Objective:To evaluate in ritro antimicrobial activities of selected 58 ethno-medicinal plant extracts with a view to assess their therapeutic potential.Methods:A total of 58 traditional Chinese medicinal plants were c...Objective:To evaluate in ritro antimicrobial activities of selected 58 ethno-medicinal plant extracts with a view to assess their therapeutic potential.Methods:A total of 58 traditional Chinese medicinal plants were carefully selected based on the literature review and their traditional use.The antimicrobial activities of ethanol extracts of these medicinal plants were tested against fungi(Aspergillus funigaius),yeast(Candida albicans),gram-negative(Acirelobacter haumannii and Pseudornnruis aeruginosa)and gram-positive bacteria(Staphglococcus aureus).The activities were tested at three different concentrations of 1.00,0.10 and 0.01 mg/mL.The data was analysed using Gene data Screener program.Results:The measured antimicrobial activities indicated that out of the 58 plant extracts,15 extracts showed anti-fungal activity and 23 extracts exhibited anti-bacterial activity.Eight plant extracts have exhibited both anti-bacterial and anti-fungal activities.For instance,Eucommia ulmoides,Pohgonum cuspidcrtum,Poria cocas and Uncaria rhineophylla showed activity against both bacterial and fungal strains,indicating their broad spectrum of activity.Conclusions:The results revealed that the ethanol extracts of 30 plants out of the selected 58 possess significant antimicrobial activities.It is interesting to note that the findings from the current study are consistent with the traditional use.A clear correlation has also been found between the antimicrobial activity and the flavonoid content of the plant extracts which is in agreement with the literature.Hence.the results presented here can be used to guide the selection of potential plant species for the isolation and structure elucidation of novel antimicrobial compounds in order to establish the structure-activity relationship.This in turn is expected to lead the way to the discovery of novel antimicrobial agents for therapeutic use.展开更多
The antifungal activity of ethanol and acetone extract of leaves of nine medicinal plants: Piper betel, Lowsonia inermis, Psidium guajava, Carica papaya, Moringa oleifera, Mimosa pudica, Catharanthus roseus, Adhatoda ...The antifungal activity of ethanol and acetone extract of leaves of nine medicinal plants: Piper betel, Lowsonia inermis, Psidium guajava, Carica papaya, Moringa oleifera, Mimosa pudica, Catharanthus roseus, Adhatoda vasica and Andrographis paniculata against Fusarium oxysporum the causal agent of Fusarium wilt in tomato was assessed. All the extracts inhibited mycellial growth at various levels. Among them the superior inhibition (100%) was found in 15% concentration of ethanol extract of Lowsonia inermis and Psidium guajava against Fusarium. In all plant extract there were no significant differences between 20% and 25% concentration, except Piper betel, Carica papaya, Andrographis paniculata and Lawsonia inermis. Analysis of variance results on mycelial growth in different concentration shows that the item was highly significant.展开更多
基金funded by the University of Western Sydney and the Fundacion MEDINAa public-private partnership of Merck Sharp&Dohme de Espana S.A./Universidad de Granada/Junta de Andalucia
文摘Objective:To evaluate in ritro antimicrobial activities of selected 58 ethno-medicinal plant extracts with a view to assess their therapeutic potential.Methods:A total of 58 traditional Chinese medicinal plants were carefully selected based on the literature review and their traditional use.The antimicrobial activities of ethanol extracts of these medicinal plants were tested against fungi(Aspergillus funigaius),yeast(Candida albicans),gram-negative(Acirelobacter haumannii and Pseudornnruis aeruginosa)and gram-positive bacteria(Staphglococcus aureus).The activities were tested at three different concentrations of 1.00,0.10 and 0.01 mg/mL.The data was analysed using Gene data Screener program.Results:The measured antimicrobial activities indicated that out of the 58 plant extracts,15 extracts showed anti-fungal activity and 23 extracts exhibited anti-bacterial activity.Eight plant extracts have exhibited both anti-bacterial and anti-fungal activities.For instance,Eucommia ulmoides,Pohgonum cuspidcrtum,Poria cocas and Uncaria rhineophylla showed activity against both bacterial and fungal strains,indicating their broad spectrum of activity.Conclusions:The results revealed that the ethanol extracts of 30 plants out of the selected 58 possess significant antimicrobial activities.It is interesting to note that the findings from the current study are consistent with the traditional use.A clear correlation has also been found between the antimicrobial activity and the flavonoid content of the plant extracts which is in agreement with the literature.Hence.the results presented here can be used to guide the selection of potential plant species for the isolation and structure elucidation of novel antimicrobial compounds in order to establish the structure-activity relationship.This in turn is expected to lead the way to the discovery of novel antimicrobial agents for therapeutic use.
文摘The antifungal activity of ethanol and acetone extract of leaves of nine medicinal plants: Piper betel, Lowsonia inermis, Psidium guajava, Carica papaya, Moringa oleifera, Mimosa pudica, Catharanthus roseus, Adhatoda vasica and Andrographis paniculata against Fusarium oxysporum the causal agent of Fusarium wilt in tomato was assessed. All the extracts inhibited mycellial growth at various levels. Among them the superior inhibition (100%) was found in 15% concentration of ethanol extract of Lowsonia inermis and Psidium guajava against Fusarium. In all plant extract there were no significant differences between 20% and 25% concentration, except Piper betel, Carica papaya, Andrographis paniculata and Lawsonia inermis. Analysis of variance results on mycelial growth in different concentration shows that the item was highly significant.
