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Therapeutic Communication Methods Targeting Families and Family Members: A Literature Review
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作者 Taketo Watsuji Naohiro Hohashi 《Open Journal of Nursing》 2024年第1期11-26,共16页
Background and Purpose: Therapeutic communication is a new term in family health care nursing, defined by Hohashi (2019) as a method of family intervention, and characterized by inclusion of not only verbal conversati... Background and Purpose: Therapeutic communication is a new term in family health care nursing, defined by Hohashi (2019) as a method of family intervention, and characterized by inclusion of not only verbal conversation but also nonverbal interaction. However, specific therapeutic communication methods have not been systematized. The purpose of this study was to clarify therapeutic communication methods for families/family members from the perspectives of verbal communication and non-verbal communication through a review of existing literature. Methods: We conducted a search using the medical literature databases PubMed and Ichushi-Web using the keywords “therapeutic communication”. Analysis was performed on seven articles from PubMed and 14 articles from Ichushi-Web that described therapeutic communication methods performed by healthcare professionals for families/family members. Through directed content analysis, therapeutic communication methods were subcategorized, and classified into three categories: verbal communication, non-verbal communication, and verbal/non-verbal communication. Results: A total of 23 subcategories were extracted. Verbal communication included 11 subcategories, such as “asking questions using the communicatee’s words as they are”. Non-verbal communication included five subcategories, such as “noticing changes in the content of the communicatee’s story”. And verbal/non-verbal communication featured seven subcategories, such as “making the communicatee aware of one’s own beliefs”. Conclusion: Therapeutic communication methods included basic care/caring in family interviews/meetings, as well as verbal communication and non-verbal communication that act on family/family members’ beliefs. It is believed that changes in family/family members’ beliefs can be used to eliminate, reduce, or improve problematic conditions in the family. . 展开更多
关键词 Therapeutic Communication Family Nursing Family Interview/Meeting Family Belief Systems Theory Literature Review
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Literature Review on Support for Children and Families Experiencing Parental Bereavement
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作者 Rurie Namiki Keita Sasaki +1 位作者 Iku Taniguchi Rie Wakimizu 《Open Journal of Nursing》 2024年第4期139-163,共25页
Purpose: This study aimed to understand the actual nursing support in a wide perspective by reviewing overseas literature on support for children who have experienced parental bereavement and their families. The goal ... Purpose: This study aimed to understand the actual nursing support in a wide perspective by reviewing overseas literature on support for children who have experienced parental bereavement and their families. The goal was to identify future challenges in nursing support in clinical practice in Japan. Method: Literature searchable as of May 2023 was retrieved using PubMed, resulting in 11 relevant articles. Result: The results revealed the following: 1) For support provided to children, 13 codes were condensed into 5 subcategories and 4 categories. 2) For support provided to families, 36 codes were condensed into 11 subcategories and 4 categories. Conclusion: Open communication was found to be essential for supporting children and their families who have experienced parental bereavement. Moreover, involvement of multiple professions facilitated the provision of specialized support to address diverse needs of children and families, playing a crucial role in overcoming grief. Additionally, the effectiveness of support systems for bereaved families highlighted the need for nursing professionals in Japan to gain knowledge through learning opportunities and to establish a multi-disciplinary approach to support, thus indicating future challenges in nursing support. 展开更多
关键词 Terminal Care Family Support CHILD Parental Death Palliative Care
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Relations Between School and Immigrant Families in Albertan Francophone School: Perspectives of Settlement Workers in Schools - A Secondary Publication
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作者 Marianne Jacquet Gwenaëlle André 《Journal of Contemporary Educational Research》 2024年第3期136-147,共12页
In recent years,Francophone schools in Alberta,a province in western Canada,have seen significant ethnocultural diversification of their school population,thus reflecting recent migratory changes in Canada.The populat... In recent years,Francophone schools in Alberta,a province in western Canada,have seen significant ethnocultural diversification of their school population,thus reflecting recent migratory changes in Canada.The population of a Francophone school board located in an agglomeration of Alberta reflects these new migratory trends.A partial ethnodemographic portrait carried out in 2003 in six of its schools indicates that 50%of the pupils come from an immigrant background and come from 23 different countries;mostly from sub-Saharan African countries.This demographic reality,confirmed more than a decade later,represents a major structural change for Francophone schools.In Alberta,as in other Canadian provinces,inclusion is at the heart of discourse and educational practices.With a transformative aim,it intends to promote ethnocultural diversity in the classroom and equal opportunities through school equity practices.This article focuses on the settlement workers in schools responsible for bridging family,community,and school cultures.The analysis of the interviews of the four workers sheds light on and questions both the institutional practices and the personal strategies put in place to face the challenges encountered in this tripartite collaboration. 展开更多
关键词 Educational inclusion and exclusion Immigration and ethnicity Interculturality and multiculturalism Family and education Help for pupils and students Actors in education Canada
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Study on the variation in and selection of Fraxinus mandshurica provenances and families in northeast China
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作者 Junfei Hao Na Chen +3 位作者 Pingyu Yan Kaiyuan Xu Lei Zhang Hanguo Zhang 《Journal of Forestry Research》 SCIE CAS CSCD 2023年第2期519-529,共11页
Fraxinus mandshurica Rupr.is one of the main afforestation species in northeast China,and there is great demand for improved F.mandshurica varieties.The results of an investigation into and analysis of the growth trai... Fraxinus mandshurica Rupr.is one of the main afforestation species in northeast China,and there is great demand for improved F.mandshurica varieties.The results of an investigation into and analysis of the growth traits of F.mandshurica provenances and families showed that there were significant differences in different periods.However,variations in growth traits decreased year by year.There was a significant negative correlation between tree heights of the provenances and sunshine hours in their areas of origin.The provenances of Xinglong,Hailin and Wuchang were selected based on the volume of 18-year-old trees.The average genetic gain from the selection of fast-growing provenances was 19.4%.Ten superior fast-growing families were selected.The average volume of the selected families was22.6%,higher than that of all families.The correlation coefficient between heights at 6-year-old and at 18a was 0.838for provenances,and between heights at 4-year-old and at 18-year-old was 0.303 for families.These results indicate that early selection for height in provenances or families could be performed at 6 years or 4 years,respectively.Early selection for DBH and volume in families could start at 8 years. 展开更多
关键词 Fraxinus mandshurica PROVENANCE Family selection Early-late correlation
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Minimal Doubly Resolving Sets of Certain Families of Toeplitz Graph
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作者 Muhammad Ahmad Fahd Jarad +1 位作者 Zohaib Zahid Imran Siddique 《Computer Modeling in Engineering & Sciences》 SCIE EI 2023年第6期2681-2696,共16页
The doubly resolving sets are a natural tool to identify where diffusion occurs in a complicated network.Many realworld phenomena,such as rumour spreading on social networks,the spread of infectious diseases,and the s... The doubly resolving sets are a natural tool to identify where diffusion occurs in a complicated network.Many realworld phenomena,such as rumour spreading on social networks,the spread of infectious diseases,and the spread of the virus on the internet,may be modelled using information diffusion in networks.It is obviously impractical to monitor every node due to cost and overhead limits because there are too many nodes in the network,some of which may be unable or unwilling to send information about their state.As a result,the source localization problem is to find the number of nodes in the network that best explains the observed diffusion.This problem can be successfully solved by using its relationship with the well-studied related minimal doubly resolving set problem,which minimizes the number of observers required for accurate detection.This paper aims to investigate the minimal doubly resolving set for certain families of Toeplitz graph Tn(1,t),for t≥2 and n≥t+2.We come to the conclusion that for Tn(1,2),the metric and double metric dimensions are equal and for Tn(1,4),the double metric dimension is exactly one more than the metric dimension.Also,the double metric dimension for Tn(1,3)is equal to the metric dimension for n=5,6,7 and one greater than the metric dimension for n≥8. 展开更多
关键词 Family of Toeplitz graph resolving sets metric dimension doubly resolving sets double metric dimension
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NORMAL CRITERION FOR FAMILIES OF HOLOMORPHIC MAPS OF SEVERAL COMPLEX VARIABLES INTO P^N(C)WITH MOVING HYPERSURFACES 被引量:1
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作者 涂振汉 曹红哲 《Acta Mathematica Scientia》 SCIE CSCD 2009年第1期169-175,共7页
This article gives a normal criterion for families of holomorphic mappings of several complex variables into P N(C)for moving hypersurfaces in pointwise general position,related to an Eremenko’s theorem.
关键词 Holomorphic mappings moving hypersurfaces normal families Picard the- orems and value distribution theory
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Genetic Variation in Growth and Cone Traits of Pinus Koraiensis Half-Sib Families in Northeast China 被引量:1
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作者 David Kombi Kaviriri Xiaoting Liu +6 位作者 Zuoyi Fan Jingyuan Wang Qi Wang Lianfu Wang Lixing Wang Damase Khasa Xiyang Zhao 《Phyton-International Journal of Experimental Botany》 SCIE 2020年第1期57-69,共13页
Genetic parameters were evaluated for growth and cone characteristics(tree height,diameter at breast height,volume,cone number,thousand seeds weight and single cone seeds weight)on 86 half-sib families of Pinus koraie... Genetic parameters were evaluated for growth and cone characteristics(tree height,diameter at breast height,volume,cone number,thousand seeds weight and single cone seeds weight)on 86 half-sib families of Pinus koraiensis aged 31 years.Analyses of variance revealed significant differences(p<0.001)in all growth and cone traits among families while no significant differences were detected among blocks and the interaction between blocks and families.The average family values for growth traits were 17.22 m,8.67 cm and 0.43 m^(3) for tree height,diameter at breast height and volume,respectively.The average cone number,thousand seeds weight and single cone seeds weight were 17.57,748.91 g and 77.25 g,respectively.Genotypic additive variance and phenotypic variances ranged from 0.00009 to 3.820 and from 0.0005 to 23.066,while genotypic and phenotypic coefficients of variation ranged from 2.693%to 37.196%and 4.963%to 60.595%,respectively.Heritability at the individual and family level ranged from 0.152 to 0.215 and 0.611 to 0.862,respectively.Growth traits were significantly positively correlated with each other,but cone traits showed a weak correlation with growth traits.Based on 10% selection rate,nine families each were selected as elite materials in terms of high performance in volume and cone numbers,with 22.16%and 43.82%genetic gain in volume and cone number,respectively.These results provide beneficial information to select excellent families and establish orchards of P.koraiensis from improved seeds. 展开更多
关键词 Pinus koraiensis half-sib families GENETIC variation selection
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The Convergence Rate of Ergodic Limits for Regularized Resolvent Families 被引量:1
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作者 张寄洲 裔永刚 《Journal of Donghua University(English Edition)》 EI CAS 2004年第6期109-114,共6页
This paper is concerned with the convergence rates of ergodic limits and approximation for regularized resolvent families for a linear Volterra integral equation. The results contain C 0-semigroups, cosine operator fu... This paper is concerned with the convergence rates of ergodic limits and approximation for regularized resolvent families for a linear Volterra integral equation. The results contain C 0-semigroups, cosine operator functions and α-times integrated resolvent family as special cases. 展开更多
关键词 REGULARIZED RESOLVENT families convergence ERGODIC limit K-functional
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Crystallography in the Spaces E<sup>2</sup>, E<sup>3</sup>, E<sup>4</sup>, E<sup>5</sup>...N<sup>0</sup>II Isomorphism Classes and Study of Five Crystal Families of Space E<sup>5</sup> 被引量:1
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作者 R. Veysseyre D. Weigel +1 位作者 T. Phan H. Veysseyre 《Advances in Pure Mathematics》 2015年第4期196-207,共12页
In the paper N0II, we describe some isomorphism classes and we apply their properties to the study of five crystal families of space E5. The names of these families are the following ones (monoclinic di iso squares)-a... In the paper N0II, we describe some isomorphism classes and we apply their properties to the study of five crystal families of space E5. The names of these families are the following ones (monoclinic di iso squares)-al, decadic-al, (monoclinic di iso hexagons)-al, (rhombotopic cosa=-1/4)-al and rhombotopic cosa=-1/5. The meaning of these names will be given in Paragraphs 5 and 6 with some geometric properties of their cell. 展开更多
关键词 CRYSTAL families of SPACE E5 NAMES Point Groups of the families Rhombotopic CRYSTAL families
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Farming Families and Climate Change Issues in Niger Delta Region of Nigeria: Extent of Impact and Adaptation Strategies 被引量:1
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作者 Michael E. Ikehi Francis M. Onu +1 位作者 Florence O. Ifeanyieze Patrick S. Paradang 《Agricultural Sciences》 2014年第12期1140-1151,共12页
The study focused on the impacts of climate change on the farmer and the farming families in Niger Delta Region of Nigeria. The study specifically evaluated the perceived resultant situations attributed to climate cha... The study focused on the impacts of climate change on the farmer and the farming families in Niger Delta Region of Nigeria. The study specifically evaluated the perceived resultant situations attributed to climate change to determine the extent of impacts of climate change on the farmer and the farming families and also explored adoptable strategies for coping with the situations. The study adopted descriptive survey research design. Two research questions and two hypotheses guided the study. The population for the study was 246,909 respondents made up of farmers and extension workers who are registered with the State Ministries of Agriculture. Out of the nine Niger Delta states, Bayelsa and Delta states were randomly chosen for the study. Proportionate stratified random sampling technique was used to select a sample size of 5,038 respondents. Structured questionnaire and interview were used to collect data. The instruments were validated by three experts. Cronbach Alpha method was used to determine the internal consistency of the questionnaire items which yielded a coefficient of 0.81. The Statistical Product and Service Solutions (SPSS v 20.0) was employed for data analysis. The statistical tools used for data analysis were weighted mean to answer research questions and standard deviation to validate the closeness of the respondents from the mean and from each other in their responses while t-test was used to test the null hypotheses. The findings of the study revealed that the extent of impacts of climate change on farmers and the farming families in Niger Delta region of Nigeria are moderate. Findings further revealed that climate change has led to increased poverty level and raised cost of production (input and labour cost) as indicated by the farmers. The study recommends that farmers in the region should be encouraged by providing incentives and subsidizing inputs for them by Federal and State governments as well as other non-governmental organizations, as this will go a long way in improving production especially as most farmers agree to continue cultivation even with the observed impacts. 展开更多
关键词 Climate Change FARMING families IMPACTS FLOODING Sea Level RISE ADAPTATION Temperature
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A Concept Analysis of Decision-Making by Families in Critical Life Situations 被引量:1
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作者 Chiyoko Kimura Ruriko Kidachi 《Open Journal of Nursing》 2019年第11期1123-1137,共15页
Background: In 2017, the elderly made up 27.3% of Japan’s population, accounting for 57.2% of all ambulance trips. When an elderly person is in a critical life situation, it is difficult to ascertain their decisions ... Background: In 2017, the elderly made up 27.3% of Japan’s population, accounting for 57.2% of all ambulance trips. When an elderly person is in a critical life situation, it is difficult to ascertain their decisions about treatment choices, and for family members who become surrogate decision-makers, this is a grave responsibility. Aim: This study aimed to shed light on the constructs that support decision-making by family members and medical staff in critical situations, and to investigate decision-making by families of the elderly in critical situations. Method: We selected 29 papers published in Japan and elsewhere that focused on families involved in treatment decisions in critical life situations and analyzed them using Rodgers’ concept analysis approach. Results: From 475 codes, we extracted six attributes, four antecedents, and four consequences. The unusual setting of the “critical care unit”, lack of time, and unstable psychological state are all considered by family members making treatment decisions, along with the patient’s prognosis, their relationship with the patient, conjecture about the patient’s wishes, and taking other family member’s views into account. Medical staff supports the family throughout the process, through provision of treatment, preparing family members to face reality, empathizing with the difficulty of decision-making, building relationships with family members, monitoring the decision-making process, and being attentive to family members’ feelings until the end. Conclusion: Our results indicate the importance of advance confirmation of patients’ wishes, and the role played by cultural context and family relations in decision-making by family members of the elderly. 展开更多
关键词 DECISION-MAKING Life CRISIS Treatment CHOICES families MEDICAL STAFF
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Analysis of Malware Families on Android Mobiles: Detection Characteristics Recognizable by Ordinary Phone Users and How to Fix It 被引量:1
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作者 Hieu Le Thanh 《Journal of Information Security》 2013年第4期213-224,共12页
The sale of products using the android Operation System (OS) phone is increasing in rate: the fact is that its price is cheaper but its configured hardware is higher, users easily buy it and the approach to this produ... The sale of products using the android Operation System (OS) phone is increasing in rate: the fact is that its price is cheaper but its configured hardware is higher, users easily buy it and the approach to this product increases the risk of the spread of mobile malware. The understanding of majority of the users of this mobile malware is still limited. While they are growing at a faster speed in the number and level of sophistication, especially their variations have created confusion for users;therefore worrying about the safety of its users is required. In this paper, the author discussed the identification and analysis of malware families on Android Mobiles. The author selected the recognizable characteristics from ordinary users with their families collected from 58 malware families and 1485 malware samples and proposed solutions as recommendations to users before installing it with the ultimate desire to mitigate the damage in the community that is on the android phone, especially the ordinary users with limited understanding about potential hazards. It would be helpful for the ordinary users to identify the mobile malware in order to mitigate the information security risk. 展开更多
关键词 Mobile Security ANDROID MALWARE families
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Effect of genetic sources on anatomical, morphological,and mechanical properties of 14-year-old genetically improved loblolly pine families from two sites in the southern United States
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作者 Charles Essien Brian K.Via +3 位作者 Gifty Acquah Thomas Gallagher Timothy McDonald Lori Eckhardt 《Journal of Forestry Research》 SCIE CAS CSCD 2018年第6期1519-1531,共13页
Tree improvement programs on loblolly pine(Pinus taeda) in the southeastern USA has focused primarily on improving growth, form, and disease tolerance.However, due to the recent reduction of design values for visually... Tree improvement programs on loblolly pine(Pinus taeda) in the southeastern USA has focused primarily on improving growth, form, and disease tolerance.However, due to the recent reduction of design values for visually graded southern yellow pine lumber(including loblolly pine), attention has been drawn to the material quality of genetically improved loblolly pine. In this study,we used the time-of-flight(TOF) acoustic tool to assess the effect of genetic families on diameter, slenderness, fiber length, microfibril angle(MFA), velocity and dynamic stiffness estimated using green density(DMOEG) and basic density(DMOEB) of 14-year-old loblolly pine stands selected from two sites. All the 184 and 204 trees of the selected eight half-sib genetic families on sites 1 and 2 respectively were tested using TOF acoustic tool, and two 5 mm core samples taken at breast height level(1.3 m)used to for the anatomical and physical properties analysis.The results indicated a significant positive linear relationship between dynamic MOEs(DMOEGand DMOEB)versus tree diameter, slenderness, and fiber length while dynamic MOEs negatively but nonsignificant correlated with MFA. While there was no significant difference in DMOEBbetween sites; velocity 2 for site 1 was significantly higher than site 2 but DMOEGwas higher for site 2 than site 1. Again, the mean DMOEGand DMOEBreported in the present study presents a snapshot of the expected static MOE for green and 12% moisture conditions respectively for loblolly pine. Furthermore, there were significant differences between families for most of the traits measured and this suggests that forest managers have the opportunity to select families that exhibit the desired fiber morphology for final product performance. Lastly,since the dynamic MOE based on green density(DMOEG),basic density(DMOEB) and velocity 2 present difference conclusions, practitioners of this type of acoustic technique should take care when extrapolating results across the sites. 展开更多
关键词 Genetic families Loblolly PINE Time-offlight Resonance-based MODULUS of ELASTICITY MODULUS of RUPTURE
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Stigma and its impact on the families of former soldiers of the German Armed Forces: An exploratory study
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作者 Katrin Schuy Simone Dors +6 位作者 Loni Brants Marie Horzetzky Gerd Willmund Andreas Strohle Peter Zimmermann Heinrich Rau Stefan Siegel 《Military Medical Research》 SCIE CAS CSCD 2019年第2期143-158,共16页
Background: Military families who have a family member with a mental illness see themselves confronted with many demands. Stigmatization is one of these challenges. Stigmatization affects not only the individual who s... Background: Military families who have a family member with a mental illness see themselves confronted with many demands. Stigmatization is one of these challenges. Stigmatization affects not only the individual who suffers from a mental illness but also other family members via stigma by association and vicarious stigma. Stigma by association occurs when mental illness stigma spills over to individuals associated with an individual with a mental illness. Vicarious stigma describes the suffering of family members when they note the impact of stigma on their relative with mental illness. As a societal phenomenon, stigma plays out in social interactions and might therefore influence the social networks of families. It is also associated with healthcare utilization.Methods: Narrative interviews were conducted with 15 family members(partners, spouses, parents and children) of former soldiers of the German Armed Forces with a service-induced mental illness. The transcribed interview data were analyzed using a thematic analysis approach, in which codes were formed and emerging themes were systemized. Relationships between stigma, the families’ reactions to it, its effects on their social relationships and its interference with their healthcare utilization were analyzed.Results: This study provides a detailed description of how relatives of former German soldiers with mental health problems experience stigma by association and vicarious stigma. Their perceptions are shown in a model that describes stigma-related attitudes, reactions to them and their effects on the social relationships of former soldiers’ families. These families felt stigmatized because of the former soldiers’ mental illness(mental illness stigma) and the military context in which it occurred(former soldier stigma). They reacted with nondisclosure, anger, acceptance and self-blame. Stigma was associated with smaller and weaker social networks that were characterized by social exclusion, self-segregation and conflicts with extended family, friends and colleagues. Stigma also affected the families’ healthcare utilization.Conclusions: Urgently needed anti-stigma campaigns, particularly in the civilian context, should address the stigmatization of both mental illness and the military participation of the families affected. They should consider the needs of both former soldiers with a mental illness and their families. 展开更多
关键词 STIGMA by association Vicarious STIGMA families MENTAL illness VETERAN German Armed Forces
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HOLOMORPHIC INTERGATED MILD C-EXISTENCE FAMILIES
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作者 高明杵 《Acta Mathematica Scientia》 SCIE CSCD 1998年第1期63-73,共11页
By defined holomorphic n-times integrated mild C-existence families and Csemigroups, their relationship with holomorphic mild C1-exustence families and holomorphic C1 -semigroups is discussed, respectively. For expone... By defined holomorphic n-times integrated mild C-existence families and Csemigroups, their relationship with holomorphic mild C1-exustence families and holomorphic C1 -semigroups is discussed, respectively. For exponentially bounded cases, this papergives several Hille-Yosida type conditions for an operator to have (or generate) one of thesefamilies of operators and generalize the corresponding results in [1], [2] and [3]. These families by the holomorphic solvability of the abstract Cauchy problem is also characterized. 展开更多
关键词 HOLOMORPHIC INTEGRATED MILD C-existence families C-SEMIGROUPS
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On Eigenvalues Locations of Symmetric Matrix Families
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作者 段广仁 王民智 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 1994年第1期42-45,共4页
OnEigenvaluesLocationsofSymmetricMatrixFamiliesDUANGuangren;WANGMinzhi(段广仁,王民智)(Detp.ofControlEngineering,Ha... OnEigenvaluesLocationsofSymmetricMatrixFamiliesDUANGuangren;WANGMinzhi(段广仁,王民智)(Detp.ofControlEngineering,HarbinInsituteofTec... 展开更多
关键词 ss: SYMMETRIC matrix families positive DEFINITENESS HURWITZ STABILITY Shur STABILITY aperiodicity
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A Note on Quadratic Stability of Matrix Families 
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作者 段广仁 胡文远 王忠贤 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 1996年第1期26-28,共3页
ANoteonQuadraticStabilityofMatrixFamiliesDUANGuangren;HUWenyuan;WANGZhongxian(段广仁);(胡文远);(王忠贤)(Dept.ofContro... ANoteonQuadraticStabilityofMatrixFamiliesDUANGuangren;HUWenyuan;WANGZhongxian(段广仁);(胡文远);(王忠贤)(Dept.ofControlEngineering,Harb... 展开更多
关键词 ss: MATRIX families QUADRATIC STABILITY ROBUSTNESS
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Novel mutations in PDE6A and CDHR1 cause retinitis pigmentosa in Pakistani families
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作者 Muhammad Dawood Siying Lin +12 位作者 Taj Ud Din Irfan Ullah Shah Niamat Khan Abid Jan Muhammad Marwan Komal Sultan Maha Nowshid Raheel Tahir Asif Naveed Ahmed Muhammad Yasin Emma LBaple Andrew HCrosby Shamim Saleha 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2021年第12期1843-1851,共9页
AIM:To investigate the genetic basis of autosomal recessive retinitis pigmentosa(arRP)in two consanguineous/endogamous Pakistani families.METHODS:Whole exome sequencing(WES)was performed on genomic DNA samples of pati... AIM:To investigate the genetic basis of autosomal recessive retinitis pigmentosa(arRP)in two consanguineous/endogamous Pakistani families.METHODS:Whole exome sequencing(WES)was performed on genomic DNA samples of patients with arRP to identify disease causing mutations.Sanger sequencing was performed to confirm familial segregation of identified mutations,and potential pathogenicity was determined by predictions of the mutations’functions.RESULTS:A novel homozygous frameshift mutation[NM_000440.2:c.1054delG,p.(Gln352Argfs*4);Chr5:g.149286886del(GRCh37)]in the PDE6A gene in an endogamous family and a novel homozygous splice site mutation[NM_033100.3:c.1168-1G>A,Chr10:g.85968484G>A(GRCh37)]in the CDHR1 gene in a consanguineous family were identified.The PDE6A variant p.(Gln352Argfs*4)was predicted to be deleterious or pathogenic,whilst the CDHR1 variant c.1168-1G>A was predicted to result in potential alteration of splicing.CONCLUSION:This study expands the spectrum of genetic variants for arRP in Pakistani families. 展开更多
关键词 autosomal recessive retinitis pigmentosa PDE6A CDHR1 VARIANTS Pakistani families
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RNA-Seq and Bulked Segregant Analysis of Genes Related to High Growth in <i>Ginkgo biloba</i>Half-Sibling Families
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作者 Limin Sun Haixia Tang +3 位作者 Xiaoyan Men Qian Zhang Xia Sun Shiyan Xing 《American Journal of Plant Sciences》 2019年第1期79-100,共22页
The lifetime of G. biloba is very long, and its growth is relatively slow. However, little is known about growth-related genes in this species. We combined mRNA sequencing (RNA-Seq) with bulked segregant analysis (BSA... The lifetime of G. biloba is very long, and its growth is relatively slow. However, little is known about growth-related genes in this species. We combined mRNA sequencing (RNA-Seq) with bulked segregant analysis (BSA) to fine map significant agronomic trait genes by developing polymorphism molecular markers at the transcriptome level. In this study, transcriptome sequencing of high growth (GD) and low growth (BD) samples of G. biloba half-sib families was performed. After assembling the clean reads, 601 differential expression genes were detected and 513 of them were assigned functional annotations. Single nucleotide polymorphism (SNP) analysis identified SNPs associated with 119 genes in the GD and BD groups;58 of these genes were annotated. Two Homeobox-leucine zipper protein genes were up-regulated in the GD group compared with the BD group;therefore, these are very likely related to high growth of G. biloba. This study provides molecular level data that could be used for seed selection of high growth G. biloba half-sib families for future breeding programs. 展开更多
关键词 High Growth GINKGO biloba Half-Sibling families RNA-SEQ and Bulked Segregant Analysis the Transcriptome Sequencing Differentially Expressed Genes
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Outbreak Information Delivery to Families with (Pre)School Children and Its Contribution
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作者 Tamie Sugawara Yasushi Ohkusa Michiko Nohora 《Journal of Biosciences and Medicines》 2019年第12期31-43,共13页
Background: Infection transmission among them occurs easily and sometimes causes outbreaks at facilities where children live in groups. Early response is necessary for infection control measures to avoid larger cluste... Background: Infection transmission among them occurs easily and sometimes causes outbreaks at facilities where children live in groups. Early response is necessary for infection control measures to avoid larger clusters. In Japan, (Nursery) School Absenteeism Surveillance System ((N)SASSy), which is a kind of school absenteeism surveillance, has activated since 2007 and covers about 60% of all schools and 40% of all nursery schools in 2017. Objective: The objective of the present paper is investigation and demonstration of how caregivers receive information related to infectious diseases in Japan and how (N)SASSy contributes health of children. Method: We randomly selected subjects with children by pre-fecture in October, 2017. The survey questionnaire asked background information and information about infectious diseases to maintain health in children. We regressed health concern variables on background information and information provision situation about community outbreaks using weighted logistic regression. Results: We received responses from 1172 people. Estimation results showed higher concern about a facility providing information about community outbreak. Caregivers whose children attend facilities provided about community outbreak or covered (N)SASSy significantly higher opportunity to arrange a schedule when a child has a high fever. Discussion: The obtained results demonstrated that activation in (N)SASSy affects the possibility of arranging a schedule when a child has a high fever. This capability might improve community health. 展开更多
关键词 SCHOOL ABSENTEEISM SURVEILLANCE OUTBREAK Information families with (Pre)School Children NURSERY SCHOOL Infection Control
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