As a highly integrative and demanding receptive skill,listening comprehension presents a challenge to both learners and researchers.The study reported in this paper is listening comprehension objective-factor research...As a highly integrative and demanding receptive skill,listening comprehension presents a challenge to both learners and researchers.The study reported in this paper is listening comprehension objective-factor research.Manipulating topic factors,the study investigated the effect of topic familiarity and linguistic difficulty on EFL(English as a foreign language)listening comprehension of learners at different proficiency levels.展开更多
Objective This study is to examine the influence of familiarity on energy intake, eating behavior, and concentration of the plasma gut hormones in lean and overweight young male subjects. Methods Twenty-eight lean and...Objective This study is to examine the influence of familiarity on energy intake, eating behavior, and concentration of the plasma gut hormones in lean and overweight young male subjects. Methods Twenty-eight lean and twenty-eight overweight participants were recruited. Their food consumption was documented and analyzed when they had a test meal while they were paired with friends or strangers at the same weight stature. Their eating behavior was recorded with cameras hidden in the carton, and postprandial plasma gut hormone concentration were measured. Results Compared with overweight strangers(OS), overweight friends(OF) had increased food consumption, prolonged and decreased number of chews per 10 g food. Compared with OS, postprandial plasma concentration of cholecystokinin-8 was significantly lower in OF group at 30, 60, and 90 min, whereas the concentration of glucagon-like peptide 1 was significantly lower at 60 and 90 min. Plasma ghrelin concentration was significantly higher in the OF group than that in the OS group at 90 and 120 min. No significant differences in gut hormone concentration were observed between lean strangers(LS) and lean friends(LF) groups at all time points. Conclusion Familiarity plays an important role in increasing energy intake and in changing of postprandial gut hormone concentration in overweight individuals.展开更多
With the rapid development of social networks, there is a focus on marketing strategies and business models that are based on social media. In the academic world, scholars believe that online trust is a key factor con...With the rapid development of social networks, there is a focus on marketing strategies and business models that are based on social media. In the academic world, scholars believe that online trust is a key factor contributing to online purchasing behavior. This article explored several factors in social media trust and verified the moderating role of offline familiarity by using relevant research on online trust in conjunction with a structure equation model. The results show that independent variables such as reputation, SNS interaction, information quality, reciprocity, satisfaction and shared values have a positive influence on trust, whereas perceived similarity does not, and information quality is the most important factor. In addition, offline familiarity significantly moderates the relations between information quality, reciprocity, reputation, shared values and social media trust. This information is important to assist companies in developing an effective social network marketing strategy.展开更多
Idiopathic nondementing Parkinson’s disease (PD) is marked by progressive loss of dopaminergic neurons in the substantia nigra pars compacta and ventral tegmental area. Recent brain imaging work implicates these stru...Idiopathic nondementing Parkinson’s disease (PD) is marked by progressive loss of dopaminergic neurons in the substantia nigra pars compacta and ventral tegmental area. Recent brain imaging work implicates these structures in dopamine modulated networks subserving episodic memory. These findings are of relevance to PD because they suggest that dopamine depletion contributes to the disease-dependent decline in episodic memory, and therefore, this decline should, at least partially, be remediated by dopaminergic medication. Recognition memory (RM), recollection and familiarity during recognition was examined in 17 PD patients, 12 of whom were medicated with a D2 dopamine agonist (pramipexole or ropinirole) and l-dopa, with a further 5 PD control patients on l-dopa but no D2 agonist. Memory was tested “ON” and, following a period of medication withdrawal, “OFF” and compared to a group of 14 matched healthy volunteers (HV). The HVs were also tested twice in the absence of medication. The patients on the agonists PD showed significant impairments in recollection ON- and OFF-medication, whereas the l-dopa control patients exhibited a decline in OFF-recollection only. RM and familiarity were spared in both groups ON- and OFF-medication. These findings suggest that D2 dopamine agonists (combined with l-dopa) contribute to disease-dependent episodic memory impairment.展开更多
Ease of use is one of the main criteria that customers consider when making a purchase decision.To provide a pleasant experience to the customers,offering products or services consisting of advanced features and funct...Ease of use is one of the main criteria that customers consider when making a purchase decision.To provide a pleasant experience to the customers,offering products or services consisting of advanced features and functions is no longer enough,due to the existing competition in the global market.In reality,the ease of use of any product is influenced by the conditions of the product and the familiarity of the user.This study examines the influence of the familiarity and the product conditions on the ease of use of a product.This only explains how the conditions of the product and the familiarity of the user,influence on the ease of use of a product when the usage hours of a product increases.A case study would be conducted to validate the results.The results of this study indicate that in the case where both the product conditions and the familiarity has been varied,the ease of use of the product has been increased from 0.229 to 0.380 gradually within the 10 weeks period.Through these results valuable guidance could be obtained by the manufacturers to identify how the ease of use level of a product deviates from the standard level when the usage hours of the product would increase.展开更多
The high-quality development of tourism aims to improve tourists'sense of well-being and fulfillment.The improvement of tourists'sense of well-being will not only enable tourists to obtain positive emotional e...The high-quality development of tourism aims to improve tourists'sense of well-being and fulfillment.The improvement of tourists'sense of well-being will not only enable tourists to obtain positive emotional experiences but is also an important way to improve their quality of life.However,the existing research has not yet reached a clear conclusion on how tourists'sense of well-being is formed,whether tourists'sense of well-being will spill over(i.e.,knowledge sharing)after tourists obtain it,and whether the destination familiarity brought by the spillover of sense of well-being(i.e.,knowledge sharing)will affect other tourists.Therefore,based on the experience marketing theory and the embodiment theory,this paper empirically examines the formation and spillover effect of tourists'sense of well-being through structural equation modeling(SEM).The research shows that:(a)Subject presence has a positive effect on tourists'sense of well-being,which further promotes knowledge sharing and realizes the spillover of tourists'sense of well-being,and tourists'sense of well-being plays a mediating role between subject presence and knowledge sharing;(b)Destination familiarity resulting from the spillover of sense of wellbeing(i.e.,knowledge sharing)plays a negative moderating role in the positive impact of subject presence on tourists'sense of well-being.This paper not only expands the boundaries of research on tourists'sense of well-being and embodiment theory to some extent but also provides theoretical support and countermeasures for the high-quality development of China's tourism and even service industry.展开更多
Destination familiarity is an important non-economic determinant of tourists’destination choice that has not been adequately studied.This study posits a literary dimension to the concept of destination familiarity—t...Destination familiarity is an important non-economic determinant of tourists’destination choice that has not been adequately studied.This study posits a literary dimension to the concept of destination familiarity—that is,the extent to which tourists have gained familiarity with a given destination through literature—and seeks to investigate the impact of this form of familiarity on inbound tourism to China's Mainland.Employing the English fiction dataset of the Google Books corpus,the New York Times annotated corpus,and the Time magazine corpus,we construct two types of destination familiarity based on literary texts:affectionbased destination familiarity and knowledge-based destination familiarity.The results from dynamic panel estimation(1994–2004)demonstrate that the higher the degree of affection-based destination familiarity with a province in the previous year,the larger the number of inbound tourists the following year.Examining the influence of literature and its consumption on tourism activities sheds light on the dynamics of sustainable tourism development in emerging markets.展开更多
The spectrum user’s librarys containing 1533 familiar toxicants have been built; A method with high separability and sensitivity has been found,The RT and the detection limit of 210 familiar abuse drugs has been conf...The spectrum user’s librarys containing 1533 familiar toxicants have been built; A method with high separability and sensitivity has been found,The RT and the detection limit of 210 familiar abuse drugs has been confirmed; the processing methods to analyse spectrum data automatically have been found; It is simple,quick,sensitive and reliable,and can take place of manual operation,It is very useful to screen the familiar toxicants in unkown sample.展开更多
Several investigations have shown that emotional events show superior recall than non-emotional ones. However, the cortical mechanisms underlying the episodic recall of emotional scenes are still poorly understood. Ou...Several investigations have shown that emotional events show superior recall than non-emotional ones. However, the cortical mechanisms underlying the episodic recall of emotional scenes are still poorly understood. Our main aim was to compare the magnitude of the Event-Related brain Potentials (ERP) old-new effect related to emotionally unpleasant, pleasant and neutral photographic images. As expected, correct recognition of all types of images elicited three topographically distinct ERP components sensitive to the classical old-new recognition effect. The results revealed that the behavioral performances were mainly sensitive to arousal, while the ERP old/new effect over posterior regions (300 - 1000 ms) was exclusively affected by unpleasantness. A later component (1000 - 1400 ms) showed an inverted old/ new effect at parietal sites, which was also sensitive to unpleasantness. These results imply that ERP reflecting episodic conscious recollection and post-retrieval monitoring are clearly affected both by valence and arousal.展开更多
The choice of reading materials partly decides the effectiveness of classroom reading instructions in TESL.This paper analyses the cognitive process of reading and some problems in classroom reading instructions of re...The choice of reading materials partly decides the effectiveness of classroom reading instructions in TESL.This paper analyses the cognitive process of reading and some problems in classroom reading instructions of reading course,and suggests three basic principles for choosing reading materials,including the principle of comprehensibility reading materials,readers’familiarity with the topics of the reading materials,and the sufficiency of reading materials.展开更多
Emery dreifuss muscular dystrophy(EDMD) is a rare genetic syndrome consisting of tendon retractions,progressive muscle atrophy and cardiac involvement.We report a case of an obese patient affected by the familial X-li...Emery dreifuss muscular dystrophy(EDMD) is a rare genetic syndrome consisting of tendon retractions,progressive muscle atrophy and cardiac involvement.We report a case of an obese patient affected by the familial X-linked form in which a pericallosal lipoma was found during investigation for a suspected acute vasculopathy.To date,EDMD has never been associated with cerebral lipomas and the X-linked form was never considered to be involved in lipodystrophic syndromes or non-muscular conditions.Our case confirms the variable expressivity of the disease and suggests a possible role of Emerin in the intranuclear regulation of signals for adipocyte cell differentiation.展开更多
Dilated cardiomyopathy(DCM)is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM...Dilated cardiomyopathy(DCM)is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM concomitant with arrhythmias and sudden death resulting from gene mutation has been widely展开更多
文摘As a highly integrative and demanding receptive skill,listening comprehension presents a challenge to both learners and researchers.The study reported in this paper is listening comprehension objective-factor research.Manipulating topic factors,the study investigated the effect of topic familiarity and linguistic difficulty on EFL(English as a foreign language)listening comprehension of learners at different proficiency levels.
基金supported by the Scientific Research Fund Project of Qiqihar Medical University under grant No.QY2016M-17.The study of social effects on energy intake and plasma gut hormone concentration
文摘Objective This study is to examine the influence of familiarity on energy intake, eating behavior, and concentration of the plasma gut hormones in lean and overweight young male subjects. Methods Twenty-eight lean and twenty-eight overweight participants were recruited. Their food consumption was documented and analyzed when they had a test meal while they were paired with friends or strangers at the same weight stature. Their eating behavior was recorded with cameras hidden in the carton, and postprandial plasma gut hormone concentration were measured. Results Compared with overweight strangers(OS), overweight friends(OF) had increased food consumption, prolonged and decreased number of chews per 10 g food. Compared with OS, postprandial plasma concentration of cholecystokinin-8 was significantly lower in OF group at 30, 60, and 90 min, whereas the concentration of glucagon-like peptide 1 was significantly lower at 60 and 90 min. Plasma ghrelin concentration was significantly higher in the OF group than that in the OS group at 90 and 120 min. No significant differences in gut hormone concentration were observed between lean strangers(LS) and lean friends(LF) groups at all time points. Conclusion Familiarity plays an important role in increasing energy intake and in changing of postprandial gut hormone concentration in overweight individuals.
文摘With the rapid development of social networks, there is a focus on marketing strategies and business models that are based on social media. In the academic world, scholars believe that online trust is a key factor contributing to online purchasing behavior. This article explored several factors in social media trust and verified the moderating role of offline familiarity by using relevant research on online trust in conjunction with a structure equation model. The results show that independent variables such as reputation, SNS interaction, information quality, reciprocity, satisfaction and shared values have a positive influence on trust, whereas perceived similarity does not, and information quality is the most important factor. In addition, offline familiarity significantly moderates the relations between information quality, reciprocity, reputation, shared values and social media trust. This information is important to assist companies in developing an effective social network marketing strategy.
文摘Idiopathic nondementing Parkinson’s disease (PD) is marked by progressive loss of dopaminergic neurons in the substantia nigra pars compacta and ventral tegmental area. Recent brain imaging work implicates these structures in dopamine modulated networks subserving episodic memory. These findings are of relevance to PD because they suggest that dopamine depletion contributes to the disease-dependent decline in episodic memory, and therefore, this decline should, at least partially, be remediated by dopaminergic medication. Recognition memory (RM), recollection and familiarity during recognition was examined in 17 PD patients, 12 of whom were medicated with a D2 dopamine agonist (pramipexole or ropinirole) and l-dopa, with a further 5 PD control patients on l-dopa but no D2 agonist. Memory was tested “ON” and, following a period of medication withdrawal, “OFF” and compared to a group of 14 matched healthy volunteers (HV). The HVs were also tested twice in the absence of medication. The patients on the agonists PD showed significant impairments in recollection ON- and OFF-medication, whereas the l-dopa control patients exhibited a decline in OFF-recollection only. RM and familiarity were spared in both groups ON- and OFF-medication. These findings suggest that D2 dopamine agonists (combined with l-dopa) contribute to disease-dependent episodic memory impairment.
文摘Ease of use is one of the main criteria that customers consider when making a purchase decision.To provide a pleasant experience to the customers,offering products or services consisting of advanced features and functions is no longer enough,due to the existing competition in the global market.In reality,the ease of use of any product is influenced by the conditions of the product and the familiarity of the user.This study examines the influence of the familiarity and the product conditions on the ease of use of a product.This only explains how the conditions of the product and the familiarity of the user,influence on the ease of use of a product when the usage hours of a product increases.A case study would be conducted to validate the results.The results of this study indicate that in the case where both the product conditions and the familiarity has been varied,the ease of use of the product has been increased from 0.229 to 0.380 gradually within the 10 weeks period.Through these results valuable guidance could be obtained by the manufacturers to identify how the ease of use level of a product deviates from the standard level when the usage hours of the product would increase.
基金supported by the Sichuan Social Science Planning Project (General Project)“Research on the Development of Rural Tourism Sharing Economy in Sichuan from the Perspective of Rural Revitalization Strategy and All-for-one Tourism” (SC20B133)the Humanities and Social Sciences Research Special Fund Cultivation Project (2022-2023RW021)of Southwest Petroleum University。
文摘The high-quality development of tourism aims to improve tourists'sense of well-being and fulfillment.The improvement of tourists'sense of well-being will not only enable tourists to obtain positive emotional experiences but is also an important way to improve their quality of life.However,the existing research has not yet reached a clear conclusion on how tourists'sense of well-being is formed,whether tourists'sense of well-being will spill over(i.e.,knowledge sharing)after tourists obtain it,and whether the destination familiarity brought by the spillover of sense of well-being(i.e.,knowledge sharing)will affect other tourists.Therefore,based on the experience marketing theory and the embodiment theory,this paper empirically examines the formation and spillover effect of tourists'sense of well-being through structural equation modeling(SEM).The research shows that:(a)Subject presence has a positive effect on tourists'sense of well-being,which further promotes knowledge sharing and realizes the spillover of tourists'sense of well-being,and tourists'sense of well-being plays a mediating role between subject presence and knowledge sharing;(b)Destination familiarity resulting from the spillover of sense of wellbeing(i.e.,knowledge sharing)plays a negative moderating role in the positive impact of subject presence on tourists'sense of well-being.This paper not only expands the boundaries of research on tourists'sense of well-being and embodiment theory to some extent but also provides theoretical support and countermeasures for the high-quality development of China's tourism and even service industry.
基金This work was supported in part by the Tsinghua University Initiative Scientific Research Program(No.2019THZWLJ29).
文摘Destination familiarity is an important non-economic determinant of tourists’destination choice that has not been adequately studied.This study posits a literary dimension to the concept of destination familiarity—that is,the extent to which tourists have gained familiarity with a given destination through literature—and seeks to investigate the impact of this form of familiarity on inbound tourism to China's Mainland.Employing the English fiction dataset of the Google Books corpus,the New York Times annotated corpus,and the Time magazine corpus,we construct two types of destination familiarity based on literary texts:affectionbased destination familiarity and knowledge-based destination familiarity.The results from dynamic panel estimation(1994–2004)demonstrate that the higher the degree of affection-based destination familiarity with a province in the previous year,the larger the number of inbound tourists the following year.Examining the influence of literature and its consumption on tourism activities sheds light on the dynamics of sustainable tourism development in emerging markets.
文摘The spectrum user’s librarys containing 1533 familiar toxicants have been built; A method with high separability and sensitivity has been found,The RT and the detection limit of 210 familiar abuse drugs has been confirmed; the processing methods to analyse spectrum data automatically have been found; It is simple,quick,sensitive and reliable,and can take place of manual operation,It is very useful to screen the familiar toxicants in unkown sample.
文摘Several investigations have shown that emotional events show superior recall than non-emotional ones. However, the cortical mechanisms underlying the episodic recall of emotional scenes are still poorly understood. Our main aim was to compare the magnitude of the Event-Related brain Potentials (ERP) old-new effect related to emotionally unpleasant, pleasant and neutral photographic images. As expected, correct recognition of all types of images elicited three topographically distinct ERP components sensitive to the classical old-new recognition effect. The results revealed that the behavioral performances were mainly sensitive to arousal, while the ERP old/new effect over posterior regions (300 - 1000 ms) was exclusively affected by unpleasantness. A later component (1000 - 1400 ms) showed an inverted old/ new effect at parietal sites, which was also sensitive to unpleasantness. These results imply that ERP reflecting episodic conscious recollection and post-retrieval monitoring are clearly affected both by valence and arousal.
文摘The choice of reading materials partly decides the effectiveness of classroom reading instructions in TESL.This paper analyses the cognitive process of reading and some problems in classroom reading instructions of reading course,and suggests three basic principles for choosing reading materials,including the principle of comprehensibility reading materials,readers’familiarity with the topics of the reading materials,and the sufficiency of reading materials.
文摘Emery dreifuss muscular dystrophy(EDMD) is a rare genetic syndrome consisting of tendon retractions,progressive muscle atrophy and cardiac involvement.We report a case of an obese patient affected by the familial X-linked form in which a pericallosal lipoma was found during investigation for a suspected acute vasculopathy.To date,EDMD has never been associated with cerebral lipomas and the X-linked form was never considered to be involved in lipodystrophic syndromes or non-muscular conditions.Our case confirms the variable expressivity of the disease and suggests a possible role of Emerin in the intranuclear regulation of signals for adipocyte cell differentiation.
基金the funds of "the Youth Fund of Nantong Health Bureau 2015",ID:WQ2015009
文摘Dilated cardiomyopathy(DCM)is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM concomitant with arrhythmias and sudden death resulting from gene mutation has been widely