PARK7/DJ-1 is a multifunctional protein that acts as a regulator in stress responsive cascades.Since its original discovery as a novel oncogene,DJ-1 was further implicated in the correspondingly dubbed PARK7 autosomal...PARK7/DJ-1 is a multifunctional protein that acts as a regulator in stress responsive cascades.Since its original discovery as a novel oncogene,DJ-1 was further implicated in the correspondingly dubbed PARK7 autosomal recessive early onset Parkinson’s Disease variant,expanding the spectrum of its pathophysiologyto neurodegenerative disease.展开更多
The breadth of the enrichment site for post-translational trimethylation of histone H3 at lysine 4 （H3K4me3） on chromatin has attracted great attention recently. H3K4me3, an extensively-studied histone modification,...The breadth of the enrichment site for post-translational trimethylation of histone H3 at lysine 4 （H3K4me3） on chromatin has attracted great attention recently. H3K4me3, an extensively-studied histone modification, is reported to promote gene transcription by directing preinitiation complex assembly through interaction with effector proteins, e.g.,展开更多
Subject Code:C14 With the support by the National Natural Science Foundation of China,the research team led by Prof.He Zuhua(何祖华)at the National Key Laboratory of Plant Molecular Genetics and National Center of Pla...Subject Code:C14 With the support by the National Natural Science Foundation of China,the research team led by Prof.He Zuhua(何祖华)at the National Key Laboratory of Plant Molecular Genetics and National Center of Plant Gene Research,Shanghai Institute of Plant Physiology&Ecology,Chinese Academy of Sciences,展开更多
文摘PARK7/DJ-1 is a multifunctional protein that acts as a regulator in stress responsive cascades.Since its original discovery as a novel oncogene,DJ-1 was further implicated in the correspondingly dubbed PARK7 autosomal recessive early onset Parkinson’s Disease variant,expanding the spectrum of its pathophysiologyto neurodegenerative disease.
基金supported by faculty start up funding provided by The Methodist Hospital Research Institute,Texas,United States
文摘The breadth of the enrichment site for post-translational trimethylation of histone H3 at lysine 4 （H3K4me3） on chromatin has attracted great attention recently. H3K4me3, an extensively-studied histone modification, is reported to promote gene transcription by directing preinitiation complex assembly through interaction with effector proteins, e.g.,
文摘Subject Code:C14 With the support by the National Natural Science Foundation of China,the research team led by Prof.He Zuhua(何祖华)at the National Key Laboratory of Plant Molecular Genetics and National Center of Plant Gene Research,Shanghai Institute of Plant Physiology&Ecology,Chinese Academy of Sciences,
