Properties of QCD matter:a review of selected results from ALICE experiment

The Large Hadron Collider(LHC), the world's largest and most powerful particle accelerator, has been a pivotal tool in advancing our understanding of fundamental physics. By colliding heavy ions, such as lead ions, the LHC recreates conditions similar to those just after the Big Bang. This allows scientists to study the quark-gluon plasma(QGP), a state of matter in which quarks and gluons are not confned within protons and neutrons. These studies provide valuable insights into the strong force and the behavior of the early universe. In this paper, we present a comprehensive overview of recent signifcant fndings from A Large Ion Collider Experiment(ALICE) at the LHC. The topics covered include measurements related to the properties of the QGP, particle production, fow and correlations, dileptons, quarkonia, and electromagnetic probes, heavy favor, and jets. Additionally, we introduce future plans for detector upgrades in the ALICE experiment.

Nomogram for overall survival in ampullary adenocarcinoma using the surveillance,epidemiology,and end results database and external validation

BACKGROUND Ampullary adenocarcinoma is a rare malignant tumor of the gastrointestinal tract.Currently,only a few cases have been reported,resulting in limited information on survival.AIM To develop a dynamic nomogram using internal and external validation to predict survival in patients with ampullary adenocarcinoma.METHODS Data were sourced from the surveillance,epidemiology,and end results stat database.The patients in the database were randomized in a 7:3 ratio into training and validation groups.Using Cox regression univariate and multivariate analyses in the training group,we identified independent risk factors for overall survival and cancer-specific survival to develop the nomogram.The nomogram was validated with a cohort of patients from the First Affiliated Hospital of the Army Medical University.RESULTS For overall and cancer-specific survival,12(sex,age,race,lymph node ratio,tumor size,chemotherapy,surgical modality,T stage,tumor differentiation,brain metastasis,lung metastasis,and extension)and 6(age;surveillance,epidemiology,and end results stage;lymph node ratio;chemotherapy;surgical modality;and tumor differentiation)independent risk factors,respectively,were incorporated into the nomogram.The area under the curve values at 1,3,and 5 years,respectively,were 0.807,0.842,and 0.826 for overall survival and 0.816,0.835,and 0.841 for cancer-specific survival.The internal and external validation cohorts indicated good consistency of the nomogram.CONCLUSION The dynamic nomogram offers robust predictive efficacy for the overall and cancer-specific survival of ampullary adenocarcinoma.

Generalization of Results of Computations and Natural Experiments at Steel Parts Quenching

Complicated changes occur inside the steel parts during quenching process. A three dimensional nonlinear mathematical model for quenching process has been established and the numerical simulation on temperature field, microstructure and stress field has been realized. The alternative technique for the formation of high-strength materials has been developed on the basis of intensification of heat transfer at phase transformations. The technology for the achievement of maximum compressive residual stresses on the hard surface is introduced. It has been shown that there is an optimal depth of hard layer providing the maximum compression stresses on the surface. It has also been established that in the surface hard layer additional strengthening (superstrengthening) of the material is observed. The generalized formula for the determination of the time of reaching maximum compressive stresses on the surface has been proposed.

Key Technology and Experimental Results of the Clean Air Heated Facility for Supersonic Combustion

The scramjet, which is the propulsion of hypersonic vehicle, has become the focus in many military developed countries. The ground tests play an important role in the research of scramjet. There is defect of test medium contamination （the thermochemical characteristic of the ground test medium is different from that of the flight medium） in existing ground test facilities for scramjet combustor experiment. To solve the problem of test medium contamination, the first clean air heated facility of China for scramjet combustor experiment is designed. The key technology of designing the clean air heated facility is summarized. By using bypass duct, combustor model is protected from high temperature. To reduce the switching time between main duct and bypass duct, solenoid valve and water-cooled system were used. Having centrosymmetric structure, the heat radiating area of the facility and heat loss of the facility are much lower than others. Clean air heated facility is adopted to conduct experiment, which is the first experiment of China in clean air inflow, research on hydrogen-fueled and ethylene-fueled ignition and combustion for scramjet combustor at different equivalence ratio. Successful ignition and sustained combustion of hydrogen has been achieved. Successful ethylene ignition and sustained main stream combustion is achieved with normal fuel injection and taking hydrogen as pilot flame. Experiment result shows that the wall pressure of combustor model rises when the equivalence ratio of hydrogen rises. As the wall pressure of combustor model rises, the pressure disturbance influences the shock train in the upstream.

Preliminary Results from Numerical Experiments of a Heavy Rain Process with PENN STATE / NCAR MM5

PENN STATE/NCAR MM5 is used to simulate precipitation of the heavy rain process during 12-13 July 1994.The effects of different PBL parameterizations,resolvable scale moisture schemes and cumulus parameterization on the process rainfall simulation are investigated.By comparing the results of hydrostatic and nor.hydrostatic experiments,the nonhydrostatic impact upon precipitation is also examined.It is found in this study thai PENN STATE/NCAR MM5 has advantage not only in theory but also in simulating results with real data.In MM5.however,the selection of physical processes,especially water-cycle process,is very important and crucial to precipitation forecast of the case.It is concluded that the model with Grell (1993) scheme for convection and condensation method for resolvable scale precipitation captured the rainstorm during 12-13 July 1994 in Beijing area more successfully

Preliminary Results of the Ground-Based Orographic Snow Enhancement Experiment for the Easterly Cold Fog (Cloud) at Daegwallyeong during the 2006 Winter

The snow enhancement experiments, carried out by injecting AgI and water vapor into orographically enhanced clouds （fog）, have been conducted to confirm Li and Pitter＇s forced condensation process in a natural situation. Nine ground-based experiments have been conducted at Daegwallyeong in the Taebaek Mountains for the easterly foggy days from January-February 2006. We then obtained the optimized conditions for the Daegwallyeong region as follows： the small seeding rate （1.04 g min-1） of AgI for the easterly cold fog with the high humidity of Gangneung. Additional experiments are needed to statistically estimate the snowfall increment caused by the small AgI seeding into the orographical fog （cloud） over the Taeback Mountains.

The Experimental Results of Pb and Zn Partitioning between Fluid and Melt, and Their Application to the Research on Metallogeny

Three logarithmic linear equations between D_(Me)^(V/L) and [m_(NaCl)], and the relationship of D_(Me)^(V/L) versus F/Cl or K/Na mole ratios have been established by the experiments of the partitioning of Pb and Zn between granitic silicate melt and aqueous fluid. These results have been used to quantitatively study some essential problems, such as the possibility and degree of Pb-Zn mineralization in the system of granitic magma and hydrothermal fluid, and the influence of the relative contents of alkali and volatiles on the Pb-Zn mineralization in the same system. Some new points have been put forward in this paper.

Overview of HL-2A Experiment Results

The recent experiment results of the HL-2A tokamak are presented in this paper. Up to now, the stable and reproducible discharges with divertor configuration have been obtained under the main plasma parameters of Ip=433 kA, BT=2.70 T, ne-6.0×10^19 m^-3 and the discharge duration -3.0 s, using the reliable feedback control. Siliconization is the normal wall conditioning method on HL-2A. The impurity concentration and radiated power can be obviously suppressed after siliconization. Advanced scenario with weak positive/negative current shear, calculated by TRANSP codes using experimental data, is achieved by the central fuelling of the pellet injection. The supersonic molecular beam injection （SMBI） with liquid nitrogen temperature gas is used. It is proved that the low temperature SMBI can form the hydrogen cluster and penetrate into plasma more deeply and efficiently. The particle diffusion coefficient is obtained as 0.5 - 1.5 m^2/s at plasma peripheral area. The symmetries （m = 0- 1, n = 0） of the directly measured low frequency （7 -9 kHz ） electric potential and field are simultaneously observed for the first time by a novel designed Langmuir probe system. The impurity diffusion coefficient and convection velocity are determined by using laser blow-off system and transport code. In disruption studies, a new criterion for disruption prediction is given according to the MHD activity features and statistic analysis, and the plasma current quench time increases from about 5 ms to 20 ms with noble gas injection. The sawtooth character in on-axis ECRH experiment is investigated, and a persistent m= 1 oscillation induced by SMBI and pellet injection is found to be a thermal fluctuation instead of magnetic island. The detachment characteristics of HL-2A divertor are numerically and experimentally studied using code SOLPS5.0 and measured data. The long divertor legs and thin divertor throats in HL-2A pose MHD shaping problems resulting in momentum losses even at low densities and strongly enhanced main chamber losses.

Some results of modeling D-D seismogenic pattern by the fracture model experiment of large-scale rock samples(I)

sing the natural limestone samples taken from the field with dimension of 500 mm×500 mm×1 000 mm, the D-D (dilatancy-diffusion) seismogeny pattern was modeled under the condition of water injection, which observes the time-space evolutionary features about the relative physics fields of the loaded samples from deformation, formation of microcracks to the occurrence of main rupture. The results of observed apparent resistivity show: ① The process of the deformation from microcrack to main rupture on the loaded rock sample could be characterized by the precursory spatial-temporal changes in the observation of apparent resistivity; ② The precursory temporal changes of observation in apparent resistivity could be divided into several stages, and its spatial distribution shows the difference in different parts of the rock sample; ③ Before the main rupture of the rock sample the obvious ″tendency anomaly′ and ′short-term anomaly″ were observed, and some of them could be likely considered as the ″impending earthquake ″anomaly precursor of apparent resistivity. The changes and distribution features of apparent resistivity show that they are intrinsically related to the dilatancy phenomenon of the loaded rock sample. Finally, this paper discusses the mechanism of resistivity change of loaded rock sample theoretically.

A METHOD OF ESTIMATING THE INFLUENCE OF EXPERIMENTAL ERRORS ON THE EXPERIMENTAL RESULTS OF MATERIAL PARAMETERS AND THE CRITERIA TO VALUE THIS INFLUENCE

In this paper the main sources causing the scatter of the experimental results of the material parameters are discussed. They can be divided into two parts: one is the experimental errors which are introduced because of the inaccuracy of experimental equipment, the experimental techniques, etc., and the form of the scatter caused by this source is called external distribution. The other is due to the irregularity and inhomogeneity of the material structure and the randomness of deformation process. The scatter caused by this source is inherent and then this form of the scatter is called internal distribution. Obviously the experimental distribution of material parameters combines these two distributions in some way; therefore, it is a sum distribution of the external distribution and the internal distribution. In view of this , a general method used to analyse the influence of the experimental errors on the experimental results is presented, and three criteria used to value this influence are defined. An example in which the fracture toughness KIC is analysed shows that this method is reasonable, convenient and effective.

Computational Experiments for Complex Social Systems:Experiment Design and Generative Explanation

Powered by advanced information technology,more and more complex systems are exhibiting characteristics of the cyber-physical-social systems(CPSS).In this context,computational experiments method has emerged as a novel approach for the design,analysis,management,control,and integration of CPSS,which can realize the causal analysis of complex systems by means of“algorithmization”of“counterfactuals”.However,because CPSS involve human and social factors(e.g.,autonomy,initiative,and sociality),it is difficult for traditional design of experiment(DOE)methods to achieve the generative explanation of system emergence.To address this challenge,this paper proposes an integrated approach to the design of computational experiments,incorporating three key modules:1)Descriptive module:Determining the influencing factors and response variables of the system by means of the modeling of an artificial society;2)Interpretative module:Selecting factorial experimental design solution to identify the relationship between influencing factors and macro phenomena;3)Predictive module:Building a meta-model that is equivalent to artificial society to explore its operating laws.Finally,a case study of crowd-sourcing platforms is presented to illustrate the application process and effectiveness of the proposed approach,which can reveal the social impact of algorithmic behavior on“rider race”.

Observational results of electromagnetic radiation caused by explosion of small dimension rocks in field experiments

In order to probe the mechanism of the phenomena of seismic electromagnetic radiation (EMR), we have completed field experiment on EMR caused by explosiom of rocks. In the experiments, the data of medium low freguency (<5000 Hz) EMR caused by 26 explosion tests of small dimension rocks have been obtained. This paper shows some representative observational results of the field experiment. The observational results show that, nearly 20 points of the 26 explosive points, the EMR phenomena are recorded at various degrees in the related explosive processes. The EMR intensities decay with the distance from explosive origins and increase with the explosive energy. The EMR records have certain repeatability (under the same condition), complexity( multiple EMR effects caused by one explosion) and regional characteristics such as rock structure and observational direction etc.

Calculating buoy response for a wave energy converter-A comparison of two computational methods and experimental results

When designing a wave power plant, reliable and fast simulation tools are required. Computational fluid dynamics （CFD） software provides high accuracy but with a very high computational cost, and in operational, moderate sea states, linear potential flow theories may be sufficient to model the hydrodynamics. In this paper, a model is built in COMSOL Multiphysics to solve for the hydrodynamic parameters of a point-absorbing wave energy device. The results are compared with a linear model where the hydrodynamical parameters are computed using WAMIT, and to experimental results from the Lysekil research site. The agreement with experimental data is good for both numerical models.

Effects of Selective Contracting with Positive Incentives on the Choices of Dutch Consumers for Health Care Options: Results of an Experiment

Since the introduction of the Health Insurance Act in the Netherlands in 2006, insurers are incen-tivized to compete on price for basic health insurance, and on price and quality for supplementary insurance. It is possible for health insurers to implement a differentiated deductible since the first of January 2009. This paper describes an experiment. It is designed to study this differentiated deductible as a financial policy instrument. It focuses on the effect of selective contracting with positive incentives on the choice-behaviour of the insured. The goal of this study is to gain insight in the working mechanism of this financial policy instrument that is meant to reduce healthcare costs. The study is designed as a vignette study. The vignettes are presented in pairs of two to the respondents. The vignettes contain various elements including premium costs, deductible, degree of selective contracting and availability of quality-information (CQI). As the respondents in the design of this choice experiment have to choose between confronting health plans, it is understandable that they value these policies on their characteristics (so-called attributes). Subsequently, a statement can be formulated on the relative value assigned to these attributes by the respondents, clearly preferring one health plan over the other. Finally 99 respondents were included in our study. Logistic regression analysis was performed. This study shows that the deducti-ble as choice-influencing instrument has less influence as age increases. The proclaimed cost savings of this deductible might be lower than expected. Generally, it can be concluded that healthier people are less likely to choose the extensive health plan. However, this effect reverses when the most extensive and less extensive are presented to the participants. The results thus show a clear demarcation in the preferences of consumers. A similar demarcation also has been found in the data concerning travel distance. When contracted care is within 30 minutes, this health plan is preferred over the more extensive and expensive one. However, this study also shows that this effect reverses when the travel distance increases to 45 minutes. Consumers in this situation are reluctant to choose selective care and choose for the extensive and expensive option. Premium costs have a negative effect. A health plan becomes less attractive when the price increases. In addition, an increase in the availability of CQI makes a health plan more attractive. It can be concluded from this study that the deductible as choice-influencing instrument seems to work for young and healthy people, provided that they do not have to travel more that 30 minutes.

Noise color influence on escape times in nonlinear oscillators-experimental and numerical results

The interplay between noise and nonlinearites can lead to escape dynamics.Associated nonlinear phe-nomena have been observed in various applications ranging from climatology to biology and engineering.For reasons of computational ease,in most studies,Gaussian white noise is used.However,this noise model is not physical due to the associated infinite energy content.Here,the authors present extensive experimental investigations and numerical simulations conducted to examine the impact of noise color on escape times in nonlinear oscillators.With a careful parameterization of the numerical simulations,the authors are able to make quantitative comparisons with experimental results.Through the experi-ments and simulations,it is illustrated that the noise color can drastically influence escape times and escape probability.

Predicting the probability distribution of Martian rocks mechanical property based on microscale rock mechanical experiments and accurate grain-based modeling

The exploration of Mars would heavily rely on Martian rocks mechanics and engineering technology.As the mechanical property of Martian rocks is uncertain,it is of utmost importance to predict the probability distribution of Martian rocks mechanical property for the success of Mars exploration.In this paper,a fast and accurate probability distribution method for predicting the macroscale elastic modulus of Martian rocks was proposed by integrating the microscale rock mechanical experiments(micro-RME),accurate grain-based modeling(AGBM)and upscaling methods based on reliability principles.Firstly,the microstructure of NWA12564 Martian sample and elastic modulus of each mineral were obtained by micro-RME with TESCAN integrated mineral analyzer(TIMA)and nanoindentation.The best probability distribution function of the minerals was determined by Kolmogorov-Smirnov(K-S)test.Secondly,based on best distribution function of each mineral,the Monte Carlo simulations(MCS)and upscaling methods were implemented to obtain the probability distribution of upscaled elastic modulus.Thirdly,the correlation between the upscaled elastic modulus and macroscale elastic modulus obtained by AGBM was established.The accurate probability distribution of the macroscale elastic modulus was obtained by this correlation relationship.The proposed method can predict the probability distribution of Martian rocks mechanical property with any size and shape samples.

Network pharmacology study and in vitro experimental validation of Xiaojianzhong decoction against gastric cancer

BACKGROUND Cancer is one of the most serious threats to human health worldwide.Conventional treatments such as surgery and chemotherapy are associated with some drawbacks.In recent years,traditional Chinese medicine treatment has been increasingly advocated by patients and attracted attention from clinicians,and has become an indispensable part of the comprehensive treatment for gastric cancer.AIM To investigate the mechanism of Xiaojianzhong decoction(XJZ)in the treatment of gastric cancer(GC)by utilizing network pharmacology and experimental validation,so as to provide a theoretical basis for later experimental research.METHODS We analyzed the mechanism and targets of XJZ in the treatment of GC through network pharmacology and bioinformatics.Subsequently,we verified the impact of XJZ treatment on the proliferative ability of GC cells through CCK-8,apoptosis,cell cycle,and clone formation assays.Additionally,we performed Western blot analysis and real-time quantitative PCR to assess the protein and mRNA expression of the core proteins.RESULTS XJZ mainly regulates IL6,PTGS2,CCL2,MMP9,MMP2,HMOX1,and other target genes and pathways in cancer to treat GC.The inhibition of cell viability,the increase of apoptosis,the blockage of the cell cycle at the G0/G1 phase,and the inhibition of the ability of cell clone formation were observed in AGS and HGC-27 cells after XJZ treatment.In addition,XJZ induced a decrease in the mRNA expression of IL6,PTGS2,MMP9,MMP2,and CCL2,and an increase in the mRNA expression of HOMX1.XJZ significantly inhibited the expression of IL6,PTGS2,MMP9,MMP2,and CCL2 proteins and promoted the expression of the heme oxygenase-1 protein.CONCLUSION XJZ exerts therapeutic effects against GC through multiple components,multiple targets,and multiple pathways.Our findings provide a new idea and scientific basis for further research on the molecular mechanisms underlying the therapeutic effects of XJZ in the treatment of GC.

Experimental and simulation research on hollow AZ31 magnesium alloy three-channel joint by hot extrusion forming with sand mandrel

Magnesium alloy is one of the lightest metal structural materials.The weight is further reduced through the hollow structure.However,the hollow structure is easily damaged during processing.In order to maintain the hollow structure and to transfer the stresses during the high temperature deformation,the sand mandrel is proposed.In this paper,the hollow AZ31 magnesium alloy three-channel joint is studied by hot extrusion forming.Sand as one of solid granule medium is used to fill the hollow magnesium alloy.The extrusion temperatures are 230℃ and 300℃,respectively.The process parameters(die angle,temperature,bottom thickness,sidewall thickness,edge-to-middle ratio in bottom,bottom shape)of the hollow magnesium alloy are analyzed based on the results of experiments and the finite element method.The results are shown that the formability of the hollow magnesium alloy will be much better when the ratio of sidewall thickness to the bottom thickness is 1:1.5.Also when edge-to-middle ratio in bottom is about 1:1.5,a better forming product can be received.The best bottom shape in these experiments will be convex based on the forming results.The grain will be refined obviously after the extrusion.Also the microstructures will be shown as streamlines.And these lines will be well agreement with the mold in the corner.

Nepheloid layer generation by gas eruption:unexpected experimental results

Knowledge of nepheloid layers is important to improve the understanding of physical,geological,and sedimentary processes from continental shelf to abyssal environments.We had not tried to study the nepheloid layers in a hydrate-associated tank until unexpected results occurred.Tank experimental results show that gas eruptions triggered intermediate nepheloid layers.Thus,we proposed a new mechanism of intermediate nepheloid layer generation by eruptions.The intermediate nepheloid layers were generated in uniform-density fluid,which indicated that stratified fluid is not a necessary condition for intermediate nepheloid layers.Sufficient space for advection and an oblique slope for detachment are the key ingredients for intermediate nepheloid layer generation by eruptions.Our experiments also offer a new experimental evidence for bottom nepheloid layer generation by earthquakes.Given the scale effects of laboratory experiment,it is important to determine whether submarine volcanic eruption or hydrate-associated venting causes intermediate nepheloid layer in the nature.

Design and analysis of an advanced thermal management system for the solar close observations and proximity experiments spacecraft

In this paper,the mission and the thermal environment of the Solar Close Observations and Proximity Experiments(SCOPE)spacecraft are analyzed,and an advanced thermal management system(ATMS)is designed for it.The relationship and functions of the integrated database,the intelligent thermal control system and the efficient liquid cooling system in the ATMS are elaborated upon.For the complex thermal field regulation system and extreme space thermal environment,a modular simulation and thermal field planning method are proposed,and the feasibility of the planning algorithm is verified by numerical simulation.A solar array liquid cooling system is developed,and the system simulation results indicate that the temperatures of the solar arrays meet the requirements as the spacecraft flies by perihelion and aphelion.The advanced thermal management study supports the development of the SCOPE program and provides a reference for the thermal management in other deep-space exploration programs.