Toll-like receptor(TLRs)is one of the important recognition receptors in the innate immune defense system,which plays a key role in mediating inflammatory response and related signal transduction.In the TLRs family,TL...Toll-like receptor(TLRs)is one of the important recognition receptors in the innate immune defense system,which plays a key role in mediating inflammatory response and related signal transduction.In the TLRs family,TLR2/4 has been widely studied because of its close relationship with the occurrence and defense of digestive diseases,and studies have shown that the synergism between TLR2/4 is the basis of mediating inflammatory response and immune response.This article summarizes the research on the correlation of TLR2/4 in digestive system diseases,in order to provide ideas for the clinical treatment and research of digestive system diseases.展开更多
基金National Natural Science Foundation of China(No.81660649)。
文摘Toll-like receptor(TLRs)is one of the important recognition receptors in the innate immune defense system,which plays a key role in mediating inflammatory response and related signal transduction.In the TLRs family,TLR2/4 has been widely studied because of its close relationship with the occurrence and defense of digestive diseases,and studies have shown that the synergism between TLR2/4 is the basis of mediating inflammatory response and immune response.This article summarizes the research on the correlation of TLR2/4 in digestive system diseases,in order to provide ideas for the clinical treatment and research of digestive system diseases.
