Rebuilding the damaged motor function caused by spinal cord injury is one of the most serious challenges in clinical neuroscience.The function of the neural pathway under the damaged sites can be rebuilt using functio...Rebuilding the damaged motor function caused by spinal cord injury is one of the most serious challenges in clinical neuroscience.The function of the neural pathway under the damaged sites can be rebuilt using functional electrical stimulation technology.In this study,the locations of motor function sites in the lumbosacral spinal cord were determined with functional electrical stimulation technology.A three-dimensional map of the lumbosacral spinal cord comprising the relationship between the motor function sites and the corresponding muscle was drawn.Based on the individual experimental parameters and normalized coordinates of the motor function sites,the motor function sites that control a certain muscle were calculated.Phasing pulse sequences were delivered to the determined motor function sites in the spinal cord and hip extension,hip flexion,ankle plantarflexion,and ankle dorsiflexion movements were successfully achieved.The results show that the map of the spinal cord motor function sites was valid.This map can provide guidance for the selection of electrical stimulation sites during the rebuilding of motor function after spinal cord injury.展开更多
Based on new multibeam bathymetric data and about 300 km long single seismic profiles, three topographic units were identified: the canyons, fractural valley and submarine terrace on the north of Chiwei Island where ...Based on new multibeam bathymetric data and about 300 km long single seismic profiles, three topographic units were identified: the canyons, fractural valley and submarine terrace on the north of Chiwei Island where is a structural transition zone between the southern trough and the middle trough. The Chiwei Canyon and the North Chiwei Canyon are two of the largest canyons in the East China Sea (ECS) slope. Topographic features and architectures of them are described. The study shows that both of them are originated along faults. The evolution and spatial distribution of topographic units in the study area are controlled mainly by three groups of faults which were formed and reactive in the recent extensional phase of Okinawa Trough. The Chiwei Canyon was initia- ted during the middle Pleistocene and guided by F4 that is a N--S trending fault on the slope and F1, a large NW--SE trending fault on the trough. The pathway migration from the remnant channel to the present one of Chiwei Canyon is the result of uplift of tilted fault block that is coupled to the recent extension movements of the southern trough. The submarine terrace is detached from the ECS slope by the NEE -trending fault. The North Chiwei Canyon, developing during the late Pleistocene, is guided by FS, a N-S trending fault, diverted and blocked by the submarine terrace.展开更多
基金supported by the National Natural Science Foundation of China,No.81371663,61534003the Top-notch Academic Programs Project of Jiangsu Higher Education Institutions of China,No.PPZY2015B135
文摘Rebuilding the damaged motor function caused by spinal cord injury is one of the most serious challenges in clinical neuroscience.The function of the neural pathway under the damaged sites can be rebuilt using functional electrical stimulation technology.In this study,the locations of motor function sites in the lumbosacral spinal cord were determined with functional electrical stimulation technology.A three-dimensional map of the lumbosacral spinal cord comprising the relationship between the motor function sites and the corresponding muscle was drawn.Based on the individual experimental parameters and normalized coordinates of the motor function sites,the motor function sites that control a certain muscle were calculated.Phasing pulse sequences were delivered to the determined motor function sites in the spinal cord and hip extension,hip flexion,ankle plantarflexion,and ankle dorsiflexion movements were successfully achieved.The results show that the map of the spinal cord motor function sites was valid.This map can provide guidance for the selection of electrical stimulation sites during the rebuilding of motor function after spinal cord injury.
基金The National Natural Science Foundation of China under contract Nos 40576033 and 40406013
文摘Based on new multibeam bathymetric data and about 300 km long single seismic profiles, three topographic units were identified: the canyons, fractural valley and submarine terrace on the north of Chiwei Island where is a structural transition zone between the southern trough and the middle trough. The Chiwei Canyon and the North Chiwei Canyon are two of the largest canyons in the East China Sea (ECS) slope. Topographic features and architectures of them are described. The study shows that both of them are originated along faults. The evolution and spatial distribution of topographic units in the study area are controlled mainly by three groups of faults which were formed and reactive in the recent extensional phase of Okinawa Trough. The Chiwei Canyon was initia- ted during the middle Pleistocene and guided by F4 that is a N--S trending fault on the slope and F1, a large NW--SE trending fault on the trough. The pathway migration from the remnant channel to the present one of Chiwei Canyon is the result of uplift of tilted fault block that is coupled to the recent extension movements of the southern trough. The submarine terrace is detached from the ECS slope by the NEE -trending fault. The North Chiwei Canyon, developing during the late Pleistocene, is guided by FS, a N-S trending fault, diverted and blocked by the submarine terrace.