Mental fatigue is a complex state that results from prolonged cognitive activity. Symptoms of mental fatigue can include change in mood, motivation, and temporary deterioration of various cognitive functions involved ...Mental fatigue is a complex state that results from prolonged cognitive activity. Symptoms of mental fatigue can include change in mood, motivation, and temporary deterioration of various cognitive functions involved in goal-directed behavior. Extensive research has been done to develop methods for recognizing physiological and psychophysiological signs of mental fatigue. This has allowed the development of many AI-based models to classify different levels of fatigue, using data extracted from eye-tracking device, EEG, or ECG. In this paper, we present an experimental protocol which aims to both generate/measure mental fatigue and provide effective strategies for recuperation via VR sessions paired with EEG and eye tracking devices. This paper first provides a comprehensive state-of-the-art of mental fatigue predictive factors, measurement methods, and recuperation strategies. Then the paper presents an experimental protocol resulting from the state-of-the-art to 1) generate and measure mental fatigue and 2) evaluate the effectiveness of virtual therapy for fatigue recuperation, using a virtual reality (VR) simulated environment. In our work, we successfully generated mental fatigue through completion of cognitive tasks in a virtual simulated environment. Participants showed significant decline in pupil diameter and theta/alpha score during the various cognitive tasks. We trained an RBF SVM classifier from Electroencephalogram (EEG) data classifying mental fatigue with 95% accuracy on the test set. Finally, our results show that the time allocated for virtual therapy did not improve pupil diameter in post-relaxation period. Further research on the impact of relaxation therapy on relaxation therapy should allocate time closer to the standard recovery time of 60 min.展开更多
To explore the mechanisms underlying exercise-induced local muscle fatigue in patients with idiopathic Parkinson's disease (PD),we used surface electromyography to record myoelectric signals from the tibialis anter...To explore the mechanisms underlying exercise-induced local muscle fatigue in patients with idiopathic Parkinson's disease (PD),we used surface electromyography to record myoelectric signals from the tibialis anterior muscle during isometric contraction-induced fatigue until exhaustion.The results revealed no significant differences between patients with idiopathic PD and healthy controls in maximum voluntary contraction of the tibialis anterior muscle.The basic characteristics of surface electromyography were also similar between the two groups.The duration of isometric contraction at 50% maximum voluntary contraction was shortened in PD patients.In addition,PD patients exhibited a stronger increase in mean square amplitude,but a weaker decrease in median frequency and mean power frequency compared with healthy controls during isometric contraction.The skeletal muscles of PD patients revealed specificity of surface electromyography findings,indicating increased fatigability compared with healthy controls.展开更多
Maintaining sustained attention during a prolonged cognitive task often comes at a cost: high levels of mental fatigue. Heuristically, mental fatigue refers to a feeling of tiredness or exhaustion, and a disengagement...Maintaining sustained attention during a prolonged cognitive task often comes at a cost: high levels of mental fatigue. Heuristically, mental fatigue refers to a feeling of tiredness or exhaustion, and a disengagement from the task at hand;it manifests as impaired cognitive and behavioral performance. In order to effectively reduce the undesirable yet preventable consequences of mental fatigue in many real-world workspaces, a better understanding of the underlying neural mechanisms is needed, and continuous efforts have been devoted to this topic. In comparison with conventional univariate approaches, which are widely utilized in fatigue studies, convergent evidence has shown that multivariate functional connectivity analysis may lead to richer information about mental fatigue. In fact, mental fatigue is increasingly thought to be related to the deviated reorganization of functional connectivity among brain regions in recent studies. In addition, graph theoretical analysis has shed new light on quantitatively assessing the reorganization of the brain functional networks that are modulated by mental fatigue. This review article begins with a brief introduction to neuroimaging studies on mental fatigue and the brain connectome, followed by a thorough overview of connectome studies on mental fatigue. Although only a limited number of studies have been published thus far, it is believed that the brain connectome can be a useful approach not only for the elucidation of underlying neural mechanisms in the nascent field of neuroergonomics, but also for the automatic detection and classification of mental fatigue in order to address the prevention of fatigue-related human error in the near future.展开更多
The objective was to study changes in EEG time-domain Kolmogorov complexity under different mental fatigue state and to evaluate mental fatigue using Lempel-Ziv complexity analysis of spontaneous EEG in healthy human ...The objective was to study changes in EEG time-domain Kolmogorov complexity under different mental fatigue state and to evaluate mental fatigue using Lempel-Ziv complexity analysis of spontaneous EEG in healthy human subjects. EEG data for healthy subjects were acquired using a net of 2 electrodes (Fp1 and Fp2) at PM 4:00, AM 12:00 and AM 3:00 in the 24 hours sleep-deprived mental fatigue experiments. It was presented that initial results for eight subjects examined in three different mental fa-tigue state with 2-channel EEG time-domain Lempel-Ziv complexity computations. It was found that the value of mean Lempel-Ziv com-plexity corresponding to a special mental state fluctuates within the special range and the value of C(n) increases with mental fatigue increasing for the total frequency spectrum. The result in-dicates that the value of C(n) is strongly cor-relative with the mental fatigue state. These re-sults suggest that it may be possible to nonin-vasively differentiate different mental fatigue level according to the value of C(n) for particular mental state from scalp spontaneous EEG data. This method may be useful in further research and efforts to evaluate mental fatigue level ob-jectively. It may also provide a basis for the study of effects of mental fatigue on central neural system.展开更多
Accurate assessment of mental fatigue level would improve operational safety and efficacy of astronauts for long-term space flight. Identification of neurophysiological markers can index impending overload or fatigue ...Accurate assessment of mental fatigue level would improve operational safety and efficacy of astronauts for long-term space flight. Identification of neurophysiological markers can index impending overload or fatigue before performance decrements using neuroimaging technologies. The current study utilized functional near-infrared spectroscopy (fNIR) to investigate the relationship of hemodynamic response in prefrontal cortex with changes of mental fatigue level, task performance (reaction time) during n-back working memory task and routine work task in analog space environment. Results indicated that the information entropy of hemodynamic response is related to task performance and subjective self-reported measures;the reaction time is predicted by regression analysis;and the accuracy of mental fatigue classification approaches 90%. Since fNIR is a portable, wearable and minimally intrusive methodology, it has the potential to be deployed in future space environments to monitoring mental fatigue and assessing the effort of operators in field environments.展开更多
Objective: The Microcompetition with Foreign DNA theory, proposed by Hanan Polansky in 2003, describes how latent viruses can cause chronic conditions, including fatigue. The Gene-Eden-VIR formula was designed to targ...Objective: The Microcompetition with Foreign DNA theory, proposed by Hanan Polansky in 2003, describes how latent viruses can cause chronic conditions, including fatigue. The Gene-Eden-VIR formula was designed to target latent viruses. Therefore, the theory predicts that treatment with Gene-Eden-VIR will decrease fatigue in individuals infected with a latent virus. The objective of this study was to test this prediction. Framework: A post marketing clinical study that followed FDA guidelines. Treatment: Gene-Eden-VIR, a dietary supplement. A capsule of Gene-Eden-VIR includes 100 mg of quercetin, 150 mg of green tea extract, 50 mg of cinnamon extract, 25 mg of licorice extract, and 100 mcg of selenium. The treatment included 1, 2, 3, or 4 capsules per day, and lasted 2 to 54 weeks. Population: 100 individuals infected with a latent virus, including the Human Papillomavirus (HPV), Epstein Barr Virus (EBV), Herpes Simplex Virus (HSV), Human Cytomegalovirus (HCMV), and Hepatitis C Virus (HCV). Ages ranged from 20 to 66. All participants reported a feeling of fatigue at the start of the study. Specifically, 98, 90, and 79 participants reported a feeling of general, physical, and mental fatigue, respectively. Results: Following treatment with Gene-Eden-VIR, 73.47%, 62.22%, and 47.36% reported a decrease in their feeling of general, physical, and mental fatigue, respectively. The participants also reported a statistically significant decrease in every aspect of fatigue tested in the study. The results also showed a duration effect, that is, those treated for 2 months or more reported a larger decrease in their feeling of fatigue (general, p = 0.03, n = 65;physical and mental, p = 0.05, n = 70). The results showed no interviewer bias, and no selection bias. In addition, the results showed therapeutic consistency under varying manufacturing conditions. The participants reported no side effects after taking Gene-Eden-VIR. Conclusions: This post marketing clinical study showed that treatment with Gene-Eden-VIR safely decreased the feeling of general, physical, and mental fatigue in individuals infected with a latent virus. Since most individuals are infected with a latent virus, health care practitioners should recommend Gene-Eden-VIR as a first line treatment for fatigue. The results of this post marketing clinical study support the Microcompetition with Foreign DNA theory.展开更多
Unhealthy mental states have become common among teachers recently. Subjective physical symptoms are more likely to appear more readily than mental symptoms. In this study, we revealed that the relationship between me...Unhealthy mental states have become common among teachers recently. Subjective physical symptoms are more likely to appear more readily than mental symptoms. In this study, we revealed that the relationship between mental states and subjective physical fatigue or pain in seven body sites among 2449 teachers. The 12-item General Health Questionnaire (GHQ-12) was used to assess mental state. We defined a score of 4 points and over in the GHQ-12 score as unhealthy mental state. We also asked about the presence of subjective physical fatigue or pain in each seven body sites in the past one year. In the results, 30.3% unhealthy mental states were found in females and 22.9% in males. Most of subjective physical fatigue or pains were detected in neck and shoulder, eyes, head and low back. Using multivariate logistic regression, higher scores in the GHQ-12 were positively associated with presence of subjective fatigue or pain in head and eyes in both genders, in lower extremities among females, and in back, upper extremities among males. Our results suggest that physical symptoms in specific body sites with gender differences may be useful in the early identification of unhealthy mental states among teachers. We should have efforts to pay attention to mental states among high school teachers if their symptoms do not get better after taking physical care.展开更多
Objective: This study aims to ascertain the prevalence of fatigue and depression from early postpartum to 1 month after delivery among postpartum women with mental disorders. Methods: The participants of this study we...Objective: This study aims to ascertain the prevalence of fatigue and depression from early postpartum to 1 month after delivery among postpartum women with mental disorders. Methods: The participants of this study were postpartum women who had delivered a child after a full-term pregnancy and were suffering from a mental disorder. We administered the Postpartum Fatigue Scale (PFS) on days 1, 3, and 4 (to multiparas), and 1, 3, and 5 (to primiparas), and 1 month after delivery to all participants. The Edinburgh Postnatal Depression Scale (EPDS), Japanese version, was also administered at the same time intervals as PFS except on day 3 after delivery. Results: A total of 7 primiparas and 9 multiparas participated in this study. The average age was 29.0 ± 7.0 years in primiparas and 32.0 ± 4.0 years in multiparas. The PFS scores were higher among the primiparas and peaked at day 1, and more than half the primiparas scored more than 9 points in EPDS. In addition, the EPDS score at 1 month had a strong correlation with the PFS subscale “mental stress situation” (r = 0.818/p = 0.047). In multiparas, the percentage of women who scored more than 9 points decreased. However, their EPDS scores at 1 month were related to the total scores of the PFS, “physical stress situation”, “mental stress situation”, and “sleep deprivation situation”. Especially, the score of “sleep deprivation situation” was higher than those during hospitalization. Conclusion: There was more fatigue 1 month after the discharge among postpartum women with mental disorders. The percentage of women whose EPDS scores were more than 9 points was high in both primiparas and multiparas. This study suggests assisting primiparas and multiparas by controlling the former’s disorder during childcare, and using family support for the latter, so that they get time to rest.展开更多
To investigate the effects of magnetic stimulation at acupoints on brain functional network during mental fatigue, magnetic stimulation was applied to stimulate SHENMEN (HT7), HEGU (LI4) and LAOGONG (PC8) acupoint in ...To investigate the effects of magnetic stimulation at acupoints on brain functional network during mental fatigue, magnetic stimulation was applied to stimulate SHENMEN (HT7), HEGU (LI4) and LAOGONG (PC8) acupoint in this paper. The brain functional networks of normal state, mental fatigue state and stimulated state were constructed and the characteristic parameters were comparatively studied based on the complex network theory. The results showed that the connection of the network was enhanced by stimulating the HT7, LI4 and PC8 acupoint. In conclusion, magnetic stimulation at acupoints can effectively relieve mental fatigue.展开更多
The aim of the study was to clarify the charac-teristics of fatigue status in Chinese adolescents. 1018 adolescents (490 males, 528 females) aged 12 or 15 years in Jixi city were enrolled. Between May and September 20...The aim of the study was to clarify the charac-teristics of fatigue status in Chinese adolescents. 1018 adolescents (490 males, 528 females) aged 12 or 15 years in Jixi city were enrolled. Between May and September 2009, fatigue status was investigated using a questionnaire devised by ourselves, which consisted of 4 physical and 4 mental fatigue items. These questions were scored from 0 to 3 based on the frequency of an item occurring, given as the average of the past one month, and the fatigue scores were calculated. Lifestyle issues such as daily sleep duration, feeling of refreshment in the morning after wake-up, extracurricular sports activity, and breakfast intake, and a physical examination such as height, weight, and waist circumference were also investigated. Physical and mental fatigue scores were significantly higher in subjects aged 15 yrs old than in those aged 12 yrs old in both genders. These scores in females were significantly higher than those in males at the age of 15 yrs. Multivariate regression analysis showed that total (physical plus mental) fatigue scores were associated with female gender and various lifestyles such as unrefreshed wake-up feeling, poor extracurricular sports activity, and more frequent skipping of breakfast. However, body mass index and waist circumference were not associated with total fatigue scores.展开更多
Application of continuous repetition of motor imagery can improve the performance of exercise tasks.However,there is a lack of more detailed neurophysiological evidence to support the formulation of clear standards fo...Application of continuous repetition of motor imagery can improve the performance of exercise tasks.However,there is a lack of more detailed neurophysiological evidence to support the formulation of clear standards for interventions using motor imagery.Moreover,identification of motor imagery intervention time is necessary because it exhibits possible central fatigue.Therefore,the purpose of this study was to elucidate the development of fatigue during continuous repetition of motor imagery through objective and subjective evaluation.The study involved two experiments.In experiment 1,14 healthy young volunteers were required to imagine grasping and lifting a 1.5-L plastic bottle using the whole hand.Each participant performed the motor imagery task 100 times under each condition with 48 hours interval between two conditions:500 mL or 1500 mL of water in the bottle during the demonstration phase.Mental fatigue and a decrease in pinch power appeared under the 1500-mL condition.There were changes in concentration ability or corticospinal excitability,as assessed by motor evoked potentials,between each set with continuous repetition of motor imagery also under the 1500-mL condition.Therefore,in experiment 2,12 healthy volunteers were required to perform the motor imagery task 200 times under the 1500-mL condition.Both concentration ability and corticospinal excitability decreased.This is the first study to show that continuous repetition of motor imagery can decrease corticospinal excitability in addition to producing mental fatigue.This study was approved by the Institutional Ethics Committee at the Nagasaki University Graduate School of Biomedical and Health Sciences(approval No.18121302)on January 30,2019.展开更多
文摘Mental fatigue is a complex state that results from prolonged cognitive activity. Symptoms of mental fatigue can include change in mood, motivation, and temporary deterioration of various cognitive functions involved in goal-directed behavior. Extensive research has been done to develop methods for recognizing physiological and psychophysiological signs of mental fatigue. This has allowed the development of many AI-based models to classify different levels of fatigue, using data extracted from eye-tracking device, EEG, or ECG. In this paper, we present an experimental protocol which aims to both generate/measure mental fatigue and provide effective strategies for recuperation via VR sessions paired with EEG and eye tracking devices. This paper first provides a comprehensive state-of-the-art of mental fatigue predictive factors, measurement methods, and recuperation strategies. Then the paper presents an experimental protocol resulting from the state-of-the-art to 1) generate and measure mental fatigue and 2) evaluate the effectiveness of virtual therapy for fatigue recuperation, using a virtual reality (VR) simulated environment. In our work, we successfully generated mental fatigue through completion of cognitive tasks in a virtual simulated environment. Participants showed significant decline in pupil diameter and theta/alpha score during the various cognitive tasks. We trained an RBF SVM classifier from Electroencephalogram (EEG) data classifying mental fatigue with 95% accuracy on the test set. Finally, our results show that the time allocated for virtual therapy did not improve pupil diameter in post-relaxation period. Further research on the impact of relaxation therapy on relaxation therapy should allocate time closer to the standard recovery time of 60 min.
文摘To explore the mechanisms underlying exercise-induced local muscle fatigue in patients with idiopathic Parkinson's disease (PD),we used surface electromyography to record myoelectric signals from the tibialis anterior muscle during isometric contraction-induced fatigue until exhaustion.The results revealed no significant differences between patients with idiopathic PD and healthy controls in maximum voluntary contraction of the tibialis anterior muscle.The basic characteristics of surface electromyography were also similar between the two groups.The duration of isometric contraction at 50% maximum voluntary contraction was shortened in PD patients.In addition,PD patients exhibited a stronger increase in mean square amplitude,but a weaker decrease in median frequency and mean power frequency compared with healthy controls during isometric contraction.The skeletal muscles of PD patients revealed specificity of surface electromyography findings,indicating increased fatigability compared with healthy controls.
基金the “Hundred Talents Program” of Zhejiang University (awarded to Yu Sun)the Fundamental Research Funds for the Central Universities (2018QNA5017, awarded to Yu Sun)the National Natural Science Foundation of China (81801785).
文摘Maintaining sustained attention during a prolonged cognitive task often comes at a cost: high levels of mental fatigue. Heuristically, mental fatigue refers to a feeling of tiredness or exhaustion, and a disengagement from the task at hand;it manifests as impaired cognitive and behavioral performance. In order to effectively reduce the undesirable yet preventable consequences of mental fatigue in many real-world workspaces, a better understanding of the underlying neural mechanisms is needed, and continuous efforts have been devoted to this topic. In comparison with conventional univariate approaches, which are widely utilized in fatigue studies, convergent evidence has shown that multivariate functional connectivity analysis may lead to richer information about mental fatigue. In fact, mental fatigue is increasingly thought to be related to the deviated reorganization of functional connectivity among brain regions in recent studies. In addition, graph theoretical analysis has shed new light on quantitatively assessing the reorganization of the brain functional networks that are modulated by mental fatigue. This review article begins with a brief introduction to neuroimaging studies on mental fatigue and the brain connectome, followed by a thorough overview of connectome studies on mental fatigue. Although only a limited number of studies have been published thus far, it is believed that the brain connectome can be a useful approach not only for the elucidation of underlying neural mechanisms in the nascent field of neuroergonomics, but also for the automatic detection and classification of mental fatigue in order to address the prevention of fatigue-related human error in the near future.
文摘The objective was to study changes in EEG time-domain Kolmogorov complexity under different mental fatigue state and to evaluate mental fatigue using Lempel-Ziv complexity analysis of spontaneous EEG in healthy human subjects. EEG data for healthy subjects were acquired using a net of 2 electrodes (Fp1 and Fp2) at PM 4:00, AM 12:00 and AM 3:00 in the 24 hours sleep-deprived mental fatigue experiments. It was presented that initial results for eight subjects examined in three different mental fa-tigue state with 2-channel EEG time-domain Lempel-Ziv complexity computations. It was found that the value of mean Lempel-Ziv com-plexity corresponding to a special mental state fluctuates within the special range and the value of C(n) increases with mental fatigue increasing for the total frequency spectrum. The result in-dicates that the value of C(n) is strongly cor-relative with the mental fatigue state. These re-sults suggest that it may be possible to nonin-vasively differentiate different mental fatigue level according to the value of C(n) for particular mental state from scalp spontaneous EEG data. This method may be useful in further research and efforts to evaluate mental fatigue level ob-jectively. It may also provide a basis for the study of effects of mental fatigue on central neural system.
文摘Accurate assessment of mental fatigue level would improve operational safety and efficacy of astronauts for long-term space flight. Identification of neurophysiological markers can index impending overload or fatigue before performance decrements using neuroimaging technologies. The current study utilized functional near-infrared spectroscopy (fNIR) to investigate the relationship of hemodynamic response in prefrontal cortex with changes of mental fatigue level, task performance (reaction time) during n-back working memory task and routine work task in analog space environment. Results indicated that the information entropy of hemodynamic response is related to task performance and subjective self-reported measures;the reaction time is predicted by regression analysis;and the accuracy of mental fatigue classification approaches 90%. Since fNIR is a portable, wearable and minimally intrusive methodology, it has the potential to be deployed in future space environments to monitoring mental fatigue and assessing the effort of operators in field environments.
文摘Objective: The Microcompetition with Foreign DNA theory, proposed by Hanan Polansky in 2003, describes how latent viruses can cause chronic conditions, including fatigue. The Gene-Eden-VIR formula was designed to target latent viruses. Therefore, the theory predicts that treatment with Gene-Eden-VIR will decrease fatigue in individuals infected with a latent virus. The objective of this study was to test this prediction. Framework: A post marketing clinical study that followed FDA guidelines. Treatment: Gene-Eden-VIR, a dietary supplement. A capsule of Gene-Eden-VIR includes 100 mg of quercetin, 150 mg of green tea extract, 50 mg of cinnamon extract, 25 mg of licorice extract, and 100 mcg of selenium. The treatment included 1, 2, 3, or 4 capsules per day, and lasted 2 to 54 weeks. Population: 100 individuals infected with a latent virus, including the Human Papillomavirus (HPV), Epstein Barr Virus (EBV), Herpes Simplex Virus (HSV), Human Cytomegalovirus (HCMV), and Hepatitis C Virus (HCV). Ages ranged from 20 to 66. All participants reported a feeling of fatigue at the start of the study. Specifically, 98, 90, and 79 participants reported a feeling of general, physical, and mental fatigue, respectively. Results: Following treatment with Gene-Eden-VIR, 73.47%, 62.22%, and 47.36% reported a decrease in their feeling of general, physical, and mental fatigue, respectively. The participants also reported a statistically significant decrease in every aspect of fatigue tested in the study. The results also showed a duration effect, that is, those treated for 2 months or more reported a larger decrease in their feeling of fatigue (general, p = 0.03, n = 65;physical and mental, p = 0.05, n = 70). The results showed no interviewer bias, and no selection bias. In addition, the results showed therapeutic consistency under varying manufacturing conditions. The participants reported no side effects after taking Gene-Eden-VIR. Conclusions: This post marketing clinical study showed that treatment with Gene-Eden-VIR safely decreased the feeling of general, physical, and mental fatigue in individuals infected with a latent virus. Since most individuals are infected with a latent virus, health care practitioners should recommend Gene-Eden-VIR as a first line treatment for fatigue. The results of this post marketing clinical study support the Microcompetition with Foreign DNA theory.
文摘Unhealthy mental states have become common among teachers recently. Subjective physical symptoms are more likely to appear more readily than mental symptoms. In this study, we revealed that the relationship between mental states and subjective physical fatigue or pain in seven body sites among 2449 teachers. The 12-item General Health Questionnaire (GHQ-12) was used to assess mental state. We defined a score of 4 points and over in the GHQ-12 score as unhealthy mental state. We also asked about the presence of subjective physical fatigue or pain in each seven body sites in the past one year. In the results, 30.3% unhealthy mental states were found in females and 22.9% in males. Most of subjective physical fatigue or pains were detected in neck and shoulder, eyes, head and low back. Using multivariate logistic regression, higher scores in the GHQ-12 were positively associated with presence of subjective fatigue or pain in head and eyes in both genders, in lower extremities among females, and in back, upper extremities among males. Our results suggest that physical symptoms in specific body sites with gender differences may be useful in the early identification of unhealthy mental states among teachers. We should have efforts to pay attention to mental states among high school teachers if their symptoms do not get better after taking physical care.
文摘Objective: This study aims to ascertain the prevalence of fatigue and depression from early postpartum to 1 month after delivery among postpartum women with mental disorders. Methods: The participants of this study were postpartum women who had delivered a child after a full-term pregnancy and were suffering from a mental disorder. We administered the Postpartum Fatigue Scale (PFS) on days 1, 3, and 4 (to multiparas), and 1, 3, and 5 (to primiparas), and 1 month after delivery to all participants. The Edinburgh Postnatal Depression Scale (EPDS), Japanese version, was also administered at the same time intervals as PFS except on day 3 after delivery. Results: A total of 7 primiparas and 9 multiparas participated in this study. The average age was 29.0 ± 7.0 years in primiparas and 32.0 ± 4.0 years in multiparas. The PFS scores were higher among the primiparas and peaked at day 1, and more than half the primiparas scored more than 9 points in EPDS. In addition, the EPDS score at 1 month had a strong correlation with the PFS subscale “mental stress situation” (r = 0.818/p = 0.047). In multiparas, the percentage of women who scored more than 9 points decreased. However, their EPDS scores at 1 month were related to the total scores of the PFS, “physical stress situation”, “mental stress situation”, and “sleep deprivation situation”. Especially, the score of “sleep deprivation situation” was higher than those during hospitalization. Conclusion: There was more fatigue 1 month after the discharge among postpartum women with mental disorders. The percentage of women whose EPDS scores were more than 9 points was high in both primiparas and multiparas. This study suggests assisting primiparas and multiparas by controlling the former’s disorder during childcare, and using family support for the latter, so that they get time to rest.
文摘To investigate the effects of magnetic stimulation at acupoints on brain functional network during mental fatigue, magnetic stimulation was applied to stimulate SHENMEN (HT7), HEGU (LI4) and LAOGONG (PC8) acupoint in this paper. The brain functional networks of normal state, mental fatigue state and stimulated state were constructed and the characteristic parameters were comparatively studied based on the complex network theory. The results showed that the connection of the network was enhanced by stimulating the HT7, LI4 and PC8 acupoint. In conclusion, magnetic stimulation at acupoints can effectively relieve mental fatigue.
文摘The aim of the study was to clarify the charac-teristics of fatigue status in Chinese adolescents. 1018 adolescents (490 males, 528 females) aged 12 or 15 years in Jixi city were enrolled. Between May and September 2009, fatigue status was investigated using a questionnaire devised by ourselves, which consisted of 4 physical and 4 mental fatigue items. These questions were scored from 0 to 3 based on the frequency of an item occurring, given as the average of the past one month, and the fatigue scores were calculated. Lifestyle issues such as daily sleep duration, feeling of refreshment in the morning after wake-up, extracurricular sports activity, and breakfast intake, and a physical examination such as height, weight, and waist circumference were also investigated. Physical and mental fatigue scores were significantly higher in subjects aged 15 yrs old than in those aged 12 yrs old in both genders. These scores in females were significantly higher than those in males at the age of 15 yrs. Multivariate regression analysis showed that total (physical plus mental) fatigue scores were associated with female gender and various lifestyles such as unrefreshed wake-up feeling, poor extracurricular sports activity, and more frequent skipping of breakfast. However, body mass index and waist circumference were not associated with total fatigue scores.
文摘Application of continuous repetition of motor imagery can improve the performance of exercise tasks.However,there is a lack of more detailed neurophysiological evidence to support the formulation of clear standards for interventions using motor imagery.Moreover,identification of motor imagery intervention time is necessary because it exhibits possible central fatigue.Therefore,the purpose of this study was to elucidate the development of fatigue during continuous repetition of motor imagery through objective and subjective evaluation.The study involved two experiments.In experiment 1,14 healthy young volunteers were required to imagine grasping and lifting a 1.5-L plastic bottle using the whole hand.Each participant performed the motor imagery task 100 times under each condition with 48 hours interval between two conditions:500 mL or 1500 mL of water in the bottle during the demonstration phase.Mental fatigue and a decrease in pinch power appeared under the 1500-mL condition.There were changes in concentration ability or corticospinal excitability,as assessed by motor evoked potentials,between each set with continuous repetition of motor imagery also under the 1500-mL condition.Therefore,in experiment 2,12 healthy volunteers were required to perform the motor imagery task 200 times under the 1500-mL condition.Both concentration ability and corticospinal excitability decreased.This is the first study to show that continuous repetition of motor imagery can decrease corticospinal excitability in addition to producing mental fatigue.This study was approved by the Institutional Ethics Committee at the Nagasaki University Graduate School of Biomedical and Health Sciences(approval No.18121302)on January 30,2019.