血流动力学管理是急危重症患者循环功能监测的重要组成部分。传统血流动力学监测方法有创、昂贵,并不适合急诊患者。呼气末二氧化碳分压(partial pressure of end tidal carbon dioxide,PetCO2)简便、无创、实时,不仅反映了机体基础代...血流动力学管理是急危重症患者循环功能监测的重要组成部分。传统血流动力学监测方法有创、昂贵,并不适合急诊患者。呼气末二氧化碳分压(partial pressure of end tidal carbon dioxide,PetCO2)简便、无创、实时,不仅反映了机体基础代谢情况,还反映了循环和通气情况,是血流动力学监测的新兴手段。本文主要介绍PetCO2在血流动力学管理中的应用进展,包括PetCO2生理学基础、PetCO2在休克和心肺复苏(cardiopulmonary resuscitation,CPR)中的应用、PetCO2与容量反应性(fluid responsiveness,FR)、二氧化碳容积(volumetric carbon dioxide,VCO2)与FR。展开更多
A high-order Navier-Stokes solver based on the flux reconstruction(FR)or the correction procedure via reconstruction(CPR)formulation is employed to perform a direct numerical simulation(DNS)and large eddy simulations(...A high-order Navier-Stokes solver based on the flux reconstruction(FR)or the correction procedure via reconstruction(CPR)formulation is employed to perform a direct numerical simulation(DNS)and large eddy simulations(LES)of a well-known benchmark problem–transitional flow over the low-pressure T106C turbine cascade.Hp-refinement studies are carried out to assess the resolution requirement.A 4th order(p3)simulation on the fine mesh is performed with a DNS resolution to establish a"converged"solution,including the mean pressure and skin-friction distributions,and the power spectral density in the wake.Then LES on the coarse and fine meshes with lower order schemes are conducted to assess the mesh and order dependence of the solution.In particular,we study the error in the transition location,the mean skin-friction distribution,and the mean lift and drag coefficients.These h-and p-refinement studies provide a much-needed guideline in h-and p-resolutions to achieve a certain level of accuracy for industrial LES applications.展开更多
基金AFOSR grant(FA9550-16-1-0128)US Army Research Office grant(W911NF-15-1-0505).
文摘A high-order Navier-Stokes solver based on the flux reconstruction(FR)or the correction procedure via reconstruction(CPR)formulation is employed to perform a direct numerical simulation(DNS)and large eddy simulations(LES)of a well-known benchmark problem–transitional flow over the low-pressure T106C turbine cascade.Hp-refinement studies are carried out to assess the resolution requirement.A 4th order(p3)simulation on the fine mesh is performed with a DNS resolution to establish a"converged"solution,including the mean pressure and skin-friction distributions,and the power spectral density in the wake.Then LES on the coarse and fine meshes with lower order schemes are conducted to assess the mesh and order dependence of the solution.In particular,we study the error in the transition location,the mean skin-friction distribution,and the mean lift and drag coefficients.These h-and p-refinement studies provide a much-needed guideline in h-and p-resolutions to achieve a certain level of accuracy for industrial LES applications.
