Bilateral sequential femoral neck stress fractures in young adult with HIV infection on antiretroviral therapy: A case report

BACKGROUND Femoral neck stress fractures are rarely encountered among young adults and are often associated with either repetitive excessive loading or underlying bone pathology.Preliminary research has indicated human immunodeficiency virus(HIV)/antiretroviral therapy(ART)as predisposing agents to osteopenia and osteoporosis related complications.We report a case of HIV/ART induced insufficiency fracture in a resource limited setting in Central India.Our aim is to increase awareness and promote screening of HIV/ART related osteopenia and osteoporosis in order to prevent catastrophic orthopaedic complications.CASE SUMMARY A 35-year-old HIV positive male presented with a stress fracture of left femoral neck.The patient was on ART and reported no comorbidities.He went on to be successfully managed surgically.However,during work-up osteopenia of the contralateral proximal femur was recognised using Singh’s Index.Six months post-op the patient presented with right-sided femoral-neck stress fracture.At this stage the patient was nonconcordant with ART and denied surgical fixation.CONCLUSION In the absence of co-morbidities,several mechanisms of HIV/antiretroviral therapy may have played a role in predisposing our patient towards such a presentation.We recommend routine screening all HIV-infected patients for osteopenia,especially in younger individuals.In low resource settings and district hospitals,pelvis radiograph&Singh’s index can be used for screening.

Teriparatide anabolic therapy as potential treatment of type Ⅱ dens non-union fractures

Odontoid fractures account for 5% to 15% of all cervical spine injuries and 1% to 2% of all spine fractures. Type Ⅱ fractures are the most common fracture pattern in elderly patients. Treatment(rigid and non-rigid immobilization, anterior screw fixation of the odontoid and posterior C1-C2 fusion) remains controversial and represents a unique challenge for the treating surgeon. The aims of treatment in the elderly is to quickly restore pre-injury function while decreasing morbidity and mortality associated with inactivity, immobilization with rigid collar and prolonged hospitalization. Conservative treatment of type Ⅱ odontoid fractures is associated with relatively high rates of non-union and in a few cases delayed instability. Options for treatment of symptomatic non-unions include surgical fixation or prolonged rigid immobilization. In this report we present the case of a 73-year-old woman with post-traumatic odontoid nonunion successfully treated with Teriparatide systemic anabolic therapy. Complete fusion and resolution of the symptoms was achieved 12 wk after the onset of the treatment. Several animal and clinical studies have confirmed the potential role of Teriparatide in enhancing fracture healing. Our case suggests that Teriparatide may have a role in improving fusion rates of C2 fractures in elderly patients.

Effect of mid-frequency pulse therapy combined with external fixation on bone metabolism, inflammatory response and oxidative stress in patients with osteoporotic distal radial fractures

Objective:To study the effect of mid-frequency pulse therapy combined with external fixation on bone metabolism, inflammatory response and oxidative stress in patients with osteoporotic distal radial fractures.Methods: A total of 72 patients with osteoporotic distal radial fractures who were treated in the hospital between September 2015 and January 2017 were collected and divided into control group (n=36) and observation group (n=36) according to the random number table method. Control group received routine external fixation, and observation group received mid-frequency pulse therapy combined with external fixation. The differences in serum levels of bone metabolism indexes, inflammatory factors and oxidative stress indexes were compared between two groups of patients before and after treatment.Results: Before treatment, differences in serum levels of bone metabolism indexes, inflammatory factors and oxidative stress indexes were not statistically significant between the two groups. After 1 month of treatment, serum BGP, TAC and SOD levels of both groups of patients were higher than those before treatment whileβ-CTX, AKP, TRAP, CRP, IL-1β, IL-6 and MDA levels were lower than those before treatment, and serum BGP, TAC and SOD levels of observation group were higher than those of control group whileβ-CTX, AKP, TRAP, CRP, IL-1β, IL-6 and MDA levels were lower than those of control group.Conclusion: Mid-frequency pulse therapy combined with external fixation can promote fracture healing and reduce postoperative inflammatory response and oxidative stress response in patients with osteoporotic distal radial fracture.

Osteoporosis and fractures in liver disease: Relevance, pathogenesis and therapeutic implications

It is being increasingly recognized that patients with liver disease develop bone loss that can be severe enough to lead to atraumatic fractures and thus markedly diminish life quality and expectancy. The estimated prevalence for liver-related osteoporosis is between 20-420/100000 of the general population, and fractures between 60-880/100000. It should be kept in mind that up to 40% of patients with chronic liver disease may experience a fracture. The pathogenic mediators include fibronectin, insulin like growth factor-I, and various cytokines, but decreased vitamin D and/or treatment with corticosteroids contribute to worsening bone health. Despite the advances in bone biology that have shed some light on the pathogenesis of this bone loss, treatment options remain nonspecific and tightly linked to treatments of other forms of osteoporosis. Thus, treatment should include calcium and vitamin D supplementation in all patients with chronic liver disease. Therapy with bisphosphonates should be considered, especially in patients receiving corticosteroids. This review focuses on the prevalence of this entity as well as the evidence available with regard to the pathogenesis of bone loss in liver disease, the diagnostic steps required in all patients, and the therapeutic options available.

Low-velocity simultaneous bilateral femoral neck fracture following long-term antiepileptic therapy:A case report

BACKGROUND Simultaneous bilateral femoral neck fractures are relatively rare injuries.They are usually associated with underlying metabolic bone disorders or systemic diseases.Long-term use of narcotics and bisphosphonates can also result in similar fracture patterns;however,association of this fracture type with longterm use of antiepileptic drugs is not very common.Only one such case has been reported in the literature.This article describes the second.CASE REPORT We report a case of simultaneous displaced bilateral femoral neck fractures in a 50-year-old epileptic patient,who had taken phenytoin for the past 3 years.The fractures were a result of low-velocity injury following a fall from the bed.The fractures were managed with a bilateral hemi-replacement arthroplasty.Oral bisphosphonates were given to improve the bone quality in the post-operative period.The patient had a good post-operative outcome,that was sustained throughout the entire follow-up period of 1 year.CONCLUSION Antiepileptic drugs should be supplemented with bisphosphonates and vitamin D to improve bone quality and prevent fractures in epileptic patients.

Intramedullary nailing for pathological fractures of the proximal humerus caused by multiple myeloma: A case report and review of literature

BACKGROUND Multiple myeloma(MM)bone disease is indicative of MM,and reduces patient life quality.In addition to oncological,antineoplastic systemic therapy,surgical therapy in patients with MM is an essential treatment within the framework of supportive therapy measures and involves orthopedic tumor surgery.Nevertheless,there are few reports on intramedullary(IM)nailing in the treatment of MM-induced proximal humeral fracture to prevent fixation loss.We here describe a case of pathological fracture of the proximal humerus caused by MM successfully treated with IM nailing without removal of tumors and a review of the current literature.CASE SUMMARY A 64-year-old male patient complaining of serious left shoulder pain and limited movement was admitted.The patient was finally diagnosed with MM(IgAλ,IIIA/II).After treatment of the pathological fracture with IM nailing,the patient's function recovered and his pain was rapidly relieved.Histopathological examination demonstrated plasma cell myeloma.The patient received chemotherapy in the Hematology Department.The humeral fracture displayed good union during the 40-mo follow-up,with complete healing of the fracture,and the clinical outcome was satisfactory.At the most recent follow-up,the patient's function was assessed using the Musculoskeletal Tumor Society score,which was 29.CONCLUSION Early surgery should be performed for the fracture of the proximal humerus caused by MM.IM nailing can be used without removal of tumors.Bone cement augmentation for bone defects and local adjuvant therapy can also be employed.

IRRIGATION AND TRACTION THERAPY FOR OPEN FRACTURE WITH LARGE－SIZED FULL－THICKNESS SKIN－DEFICIT AND SEVERELY INFECTED WOUND

In this paper the results of skeletal traction and irrigation therapy (STIT) used for open fracture complicated with large-sized full-thickness skin-deficit and infection wounds (OFIW) were presented. Fourteen patients of OFIW were treated by the plaster cast and wound dressing (PCWD), and 30 patients of OFIW were treated by STIT. The results indicated that after one week of treatment, the white blood cell count in the STIT group, compared to 17. 6±l. 0×109/L from before treatment, returned to 8. 8±0. 8×109/L,and in contrast, the cell count of the PCWD group was about 13. 0±1. 4×109/L. All of wound exudate culture in the STIT group was negative, and those of 7 cases (7/14) in PCWD group were positive (P<0. 0l). The symptoms and signs such as pain, fever and septic exudate on the wound in the STIT group were much milder than those in the PCWD group. There were 5 cases (35. 7%) of toxicemia and septicemia, 2 cases (14. 3%) of osteomyelitis, 2 cases (14. 3 %) of amputation, 1 case (7. 1%) of delayed union and 3 cases (21. 4 %) of malunion in the PCWD group, and no complications in the STIT group.

Preventing Lower Extremity Deep Vein Thrombosis After Hip Fracture Surgery in Elderly Patients by Acupoint Application Combined with Pneumatic Compression Therapy

Objective:To investigate and analyze the long-term clinical effects of acupoint application combined with pneumatic compression therapy in the prevention of deep venous thrombosis after hip fracture surgery among the elderly.Methods:Sixty elderly patients who had undergone hip fracture surgery from February 2021 to February 2022 were selected as the research subjects.The patients were divided into two groups via drawing lots.Both the groups received nursing care,but the patients in the observation group were treated with TCM acupoint application combined with pneumatic compression therapy,whereas the control group received pneumatic compression therapy.The evaluation indicators included the patients’quality of life and complications.Results:The incidence of lower extremity deep vein thrombosis in the observation group was more than twice(0.3%),whereas the incidence of lower extremity complications in the control group was more than 6 times(20%).There was a significant difference between the two groups(p<0.05).Conclusion:Traditional Chinese medicine acupoint application combined with pneumatic compression therapy is beneficial for the prevention of postoperative lower extremity deep vein thrombosis among elderly patients.In addition,the patients’overall quality-of-life scores in both physiological and psychological aspects improved significantly,which carries significant clinical reference value.

Investigation of Therapeutic Effect of Traditional Mongolian Osteopathy Manual Reduction with Medicinal Wine Spraying Massage and Small Splint External Fixation Therapy for Treatment of Neerll-type Distal Humerus Fracture

Objectives:To investigate the effect of traditional Mongolian osteopathy manual reduction with medicinal wine spraying massage and small splint external fixation therapy for treatment of Neerll-type distal humerus fractures.Methods:Sample selection was carried out during time period from November 2014 to May 2019.Sixty-six patients admitted to our hospital were selected as sample patients.The control group was given plaster treatment,while the observation group was given traditional Mongolian osteopathy manual reduction with medicinal wine spraying massage and small splint external fixation therapy.Efficacy for the two groups of patients was observed.Results:In this study,the total effective rate of observation group patients with treatment of traditional Mongolian osteopathy manual reduction with medicinal wine spraying massage and small splint external fixation therapy was 100%.Meanwhile,total effective rate of patients in control group was 87.88%.The difference was significant,P<0.05.Conclusions:In this study of clinical treatment,traditional Mongolian osteopathy manual reduction with medicinal wine spraying massage and small splint external fixation therapy could provide better therapeutic effect for treatment of patients with Neerll-type distal humerus fracture.At the same time,it reduces economic burden of patients.It has higher promotion value for clinical practice.

Comparison of locomotion therapy between pelvis traction therapy to treat fracture of thoracolumber

Compare the effects of locomotion therapy and pelvis traction therapy to treat Ⅰ～Ⅱ° thoracolumbar compression fracture.Methods Ninety-two cases with Ⅰ～Ⅱ° thoracolumbar compression fracture were selected and divided into 2 groups with locomotion therapy and pelvis traction thepapy respectively.Results Thoracolumbar height was measured according to X-ray results after 1 year follow-up.The height was (17.2±2.3)mm preoperatively and (24.4±3.1)mm postoperatively in locomotion therapy group while (16.8±2.6)mm preoperatively and (23.9±2.7)mm postoperatively in the pelvis traction therapy group.Conclusion There is no significant difference between effects on two groups.5 refs.

Recent biological trends in management of fracture non-union

Bone regeneration is a complex, well-orchestrated physiological process of bone formation, which can be seen during normal fracture healing, and is involved in continuous remodelling throughout adult life. Currently,there is a plethora of different strategies to augment the impaired or "insufficient" bone-regeneration process, including the "gold standard" autologous bone graft, free fibula vascularised graft, allograft implantation, and use of growth factors, osteoconductive scaffolds, osteoprogenitor cells and distraction osteogenesis. Improved "local" strategies in terms of tissue engineering and gene therapy, or even "systemic" enhancement of bone repair, are under intense investigation, in an effort to overcome the limitations of the current methods, to produce bone-graft substitutes with biomechanical properties that are as identical to normal bone as possible, to accelerate the overall regeneration process, or even to address systemic conditions, such as skeletal disorders and osteoporosis. An improved understanding of the molecular and cellular events that occur during bone repair and remodeling has led to the development of biologic agents that can augment the biological microenvironment and enhance bone repair. Orthobiologics, including stem cells, osteoinductive growth factors, osteoconductive matrices, and anabolic agents, are available clinically for accelerating fracture repair and treatment of compromised bone repair situations like delayed unions and nonunions. A lack of standardized outcome measures for comparison of biologic agents in clinical fracture repair trials, frequent off-label use, and a limited understanding of the biological activity of these agents at the bone repair site have limited their efficacy in clinical applications.

Osteoporotic fracture and parathyroid hormone

Osteoporosis and age-related bone loss is associated with changes in bone remodeling characterized by decreased bone formation relative to bone resorption,resulting in bone fragility and increased risk of fractures.Stimulating the function of bone-forming osteoblasts,is the preferred pharmacological intervention for osteoporosis.Recombinant parathyroid hormone(PTH),PTH(1-34),is an anabolic agent with proven benefits to bone strength and has been characterized as a potential therapy for skeletal repair.In spite of PTH’s clinical use,safety is a major consideration for long-term treatment.Studies have demonstrated that intermittent PTH treatment enhances and accelerates the skeletal repair process via a number of mechanisms.Recent research into the molecular mechanism of PTH action on bone tissue has led to the development of PTH analogs to control osteoporotic fractures.This review summarizes a number of advances made in the field of PTH and bone fracture to combat these injuries in humans and in animal models.The ultimate goal of providing an alternative to PTH,currently the sole anabolic therapy in clinical use,to promote bone formation and improve bone strength in the aging population is yet to be achieved.

Critical review of bone health,fracture risk and management of bone fragility in diabetes mellitus

The risk of fracture is increased in both type 1 diabetes mellitus(T1DM)and type 2 diabetes mellitus(T2DM).However,in contrast to the former,patients with T2DM usually possess higher bone mineral density.Thus,there is a considerable difference in the pathophysiological basis of poor bone health between the two types of diabetes.Impaired bone strength due to poor bone microarchitecture and low bone turnover along with increased risk of fall are among the major factors behind elevated fracture risk.Moreover,some antidiabetic medications further enhance the fragility of the bone.On the other hand,antiosteoporosis medications can affect the glucose homeostasis in these patients.It is also difficult to predict the fracture risk in these patients because conventional tools such as bone mineral density and Fracture Risk Assessment Tool score assessment can underestimate the risk.Evidence-based recommendations for risk evaluation and management of poor bone health in diabetes are sparse in the literature.With the advancement in imaging technology,newer modalities are available to evaluate the bone quality and risk assessment in patients with diabetes.The purpose of this review is to explore the patho-physiology behind poor bone health in diabetic patients.Approach to the fracture risk evaluation in both T1DM and T2DM as well as the pragmatic use and efficacy of the available treatment options have been discussed in depth.

Treatment for subtrochanteric fracture and subsequent nonunion in an adult patient with osteopetrosis:A case report and review of the literature

BACKGROUND As a congenital metabolic bone disease caused by defective osteoclastic resorption of immature bone,osteopetrosis is characterized by diffused sclerosis of bones,brittle bones,easy fracturing,narrow medullary canals,and a weak fracture healing ability.At present,clear standards and principles for the treatment of fractures in patients with osteopetrosis are lacking.Non-operative treatment can prevent fracture hematoma and preserve the blood supply to the bone fragments,while being associated with frequent failures and higher mortality rates.Meanwhile,closed reduction and internal fixation with intramedullary nail(CRIF+IMN)approaches can also protect blood supply to the fracture site.However,IMN cannot be used for the vast majority of patients with osteopetrosis due to the narrowing of medullary canals.Thus,open reduction and internal fixation with plate remains the most appropriate surgical method for treating fractures in patients with osteopetrosis,but this approach is complicated by the lack of intramedullary hematopoiesis in such patients.Fracture healing primarily depends on the blood supply to the external periosteum.Open reduction can also easily destroy the periosteum and cause delayed fracture healing or even nonunion;however,CRIF may be the most practical approach.As a result,it would be prudent to solve the difficulty of drilling during the operation and the problem of postoperative nonunion.CASE SUMMARY In 2018,we treated an adult patient with osteopetrosis presenting with a subtrochanteric fracture.The fracture was fixed using a femoral locking compression plate.Because of delayed consolidation,at 12 mo postoperatively the patient was further treated with platelet-rich plasma(PRP)combined with radial extracorporeal shock wave therapy(rESWT).Antero-posterior and lateral radiographs obtained at the latest follow-up(10 mo)showed that the callus had grown at the original fracture site,and the medial fracture line almost disappeared.CONCLUSION Osteosynthesis remains the first choice of treatment approach for fractures in patients with osteopetrosis,especially peritrochanteric fractures.Preoperative preparation is necessary to avoid risks such as drill bit breakage and iatrogenic fracture during the operation.Moreover,fractures in a patient with osteopetrosis present with a high risk of delayed union and nonunion,which can be potentially cured with PRP+rESWT.

Effects of different root canal preparation methods on root fracture resistance:A systematic review of the literature

AIM: To study the root fracture resistance after root canal preparation with Ni-Ti rotary instruments and stainless hand instruments by means of meta-analysis.METHODS: Literature was researched in CNKI and CBMDisc, Pub Med, CALIS, Proquest, Web of Scienceand 11 kinds of Chinese or English dentistry journals. Retrieval time on Internet was in all years and hand retrieval time was from January 2013 to October 2013. The literatures were selected through reading abstracts and full texts by two reviewers independently and Revman 5 software was used to analysize the literature. RESULTS: Six articles met the inclusion criteria. According to Meta-analysis of tooth root bending properties, total standardized mean difference(SMD) was 0.63(95%CI:-0.24-1.50, P > 0.05). That indicated there was no statistically significant between the two groups. Subgroup analysis was carried out. SMD were 2.22(95%CI: 0.23-4.20, P < 0.05) and-0.61(95%CI:-1.05--0.17, P < 0.05) when the premolar teeth with a single canal or the mesiobuccal roots of molars were used as the materials for tests to compare the effects of different root canal preparation methods on root fracture resistance. That only indicated that there were statistically significant in two subgroups.CONCLUSION: In vitro experiments, the effects on the fracture resistance of root had no statistical difference with Ni-Ti rotary instruments and stainless steel hand instruments in root canal preparation.

针刺联合补肾活血方治疗骨质疏松性胸腰椎骨折的疗效观察及对骨代谢水平的影响

目的观察针刺联合补肾活血方治疗骨质疏松性胸腰椎压缩性骨折的临床疗效及对患者血清骨代谢指标的影响。方法选择108例骨质疏松性胸腰椎骨折患者,随机分为对照组和联合组,每组54例。两组均进行椎体后凸成形术治疗和常规护理,对照组口服补肾活血方治疗,联合组采用针刺联合口服补肾活血方治疗。比较两组疼痛缓解时间、下床活动时间和骨折愈合时间,观察两组治疗前和随访结束时疼痛数字评估表(numerical rating scale,NRS)评分、中国人骨质疏松症简明生存质量量表(Chinese osteoporosis quality of life short questionnaire,COQOL)评分和Oswestry功能障碍指数(Oswestry disability index,ODI)的变化,观察两组治疗前和随访结束时骨折椎体的椎形态及骨密度检测结果的变化,观察治疗前后两组血清高迁移率族蛋白-1(high mobility group protein-1,HMGB-1)、C-反应蛋白(C-reactive protein,CRP)、P物质(substance P,SP)、皮质醇(cortisol,Cor)、骨形态发生蛋白-7(bone morphogenetic protein-7,BMP-7)、骨钙素N端中分子片段(osteocalcin n-terminal molecular fragment,N-MID)、网膜素-1(omentin-1)、Ⅰ型胶原C端肽(typeⅠcollagen C-terminal peptide,CTX-1)水平的变化,比较两组临床疗效。结果联合组疼痛缓解时间、下床活动时间和骨折愈合时间短于对照组(P<0.05),联合组治疗后HMGB-1、CRP、SP、Corh和CTX-1水平以及随访结束时伤椎楔变角、Cobb角、ODI评分、NRS评分和COQOL评分均低于对照组(P<0.05),联合组治疗后N-MID、Omentin-1和BMP-7水平以及随访结束时骨折椎体椎前缘高度和BMD水平高于对照组(P<0.05)。联合组总有效率高于对照组(P<0.05)。结论在椎体后凸成形术治疗和常规护理基础上,针刺联合补肾活血方治疗骨质疏松性胸腰椎骨折可减少炎症反应和应激反应,降低疼痛介质指标水平,改善骨性标志物及骨代谢水平,促进椎体愈合,提高腰椎功能、临床疗效及生活质量。

低频脉冲电疗配合无痛运动疗法在PVP治疗OVCF中的应用

目的:探究低频脉冲电疗配合无痛运动疗法在经皮椎体成形术(PVP)治疗骨质疏松性椎体压缩骨折(OVCF)患者中的应用价值。方法:收集在医院骨科接受PVP治疗的70例OVCF患者,据随机信封法划分为观察组(35例)与对照组(35例)。对照组患者实施常规围术期康复干预方案,观察组患者基于对照组常规干预方案上实施低频脉冲电疗配合无痛运动疗法。持续干预4周,比较两组干预后腰椎活动度,干预前后疼痛NRS评分、腰椎功能ODI评分、日常生活活动能力ADL评分、生活质量评分;比较两组干预总体优良率。结果:干预后,观察组患者左右弯曲、前屈及后伸、左右旋转的腰椎活动度均高于对照组(P<0.05),两组患者NRS评分及ODI评分均较治疗前降低,但观察组降低幅度大于对照组(P<0.05);两组患者ADL评分及生活质量评分均较治疗前升高,但观察组改善幅度大于对照组(P<0.05);观察组患者干预总体优良率明显高于对照组(P<0.05)。结论:骨质疏松压缩骨折患者在PVP治疗的术后采用低频脉冲电疗配合无痛运动疗法进行康复干预的效果显著,且能明显减轻腰椎疼痛感,改善腰椎功能,提升日常生活活动能力,辅助改善患者预后生活质量,值得推广。

关节镜双后内入路手术结合早期运动康复与物理治疗对后交叉韧带胫骨止点撕脱骨折膝关节功能的影响

目的探究关节镜双后内入路手术结合早期运动康复与物理治疗对后交叉韧带胫骨止点撕脱骨折膝关节功能的影响。方法前瞻性选取2020年4月至2022年4月在秦皇岛市第一医院接受关节镜双后内入路手术的后交叉韧带胫骨止点撕脱骨折患者90例,按照信封法将其分为研究组与对照组,每组各45例。在常规治疗的基础上,对照组接受物理治疗,研究组接受早期运动康复治疗。随访6个月,对两组患者术后疗效、下肢功能恢复情况(下床行走时间、住院时间、骨折愈合时间、术后下肢负重时间)、膝关节活动范围[屈曲角度、伸直受限角度及关节活动范围]、美国特种外科医院膝关节评分(HSS)量表(疼痛、功能、活动度、肌力、屈曲畸形及稳定性HSS)、患者满意度进行记录,并分析组间差异。结果研究组患者的治疗有效率为91.11%,高于对照组(75.56%),差异有统计学意义(P<0.05)。研究组患者下床行走时间、住院时间、骨折愈合时间、术后下肢负重时间均短于对照组,差异均有统计学意义(P<0.05)。治疗后6个月,两组患者的屈曲角度、关节活动范围均较治疗前增大,伸直受限角度均较治疗前减小,研究组屈曲角度、关节活动范围分别为(112.55±5.16)°、(108.66±11.02)°,均大于对照组[(97.89±4.51)°、(95.16±12.04)°],研究组伸直受限角度为(3.35±1.08)°,小于对照组[(4.89±1.62)°],差异均有统计学意义(P<0.05);治疗后6个月,两组患者在疼痛、功能、活动度、肌力、屈曲畸形及稳定性等方面的评分均较治疗前升高,且研究组在各方面的评分均高于对照组,差异均有统计学意义(P<0.05)。研究组患者的满意率为95.56%,高于对照组(80.00%),差异有统计学意义(P<0.05)。结论关节镜双后内入路手术结合早期运动康复对后交叉韧带胫骨止点撕脱骨折的治疗效果较好,可以明显改善患者的症状、促进愈合、提高膝关节功能,同时提高患者的满意度。

红光治疗仪联合藻酸盐敷料对下肢骨折术后创面愈合的疗效

目的:探讨红光治疗仪联合藻酸盐敷料对下肢骨折术后创面愈合效果。方法:选取80例下肢骨折患者,分为观察组与对照组,比较两组治疗前后FN与EGF水平差异。结果:观察组在术后14d、21d、28d的骨痂密度评分均高于对照组(P<0.05)。观察组术后2d、4d、6d疼痛评分均低于对照组(P<0.05)。治疗后,两组血清FN和EGF水平均高于治疗前,且观察组血清FN和EGF水平高于对照组(P<0.05)。结论:红光治疗仪联合藻酸盐敷料用于下肢骨折术后创面愈合,安全有效,能够促进骨痂生长,减轻患者疼痛程度,改善血清FN与EGF水平。

改良冰肌散联合气压疗法预防股骨骨折下肢深静脉血栓临床观察

目的探究改良冰肌散联合气压疗法预防股骨骨折下肢深静脉血栓(LDVT)的临床疗效。方法采用回顾性观察性研究,选取2019年1月—2020年6月江西中医药大学附属医院骨科收治的股骨骨折患者60例。其中对照组30例行冰肌散涂药治疗,研究组30例行冰肌散涂药联合气压治疗。比较两组患者LDVT的发生率、疼痛视觉模拟量表(VAS)评分、下肢肿胀的变化及不良反应发生率。结果与对照组比较,研究组患者LDVT的发生率、下肢肿胀发生率及VAS评分均显著降低(P<0.05)。研究组治疗总有效率为93.33%(28/30),高于对照组的80.00%(24/30)(P<0.05)。两组患者治疗期间均未出现不良反应。结论改良冰肌散联合气压疗法预防股骨骨折LDVT的临床显著。