This paper studies a strongly convergent inertial forward-backward-forward algorithm for the variational inequality problem in Hilbert spaces.In our convergence analysis,we do not assume the on-line rule of the inerti...This paper studies a strongly convergent inertial forward-backward-forward algorithm for the variational inequality problem in Hilbert spaces.In our convergence analysis,we do not assume the on-line rule of the inertial parameters and the iterates,which have been assumed by several authors whenever a strongly convergent algorithm with an inertial extrapolation step is proposed for a variational inequality problem.Consequently,our proof arguments are different from what is obtainable in the relevant literature.Finally,we give numerical tests to confirm the theoretical analysis and show that our proposed algorithm is superior to related ones in the literature.展开更多
We use the extrapolated Tikhonov regularization to deal with the ill-posed problem of 3D density inversion of gravity gradient data. The use of regularization parameters in the proposed method reduces the deviations b...We use the extrapolated Tikhonov regularization to deal with the ill-posed problem of 3D density inversion of gravity gradient data. The use of regularization parameters in the proposed method reduces the deviations between calculated and observed data. We also use the depth weighting function based on the eigenvector of gravity gradient tensor to eliminate undesired effects owing to the fast attenuation of the position function. Model data suggest that the extrapolated Tikhonov regularization in conjunction with the depth weighting function can effectively recover the 3D distribution of density anomalies. We conduct density inversion of gravity gradient data from the Australia Kauring test site and compare the inversion results with the published research results. The proposed inversion method can be used to obtain the 3D density distribution of underground anomalies.展开更多
Tikhonov regularization(TR) method has played a very important role in the gravity data and magnetic data process. In this paper, the Tikhonov regularization method with respect to the inversion of gravity data is d...Tikhonov regularization(TR) method has played a very important role in the gravity data and magnetic data process. In this paper, the Tikhonov regularization method with respect to the inversion of gravity data is discussed. and the extrapolated TR method(EXTR) is introduced to improve the fitting error. Furthermore, the effect of the parameters in the EXTR method on the fitting error, number of iterations, and inversion results are discussed in details. The computation results using a synthetic model with the same and different densities indicated that. compared with the TR method, the EXTR method not only achieves the a priori fitting error level set by the interpreter but also increases the fitting precision, although it increases the computation time and number of iterations. And the EXTR inversion results are more compact than the TR inversion results, which are more divergent. The range of the inversion data is closer to the default range of the model parameters, and the model features and default model density distribution agree well.展开更多
Autoregressive (AR) modeling is applied to data extrapolation of radio frequency (RF) echo signals, and Burg algorithm, which can be computed in small amount and lead to a stable prediction filter, is used to estimate...Autoregressive (AR) modeling is applied to data extrapolation of radio frequency (RF) echo signals, and Burg algorithm, which can be computed in small amount and lead to a stable prediction filter, is used to estimate the prediction parameters of AR modeling. The complex data samples are directly extrapolated to obtain the extrapolated echo data in the frequency domain. The small rotating angle data extrapolation and the large rotating angular data extrapolation are considered separately in azimuth domain. The method of data extrapolation for the small rotating angle is the same as that in frequency domain, while the amplitude samples of large rotating angle echo data are extrapolated to obtain extrapolated echo amplitude, and the complex data of large rotating angle echo samples are extrapolated to get the extrapolated echo phase respectively. The calculation results show that the extrapolated echo data obtained by the above mentioned methods are accurate.展开更多
This paper deals with the recommendation system in the so-called user-centric payment environment where users,i.e.,the payers,can make payments without providing self-information to merchants.This service maintains on...This paper deals with the recommendation system in the so-called user-centric payment environment where users,i.e.,the payers,can make payments without providing self-information to merchants.This service maintains only the minimum purchase information such as the purchased product names,the time of purchase,the place of purchase for possible refunds or cancellations of purchases.This study aims to develop AI-based recommendation system by utilizing the minimum transaction data generated by the user-centric payment service.First,we developed a matrix-based extrapolative collaborative filtering algorithm based on open transaction data.The recommendation methodology was verified with the real transaction data.Based on the experimental results,we confirmed that the recommendation performance is satisfactory only with the minimum purchase information.展开更多
A series of SnO2‐based catalysts modified by Mn, Zr, Ti and Pb oxides with a Sn/M (M=Mn, Zr, Ti and Pb) molar ratio of 9/1 were prepared by a co‐precipitation method and used for CH4 and CO oxidation. The Mn3+, ...A series of SnO2‐based catalysts modified by Mn, Zr, Ti and Pb oxides with a Sn/M (M=Mn, Zr, Ti and Pb) molar ratio of 9/1 were prepared by a co‐precipitation method and used for CH4 and CO oxidation. The Mn3+, Zr4+, Ti4+and Pb4+cations are incorporated into the lattice of tetragonal rutile SnO2 to form a solid solution structure. As a consequence, the surface area and thermal stability of the catalysts are improved. Moreover, the oxygen species of the modified catalysts become easier to be reduced. Therefore, the oxidation activity over the catalysts was improved, except for the one modified by Pb oxide. Manganese oxide demonstrates the best promotional effects for SnO2. Using an X‐ray diffraction extrapolation method, the lattice capacity of SnO2 for Mn2O3 was 0.135 g Mn2O3/g SnO2, which indicates that to form stable solid solution, only 21%Sn4+cations in the lattice can be maximally replaced by Mn3+. If the amount of Mn3+cations is over the capacity, Mn2O3 will be formed, which is not favorable for the activity of the catalysts. The Sn rich samples with only Sn‐Mn solid solution phase show higher activity than the ones with excess Mn2O3 species.展开更多
Extending the lead time of precipitation nowcasts is vital to improvements in heavy rainfall warning, flood mitigation, and water resource management. Because the TREC vector (tracking radar echo by correlation) rep...Extending the lead time of precipitation nowcasts is vital to improvements in heavy rainfall warning, flood mitigation, and water resource management. Because the TREC vector (tracking radar echo by correlation) represents only the instantaneous trend of precipitation echo motion, the approach using derived echo motion vectors to extrapolate radar reflectivity as a rainfall forecast is not satisfactory if the lead time is beyond 30 minutes. For longer lead times, the effect of ambient winds on echo movement should be considered. In this paper, an extrapolation algorithm that extends forecast lead times up to 3 hours was developed to blend TREC vectors with model-predicted winds. The TREC vectors were derived from radar reflectivity patterns in 3 km height CAPPI (constant altitude plan position indicator) mosaics through a cross-correlation technique. The background steering winds were provided by predictions of the rapid update assimilation model CHAF (cycle of hourly assimilation and forecast). A similarity index was designed to determine the vertical level at which model winds were applied in the extrapolation process, which occurs via a comparison between model winds and radar vectors. Based on a summer rainfall case study, it is found that the new algorithm provides a better forecast.展开更多
A new radar echo tracking algorithm known as multi-scale tracking radar echoes by cross-correlation (MTREC) was developed in this study to analyze movements of radar echoes at different spatial scales. Movement of r...A new radar echo tracking algorithm known as multi-scale tracking radar echoes by cross-correlation (MTREC) was developed in this study to analyze movements of radar echoes at different spatial scales. Movement of radar echoes, particularly associated with convective storms, exhibits different characteristics at various spatial scales as a result of complex interactions among meteorological systems leading to the formation of convective storms. For the null echo region, the usual correlation technique produces zero or a very small magnitude of motion vectors. To mitigate these constraints, MTREC uses the tracking radar echoes by correlation (TREC) technique with a large "box" to determine the systematic movement driven by steering wind, and MTREC applies the TREC technique with a small "box" to estimate small-scale internal motion vectors. Eventually, the MTREC vectors are obtained by synthesizing the systematic motion and the small-scale internal motion. Performance of the MTREC technique was compared with TREC technique using case studies: the Khanun typhoon on 11 September 2005 observed by Wenzhou radar and a squall-line system on 23 June 2011 detected by Beijing radar. The results demonstrate that more spatially smoothed and continuous vector fields can be generated by the MTREC technique, which leads to improvements in tracking the entire radar reflectivity pattern. The new multi-scMe tracking scheme was applied to study its impact on the performance of quantitative precipitation nowcasting. The location and intensity of heavy precipitation at a 1-h lead time was more consistent with quantitative precipitation estimates using radar and rain gauges.展开更多
In this paper we employ the Petrov Galerkin method for the parabolic problems to get the finite element approximate solution of high accuracy by means of the interpolation postprocessing, extrapolation and defect cor...In this paper we employ the Petrov Galerkin method for the parabolic problems to get the finite element approximate solution of high accuracy by means of the interpolation postprocessing, extrapolation and defect correction techniques.展开更多
By coupling the non-equilibrium extrapolation scheme for boundary condition with the multi-relaxation-time lattice Boltzmann method, this paper finds that the stability of the multi-relaxation-time model can be improv...By coupling the non-equilibrium extrapolation scheme for boundary condition with the multi-relaxation-time lattice Boltzmann method, this paper finds that the stability of the multi-relaxation-time model can be improved greatly, especially on simulating high Reynolds number (Re) flow. As a discovery, the super-stability analysed by Lallemand and Luo is verified and the complex structure of the cavity flow is also exhibited in our numerical simulation when Re is high enough. To the best knowledge of the authors, the maximum of Re which has been investigated by direct numerical simulation is only around 50 000 in the literature; however, this paper can readily extend the maximum to 1000 000 with the above combination.展开更多
AIM: To evaluate the impact of computed b = 1400 s/mm2(C-b1400) vs measured b = 1400 s/mm2(M-b1400) diffusion-weighted images(DWI) on lesion detection rate, image quality and quality of lesion demarcation using a mode...AIM: To evaluate the impact of computed b = 1400 s/mm2(C-b1400) vs measured b = 1400 s/mm2(M-b1400) diffusion-weighted images(DWI) on lesion detection rate, image quality and quality of lesion demarcation using a modern 3T-MR system based on a small-field-of-view sequence(sFOV). METHODS: Thirty patients(PSA: 9.5 ± 8.7 ng/mL; 68 ± 12 years) referred for magnetic resonance imaging(MRI) of the prostate were enrolled in this study. All measurements were performed on a 3T MR system.For DWI, a single-shot EPI diffusion sequence(b = 0, 100, 400, 800 s/mm2) was utilized. C-b1400 was cal-culated voxelwise from the ADC and diffusion images. Additionally, M-b1400 was acquired for evaluation and comparison. Lesion detection rate and maximum lesion diameters were obtained and compared. Image quality and quality of lesion demarcation were rated accord-ing to a 5-point Likert-type scale. Ratios of lesion-to-bladder as well as prostate-to-bladder signal intensity(SI) were calculated to estimate the signal-to-noise-ratio(SNR). RESULTS: Twenty-four lesions were detected on M-b1400 images and compared to C-b1400 images. C-b1400 detected three additional cancer suspicious lesions. Overall image quality was rated significantly better and SI ratios were significantly higher on C-b1400(2.3 ± 0.8 vs 3.1 ± 1.0, P < 0.001; 5.6 ± 1.8 vs 2.8 ± 0.9, P < 0.001). Comparison of lesion size showed no significant differences between C- and M-b1400(P = 0.22). CONCLUSION: Combination of a high b-value extrap-olation and sFOV may contribute to increase diagnostic accuracy of DWI without an increase of acquisition time, which may be useful to guide targeted prostate biopsies and to improve quality of multiparametric MRI(mMRI) especially under economical aspects in a pri-vate practice setting.展开更多
Biologic therapy, such as those that target tumor necrosis factor(TNF) signaling, has proven to be an efficacious method of treatment for patients with inflammatory bowel disease(IBD) with regards to symptom managemen...Biologic therapy, such as those that target tumor necrosis factor(TNF) signaling, has proven to be an efficacious method of treatment for patients with inflammatory bowel disease(IBD) with regards to symptom management and mucosal healing. However, the rising prevalence of IBD worldwide and the everincreasing burden of biologic pharmaceuticals in the health care industry is alarming for insurance companies, clinicians, and patients. The impending patent expiry and the relatively high costs of biologics, particularly anti-TNF agents, have paved the way for biosimilar development for IBD. The United States Food and Drug Administration defines a biosimilar as a biological product that is highly similar to its reference medicinal product, with no clinically meaningful differences in terms of safety, purity, and potency. The hope with biosimilars is that their entry into the market will be able to drive competition between pharmaceutical companies to reduce prices like that of the generic market, and that access to appropriate biologic treatments for IBD patients is increased in the long-term. Yet, there are challenging issues such as indication extrapolation and interchangeability that are still being debated in the field of IBD and must be addressed in future issued guidance. This review will discuss the issues and implications concerning the use of biosimilar therapy for IBD.展开更多
To enhance the resolution of parameter estimation with limited samples received by a short passive array, an iterative nonparametric algorithm for estimating the frequencies and direction-of-arrivals (DOAs) of signa...To enhance the resolution of parameter estimation with limited samples received by a short passive array, an iterative nonparametric algorithm for estimating the frequencies and direction-of-arrivals (DOAs) of signals is proposed. The cost function is constructed using 12-norm Gaussian entropy combined with an additional constraint, 12-norm constraint or linear constraint. By minimizing the cost functions in the temporal and the spatial dimensions using corresponding iteration algorithms respectively, the sparse discrete Fourier transforms (DFTs) of temporal and spatial samples are obtained to represent the extrapolated sequences with much larger sizes than the original samples. Then frequency and angle estimates are obtained by performing the traditional simple methods on the extrapolated sequences. It is shown that the proposed algorithm offers increased resolution and significantly reduced sidelobes compared with the periodogram and beamforming based methods. And it achieves high precision compared with the high-resolution method with lower computational burden. Some numerical simulations and real data processing results are presented to verify the effectiveness of the method.展开更多
The steadily growing traffic load has resulted in lots of bridge collapse events over the past decades, especiallyfor short-to-medium span bridges. This study investigated probabilistic and dynamic traffic load effect...The steadily growing traffic load has resulted in lots of bridge collapse events over the past decades, especiallyfor short-to-medium span bridges. This study investigated probabilistic and dynamic traffic load effects on shortto-medium span bridges using practical heavy traffic data in China. Mathematical formulations for traffic-bridgecoupled vibration and probabilistic extrapolation were derived. A framework for extrapolating probabilistic anddynamic traffic load effect was presented to conduct an efficient and accurate extrapolation. An equivalent dynamicwheel load model was demonstrated to be feasible for short-to-medium span bridges. Numerical studies of twotypes of simply-supported bridges were conducted based on site-specific traffic monitoring data. Numerical resultsshow that the simulated samples and fitting lines follow a curve line in the Gumbel distribution coordinate system. Itcan be assumed that dynamic traffic load effects follow Gaussian distribution and the extreme value follows Gumbeldistribution. The equivalent probabilistic amplification factor is smaller than the individual dynamic amplificationfactor, which might be due to the variability of individual samples. Eurocode 1 is the most conservative specificationon vehicle load models, followed by the BS5400 specification. The D60-2015 specification in China and ASSHTOspecification provide lower conservative traffic load models.展开更多
This paper formulates two different boundary-element+Born series schemes for wave propagation simulation in multilayered media by incorporating a Born series and boundary integral equations. The first scheme directly...This paper formulates two different boundary-element+Born series schemes for wave propagation simulation in multilayered media by incorporating a Born series and boundary integral equations. The first scheme directly decomposes the resulting boundary integral equation matrix into the self-interaction operators associated with each boundary itself and the extrapolation operators expressing cross-interactions between different boundaries in a subregion. For the second scheme, the matrix dimension is firstly reduced to a half by the elimination of the traction field in the equations. The resulting new matrix can also be split into the self-interaction matrices associated each subregion itself and the extrapolation matrices interpreting cross-interactions between different subregions in a whole model. Both the numerical schemes avoid the inversion of the relatively much larger boundary integral equation matrix of a full-waveform BE method and hence save computing time and memory greatly. The two schemes are validated by calculating synthetic seismograms for a homogeneous layered model, compared with the full-waveform BE numerical solution. Numerical experiments indicate that both the BEM+Born series modeling schemes are valid and effective. The tests also confirm that the second modeling scheme has a faster convergence in comparison with the first one.展开更多
The quasi-Shannon interval wavelet is constructed based on the interpolation wavelet theory, and an adaptive precise integration method, which is based on extrapolation method is presented for nonlinear ordinary diffe...The quasi-Shannon interval wavelet is constructed based on the interpolation wavelet theory, and an adaptive precise integration method, which is based on extrapolation method is presented for nonlinear ordinary differential equations ( ODEs). And then, an adaptive interval wavelet precise integration method (AIWPIM) for nonlinear partial differential equations(PDEs) is proposed. The numerical results show that the computational precision of AIWPIM is higher than that of the method constructed by combining the wavelet and the 4th Runge-Kutta method, and the computational amounts of these two methods are almost equal. For convenience, the Burgers equation is taken as an example in introducing this method, which is also valid for more general cases.展开更多
To realize high-resolution digital beamforming(DBF)of ultra-wideband(UWB) signals, we propose a DBF method based on Carath ′eodory representation for delay compensation and array extrapolation. Delay compensation by ...To realize high-resolution digital beamforming(DBF)of ultra-wideband(UWB) signals, we propose a DBF method based on Carath ′eodory representation for delay compensation and array extrapolation. Delay compensation by Carath ′eodory representation could achieve high interpolation accuracy while using the single channel sampling technique. Array extrapolation by Carath ′eodory representation reformulates and extends each snapshot, consequently extends the aperture of the original uniform linear array(ULA) by several times and provides a better realtime performance than the existing aperture extrapolation utilizing vector extrapolation based on the two dimensional autoregressive(2-D AR) model. The UWB linear frequency modulated(LFM) signal is used for simulation analysis. Simulation results demonstrate that the proposed method is featured by a much higher spatial resolution than traditional DBF methods and lower sidelobes than using Lagrange fractional filters.展开更多
文摘This paper studies a strongly convergent inertial forward-backward-forward algorithm for the variational inequality problem in Hilbert spaces.In our convergence analysis,we do not assume the on-line rule of the inertial parameters and the iterates,which have been assumed by several authors whenever a strongly convergent algorithm with an inertial extrapolation step is proposed for a variational inequality problem.Consequently,our proof arguments are different from what is obtainable in the relevant literature.Finally,we give numerical tests to confirm the theoretical analysis and show that our proposed algorithm is superior to related ones in the literature.
基金supported by National major special equipment development(No.2011YQ120045)The National Natural Science Fund(No.41074050 and 41304023)
文摘We use the extrapolated Tikhonov regularization to deal with the ill-posed problem of 3D density inversion of gravity gradient data. The use of regularization parameters in the proposed method reduces the deviations between calculated and observed data. We also use the depth weighting function based on the eigenvector of gravity gradient tensor to eliminate undesired effects owing to the fast attenuation of the position function. Model data suggest that the extrapolated Tikhonov regularization in conjunction with the depth weighting function can effectively recover the 3D distribution of density anomalies. We conduct density inversion of gravity gradient data from the Australia Kauring test site and compare the inversion results with the published research results. The proposed inversion method can be used to obtain the 3D density distribution of underground anomalies.
基金supported by the National Scientific and Technological Plan(Nos.2009BAB43B00 and 2009BAB43B01)
文摘Tikhonov regularization(TR) method has played a very important role in the gravity data and magnetic data process. In this paper, the Tikhonov regularization method with respect to the inversion of gravity data is discussed. and the extrapolated TR method(EXTR) is introduced to improve the fitting error. Furthermore, the effect of the parameters in the EXTR method on the fitting error, number of iterations, and inversion results are discussed in details. The computation results using a synthetic model with the same and different densities indicated that. compared with the TR method, the EXTR method not only achieves the a priori fitting error level set by the interpreter but also increases the fitting precision, although it increases the computation time and number of iterations. And the EXTR inversion results are more compact than the TR inversion results, which are more divergent. The range of the inversion data is closer to the default range of the model parameters, and the model features and default model density distribution agree well.
文摘Autoregressive (AR) modeling is applied to data extrapolation of radio frequency (RF) echo signals, and Burg algorithm, which can be computed in small amount and lead to a stable prediction filter, is used to estimate the prediction parameters of AR modeling. The complex data samples are directly extrapolated to obtain the extrapolated echo data in the frequency domain. The small rotating angle data extrapolation and the large rotating angular data extrapolation are considered separately in azimuth domain. The method of data extrapolation for the small rotating angle is the same as that in frequency domain, while the amplitude samples of large rotating angle echo data are extrapolated to obtain extrapolated echo amplitude, and the complex data of large rotating angle echo samples are extrapolated to get the extrapolated echo phase respectively. The calculation results show that the extrapolated echo data obtained by the above mentioned methods are accurate.
基金supported under the framework of international cooperation program managed by the National Research Foundation of Korea(NRF 2020K2A9A2A06069972,FY2020)supported by the BK21 FOUR(Fostering Outstanding Universities for Research)funded by the Ministry of Education of the Republic of Korea and National Research Foundation of Korea(NRF)supported by the Ministry of Education of the Republic of Korea and the National Research Foundation of Korea(NRF-2020S1A5B8103855).
文摘This paper deals with the recommendation system in the so-called user-centric payment environment where users,i.e.,the payers,can make payments without providing self-information to merchants.This service maintains only the minimum purchase information such as the purchased product names,the time of purchase,the place of purchase for possible refunds or cancellations of purchases.This study aims to develop AI-based recommendation system by utilizing the minimum transaction data generated by the user-centric payment service.First,we developed a matrix-based extrapolative collaborative filtering algorithm based on open transaction data.The recommendation methodology was verified with the real transaction data.Based on the experimental results,we confirmed that the recommendation performance is satisfactory only with the minimum purchase information.
基金supported by the National Natural Science Foundation of China (21263015,21567016 and 21503106)the Education Department Foundation of Jiangxi Province (KJLD14005 and GJJ150016)the Natural Science Foundation of Jiangxi Province (20142BAB213013 and 20151BBE50006),which are greatly acknowledged by the authors~~
文摘A series of SnO2‐based catalysts modified by Mn, Zr, Ti and Pb oxides with a Sn/M (M=Mn, Zr, Ti and Pb) molar ratio of 9/1 were prepared by a co‐precipitation method and used for CH4 and CO oxidation. The Mn3+, Zr4+, Ti4+and Pb4+cations are incorporated into the lattice of tetragonal rutile SnO2 to form a solid solution structure. As a consequence, the surface area and thermal stability of the catalysts are improved. Moreover, the oxygen species of the modified catalysts become easier to be reduced. Therefore, the oxidation activity over the catalysts was improved, except for the one modified by Pb oxide. Manganese oxide demonstrates the best promotional effects for SnO2. Using an X‐ray diffraction extrapolation method, the lattice capacity of SnO2 for Mn2O3 was 0.135 g Mn2O3/g SnO2, which indicates that to form stable solid solution, only 21%Sn4+cations in the lattice can be maximally replaced by Mn3+. If the amount of Mn3+cations is over the capacity, Mn2O3 will be formed, which is not favorable for the activity of the catalysts. The Sn rich samples with only Sn‐Mn solid solution phase show higher activity than the ones with excess Mn2O3 species.
基金This study was provided by Natural Science Foundation of Guangdong Province under Grant No. 5001121the China Meteorological Administration under Grant Nos. CMATG2005Y05 and CMATG2008Z10the Guangdong Meteorological Bureau under Grant Nos. 2007A2 and GRMC2007Z03
文摘Extending the lead time of precipitation nowcasts is vital to improvements in heavy rainfall warning, flood mitigation, and water resource management. Because the TREC vector (tracking radar echo by correlation) represents only the instantaneous trend of precipitation echo motion, the approach using derived echo motion vectors to extrapolate radar reflectivity as a rainfall forecast is not satisfactory if the lead time is beyond 30 minutes. For longer lead times, the effect of ambient winds on echo movement should be considered. In this paper, an extrapolation algorithm that extends forecast lead times up to 3 hours was developed to blend TREC vectors with model-predicted winds. The TREC vectors were derived from radar reflectivity patterns in 3 km height CAPPI (constant altitude plan position indicator) mosaics through a cross-correlation technique. The background steering winds were provided by predictions of the rapid update assimilation model CHAF (cycle of hourly assimilation and forecast). A similarity index was designed to determine the vertical level at which model winds were applied in the extrapolation process, which occurs via a comparison between model winds and radar vectors. Based on a summer rainfall case study, it is found that the new algorithm provides a better forecast.
基金This study was supported by the Special Fund for Basic Research and Operation of Chinese Academy of Meteorological Science:Development on quantitative precipitation forecasts for 0-6 h lead times by blending radar-based extrapolation and GRAPES-meso,Observation and retrieval methods of micro-physics,the National Natural Science Foundation of China
文摘A new radar echo tracking algorithm known as multi-scale tracking radar echoes by cross-correlation (MTREC) was developed in this study to analyze movements of radar echoes at different spatial scales. Movement of radar echoes, particularly associated with convective storms, exhibits different characteristics at various spatial scales as a result of complex interactions among meteorological systems leading to the formation of convective storms. For the null echo region, the usual correlation technique produces zero or a very small magnitude of motion vectors. To mitigate these constraints, MTREC uses the tracking radar echoes by correlation (TREC) technique with a large "box" to determine the systematic movement driven by steering wind, and MTREC applies the TREC technique with a small "box" to estimate small-scale internal motion vectors. Eventually, the MTREC vectors are obtained by synthesizing the systematic motion and the small-scale internal motion. Performance of the MTREC technique was compared with TREC technique using case studies: the Khanun typhoon on 11 September 2005 observed by Wenzhou radar and a squall-line system on 23 June 2011 detected by Beijing radar. The results demonstrate that more spatially smoothed and continuous vector fields can be generated by the MTREC technique, which leads to improvements in tracking the entire radar reflectivity pattern. The new multi-scMe tracking scheme was applied to study its impact on the performance of quantitative precipitation nowcasting. The location and intensity of heavy precipitation at a 1-h lead time was more consistent with quantitative precipitation estimates using radar and rain gauges.
文摘In this paper we employ the Petrov Galerkin method for the parabolic problems to get the finite element approximate solution of high accuracy by means of the interpolation postprocessing, extrapolation and defect correction techniques.
基金Project supported by the National Natural Science Foundation of China (Grant No 70271069).
文摘By coupling the non-equilibrium extrapolation scheme for boundary condition with the multi-relaxation-time lattice Boltzmann method, this paper finds that the stability of the multi-relaxation-time model can be improved greatly, especially on simulating high Reynolds number (Re) flow. As a discovery, the super-stability analysed by Lallemand and Luo is verified and the complex structure of the cavity flow is also exhibited in our numerical simulation when Re is high enough. To the best knowledge of the authors, the maximum of Re which has been investigated by direct numerical simulation is only around 50 000 in the literature; however, this paper can readily extend the maximum to 1000 000 with the above combination.
文摘AIM: To evaluate the impact of computed b = 1400 s/mm2(C-b1400) vs measured b = 1400 s/mm2(M-b1400) diffusion-weighted images(DWI) on lesion detection rate, image quality and quality of lesion demarcation using a modern 3T-MR system based on a small-field-of-view sequence(sFOV). METHODS: Thirty patients(PSA: 9.5 ± 8.7 ng/mL; 68 ± 12 years) referred for magnetic resonance imaging(MRI) of the prostate were enrolled in this study. All measurements were performed on a 3T MR system.For DWI, a single-shot EPI diffusion sequence(b = 0, 100, 400, 800 s/mm2) was utilized. C-b1400 was cal-culated voxelwise from the ADC and diffusion images. Additionally, M-b1400 was acquired for evaluation and comparison. Lesion detection rate and maximum lesion diameters were obtained and compared. Image quality and quality of lesion demarcation were rated accord-ing to a 5-point Likert-type scale. Ratios of lesion-to-bladder as well as prostate-to-bladder signal intensity(SI) were calculated to estimate the signal-to-noise-ratio(SNR). RESULTS: Twenty-four lesions were detected on M-b1400 images and compared to C-b1400 images. C-b1400 detected three additional cancer suspicious lesions. Overall image quality was rated significantly better and SI ratios were significantly higher on C-b1400(2.3 ± 0.8 vs 3.1 ± 1.0, P < 0.001; 5.6 ± 1.8 vs 2.8 ± 0.9, P < 0.001). Comparison of lesion size showed no significant differences between C- and M-b1400(P = 0.22). CONCLUSION: Combination of a high b-value extrap-olation and sFOV may contribute to increase diagnostic accuracy of DWI without an increase of acquisition time, which may be useful to guide targeted prostate biopsies and to improve quality of multiparametric MRI(mMRI) especially under economical aspects in a pri-vate practice setting.
文摘Biologic therapy, such as those that target tumor necrosis factor(TNF) signaling, has proven to be an efficacious method of treatment for patients with inflammatory bowel disease(IBD) with regards to symptom management and mucosal healing. However, the rising prevalence of IBD worldwide and the everincreasing burden of biologic pharmaceuticals in the health care industry is alarming for insurance companies, clinicians, and patients. The impending patent expiry and the relatively high costs of biologics, particularly anti-TNF agents, have paved the way for biosimilar development for IBD. The United States Food and Drug Administration defines a biosimilar as a biological product that is highly similar to its reference medicinal product, with no clinically meaningful differences in terms of safety, purity, and potency. The hope with biosimilars is that their entry into the market will be able to drive competition between pharmaceutical companies to reduce prices like that of the generic market, and that access to appropriate biologic treatments for IBD patients is increased in the long-term. Yet, there are challenging issues such as indication extrapolation and interchangeability that are still being debated in the field of IBD and must be addressed in future issued guidance. This review will discuss the issues and implications concerning the use of biosimilar therapy for IBD.
基金supported by the Program for New Century Excellent Talents in University (NCET-06-0856)the National Natural Science Foundation of China (60772068)
文摘To enhance the resolution of parameter estimation with limited samples received by a short passive array, an iterative nonparametric algorithm for estimating the frequencies and direction-of-arrivals (DOAs) of signals is proposed. The cost function is constructed using 12-norm Gaussian entropy combined with an additional constraint, 12-norm constraint or linear constraint. By minimizing the cost functions in the temporal and the spatial dimensions using corresponding iteration algorithms respectively, the sparse discrete Fourier transforms (DFTs) of temporal and spatial samples are obtained to represent the extrapolated sequences with much larger sizes than the original samples. Then frequency and angle estimates are obtained by performing the traditional simple methods on the extrapolated sequences. It is shown that the proposed algorithm offers increased resolution and significantly reduced sidelobes compared with the periodogram and beamforming based methods. And it achieves high precision compared with the high-resolution method with lower computational burden. Some numerical simulations and real data processing results are presented to verify the effectiveness of the method.
基金The research was supported by the National Science Foundation of China(Grant No.51908068)the support from the Key Laboratory of Bridge Engineering Safety Control by Department of Education(Changsha University of Science&Technology).Industry Key Laboratory of Traffic Infrastructure Security Risk Management in Changsha University of Science and Technology(Grant Nos.19KF03,19KB02)Open Fund of Engineering Research Center of Catastrophic Prophylaxis and Treatment of Road&Traffic Safety of Ministry of Education(Grant No.KFJ190403).
文摘The steadily growing traffic load has resulted in lots of bridge collapse events over the past decades, especiallyfor short-to-medium span bridges. This study investigated probabilistic and dynamic traffic load effects on shortto-medium span bridges using practical heavy traffic data in China. Mathematical formulations for traffic-bridgecoupled vibration and probabilistic extrapolation were derived. A framework for extrapolating probabilistic anddynamic traffic load effect was presented to conduct an efficient and accurate extrapolation. An equivalent dynamicwheel load model was demonstrated to be feasible for short-to-medium span bridges. Numerical studies of twotypes of simply-supported bridges were conducted based on site-specific traffic monitoring data. Numerical resultsshow that the simulated samples and fitting lines follow a curve line in the Gumbel distribution coordinate system. Itcan be assumed that dynamic traffic load effects follow Gaussian distribution and the extreme value follows Gumbeldistribution. The equivalent probabilistic amplification factor is smaller than the individual dynamic amplificationfactor, which might be due to the variability of individual samples. Eurocode 1 is the most conservative specificationon vehicle load models, followed by the BS5400 specification. The D60-2015 specification in China and ASSHTOspecification provide lower conservative traffic load models.
基金supported by National Natural Science Foundation of China (No.40830423)National Basic Research Program of China(973 Program,2009CB219403)
文摘This paper formulates two different boundary-element+Born series schemes for wave propagation simulation in multilayered media by incorporating a Born series and boundary integral equations. The first scheme directly decomposes the resulting boundary integral equation matrix into the self-interaction operators associated with each boundary itself and the extrapolation operators expressing cross-interactions between different boundaries in a subregion. For the second scheme, the matrix dimension is firstly reduced to a half by the elimination of the traction field in the equations. The resulting new matrix can also be split into the self-interaction matrices associated each subregion itself and the extrapolation matrices interpreting cross-interactions between different subregions in a whole model. Both the numerical schemes avoid the inversion of the relatively much larger boundary integral equation matrix of a full-waveform BE method and hence save computing time and memory greatly. The two schemes are validated by calculating synthetic seismograms for a homogeneous layered model, compared with the full-waveform BE numerical solution. Numerical experiments indicate that both the BEM+Born series modeling schemes are valid and effective. The tests also confirm that the second modeling scheme has a faster convergence in comparison with the first one.
文摘The quasi-Shannon interval wavelet is constructed based on the interpolation wavelet theory, and an adaptive precise integration method, which is based on extrapolation method is presented for nonlinear ordinary differential equations ( ODEs). And then, an adaptive interval wavelet precise integration method (AIWPIM) for nonlinear partial differential equations(PDEs) is proposed. The numerical results show that the computational precision of AIWPIM is higher than that of the method constructed by combining the wavelet and the 4th Runge-Kutta method, and the computational amounts of these two methods are almost equal. For convenience, the Burgers equation is taken as an example in introducing this method, which is also valid for more general cases.
基金supported by the National Natural Science Foundation of China(61271331 61571229)
文摘To realize high-resolution digital beamforming(DBF)of ultra-wideband(UWB) signals, we propose a DBF method based on Carath ′eodory representation for delay compensation and array extrapolation. Delay compensation by Carath ′eodory representation could achieve high interpolation accuracy while using the single channel sampling technique. Array extrapolation by Carath ′eodory representation reformulates and extends each snapshot, consequently extends the aperture of the original uniform linear array(ULA) by several times and provides a better realtime performance than the existing aperture extrapolation utilizing vector extrapolation based on the two dimensional autoregressive(2-D AR) model. The UWB linear frequency modulated(LFM) signal is used for simulation analysis. Simulation results demonstrate that the proposed method is featured by a much higher spatial resolution than traditional DBF methods and lower sidelobes than using Lagrange fractional filters.