Objective： To investigate the action mechanism of acupuncture for non-insulin resistant polycystic ovary syndrome （PCOS）. Methods： A total of 46 cases with non-insulin resistant PCOS were randomly allocated into a...Objective： To investigate the action mechanism of acupuncture for non-insulin resistant polycystic ovary syndrome （PCOS）. Methods： A total of 46 cases with non-insulin resistant PCOS were randomly allocated into an observation group of 23 cases and a control group of 23 cases. Cases in the observation group were treated by needling bilateral Weiwanxiashu （Ex-B 3）, whereas those in the control group were treated by needling bilateral Sanyinjiao （SP 6）. After 3-month treatments, a comparison was made on the changes of ovulations rates, Follicle-stimulating hormone （FSH）, luteinizing hormone （LH）, testosterone （T）, fasting insulin and body mass index （BMI）. Results： There were statistical differences in ovulation rates and LH/FSH before and after the treatment in the observation group （P〈0.05）, along with a statistical difference in testosterone changes （P〈0.01）. There were also statistical differences in LH and LH/FSH before and after the treatment in the control group （P〉0.05）; however, there were no statistical differences in ovulation rates and testosterone changes （P〈0.05）. There was significant difference in testosterone changes between the two groups after the treatment （P〈0.01）, along with a statistical difference in ovulation rates between the two groups （P〈0.05）. However, there were no statistical differences in LH/FSH and BMI between the two groups. Conclusion： Needling Weiwanxiashu （Ex-B 3） and Sanyinjiao （SP 6） can both improve the endocrine disorder of patients with non-insulin resistant PCOS; however, needling Weiwanxiashu （Ex-B 3） can obtain a better result than Sanyinjiao （SP 6） in increasing the insulin sensitivity and preventing insulin resistance.展开更多
文摘Objective： To investigate the action mechanism of acupuncture for non-insulin resistant polycystic ovary syndrome （PCOS）. Methods： A total of 46 cases with non-insulin resistant PCOS were randomly allocated into an observation group of 23 cases and a control group of 23 cases. Cases in the observation group were treated by needling bilateral Weiwanxiashu （Ex-B 3）, whereas those in the control group were treated by needling bilateral Sanyinjiao （SP 6）. After 3-month treatments, a comparison was made on the changes of ovulations rates, Follicle-stimulating hormone （FSH）, luteinizing hormone （LH）, testosterone （T）, fasting insulin and body mass index （BMI）. Results： There were statistical differences in ovulation rates and LH/FSH before and after the treatment in the observation group （P〈0.05）, along with a statistical difference in testosterone changes （P〈0.01）. There were also statistical differences in LH and LH/FSH before and after the treatment in the control group （P〉0.05）; however, there were no statistical differences in ovulation rates and testosterone changes （P〈0.05）. There was significant difference in testosterone changes between the two groups after the treatment （P〈0.01）, along with a statistical difference in ovulation rates between the two groups （P〈0.05）. However, there were no statistical differences in LH/FSH and BMI between the two groups. Conclusion： Needling Weiwanxiashu （Ex-B 3） and Sanyinjiao （SP 6） can both improve the endocrine disorder of patients with non-insulin resistant PCOS; however, needling Weiwanxiashu （Ex-B 3） can obtain a better result than Sanyinjiao （SP 6） in increasing the insulin sensitivity and preventing insulin resistance.
