Squamous cell carcinoma of the esophagus (SCCE) carries a poor prognosis due to late diagnosis.Early detection is highly desirable,since surgical and endoscopic resection offers the only possible cure for esophageal c...Squamous cell carcinoma of the esophagus (SCCE) carries a poor prognosis due to late diagnosis.Early detection is highly desirable,since surgical and endoscopic resection offers the only possible cure for esophageal cancer.Population screening should be undertaken in high risk areas,and in low or moderate risk areas for people with risk factors (alcoholics,smokers,mate drinkers,history of head and neck cancer,achalasia and lye stricture of the esophagus).Esophageal balloon cytology is an easy and inexpensive sampling technique,but the current methods are insufficient for primary screening due to sampling errors.Conventional endoscopy with biopsy remains the standard procedure for the identification of pre-malignant and early malignant changes in esophageal mucosa and endoscopic detection.It may be enhanced by several techniques such as dye and optic chromoendoscopy,magnifying endoscopy,and optical-based spectroscopic and imaging modalities.Since more than 80% of SCCE deaths occur in developing countries,where expensive techniques such as narrow band imaging (NBI) and autofluorescence imaging are unavailable,the most cost-effective tool for targeting biopsies may be Lugol dye chromoendoscopy,since it is easy,accurate,inexpensive and available worldwide.In ideal conditions,or in developed countries,is it reasonable to think that optimal detection will require a combination of techniques,such as the combination of Lugol’s chromoendoscopy and NBI to identify esophageal areas that require further characterization by a high resolution technique.The efficacy and cost-effectiveness will determine whether these modalities will become part of standard endoscopy practice.展开更多
目的探讨维生素C注射液(VCS)脱碘对内镜下食管碘染色的老年病人舒适度及护理满意度的影响。方法利用随机数表法将2019年3~4月南京医科大学第一附属医院52例内镜下食管碘染色后脱碘处理的老年病人(>60岁),随机分为VCS组和生理盐水(NS)...目的探讨维生素C注射液(VCS)脱碘对内镜下食管碘染色的老年病人舒适度及护理满意度的影响。方法利用随机数表法将2019年3~4月南京医科大学第一附属医院52例内镜下食管碘染色后脱碘处理的老年病人(>60岁),随机分为VCS组和生理盐水(NS)组,每组26例。根据Bruggrmann舒适度评分制定舒适度评分表及简易护理满意度量表,对检查结束时和检查后30 min 2组病人的舒适度和护理满意度进行评分和比较分析。结果碘染后急性症状主要为胸骨后不适,迟发反应以上腹部不适为主。检查结束时VCS组的胸骨后不适发生率明显低于NS组(P=0.02);检查后30 min VCS组咽喉不适较NS组明显缓解(P=0.02)。VCS组护理满意度总评分、沟通与解释和专业水平评分均高于NS组(均P<0.05)。结论VCS脱碘能显著改善老年病人碘染后的胸骨后不适和咽喉部不适,提高护理满意度。展开更多
文摘Squamous cell carcinoma of the esophagus (SCCE) carries a poor prognosis due to late diagnosis.Early detection is highly desirable,since surgical and endoscopic resection offers the only possible cure for esophageal cancer.Population screening should be undertaken in high risk areas,and in low or moderate risk areas for people with risk factors (alcoholics,smokers,mate drinkers,history of head and neck cancer,achalasia and lye stricture of the esophagus).Esophageal balloon cytology is an easy and inexpensive sampling technique,but the current methods are insufficient for primary screening due to sampling errors.Conventional endoscopy with biopsy remains the standard procedure for the identification of pre-malignant and early malignant changes in esophageal mucosa and endoscopic detection.It may be enhanced by several techniques such as dye and optic chromoendoscopy,magnifying endoscopy,and optical-based spectroscopic and imaging modalities.Since more than 80% of SCCE deaths occur in developing countries,where expensive techniques such as narrow band imaging (NBI) and autofluorescence imaging are unavailable,the most cost-effective tool for targeting biopsies may be Lugol dye chromoendoscopy,since it is easy,accurate,inexpensive and available worldwide.In ideal conditions,or in developed countries,is it reasonable to think that optimal detection will require a combination of techniques,such as the combination of Lugol’s chromoendoscopy and NBI to identify esophageal areas that require further characterization by a high resolution technique.The efficacy and cost-effectiveness will determine whether these modalities will become part of standard endoscopy practice.
文摘目的探讨维生素C注射液(VCS)脱碘对内镜下食管碘染色的老年病人舒适度及护理满意度的影响。方法利用随机数表法将2019年3~4月南京医科大学第一附属医院52例内镜下食管碘染色后脱碘处理的老年病人(>60岁),随机分为VCS组和生理盐水(NS)组,每组26例。根据Bruggrmann舒适度评分制定舒适度评分表及简易护理满意度量表,对检查结束时和检查后30 min 2组病人的舒适度和护理满意度进行评分和比较分析。结果碘染后急性症状主要为胸骨后不适,迟发反应以上腹部不适为主。检查结束时VCS组的胸骨后不适发生率明显低于NS组(P=0.02);检查后30 min VCS组咽喉不适较NS组明显缓解(P=0.02)。VCS组护理满意度总评分、沟通与解释和专业水平评分均高于NS组(均P<0.05)。结论VCS脱碘能显著改善老年病人碘染后的胸骨后不适和咽喉部不适,提高护理满意度。
