We demonstrate the spectroscopic and laser performance before and after 100 Mrad gamma-ray irradiation on an Er,Pr：GYSGG crystal grown by the Czochralski method. The additional absorption of Er,Pr：GYSGG crystal is c...We demonstrate the spectroscopic and laser performance before and after 100 Mrad gamma-ray irradiation on an Er,Pr：GYSGG crystal grown by the Czochralski method. The additional absorption of Er,Pr：GYSGG crystal is close to zero in the 968 nm pumping and 2.7-3 μm laser wavelength regions. The lifetimes of the upper and lower levels show faint decreases after gamma-ray irradiation. The maximum output powers of 542 and 526 mW with the slope efficiencies of 17.7% and 17.0% are obtained, respectively, on the GYSGG/Er,Pr：GYSGG composite crystal before and after the gammaray irradiation. These results suggest that Er,Pr：GYSGG crystal as a laser gain medium possesses a distinguished antiradiation ability for application in space and radiant environments.展开更多
Objective:To study the effect of Er, Cr: YSGG laser combined with oral basic treatment on inflammatory injury and apoptosis in patients with periodontitis.Methods: Patients with chronic periodontitis who were treated ...Objective:To study the effect of Er, Cr: YSGG laser combined with oral basic treatment on inflammatory injury and apoptosis in patients with periodontitis.Methods: Patients with chronic periodontitis who were treated in dental clinic of our hospital between February 2015 and March 2017 were selected as the research subjects and randomly divided into the group A who accepted ultrasonic dental cleaning, hand scaling combined with Er, Cr: YSGG laser treatment and the group B who received ultrasonic dental cleaning and hand scaling treatment. The contents of inflammatory response cytokines, protease molecules and apoptosis molecules in gingival crevicular fluid were detected before treatment and 1 week after treatment.Results:TNF-α, hs-CRP, IL-1β, IL-6, IL-8, EMMPRIN, CyPA, MMP2, MMP9, Smac, Bax, Fas and FasL contents in gingival crevicular fluid of both groups of patients 1 week after treatment were significantly lower than those before treatment, and TNF-α, hs-CRP, IL-1β, IL-6, IL-8, EMMPRIN, CyPA, MMP2, MMP9, Smac, Bax, Fas and FasL contents of group A 1 week after treatment were significantly lower than those of group B.Conclusion: Er, Cr: YSGG laser combined with oral basic treatment can inhibit the inflammatory injury and apoptosis in periodontal tissue of patients with periodontitis.展开更多
基金Project supported by the National Key Research and Development Program of China(Grant No.2016YFB1102301)the National Natural Science Foundation of China(Grant Nos.51272254,61405206,and 51502292)the Open Research Fund of the State Key Laboratory of Pulsed Power Laser Technology,Electronic Engineering Institute,China(Grant No.SKL2015KF01)
文摘We demonstrate the spectroscopic and laser performance before and after 100 Mrad gamma-ray irradiation on an Er,Pr：GYSGG crystal grown by the Czochralski method. The additional absorption of Er,Pr：GYSGG crystal is close to zero in the 968 nm pumping and 2.7-3 μm laser wavelength regions. The lifetimes of the upper and lower levels show faint decreases after gamma-ray irradiation. The maximum output powers of 542 and 526 mW with the slope efficiencies of 17.7% and 17.0% are obtained, respectively, on the GYSGG/Er,Pr：GYSGG composite crystal before and after the gammaray irradiation. These results suggest that Er,Pr：GYSGG crystal as a laser gain medium possesses a distinguished antiradiation ability for application in space and radiant environments.
文摘Objective:To study the effect of Er, Cr: YSGG laser combined with oral basic treatment on inflammatory injury and apoptosis in patients with periodontitis.Methods: Patients with chronic periodontitis who were treated in dental clinic of our hospital between February 2015 and March 2017 were selected as the research subjects and randomly divided into the group A who accepted ultrasonic dental cleaning, hand scaling combined with Er, Cr: YSGG laser treatment and the group B who received ultrasonic dental cleaning and hand scaling treatment. The contents of inflammatory response cytokines, protease molecules and apoptosis molecules in gingival crevicular fluid were detected before treatment and 1 week after treatment.Results:TNF-α, hs-CRP, IL-1β, IL-6, IL-8, EMMPRIN, CyPA, MMP2, MMP9, Smac, Bax, Fas and FasL contents in gingival crevicular fluid of both groups of patients 1 week after treatment were significantly lower than those before treatment, and TNF-α, hs-CRP, IL-1β, IL-6, IL-8, EMMPRIN, CyPA, MMP2, MMP9, Smac, Bax, Fas and FasL contents of group A 1 week after treatment were significantly lower than those of group B.Conclusion: Er, Cr: YSGG laser combined with oral basic treatment can inhibit the inflammatory injury and apoptosis in periodontal tissue of patients with periodontitis.
