We investigated the protective effects of electromagnetic field（EMF）on the survival of the human renal proximal tubular cell line,HK-2,using an in vitro hypoxia/reoxygenation（H/R）injury model.The survival rate of ...We investigated the protective effects of electromagnetic field（EMF）on the survival of the human renal proximal tubular cell line,HK-2,using an in vitro hypoxia/reoxygenation（H/R）injury model.The survival rate of cells cultured under H/R condition declined significantly,while the intracellular reactive oxygen species（ROS）levels markedly increased.The 10 Hz/1 m T EMF exposure could inhibit H/R-induced cell death of HK-Z via suppression of intracellular ROS production and that this treatment might be clinically useful for the amelioration of renal ischemia/reperfusion injury.展开更多
基金supported by the Pioneer Research Center Program through the National Research Foundation of Korea funded by the Ministry of Education,Science and Technology(NRF-2009-0082941)
文摘We investigated the protective effects of electromagnetic field（EMF）on the survival of the human renal proximal tubular cell line,HK-2,using an in vitro hypoxia/reoxygenation（H/R）injury model.The survival rate of cells cultured under H/R condition declined significantly,while the intracellular reactive oxygen species（ROS）levels markedly increased.The 10 Hz/1 m T EMF exposure could inhibit H/R-induced cell death of HK-Z via suppression of intracellular ROS production and that this treatment might be clinically useful for the amelioration of renal ischemia/reperfusion injury.
