Through natural language processing and rating,an evaluation model based on user rating and evaluation is defined to measure product quality.Among them,evaluations are differentiated:review sentiment coefficient(R)and review length(L).The evaluation model is:.In order to predict the future reputation of products,based on the above evaluation model,time series is used to rank the products studied.Each customer purchases the product through Markov chain model,so as to predict the probability of future word-of-mouth spread of the product.Use TOPSIS method to select monthly sales,stars and comment sentiment coefficient as indicators.The comprehensive measurement method based on text and score is determined to predict whether the product is successfully promoted.

DNA G-Quadruplexes as Targets for Natural Product Drug Discovery

DNA guanine(G)-quadruplexes(G4s)are unique secondary structures formed by two or more stacked Gtetrads in G-rich DNA sequences.These structures have been found to play a crucial role in highly transcribed genes,especially in cancer-related oncogenes,making them attractive targets for cancer therapeutics.Significantly,targeting oncogene promoter G4 structures has emerged as a promising strategy to address the challenge of undruggable and drug-resistant proteins,such as MYC,BCL2,KRAS,and EGFR.Natural products have long been an important source of drug discovery,particularly in the fields of cancer and infectious diseases.Noteworthy progress has recently been made in the discovery of naturally occurring DNA G4-targeting drugs.Numerous DNA G4s,such as MYC-G4,BCL2-G4,KRAS-G4,PDGFR-b-G4,VEGF-G4,and telomeric-G4,have been identified as potential targets of natural products,including berberine,telomestatin,quindoline,sanguinarine,isaindigotone,and many others.Herein,we summarize and evaluate recent advancements in natural and nature-derived DNA G4 binders,focusing on understanding the structural recognition of DNA G4s by small molecules derived from nature.We also discuss the challenges and opportunities associated with developing drugs that target DNA G4s.

Research Progress on the Growth-Promoting Effect of Plant Biostimulants on Crops

A Plant Biostimulant is any substance or microorganism applied to plants to enhance nutrition efficiency,abioticstress tolerance,and/or crop quality traits,regardless of its nutrient content.The application of Plant biostimulants(PBs)in production can reduce the application of traditional pesticides and chemical fertilizers and improvethe quality and yield of crops,which is conducive to the sustainable development of agriculture.An in-depthunderstanding of the mechanism and effect of various PBs is very important for how to apply PBs reasonablyand effectively in the practice of crop production.This paper summarizes the main classification of PBs;Thegrowth promotion mechanism of PBs was analyzed from four aspects:improving soil physical and chemical properties,enhancing crop nutrient absorption capacity,photosynthesis capacity,and abiotic stress tolerance;At thesame time,the effects of PBs application on seed germination,seedling vigor,crop yield,and quality were summarized;Finally,how to continue to explore and study the use and mechanism of PBs in the future is analyzedand prospected,to better guide the application of PBs in crop production in the future.

DEVELOP SERIES PRODUCTS OF ROBOTS TO PROMOTE THE TECHNOLOGICAL ADVANCEMENT OF THE MANUFACTURING INDUSTRY

As a typical representative and main technicalmeans of advanced manufacturing technology,robotic technology plays an important role in raisingan enterpse’s engineering level, improving its prod-uct quality and productivity, and realizing civilizedproduction. Currently, there are nearly one millionrobots of various kinds, which are employed widelyin different fields of manufacturing industry. Robot-ics is now one of the high technologies, which arecompetitively developed by the developed coun-

Exploration into the Development of"Integration of Production and Education"in Vocational Education in China

In order to further clarify the function and important value of the integration of production and education for the development of vocational education,this paper combed the development context of the integration of production and education in China's vocational education from three dimensions:policy evolution,research evolution and practice promotion.Studies have shown that the integration of production and education,as a distinctive type characteristic of vocational education in China,has experienced four stages of evolution in policy:the period of combination of production and education,the preparation and presentation period,the full implementation period and the in-depth promotion period,and the initially-constructed institutional system reflects developmental characteristics.In academic research,there are obvious policy-driven characteristics.The theoretical framework tends to be perfect,and the concept connotation and promotion path are gradually getting clear,but the research on regional promotion modes is slightly insufficient.The empirical research is weak,and the operability of countermeasure research is not strong.Moreover,the problem of discussing integration based on education is more prominent.In practice and promotion,the characteristic of the integration of production and education is gradually highlighted and deepened in terms of talent training,school-running system and school-running mode,and the carriers and contents of the integration of production and education are gradually enriched.

A Three-Stage Stochastic Dynamic Pricing Game Model Affected by New Products into the Market

In real-life marketing, a common phenomenon is that the prices of current product will have been cut down even the new product has not gone into market yet. Thus, it is very important for merchant to set the strategy which can make the excepted revenue maximum. So, this paper constructs a three-stage stochastic dynamic pricing game model for analyzing the influence of the uncertainty of entry timing of the new products on pricing of products being sold. By analyzing of the pricing strategy, there are big differences in the predictions of new product going into market between merchant and customers;the merchant will adopt cutting price for promotion strategy to reduce negative influence of the new products on the demand of the products sold now. Otherwise, the merchant will adopt the strategy of maximizing current period’s profit.

CO2 residual concentration of potassium-promoted hydrotalcite for deep CO/CO2 purification in H2-rich gas

Elevated-temperature pressure swing adsorption is a promising technique for producing high purity hydrogen and controlling greenhouse gas emissions. Thermodynamic analysis indicated that the CO in H-rich gas could be controlled to trace levels of below 10 ppm by in situ reduction of the COconcentration to less than 100 ppm via the aforementioned process. The COadsorption capacity of potassiumpromoted hydrotalcite at elevated temperatures under different adsorption（mole fraction, working pressure） and desorption（flow rate, desorption time, steam effects） conditions was systematically investigated using a fixed bed reactor. It was found that the COresidual concentration before the breakthrough of COmainly depended on the total amount of purge gas and the COmole fraction in the inlet syngas.The residual COconcentration and uptake achieved for the inlet gas comprising CO（9.7 mL/min） and He（277.6 mL/min） at a working pressure of 3 MPa after 1 h of Ar purging at 300 mL/min were 12.3 ppm and0.341 mmol/g, respectively. Steam purge could greatly improve the cyclic adsorption working capacity, but had no obvious benefit for the recovery of the residual COconcentration compared to purging with an inert gas. The residual COconcentration obtained with the adsorbent could be reduced to 3.2 ppm after 12 h of temperature swing at 450 °C. A new concept based on an adsorption/desorption process, comprising adsorption, steam rinse, depressurization, steam purge, pressurization, and high-temperature steam purge, was proposed for reducing the steam consumption during CO/COpurification.

地方保护政策对中国新能源汽车市场推广的影响分析

加快建设全国统一大市场对推动中国新能源汽车产业发展具有重要意义,而各地频发的地方保护现象却成为阻碍新能源汽车市场推广的主要因素。以2010—2021年中国28个省(市、区)新能源汽车推广数量的面板数据作为研究样本,分析了地方保护政策对新能源汽车市场规模和市场占比的影响,以及产品市场发育程度在其中的调节和门槛效应。研究结果表明,地方保护政策对新能源汽车市场规模扩大和市场占比提升均有显著的抑制作用,产品市场发育程度在该影响过程中具有调节性作用,地方保护政策对市场规模的作用受到产品市场发育程度单一门槛效应的影响,而对市场占比的作用则受双重门槛效应的影响,呈现出先促进后抑制的倒“U”型特征。进一步研究显示,地方保护政策通过加深能源市场分割阻碍了新能源汽车市场推广。区域异质性表明,东部地区的地方保护政策对新能源汽车市场推广有显著的抑制作用,而中西部地区的保护政策则有助于市场规模的扩大;在有新能源汽车上市企业母公司的地区,地方保护政策的抑制作用更为明显;而在没有此类企业的地区,其抑制作用相对较弱。研究结论为打破中国新能源汽车产业中的地方保护主义、推动产业可持续发展提供了决策参考。

Production-teaching-research of a Commercial Aircraft Corporation in the Chinese Industry Chain

For the future development of a commercial aircraft corporation, this paper focused on the research and technological innovation model in an industrial chain and explored how to promote the sustainable development of technological innovation on the basis of the Chinese aviation industry. It puts forward several ways to reinforce cooperation, such as strengthening policies and regulations, government＇s support for research cooperations, accelerating construction of the production-teaching-research oriented public technology platform and service system, and firming the industry awareness of universities and research institutes, and so on.

促销之名,推销之实? 新产品促销性脱销的消费者相似品推荐反应

通过各种各样的促销手段促进新产品的动销与扩散已成为全球众多厂商惯用的营销策略,但促销也经常会导致新产品出现难以预料的脱销,为此厂商会积极给消费者推荐相似品。然而,现有研究却对此鲜有关注。基于信息加工理论(质量推断理论)与保护动机理论(诱导转向理论),本文通过构建一个有调节的双中介模型深入探究新产品促销性脱销是否、如何以及何时会影响消费者相似品推荐反应,并通过实验法对其进行了实证检验。研究结果表明:(1)新产品促销性脱销并不一定会产生“相似品替代效应”,而是会消极影响消费者相似品推荐反应,并且折扣性脱销较之于赠礼性脱销的影响更大;(2)质量推断与诱导转向会共同完全中介新产品促销性脱销对消费者相似品推荐反应的影响;(3)消费者的认知需求会对质量推断与诱导转向双中介效应发挥重要的调节作用。本文研究结论不仅能有效促进新产品脱销理论、销售促销理论、虚位诱导效应等理论体系的丰富和完善,而且对于厂商、消费者和监管机构等也有重要的管理启示。

陕南生态产品价值实现的区域合作困境与突破策略

陕南作为我国“南水北调”中线工程水源涵养地和秦巴生物资源多样性保护区,是重要的生态产品价值实现试验示范区。当前,区域合作对陕南生态产品价值实现十分必要。面对地方政府合作意愿与能力不足、生态产品相关标准体系残缺混乱、区域生态资本化运营能力薄弱、产品经营开发机制碎片化等现实困境,陕南生态产品价值实现应以生态资源区域化整合打造产品稀缺性、以区域生态资本化运营推动产品价值转化增值、以体制机制创新提升区域合作动力、以系统经营开发提升区域运营效率。针对当前所面临的困境,从生态产品价值实现的路径出发,提高地方政府合作意愿与能力,健全完善生态产品价值实现相关标准体系,提高生态资本化运营的整体能力,系统构建价值实现的经营开发机制将是推进陕南地区生态产品价值实现区域合作的努力方向。

数字时代语言文字发展的创新路径——人造语言的新质生产力研究

人造语言已有超过1000年的发展历史,至今已有一千多种人造语言出现在宗教、音乐、文学、影视、动漫、游戏等领域。人造语言不仅是社会文化产品,也是信息交流、身份构建和价值观对外传播的载体。数字智能时代背景下,人造语言的社会和市场属性日益凸显。如何突破传统的语言传播模式,打造语言文化走出去的新高地,是数字时代语言生活研究面临的机遇与挑战。目前人造语言尚未得到语言学界的足够重视,有必要梳理人造语言的概念、分类和造字机制。通过分析人造语言与文化、科技的互动关系,尝试从语言推广、知识生产和象征符号建设3方面探讨如何将数字时代人造语言的研究纳入新质生产力的建设内容,打造语言学新的增长点,为中华语言文化的国际推广提供增效赋能的突破口。

城门失火,殃及池鱼?新产品促销性脱销的相似品贬值效应

虽然新产品促销性脱销导致其暂时性缺货,会给相似品提供了替代和涨价的机会,但是新产品促销性脱销也会对相似品产生拖累效应,导致消费者对其评价降低。但目前相关的关注和研究较为匮乏。基于前景理论与控制动机理论,通过构建有调节的双中介模型,文章深入探寻了新产品促销性脱销影响相似品贬值的内在机理与边界条件,并且通过实验方法进行了实证检验。通过3个实验,结果发现:(1)新产品促销性脱销确实会让相似品产生贬值,并且价格促销性脱销较之于非价格促销性脱销更容易让相似品产生更大的贬值;(2)参照依赖与控制剥夺会共同中介新产品促销性脱销对相似品贬值的影响,其中前者起着消极中介效应,而后者起着积极中介效应;(3)消费者权力感(包括特质权力感与状态权力感)会调节参照依赖与控制剥夺的双中介效应,低权力感者更容易让参照依赖中介效应占优,而高权力感者更容易让控制剥夺中介效应占优。这些研究结论不仅对丰富和完善新产品促销、产品稀缺效应、虚位诱导效应等理论具有重要的意义,而且对指导和改善厂商的新产品营销、消费者理性看待新产品促销性脱销和监管机构的市场监管有重要的管理启示。

东北全面振兴的新质生产力实践研究

2023年9月,习近平总书记在黑龙江视察提出发展新质生产力,为东北全面振兴指明了新方向。习近平总书记关注东北振兴,在三次视察东北时不断地提出东北振兴的新思路、新对策,最终聚焦到发展新质生产力,呈现出一个脉络清晰、循序渐进的振兴东北新路径。深刻领会习近平总书记三次视察东北重要讲话精神,可以发现东北地区发展新质生产力必须遵循的实践路径,具体要做到“四个聚焦”、完成“六大任务”、进一步夯实“五大安全”。东北地区发展新质生产力,不仅需要自身高质量发展,而且必须在全国一盘棋下发挥好发展新质生产力的功能。

发展新质生产力的财税法促进

发展新质生产力对于推动高质量发展、提高人民生活福祉、实现中国式现代化意义十分重大。作为以调整财税关系和解决财税问题为己任的发展促进法,我国财税法对于发展新质生产力具有重要的促进作用。财税体制改革、财税法制度的完善,能为发展新质生产力营造良好的财税法治环境并提供有力的制度保障。财税法从科技创新、产业创新、发展方式创新、体制机制创新和人才工作机制创新等五个方面着力促进新质生产力发展。对照发展新质生产力的要求,我国财税法应就自身体系进行改革和创新:一是明确发展新质生产力背景下财税法革新的基本思路,强化财税法的发展促进理念与功能,以新一轮财税体制改革为契机推进财税法治建设;二是以发展功能为导向,进一步完善预算法律制度;三是高质量全面落实税收法定原则,完善税法体系;四是在发展和改革进程中推进政府间财政关系法治化。

新媒体背景下饲料产品的广告宣传策略

数字技术改变了人们的生活、学习和工作方式。其中,新媒体展现了个性化、实时性、受众面广、交互性强、内容丰富多样等特点,备受年轻用户的青睐。面对新媒体的海量用户群体,越来越多的企业选择在新媒体中开展广告宣传,饲料企业也不例外。从作用来看,新媒体广告宣传不仅能丰富宣传渠道,降低运营成本,而且能提高饲料产品的知名度。为此,饲料企业要借助新媒体的影响力,不断完善饲料产品的广告宣传策略,从而为饲料产品的促销及饲料企业的可持续发展奠定基础。

数字孪生技术驱动下的图书馆阅读推广服务场景研究

数字孪生技术是图书馆发展应用新质生产力、迈向业务数字化转型的有效途径。依托数字孪生创建虚拟场景,以虚控实、虚实融合,可以实时优化阅读推广方案,有效提升用户参与阅读推广活动的兴趣,实现阅读推广服务数字化转型。文章通过探索基于数字孪生的图书馆阅读推广技术基础、系统组成和应用架构,设计基于数字孪生的红色经典阅读推广场景推送方案,旨在为数字孪生在图书馆阅读推广服务中的实践应用提供思路。