To describe the empirical data of collaboration networks, several evolving mechanisms have been proposed, which usually introduce different dynamics factors controlling the network growth. These models can reasonably ...To describe the empirical data of collaboration networks, several evolving mechanisms have been proposed, which usually introduce different dynamics factors controlling the network growth. These models can reasonably reproduce the empirical degree distributions for a number of we11-studied real-world collaboration networks. On the basis of the previous studies, in this work we propose a collaboration network model in which the network growth is simultaneously controlled by three factors, including partial preferential attachment, partial random attachment and network growth speed. By using a rate equation method, we obtain an analytical formula for the act degree distribution. We discuss the dependence of the act degree distribution on these different dynamics factors. By fitting to the empirical data of two typical collaboration networks, we can extract the respective contributions of these dynamics factors to the evolution of each networks.展开更多
Collaborative f iltering, as one of the most popular techniques, plays an important role in recommendation systems. However,when the user-item rating matrix is sparse,its performance will be degenerate. Recently,domai...Collaborative f iltering, as one of the most popular techniques, plays an important role in recommendation systems. However,when the user-item rating matrix is sparse,its performance will be degenerate. Recently,domain-specific recommendation approaches have been developed to address this problem.The basic idea is to partition the users and items into overlapping domains, and then perform recommendation in each domain independently. Here, a domain means a group of users having similar preference to a group of products. However, these domain-specific methods consisting of two sequential steps ignore the mutual benefi t of domain segmentation and recommendation. Hence, a unified framework is presented to simultaneously realize recommendation and make use of the domain information underlying the rating matrix in this paper. Based on matrix factorization,the proposed model learns both user preferences of multiple domains and preference selection vectors to select relevant features for each group of products. Besides, local context information is utilized from the user-item rating matrix to enhance the new framework.Experimental results on two widely used datasets, e.g., Ciao and Epinions, demonstrate the effectiveness of our proposed model.展开更多
Identifying the potential drug-target interactions(DTI)is critical in drug discovery.The drug-target interaction prediction methods based on collaborative filtering have demonstrated attractive prediction performance....Identifying the potential drug-target interactions(DTI)is critical in drug discovery.The drug-target interaction prediction methods based on collaborative filtering have demonstrated attractive prediction performance.However,many corresponding models cannot accurately express the relationship between similarity features and DTI features.In order to rationally represent the correlation,we propose a novel matrix factorization method,so-called collaborative matrix factorization with soft regularization(SRCMF).SRCMF improves the prediction performance by combining the drug and the target similarity information with matrix factorization.In contrast to general collaborative matrix factorization,the fundamental idea of SRCMF is to make the similarity features and the potential features of DTI approximate,not identical.Specifically,SRCMF obtains low-rank feature representations of drug similarity and target similarity,and then uses a soft regularization term to constrain the approximation between drug(target)similarity features and drug(target)potential features of DTI.To comprehensively evaluate the prediction performance of SRCMF,we conduct cross-validation experiments under three different settings.In terms of the area under the precision-recall curve(AUPR),SRCMF achieves better prediction results than six state-of-the-art methods.Besides,under different noise levels of similarity data,the prediction performance of SRCMF is much better than that of collaborative matrix factorization.In conclusion,SRCMF is robust leading to performance improvement in drug-target interaction prediction.展开更多
基金Supported by the National Natural Science Foundation of China under Grant Nos 11305139 and 11147178
文摘To describe the empirical data of collaboration networks, several evolving mechanisms have been proposed, which usually introduce different dynamics factors controlling the network growth. These models can reasonably reproduce the empirical degree distributions for a number of we11-studied real-world collaboration networks. On the basis of the previous studies, in this work we propose a collaboration network model in which the network growth is simultaneously controlled by three factors, including partial preferential attachment, partial random attachment and network growth speed. By using a rate equation method, we obtain an analytical formula for the act degree distribution. We discuss the dependence of the act degree distribution on these different dynamics factors. By fitting to the empirical data of two typical collaboration networks, we can extract the respective contributions of these dynamics factors to the evolution of each networks.
基金supported in part by the Humanity&Social Science general project of Ministry of Education under Grants No.14YJAZH046National Science Foundation of China under Grants No.61402304the Beijing Educational Committee Science and Technology Development Planned under Grants No.KM201610028015
文摘Collaborative f iltering, as one of the most popular techniques, plays an important role in recommendation systems. However,when the user-item rating matrix is sparse,its performance will be degenerate. Recently,domain-specific recommendation approaches have been developed to address this problem.The basic idea is to partition the users and items into overlapping domains, and then perform recommendation in each domain independently. Here, a domain means a group of users having similar preference to a group of products. However, these domain-specific methods consisting of two sequential steps ignore the mutual benefi t of domain segmentation and recommendation. Hence, a unified framework is presented to simultaneously realize recommendation and make use of the domain information underlying the rating matrix in this paper. Based on matrix factorization,the proposed model learns both user preferences of multiple domains and preference selection vectors to select relevant features for each group of products. Besides, local context information is utilized from the user-item rating matrix to enhance the new framework.Experimental results on two widely used datasets, e.g., Ciao and Epinions, demonstrate the effectiveness of our proposed model.
基金This work was supported by the National Natural Science Foundation of China under Grant No.61972423Hunan Provincial Science and Technology Program under Grant No.2018wk4001.
文摘Identifying the potential drug-target interactions(DTI)is critical in drug discovery.The drug-target interaction prediction methods based on collaborative filtering have demonstrated attractive prediction performance.However,many corresponding models cannot accurately express the relationship between similarity features and DTI features.In order to rationally represent the correlation,we propose a novel matrix factorization method,so-called collaborative matrix factorization with soft regularization(SRCMF).SRCMF improves the prediction performance by combining the drug and the target similarity information with matrix factorization.In contrast to general collaborative matrix factorization,the fundamental idea of SRCMF is to make the similarity features and the potential features of DTI approximate,not identical.Specifically,SRCMF obtains low-rank feature representations of drug similarity and target similarity,and then uses a soft regularization term to constrain the approximation between drug(target)similarity features and drug(target)potential features of DTI.To comprehensively evaluate the prediction performance of SRCMF,we conduct cross-validation experiments under three different settings.In terms of the area under the precision-recall curve(AUPR),SRCMF achieves better prediction results than six state-of-the-art methods.Besides,under different noise levels of similarity data,the prediction performance of SRCMF is much better than that of collaborative matrix factorization.In conclusion,SRCMF is robust leading to performance improvement in drug-target interaction prediction.