BACKGROUND The recurrence rate of liver cancer after surgery is high.Radiofrequency ablation(RFA)combined with transcatheter arterial chemoembolization(TACE)is an effective treatment for liver cancer;however,its effic...BACKGROUND The recurrence rate of liver cancer after surgery is high.Radiofrequency ablation(RFA)combined with transcatheter arterial chemoembolization(TACE)is an effective treatment for liver cancer;however,its efficacy in recurrent liver cancer remains unclear.AIM To investigate the clinical effect of TACE combined with RFA in the treatment of recurrent liver cancer.METHODS Ninety patients with recurrent liver cancer were divided into 2 groups according to treatment plan:Control(RFA alone);and experimental[TACE combined with RFA(TACE+RFA)].The incidence of increased alanine aminotransferase levels,complications,and other indices were compared between the two groups before and after the procedures.RESULTS One month after the procedures,the short-term efficacy rate and Karnofsky Performance Status scores of the experimental group were significantly higher than those of the control group(P<0.05).Alpha-fetoprotein(AFP)and total bilirubin levels were lower than those in the control group(P<0.05);The overall response rate was 82.22%and 66.67%in the experimental and control groups,respectively;The disease control rate was 93.33%and 82.22%in the experimental and control groups,respectively,the differences are statistically significant(P<0.05).And there were no statistical differences in complications between the two groups(P>0.05).CONCLUSION TACE+RFA was effective for the treatment of recurrent liver cancer and significantly reduced AFP levels and improved various indices of liver function.展开更多
目的观察5-氟尿嘧啶节律性化疗对晚期胃癌患者的临床疗效。方法选择我院24例晚期胃癌患者,使用5-氟尿嘧啶500 mg静脉持续泵入12 h d1-21,4周1个疗程,3～9个疗程后,对接受至少3个疗程的患者进行疗效评价。结果 24例患者随访8～24个月,3...目的观察5-氟尿嘧啶节律性化疗对晚期胃癌患者的临床疗效。方法选择我院24例晚期胃癌患者,使用5-氟尿嘧啶500 mg静脉持续泵入12 h d1-21,4周1个疗程,3～9个疗程后,对接受至少3个疗程的患者进行疗效评价。结果 24例患者随访8～24个月,3例部分缓解(12.5%),9例病情稳定(37.5%),无1例患者完全缓解,12例患者病情进展(50.0%),疾病控制率为50.0%。治疗有效患者的中位疾病进展时间(TTP)为3.2个月。结论 5-氟尿嘧啶节律性化疗可以有效控制老年晚期胃癌患者的病情进展,不良反应少且轻。展开更多
目的分析对二甲双胍失效的2型糖尿病(diabetes mellitus type 2,T2DM)患者接受利拉鲁肽治疗对患者血糖(blood glucose,Glu)和体质量的影响。方法选取2019年8月—2021年8月山东国欣颐养集团枣庄中心医院诊治的60例单一二甲双胍治疗失效T...目的分析对二甲双胍失效的2型糖尿病(diabetes mellitus type 2,T2DM)患者接受利拉鲁肽治疗对患者血糖(blood glucose,Glu)和体质量的影响。方法选取2019年8月—2021年8月山东国欣颐养集团枣庄中心医院诊治的60例单一二甲双胍治疗失效T2DM患者为研究对象,通过随机掷骰子法将其分为比对组、研究组,每组30例。比对组患者给予胰岛素给药治疗;研究组加用利拉鲁肽配合治疗。对比两组患者治疗前后的临床指标变化情况及疗效优良率。结果治疗前,两组患者的临床指标对比,差异无统计学意义(P>0.05);治疗后,两组患者的临床指标均有所改善,且研究组患者的临床指标优于比对组,差异有统计学意义(P<0.05);研究组患者的疗效优良率(96.67%)高于比对组(73.33%),差异有统计学意义(χ^(2)=4.705,P=0.030)。结论利拉鲁肽治疗二甲双胍治疗失效T2DM可以稳定患者的指标,更有利于长期给药控制Glu及体质量。展开更多
目的:探讨品管圈(Qualitycontrol circle, QCC)在外科重症监护病房(Surgicalintensive care unit, SICU)护士临床护理工作中的应用效果。方法:由9名SICU护士成立品管圈,选取2018年10月至2019年3月未采取品管圈护理管理模式,2019年4月至2...目的:探讨品管圈(Qualitycontrol circle, QCC)在外科重症监护病房(Surgicalintensive care unit, SICU)护士临床护理工作中的应用效果。方法:由9名SICU护士成立品管圈,选取2018年10月至2019年3月未采取品管圈护理管理模式,2019年4月至2019年8月采取品管圈护理管理模式,比较品管圈管理前后SICU护士病情知晓率、临床素养评分、综合素质评价及护理服务满意度。结果:开展QCC活动后SICU护士对患者病情知晓率从56.5%提高至82.5%,具有统计学差异(P P P 【0.05);QCC运用手法、活动信心、责任荣誉感、脑力开发、团体精神及和谐沟通6个方面得到显著提高。结论:将QCC活动应用于SICU护理中,可显著提高护理工作质量及护理服务满意度,值得临床护理工作中推广。展开更多
文摘BACKGROUND The recurrence rate of liver cancer after surgery is high.Radiofrequency ablation(RFA)combined with transcatheter arterial chemoembolization(TACE)is an effective treatment for liver cancer;however,its efficacy in recurrent liver cancer remains unclear.AIM To investigate the clinical effect of TACE combined with RFA in the treatment of recurrent liver cancer.METHODS Ninety patients with recurrent liver cancer were divided into 2 groups according to treatment plan:Control(RFA alone);and experimental[TACE combined with RFA(TACE+RFA)].The incidence of increased alanine aminotransferase levels,complications,and other indices were compared between the two groups before and after the procedures.RESULTS One month after the procedures,the short-term efficacy rate and Karnofsky Performance Status scores of the experimental group were significantly higher than those of the control group(P<0.05).Alpha-fetoprotein(AFP)and total bilirubin levels were lower than those in the control group(P<0.05);The overall response rate was 82.22%and 66.67%in the experimental and control groups,respectively;The disease control rate was 93.33%and 82.22%in the experimental and control groups,respectively,the differences are statistically significant(P<0.05).And there were no statistical differences in complications between the two groups(P>0.05).CONCLUSION TACE+RFA was effective for the treatment of recurrent liver cancer and significantly reduced AFP levels and improved various indices of liver function.
文摘目的分析对二甲双胍失效的2型糖尿病(diabetes mellitus type 2,T2DM)患者接受利拉鲁肽治疗对患者血糖(blood glucose,Glu)和体质量的影响。方法选取2019年8月—2021年8月山东国欣颐养集团枣庄中心医院诊治的60例单一二甲双胍治疗失效T2DM患者为研究对象,通过随机掷骰子法将其分为比对组、研究组,每组30例。比对组患者给予胰岛素给药治疗;研究组加用利拉鲁肽配合治疗。对比两组患者治疗前后的临床指标变化情况及疗效优良率。结果治疗前,两组患者的临床指标对比,差异无统计学意义(P>0.05);治疗后,两组患者的临床指标均有所改善,且研究组患者的临床指标优于比对组,差异有统计学意义(P<0.05);研究组患者的疗效优良率(96.67%)高于比对组(73.33%),差异有统计学意义(χ^(2)=4.705,P=0.030)。结论利拉鲁肽治疗二甲双胍治疗失效T2DM可以稳定患者的指标,更有利于长期给药控制Glu及体质量。
文摘目的:探讨品管圈(Qualitycontrol circle, QCC)在外科重症监护病房(Surgicalintensive care unit, SICU)护士临床护理工作中的应用效果。方法:由9名SICU护士成立品管圈,选取2018年10月至2019年3月未采取品管圈护理管理模式,2019年4月至2019年8月采取品管圈护理管理模式,比较品管圈管理前后SICU护士病情知晓率、临床素养评分、综合素质评价及护理服务满意度。结果:开展QCC活动后SICU护士对患者病情知晓率从56.5%提高至82.5%,具有统计学差异(P P P 【0.05);QCC运用手法、活动信心、责任荣誉感、脑力开发、团体精神及和谐沟通6个方面得到显著提高。结论:将QCC活动应用于SICU护理中,可显著提高护理工作质量及护理服务满意度,值得临床护理工作中推广。
