The problem of excitation and the propagation of a nerve impulse by an axon (nerve fiber) for the case of a noninstantaneous function is studied. The application of no instantaneous step function of the Heaviside type...The problem of excitation and the propagation of a nerve impulse by an axon (nerve fiber) for the case of a noninstantaneous function is studied. The application of no instantaneous step function of the Heaviside type takes into account the time of delay. This generalizes the problem of the propagation of axon excitation to the case of an input impulse function’s noninstantaneous action with some increasing excitation. An exact analytical solution to the problem is constructed based on the Laplace integral transform and Ephros theorem. The propagation of the transmembrane potential was studied, in response to the switching on and off, for impulse of a constant current pulse delivered intracellularly at different points in time. The time analysis of excitation propagation along axon at different distances from the excitation point was performed.展开更多
文摘The problem of excitation and the propagation of a nerve impulse by an axon (nerve fiber) for the case of a noninstantaneous function is studied. The application of no instantaneous step function of the Heaviside type takes into account the time of delay. This generalizes the problem of the propagation of axon excitation to the case of an input impulse function’s noninstantaneous action with some increasing excitation. An exact analytical solution to the problem is constructed based on the Laplace integral transform and Ephros theorem. The propagation of the transmembrane potential was studied, in response to the switching on and off, for impulse of a constant current pulse delivered intracellularly at different points in time. The time analysis of excitation propagation along axon at different distances from the excitation point was performed.