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用(+)-FLEC手性试剂自动柱前衍生高效液相色谱法拆分麻黄碱类药物对映体 被引量:9
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作者 金晓 崔凯荣 《药学学报》 CAS CSCD 北大核心 1994年第2期122-127,共6页
报道了以(+)-FLEC作为手性衍生化试剂,用反相高效液相色谱技术分离麻黄碱类药物对映异构体的方法。dl-麻黄碱、dl-伪麻黄碱、dl-去甲麻黄碱、dl-去甲伪麻黄碱先与(+)-FLEC形成衍生物后,经过一ODSHy... 报道了以(+)-FLEC作为手性衍生化试剂,用反相高效液相色谱技术分离麻黄碱类药物对映异构体的方法。dl-麻黄碱、dl-伪麻黄碱、dl-去甲麻黄碱、dl-去甲伪麻黄碱先与(+)-FLEC形成衍生物后,经过一ODSHypersil柱分离,以水和乙腈为流动相梯度洗脱.二极管阵列检测器在266nm检测。该法从样品衍生化到最终报告全部自动完成。上述各对对映体均达到基线分离,分离度R均大于1.5,方法灵敏度高,最低检出限达10pmo1,保留时间和峰面积的上现性较好,RSD分别为1.1/和3.0%。 展开更多
关键词 衍生化试剂 麻黄碱 高效液相色谱
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Measurements of Formaldehyde and TVOC Emission from Paints and Coating Materials using Small Chamber Method for Building Composites 被引量:1
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作者 Jin-A KIM Sumin KIM +1 位作者 Hyun-Joong KIM Janghoo SEO 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2012年第1期120-125,共6页
An optimal test method for paint is proposed; additionally, the Field and Laboratory Emission Cell (FLEC) method used in Europe is applied as a substitute for the 20 L small chamber method. The emission factors of t... An optimal test method for paint is proposed; additionally, the Field and Laboratory Emission Cell (FLEC) method used in Europe is applied as a substitute for the 20 L small chamber method. The emission factors of total volatile organic compounds (TVOC) and formaldehyde from oil-based paint, emulsion paint, and water-dispersion paint with a coating weight of 300 g/m2, cured for 24/48 hours, were measured using the 20 L small chamber method. The emission rate of TVOC and formaldehyde from all paints began to stabilize after approximately 7 days after 24/48 hours of curing even though Korean standards stipulate that paint should be measured and analyzed after the third day of application. The emission factor of TVOC and formaldehyde from oil-based, emulsion, and water-dispersion paints were also measured using the FLEC method. There was good correlation between the 20 L small chamber method and the FLEC method for oil-based, emulsion, and water-dispersion paint emissions. With the FLEC method, using paints prepared under identical conditions, the emission rate was stable 24 hours after installation of samples because the air flow rate of FLEC is much higher than that of a 20 L small chamber, and the relative cell volume of FLEC is much smaller than that of a 20 L small chamber. 展开更多
关键词 FORMALDEHYDE TVOC paints coating materials flec
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